PTP gamma (PTPRG) (NM_002841) Human Untagged Clone

CAT#: SC118366

PTPRG (untagged)-Human protein tyrosine phosphatase, receptor type, G (PTPRG)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PTPRG
• Synonyms: HPTPG; PTPG; R-PTP-GAMMA; RPTPG
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_002841, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCGGAGGTTACTGGAACCGTGTTGGTGGATTTTGTTCCTGAAAATCACCAGTTCCGTGCTCCATTATG
  TCGTGTGCTTCCCCGCGTTGACAGAAGGCTACGTTGGGGCCCTGCACGAGAATAGACACGGCAGCGCAGT
  GCAGATCCGCAGGCGCAAGGCTTCAGGCGACCCGTACTGGGCCTACTCTGGTGCCTATGGTCCTGAGCAC
  TGGGTCACGTCTAGTGTCAGCTGTGGGGGCCGTCACCAGTCTCCTATTGACATTTTAGACCAGTATGCGC
  GTGTTGGGGAAGAATACCAGGAACTGCAACTCGATGGCTTCGACAATGAGTCTTCTAACAAAACCTGGAT
  GAAAAACACAGGGAAAACAGTCGCCATCCTTCTGAAAGACGACTATTTTGTCAGTGGAGCTGGTCTACCT
  GGCAGATTCAAAGCTGAGAAGGTGGAATTTCACTGGGGCCACAGCAATGGCTCAGCGGGCTCTGAACACA
  GCATCAATGGCAGGAGGTTTCCTGTTGAGATGCAGATTTTCTTTTACAATCCAGATGACTTTGACAGCTT
  TCAAACCGCAATTTCTGAGAACAGAATAATCGGAGCCATGGCCATATTTTTTCAAGTCAGTCCGAGGGAC
  AATTCTGCACTGGATCCTATTATCCACGGGTTGAAGGGTGTCGTACATCATGAGAAGGAGACCTTTCTGG
  ATCCTTTCGTCCTCCGGGACCTCCTGCCTGCATCCCTGGGCAGCTATTATCGGTACACAGGTTCCTTGAC
  CACACCACCGTGTAGCGAAATAGTGGAGTGGATAGTCTTCCGGAGACCCGTCCCCATCTCTTACCATCAG
  CTTGAGGCTTTTTATTCCATCTTCACCACGGAGCAGCAAGACCATGTCAAGTCGGTGGAGTATCTGAGAA
  ATAACTTTCGACCACAGCAGCGTCTGCATGACAGGGTGGTGTCCAAGTCCGCCGTCCGTGACTCCTGGAA
  CCACGACATGACAGACTTCTTAGAAAACCCACTGGGGACAGAAGCCTCTAAAGTTTGCAGCTCTCCACCC
  ATCCACATGAAGGTGCAGCCTCTGAACCAGACGGCACTGCAGGTGTCCTGGAGCCAGCCGGAGACTATCT
  ACCACCCACCCATCATGAACTACATGATCTCCTACAGCTGGACCAAGAATGAGGACGAGAAGGAGAAGAC
  GTTTACAAAGGACAGCGACAAAGACTTGAAAGCCACCATTAGCCATGTCTCACCCGATAGCCTTTACCTG
  TTCCGAGTCCAGGCCGTGTGTCGGAACGACATGCGCAGCGACTTTAGCCAGACGATGCTGTTTCAAGCTA
  ATACCACTCGAATATTCCAAGGGACCAGAATAGTGAAAACAGGAGTGCCCACAGCGTCTCCTGCCTCTTC
  AGCCGACATGGCCCCCATCAGCTCGGGGTCTTCTACCTGGACGTCCTCTGGCATCCCATTCTCATTTGTT
  TCCATGGCAACTGGGATGGGCCCCTCCTCCAGTGGCAGCCAGGCCACAGTGGCCTCGGTGGTCACCAGCA
  CGCTGCTCGCCGGCCTGGGGTTCGGCGGTGGTGGCATCTCCTCTTTCCCCAGCACTGTGTGGCCCACGCG
  CCTCCCGACGGCCGCCTCAGCCAGCAAGCAGGCGGCTAGGCCAGTCCTAGCCACCACAGAGGCCTTGGCT
  TCTCCAGGGCCCGATGGTGATTCGTCACCAACCAAGGACGGCGAGGGCACCGAGGAAGGAGAGAAGGATG
