MCP1 (CCL2) (NM_002982) Human Untagged Clone

CAT#: SC118317

CCL2 (untagged)-Human chemokine (C-C motif) ligand 2 (CCL2)


  "NM_002982" in other vectors (6)

Reconstitution Protocol

USD 310.00

In Stock*

Size
    • 10 ug

Product Images

Other products for "CCL2"

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol CCL2
Synonyms GDCF-2; HC11; HSMCR30; MCAF; MCP-1; MCP1; SCYA2; SMC-CF
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC118317 sequence for NM_002982 edited (data generated by NextGen Sequencing)
ATGAAAGTCTCTGCCGCCCTTCTGTGCCTGCTGCTCATAGCAGCCACCTTCATTCCCCAA
GGGCTCGCTCAGCCAGATGCAATCAATGCCCCAGTCACCTGCTGTTATAACTTCACCAAT
AGGAAGATCTCAGTGCAGAGGCTCGCGAGCTATAGAAGAATCACCAGCAGCAAGTGTCCC
AAAGAAGCTGTGATCTTCAAGACCATTGTGGCCAAGGAGATCTGTGCTGACCCCAAGCAG
AAGTGGGTTCAGGATTCCATGGACCACCTGGACAAGCAAACCCAAACTCCGAAGACTTGA

Clone variation with respect to NM_002982.3
>OriGene 5' read for NM_002982 unedited
GGGGTAGATTTGTAACACGATTCACTATAGGGCGGCCGCGAAATCGGCACGAGGTAACCC
AGAACATCCAATTCTCAAACTGAAGCTCGCACTCTCGCCTCCAGCATGAAAGTCTCTGCC
GCCCTTCTGTGCCTGCTGCTCATAGCAGCCACCTTCATTCCCCAAGGGCTCGCTCAGCCA
GATGCAATCAATGCCCCAGTCACCTGCTGTTATAACTTCACCAATAGGAAGATCTCAGTG
CAGAGGCTCGCGAGCTATAGAAGAATCACCAGCAGCAAGTGTCCCAAAGAAGCTGTGATC
TTCAAGACCATTGTGGCCAAGGAGATCTGTGCTGACCCCAAGCAGAAGTGGGTTCAGGAT
TCCATGGACCACCTGGACAAGCAAACCCAAACTCCGAAGACTTGAACACTCACTCCACAA
CCCAAGAATCTGCAGCTAACTTATTTTCCCCTAGCTTTCCCCAGACACCCTGTTTTATTT
TATTATAATGAATTTTGTTTGTTGATGTGAAACATTATGCCTTAAGTAATGTTAATTCTT
ATTTAAGCTATTGATGTTTTAAGTTATCTTTCATGGTACTAGCGCTTTCTACATACAGAG
ACTTGGGGGAAATTGCTTTTCCTCTTGAACCACAGTTCTACCCCCTGGGATGCTTTGAGG
GTCTTTGCAAGATCATTAATACAAAGAATTTTTTTTAACATTCCCAAGCATTGCTAAAAT
AATATTGCGGAAATGAATATTTTGGAACCATTACCCCAAACAAATATATTTTTTGTACAA
AAAAAAAAAAAAAACCTTACTTCTAAATTGAGCCCCGGCCCATTCTTTCCCCTGACCACA
CCCCCGTGGGCTCCCTGTGAACCTCCCCCAATGCCCTTCCTGNCCCTGAAAGTTGCCATT
CCATGCGCCACACCCCTGGCT
>OriGene 3' read for NM_002982 unedited
CAATCTAGTATCGAGTTTTTTTTTTTTTTTTTTGTACAAAAATATATTTATTTGGTGTAA
TAGTTACAAAATATTCATTTCCACAATAATATTTTAGCAATGCATTGGAATGTTAAAAAA
AATTCTTTGTATTAATGATTCTTGCAAAGACCCTCAAAACATCCCAGGGGTAGAACTGTG
GTTCAAGAGGAAAAGCAATTTCCCCAAGTCTCTGTATCTAAAAAACACTAGTACCATGAA
AGATAAACTTAAAACATCAATAACTTAAATAAGAATTAACATTACTTAAGGCATAATGTT
TCACATCAACAAACAAAATTCATTATAATAAAATAAAACAGGGTGTCTGGGGAAAGCTAG
GGGAAAATAAGTTAGCTGCAGATTCTTGGGTTGTGGAGTGAGTGTTCAAGTCTTCGGAGT
TTGGGTTTGCTTGTCCAGGTGGTCCATGGAATCCTGAACCCACTTCTGCTTGGGGTCAGC
ACAGATCTCCTTGGCCACAATGGTCTTGAAGATCACAGCTTCTTTGGGACACTTGCTGCT
GGAGATTCTTCTATAGCTCGCGAGCCTCTGCACTGAGATCTTCCTATTGGTGAAGTTATA
ACAGCAGGTGACTGGNGCATTGATTGCATCTGGCTGAGCGAGCCCTTGGGGAATGAAGGT
GGCTGCTATGAGCAGCAGGCACATGATGGCCGCAGATACTCTCATGCNTGNAGCGAGAGT
GCCAGCCTTAGTTTGAGAATTGGATGTTTCCTGGGTTACCTCGTGCCCGATTTCCCGGCC
GCCCTATAGTGAGTCGTATTACAAAATCCTGACGGTTCACTAAACGAGCTCTGCCTATTT
AGACTNCCACCGACACGCCTACGNCCATTTGTGTAACGGGGCCGGGTTTTACGACTTTCG
GAAGTCCCGTGTTTTGTTGCAAAAAATTCACTGCGTCATGGGTGAGACTCGAATCCCGGG
GGTAAACGCTTCAGCCCTTGTGTCTGCAAAACGTTACATGTATG
Restriction Sites NotI-NotI     
ACCN NM_002982
Insert Size 700 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_002982.3, NP_002973.1
RefSeq Size 760 bp
RefSeq ORF 300 bp
Locus ID 6347
Cytogenetics 17q12
Domains IL8
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Chemokine signaling pathway, Cytokine-cytokine receptor interaction, NOD-like receptor signaling pathway
Gene Summary 'This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection. [provided by RefSeq, Aug 2020]'

Other Versions

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.