Syndecan 1 (SDC1) (NM_002997) Human Untagged Clone

CAT#: SC118272

SDC1 (untagged)-Human syndecan 1 (SDC1), transcript variant 2


  "NM_002997" in other vectors (4)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol SDC1
Synonyms CD138; SDC; SYND1; syndecan
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_002997 edited
GAATTCGGCACGAGGCCGAATCCGAGCCGAGCGGAGAGGAATCCGGCAGTAGAGAGCGGA
CTCCAGCCGGCGGACCCTGCAGCCCTCGCCTGGGACAGCGGCGCGCTGGGCAGGCGCCCA
AGAGAGCATCGAGCAGCGGAACCCGCGAAGCCGGCCCGCAGCCGCGACCCGCGCAGCCTG
CCGCTCTCCCGCCGCCGGTCCGGGCAGCATGAGGCGCGCGGCGCTCTGGCTCTGGCTGTG
CGCGCTGGCGCTGAGCCTGCAGCCGGCCCTGCCGCAAATTGTGGCTACTAATTTGCCCCC
TGAAGATCAAGATGGCTCTGGGGATGACTCTGACAACTTCTCCGGCTCAGGTGCAGGTGC
TTTGCAAGATATCACCTTGTCACAGCAGACCCCCTCCACTTGGAAGGACACGCAGCTCCT
GACGGCTATTCCCACGTCTCCAGAACCCACCGGCCTGGAGGCTACAGCTGCCTCCACCTC
CACCCTGCCGGCTGGAGAGGGGCCCAAGGAGGGAGAGGCTGTAGTCCTGCCAGAAGTGGA
GCCTGGCCTCACCGCCCGGGAGCAGGAGGCCACCCCCCGACCCAGGGAGACCACACAGCT
CCCGACCACTCATCAGGCCTCAACGACCACAGCCACCACGGCCCAGGAGCCCGCCACCTC
CCACCCCCACAGGGACATGCAGCCTGGCCACCATGAGACCTCAACCCCTGCAGGACCCAG
CCAAGCTGACCTTCACACTCCCCACACAGAGGATGGAGGTCCTTCTGCCACCGAGAGGGC
TGCTGAGGATGGAGCCTCCAGTCAGCTCCCAGCAGCAGAGGGCTCTGGGGAGCAGGACTT
CACCTTTGAAACCTCGGGGGAGAATACGGCTGTAGTGGCCGTGGAGCCTGACCGCCGGAA
CCAGTCCCCAGTGGATCAGGGGGCCACGGGGGCCTCACAGGGCCTCCTGGACAGGAAAGA
GGTGCTGGGAGGGGTCATTGCCGGAGGCCTCGTGGGGCTCATCTTTGCTGTGTGCCTGGT
GGGTTTCATGCTGTACCGCATGAAGAAGAAGGACGAAGGCAGCTACTCCTTGGAGGAGCC
GAAACAAGCCAACGGCGGGGCCTACCAGAAGCCCACCAAACAGGAGGAATTCTATGCCTG
ACGCGGGAGCCATGCGCCCCCTCCGCCCTGCCACTCACTAGGCCCCCACTTGCCTCTTCC
TTGAAGAACTGCAGGCCCTGGCCTCCCCTGCCACCAGGCCACCTCCCCAGCATTCCAGCC
CCTCTGGTCGCTCCTGCCCACGGAGTCGTGGGGTGTGCTGGGAGCTCCACTCTGCTTCTC
TGACTTCTGCCTGGAGACTTAGGGCACCAGGGGTTTCTCGCATAGGACCTTTCCACCACA
GCCAGCACCTGGCATCGCACCATTCTGACTCGGTTTCTCCAAACTGAAGCAGCCTCTCCC
CAGGTCCAGCTCTGGAGGGGAGGGGGATCCGACTGCTTTGGACCTAAATGGCCTCATGTG
GCTGGAAGATCCTGCGGGTGGGGCTTGGGGCTCACACACCTGTAGCACTTACTGGTAGGA
CCAAGCATCTTGGGGGGGTGGCCGCTGAGTGGCAGGGGACAGGAGTCCACTTTGTTTCGT
GGGGAGGTCTAATCTAGATATCGACTTGTTTTTGCACATGTTTCCTCTAGTTCTTTGTTC
ATAGCCCAGTAGACCTTGTTACTTCTGAGGTAAGTTAAGTAAGTTGATTCGGTATCCCCC
CATCTTGCTTCCCTAATCTATGGTCGGGAGACAGCATCAGGGTTAAGAAGACTTTTTTTT
TTTTTTTTXXXXXXXXXXXXXXXXXXXXXAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACTCGAC
>OriGene 5' read for NM_002997 unedited
CGGGTAGCATTTGTATACGACTTATATAGGGCGGCCGCGAATTCGCACGAGGCCGAATCC