  AGAAAAGCGAGAGTGAGGATGGGGAGCGGGAGCACGAGGAGGATGGAGAGAAGGACTCCGAAAAGAAGGA
  GAAGAGTGGGGTGACCCACGCTGCCGAGGAGCGGAATCAGACGGAGCCCAGCCCCACACCCTCGTCTCCT
  AACAGGACTGCCGAGGGAGGGCATCAGACTATACCTGGGCATGAGCAGGATCACACTGCCGTCCCCACAG
  ACCAGACGGGCGGAAGGAGGGATGCCGGCCCAGGCCTGGACCCCGACATGGTCACCTCCACCCAAGTGCC
  CCCCACCGCCACAGAGGAGCAGTATGCAGGGAGTGATCCCAAGAGGCCCGAAATGCCATCTAAAAAGCCT
  ATGTCCCGCGGGGACCGATTTTCTGAAGACAGCAGATTTATCACTGTTAATCCAGCGGAAAAAAACACCT
  CTGGAATGATAAGCCGCCCTGCTCCAGGGAGGATGGAGTGGATCATCCCTCTGATTGTGGTATCAGCCTT
  GACCTTCGTGTGCCTCATCCTTCTCATTGCTGTGCTCGTTTACTGGAGAGGGTGTAACAAAATAAAGTCC
  AAGGGCTTTCCCAGACGTTTCCGTGAAGTGCCTTCTTCTGGGGAGAGAGGAGAGAAGGGGAGCAGAAAAT
  GTTTTCAGACTGCTCATTTCTATGTGGAAGACAGCAGTTCACCTCGAGTGGTCCCTAATGAAAGTATCCC
  TATTATTCCTATTCCGGATGACATGGAAGCCATTCCTGTCAAACAGTTTGTCAAACACATCGGTGAGCTC
  TATTCTAATAACCAGCATGGGTTCTCTGAGGATTTTGAGGAAGTCCAGCGCTGTACTGCTGATATGAACA
  TCACTGCAGAGCATTCCAATCATCCAGAAAACAAGCACAAAAACAGATACATCAACATTTTAGCATATGA
  TCACAGTAGGGTGAAGTTAAGACCTTTACCAGGAAAAGACTCTAAGCACAGCGACTACATTAATGCAAAC
  TATGTTGATGGTTACAACAAAGCAAAAGCCTACATTGCCACCCAAGGACCTTTGAAGTCTACATTTGAAG
  ATTTCTGGAGGATGATTTGGGAACAAAACACTGGAATCATTGTGATGATTACGAACCTTGTGGAAAAAGG
  AAGACGAAAATGTGATCAGTATTGGCCAACAGAGAACAGTGAGGAATATGGAAACATTATTGTCACGCTG
  AAGAGCACAAAAATACATGCCTGCTACACTGTTCGTCGTTTTTCAATCAGAAATACAAAAGTGAAAAAGG
  GTCAGAAGGGAAATCCCAAGGGTCGTCAGAATGAAAGGGTAGTGATCCAGTATCACTATACACAGTGGCC
  TGACATGGGAGTTCCCGAGTATGCCCTTCCAGTACTGACTTTCGTGAGGAGATCCTCAGCAGCTCGGATG
  CCAGAAACGGGCCCTGTGTTGGTGCACTGCAGTGCTGGTGTGGGCAGAACAGGCACCTATATTGTAATAG
  ACAGCATGCTGCAACAGATAAAAGACAAAAGCACAGTTAACGTCCTGGGATTCCTGAAGCATATCAGGAC
  ACAGCGTAACTACCTCGTCCAGACTGAGGAGCAGTACATTTTCATCCATGATGCCTTGTTGGAAGCCATT
  CTTGGAAAGGAGACTGAAGTATCTTCAAATCAGCTGCACAGCTATGTTAACAGCATCCTTATACCAGGAG
  TAGGAGGAAAGACACGACTGGAAAAGCAATTCAAGCTGGTCACACAGTGTAATGCAAAATATGTGGAATG
  TTTCAGTGCTCAGAAAGAGTGTAACAAAGAAAAGAACAGAAACTCTTCAGTTGTGCCATCTGAGCGTGCT
  CGAGTGGGTCTTGCACCATTGCCTGGAATGAAAGGAACAGATTACATTAATGCTTCTTATATCATGGGCT
  ATTATAGGAGCAATGAATTTATTATAACTCAGCATCCTCTGCCACATACTACGAAAGATTTCTGGCGAAT
  GATTTGGGATCATAACGCACAGATCATTGTCATGCTGCCAGACAACCAGAGCTTGGCAGAAGATGAGTTT
