RAC2 (NM_002872) Human Untagged Clone

CAT#: SC118358

RAC2 (untagged)-Human ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) (RAC2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RAC2
• Synonyms: EN-7; Gx; HSPC022; p21-Rac2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC118358 sequence for NM_002872 edited (data generated by NextGen Sequencing)
  ATGCAGGCCATCAAGTGTGTGGTGGTGGGAGATGGGGCCGTGGGCAAGACCTGCCTTCTC
  ATCAGCTACACCACCAACGCCTTTCCCGGAGAGTACATCCCCACCGTGTTTGACAACTAT
  TCAGCCAATGTGATGGTGGACAGCAAGCCAGTGAACCTGGGGCTGTGGGACACTGCTGGG
  CAGGAGGACTACGACCGTCTCCGGCCGCTCTCCTATCCACAGACGGACGTCTTCCTCATC
  TGCTTCTCCCTCGTCAGCCCAGCCTCTTATGAGAACGTCCGCGCCAAGTGGTTCCCAGAA
  GTGCGGCACCACTGCCCCAGCACACCCATCATCCTGGTGGGCACCAAGCTGGACCTGCGG
  GACGACAAGGACACCATCGAGAAACTGAAGGAGAAGAAGCTGGCTCCCATCACCTACCCG
  CAGGGCCTGGCACTGGCCAAGGAGATTGACTCGGTGAAATACCTGGAGTGCTCAGCTCTC
  ACCCAGAGAGGCCTGAAAACCGTGTTCGACGAGGCCATCCGGGCCGTGCTGTGCCCTCAG
  CCCACGCGGCAGCAGAAGCGCGCCTGCAGCCTCCTCTAG
  
  Clone variation with respect to NM_002872.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002872 unedited
  NTGTTCANAATTTTGTAATACGACTCACTTATAGGGCGGCCGCGAATTCGCACGAGGGCT
  GTCACCACCGACACTCTCCAGGCTCCGGACACGATGCAGGCCATCAAGTGTGTGGTGGTG
  GGAGATGGGGCCGTGGGCAAGACCTGCCTTCTCATCAGCTACACCACCAACGCCTTTCCC
  GGAGAGTACATCCCCACCGTGTTTGACAACTATTCAGCCAATGTGATGGTGGACAGCAAG
  CCAGTGAACCTGGGGCTGTGGGACACTGCTGGGCAGGAGGACTACGACCGTCTCCGGCCG
  CTCTCCTATCCACAGACGGACGTCTTCCTCATCTGCTTCTCCCTCGTCAGCCCAGCCTCT
  TATGAGAACGTCCGCGCCAAGTGGTTCCCAGAAGTGCGGCACCACTGCCCCAGCACACCC
  ATCATCCTGGTGGGCACCAAGCTGGACCTGCGGGACGACAAGGACACCATCGAGAAACTG
  AAGGAGAAGAAGCTGGCTCCCATCACCTACCCGCAGGGCCTGGCACTGGCCAAGGAGATT
  GACTCGGTGAAATACCTGGAGTGCTCAGCTCTCACCCAGAGAGGCCTGAAAACCGTGTTC
  GACGAGGCCATCCGGGCCGTGCTGTGCCCTCAGCCCACGCGGCAGCAGAAGCGCGCCTGC
  AGCCTCCTCTAGGGGTTGCACCCCAGCGCTCCCACCTAGATGGGTCTGATCCTCCCAGAT
  CCCCACCCAAAGCCTGATGGCACCCCGGCTGGCCATGCTGTCCCCTCCTGTGGCGTTTCT
  TAACAGATGGCTGCAGAGCTTCGTTGATGGTCTTTTCTGTACTGGAGGCCTNCTGAGCCA
  NGAACGTGCAATTTGCAGTGCTGCATNCCAAGCCCTCATGCTCTGCTTCTGAGGCCAGAG
  GNGAGCCCAGACCATTAGCC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002872 unedited
  CCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGAATCAATAAATTTATTTTCTGCT
  TAAGCAGGTTGAGTTGGGTTTTCTATTTGCAATAGCAAAAGTCCTGACTGGCAAGGTTTA
  AAAGTTTGAAGACTCTCACAGGTAAGTGCAGCTCAAGATCCTGTGAGTGCAGCAGAAAGT
  CTTAAGAAATGGCAGGGGCTGGTTGAACCCATATTTTCCATTGGCTGAGCAGATATCCCC
  AGAGGCGTAGAAAATTAAATTTGTTTTATGTTGTTCCAAAAGAGGAGAACTGAGGCCAGA
  GGAGCACACTTCTGAGACACTCATTTTTGCTGGGTAGAGGAACTCTCTGGCAAGCAGGAC
  CATCGATATTAGAGCAGCTGGCCTCAGGAGGGAGTAAGAGCCCCATCCCTGAAGGTACAC
  AAGTTGTGGCAGCAACCATCTGGCCTGCAGTTTCCATAGGGGAGTCATGCGTGGGGTGGG
  ACTGGAGTGAACGGGTAGATGCTTCCACATGCGGCAGTTGGCACTGACGGCAGGAACACG
  GAGGTGGCTTAATGGGTCCTGAGGCTCCCCTCTGGCCCTCATGAAGGCAGGAGCATGATG
  GGCTTGNGATGCATCACCTGCAAATTTGCACGTTCCTGGCCTCATGATGCCTNCAGTACA
  GAAAAGACCATCAACGAAGCTCTGCAGCCATCTGCTAAGAAACGCCACATGGAGGGGACA
  GCATGGCCAGCCCGGGTGCCATCAGGCTTTGGGTGGGGATCCTGGNAGATCANACCCATC
  TATGTGGGAGCGCTGGGGTGCACCNCTATAGGAGCTGCANGCGCGCTTCTGCTGCCGCGT
  GGGCTGATGCACATCACGGCCGGNATGGCTCGTCGAACACGTTTNAGGCCTCTCTGGGTG
  AGAGCTGACACTTCCAGTTTTCACCGGTNAATCTCCTGGCCNTGCCAGNCCTGCGGTAGT
  GATGGAGCANCTCTTTNCTCATTCTCGAGGGCCTN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_002872
• ORF Size: 579 bp
• Insert Size: 1530
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_002872.3, NP_002863.1
• RefSeq Size: 1516
• RefSeq ORF: 579
• Locus ID: 5880
• Domains: ras, RAN, RAS, RHO, RAB
• Protein Families: Druggable Genome
• Protein Pathways: Adherens junction, Axon guidance, B cell receptor signaling pathway, Chemokine signaling pathway, Colorectal cancer, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, Leukocyte transendothelial migration, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Pancreatic cancer, Pathways in cancer, Regulation of actin cytoskeleton, VEGF signaling pathway, Viral myocarditis, Wnt signaling pathway
• Gene Summary: This gene encodes a member of the Ras superfamily of small guanosine triphosphate (GTP)-metabolizing proteins. The encoded protein localizes to the plasma membrane, where it regulates diverse processes, such as secretion, phagocytosis, and cell polarization. Activity of this protein is also involved in the generation of reactive oxygen species. Mutations in this gene are associated with neutrophil immunodeficiency syndrome. There is a pseudogene for this gene on chromosome 6. [provided by RefSeq, Jul 2013]