GAGCCGAGCGGAGAGGAATCCGGCAGTAGAGAGCGGACTCCAGCCGGCGGACCCTGCAGC
CCTCGCCTGGGACAGCGGCGCGCTGGGCAGGCGCCCAAGAGAGCATCGAGCAGCGGAACC
CGCGAAGCCGGCCCGCAGCCGCGACCCGCGCATCCTGCCGCTCTCCCGCCGCCGGTCCGG
GCAGCATGAGGCGCGCGGCGCTCTGGCTCTGGCTGTGCGCGCTGGCGCTGAGCCTGCAGC
CGGCCCTGCCGCAAATTGTGGCTACTAATTTGCCCCCTGAAGATCAAGATGGCTCTGGGG
ATGACTCTGACAACTTCTCCGGCTCAGGTGCAGGTGCTTTGCAAGATATCACCTTGTCAC
AGCAGACCCCCTCCACTTGGAAGGACACGCAGCTCCTGACGGCTATTCCCACGTCTCCAG
AACCCACCGGCCTGGAGGCTACAGCTGCCTCCACCTCCACCCTGCCGGCTGGAGAGGGGC
CCAAGGAGGGAGAGGCTGTAGTCCTGCCAGAAGTGGAGCCTGGCCTCACCGCCCGGGAGC
AGGAGGCCACCCCCCGACCCAGGGAGACCACACAGCTCCCGACCACTCATCAGGCCTCAA
CGACCACAGCCACCACGGCCCAGGAGCCCGCCACCTCCCACCCNCACAGGGACATGCAGC
CTGGCCACCATGAGACCTCAACCCCTGCAGGACCCAGCCAAGCTGACCTTCACACTCCCC
ACACAGAGGATGGGAGTCCTTCTGCCANCGAGAGGGCTGCTNGAGATGGAGCCTNCAGTC
AGCTCCCAGCACAGAGGGCTCTNGGGGAGCAGACTTTCACTTTGAACCTCCGGGGAGAAT
ACGCTGTATGG
>OriGene 3' read for NM_002997 unedited
CTCCCCCNAATTGACTTGNACCGCGCCCGTATNCTAGNGATCNGTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTC
CCGGGCCCCCTTTTTTTAAAAGTTTATTCCTTTGGGAAAACCTCCGGGCCGGGGAAAAAC
CCCTTTGGATAAAATAAAGTTTTCCCAAAACCAAAAAACTTTTTCTTTTTGGAAAATTTT
CCTGATCCCCCCCCAGGGCCCAGGGGGGGCCCCCGGGGCCTACCGGAAAACCTGCCCTTG
GATGGGGGCCCTAAAAACCAGCTTTGCCCAAAAACCCCCCTCGTTAATTTCCCGGGGGAA
ACCCCCCCCGGGGAACGGCCCCCCCGGCCAAGAAGGGGGGGTTTTTTCAAGAAAAATTTT
TTAGGGCCCCGGGGGCGCCCCCCCAAAAAGGTCTCTTTTGTGGGGGGGGGGGGGGGGCCC
CCCATTTTTTTTTTTTTCCCCGGGGGGTGTTTTCTCCAAGGGGGGGGGGCGGCCCCCCCC
CCCCCAAAGAGAGGGGGTCGGCGGGGGGGCGGGCCCCCCCCCCCTTTTTTTTTTTATAAG
AAGGGGGGCCCCCCCCCCCCCCCCGCCAGAGTGGGGGGGGGGGGGGCCCCCAAAAAAAAA
AAAAAAAAAAAGGAGAGGGGGGCGCCGCCCCACACAAAAAAACAAAACACCCCCGCTGGG
GGGCGGTCGTTGAGGGCGCCCCGCCNCNCTCCACACACAAACACACCCCCACCACCCCCC
CCCCCAACCCCCGCGCCCGGGGGGGGCGGGGGGGGGGGGGGGGGCCCCCCGCCNAAAAAA
AAAAAAAAAAAAAAAAAAAAAAGTTTGTTTGTGGGGCTGGCGCGTCCCGCCCCCCCCAAC
AACAACACAAAAAAAAAAAGGGAGGGGCGCGGGGGGGGCGGCGCGCGTTCTTCC
Restriction Sites NotI-NotI     
ACCN NM_002997
ORF Size 933 bp
Insert Size 2500
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Reference Data
RefSeq NM_002997.4, NP_002988.3
RefSeq Size 3217
RefSeq ORF 933
Locus ID 6382
Domains Syndecan
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs), ECM-receptor interaction
Gene Summary The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008]
Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.

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