SDHC (NM_003001) Human Untagged Clone

CAT#: SC118274

SDHC (untagged)-Human succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa (SDHC), nuclear gene encoding mitochondrial protein, transcript variant 1


  "NM_003001" in other vectors (6)

Reconstitution Protocol

USD 420.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol SDHC
Synonyms CYB560; CYBL; PGL3; QPS1; SDH3
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF sequence for NM_003001 edited
ATGGCTGCGCTGTTGCTGAGACACGTTGGTCGTCATTGCCTCCGAGCCCACTTTAGCCCT
CAGCTCTGTATCAGAAATGCTGTTCCTTTGGGAACCACGGCCAAAGAAGAGATGGAGCGG
TTCTGGAATAAGAATATAGGTTCAAACCGTCCTCTGTCTCCCCACATTACTATCTACAGT
TGGTCTCTTCCCATGGCGATGTCCATCTGCCACCGTGGCACTGGTATTGCTTTGAGTGCA
GGGGTCTCTCTTTTTGGCATGTCGGCCCTGTTACTCCCTGGGAACTTTGAGTCTTATTTG
GAACTTGTGAAGTCCCTGTGTCTGGGGCCAGCACTGATCCACACAGCTAAGTTTGCACTT
GTCTTCCCTCTCATGTATCATACCTGGAATGGGATCCGACACTTGATGTGGGACCTAGGA
AAAGGCCTGAAGATTCCCCAGCTATACCAGTCTGGAGTGGTTGTCCTGGTTCTTACTGTG
TTGTCCTCTATGGGGCTGGCAGCCATGTGA
>OriGene 5' read for NM_003001 unedited
CCGCGAATTCGGCACGAGCCGGAACCCAAGATGGCTGCGCTGTTGCTGAGACACGTTGGT
CGTCATTGCCTCCGAGCCCACTTTAGCCCTCAGCTCTGTATCAGAAATGCTGTTCCTTTG
GGAACCACGGCCAAAGAAGAGATGGAGCGGTTCTGGAATAAGAATATAGGTTCAAACCGT
CCTCTGTCTCCCCACATTACTATCTACAGTTGGTCTCTTCCCATGGCGATGTCCATCTGC
CACCGTGGCACTGGTATTGCTTTGAGTGCAGGGGTCTCTCTTTTTGGCATGTCGGCCCTG
TTACTCCCTGGGAACTTTGAGTCTTATTTGGAACTTGTGAAGTCCCTGTGTCTGGGGCCA
GCACTGATCCACACAGCTAAGTTTGCACTTGTCTTCCCTCTCATGTATCATACCTGGAAT
GGGATCCGACACTTGATGTGGGACCTAGGAAAAGGCCTGAAGATTCCCCAGCTATACCAG
TCTGGAGTGGTTGTCCTGGTTCTTACTGTGTTGTCCTCTATGGGGCTGGCAGCCATGTGA
AGAAAGGAGGCTCCCAGCATCATCTTCCTACACATTATTACATTCACCCATCTTTCTGTT
TGTCATTCTTATCTCCAGCCTGGGAAAAGTTCTCCTTATTTGGTTAGATCCTTTTGTATT
TTCAGATCTCCTTGGAGCAGTAGAGTACCTGGTAGACCATAATAGTGGAAAAGGGTCTAG
TTTTTCCCTTTGGTTCTAAGATGAGGT
>OriGene 3' read for NM_003001 unedited
CCCCCATTCCTTGCCCGCGGCCGCATTCTACGAGCGAGTTTTTTTTTTTTTTTTTTTTTA
AAATGAGTATTTAATTCAGTTTCAGAAAAAAGGGTACATTACTTCGATGAGAAGCATAAA
ATTAAGAGGCTTTTCTGGAAATCCAAGAAAAAGAAATAACCATTAATATGTTCAATGATA
ATTTTCTAGATCTTCCTCGTGTCCAAAGCTATATATTTTCTCCTCAAAAGCAGCTGCTCC
AAGAACTAACTAGCCCTCTTTATCTCCCTCTAGCTGGGACAGACTAATTCCCCTCCACCC
CCACCTCTCTTCTTTCAATAACACTGTGTAGGTGTTAATGGCCTGGGCTCTCACCAATGA
AGAGAATTGTCCTTTAAGCCAGCAACCCACAGGCAGTGGCACCCAAAGCCTCACCAACCC
ACCCCCCAACCCGGCCTATCCCCAGGGCAGAAGCCACAGAGCTGGCATTGTTTCCACTGT
CTCAGGAAGAAGGAGCCAAAAGCTGACCTTTAGTACAAATTAAAGCCCAATATGGAGAGA
GAATAACTGATTTTAGGCTTAGAGTAGGCAAGCTGCGGGCCAAAAAGGGGAGTTTTTGCT
GCCTCTTCATTTTTTTAGACAGGGGGAAAACTAGACCCTTTTCCCTTATTACGGTCTACC
AGGCCCTTTCCTGGTTTCAGGAGAACTGACAATCCACACGGATTTAACCAAAAAAGGCGA
ACTTTTCCCACGCTGGAAAAATAATGACCACCCCACCACCGGTTAATGCTATACCGCGCC
CCAAAATTATCCTTGGCAGCTTTACTTTTTTCCCCTGGTAGCCCACCCCCTCCGTGGTCT
ACCATTCACCTACACGCAAACTCCTCACACCGGCTCGTTTGACAACATCCTGGCCTCCTC
CCCCACCCCCCG
Restriction Sites NotI-NotI     
ACCN NM_003001
Insert Size 1200 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_003001.2, NP_002992.1
RefSeq Size 1315 bp
RefSeq ORF 510 bp
Locus ID 6391
Cytogenetics 1q23.3
Domains Sdh_cyt
Protein Families Druggable Genome, Transmembrane
Protein Pathways Alzheimer's disease, Citrate cycle (TCA cycle), Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease
Gene Summary 'This gene encodes one of four nuclear-encoded subunits that comprise succinate dehydrogenase, also known as mitochondrial complex II, a key enzyme complex of the tricarboxylic acid cycle and aerobic respiratory chains of mitochondria. The encoded protein is one of two integral membrane proteins that anchor other subunits of the complex, which form the catalytic core, to the inner mitochondrial membrane. There are several related pseudogenes for this gene on different chromosomes. Mutations in this gene have been associated with paragangliomas. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2013]'
Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

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