  GTGTACTGGCCAAGTCGAGAAGAATCCATGAACTGTGAGGCCTTTACCGTCACCCTTATCAGCAAAGACA
  GACTGTGCCTCTCTAATGAAGAACAAATTATCATCCATGACTTTATCCTTGAAGCTACACAGGATGACTA
  TGTCTTAGAAGTTCGGCACTTTCAGTGTCCCAAATGGCCTAACCCAGATGCCCCCATAAGTAGTACCTTT
  GAACTTATCAACGTCATCAAGGAAGAGGCCTTAACAAGGGATGGTCCCACCATTGTTCATGATGAGTATG
  GAGCAGTTTCAGCAGGAATGTTATGTGCCCTTACCACCCTGTCCCAGCAACTGGAGAATGAAAATGCTGT
  GGATGTTTTCCAGGTTGCAAAAATGATCAATCTTATGAGGCCTGGAGTATTCACAGACATTGAACAATAC
  CAGTTCATCTATAAAGCAATGCTTAGCTTGGTCAGCACTAAAGAAAATGGAAATGGTCCCATGACAGTAG
  ACAAAAATGGTGCTGTTCTTATTGCAGATGAATCAGACCCTGCTGAGAGCATGGAGTCCCTAGTGTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002841 unedited
  CTCTCCCGCCCGTTGNCGCATAGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCA
  GAGCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGCGAA
  TTCGGCACCAGGGCCCGTGGAGCGGGCGAGCCGGGGAAGCGCCCCGGCTTAGCGGAGGCT
  CGCACGGAGGCAAGAACTTATTCAACAAGTTTACCTCCCTGCTTTCCTCTTTTCGATGTG
  CGTTTTCGGACATGCGGAGGTTACTGGAACCGTGTTGGTGGATTTTGTTCCTGAAAATCA
  CCAGTTCCGTGCTCCATTATGTCGTGTGCTTCCCCGCGTTGACAGAAGGCTACGTTGGGG
  CCCTGCACGAGAATAGACACGGCAGCGCAGTGCAGATCCGCAGGCGCAAGGCTTCAGGCG
  ACCCGTACTGGGCCTACTCTGGTGCCTATGGTCCTGAGCACTGGGTCACGTCTAGTGTCA
  GCTGTGGGGGCCGTCACCAGTCTCCTATTGACATTTTAGACCAGTATGCGCGTGTTGGGG
  AAGAATACCAGGAACTGCAACTCGATGGCTTCGACAATGAGTCTTCTAACAAAACCTGGA
  TGAAAAACACAGGGAAAACAGTCGCCATCCTTCTGAAAGACGACTATTTTGTCAGTGGAG
  CTGGTCTACCTGGCAGATTCAAAGCTGAGAAGGTGGAATTTCACTGGGGCCACAGCAATG
  GCTCAGCGGGCTCTGAACACAGCATCAATGGCAGGAGGTTTCCTGTTGAGATGCAGATTT
  TCTTTTACAATCCAGATGACTTTGACAGCNTTTCAACCGCAATTTCTGAGAACAGAATAA
  TCGGAGCCATGGCATATTTTTTCAGTCAGTCCGAGGGACATTCTGCACTGGATCCTATAT
  CCACGGGTTGAAGGGTGTCGTACTCAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002841 unedited
  CTTGGCCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTAAAGCTGTAATAC
  AGAGTTATCCTTTATTTTGACACATTTTTAAAAAACTGTGAATATAACTTTGTAACTAAT
  AAGGGATGTTCACATGAAGCAGTTCTTAAGCCTTCTAACTTCTTAAGGGATCTCTTAACC
  AGCATAAATGGAACTGTTTCAAGGCCATGACATTAACAGACCTTTTTAGGTCCCAGTAGC
  CTGCTAGTCTGTAAAAGAAAACAATGCTATCCACTCCATTAAAATACAGAAGGCATACAG
  TATTGAACAGTGCCTAAAATAAAAAGGAGAGGAGGACTGAAGAAAAGTACAGCATTGCCT
  GCTAGTAGAATGCAACCACTTCAGCAATAATAATAATAAAAGCAATATTCACTGTCATAA
  CAAAGACCTTCACTGTATTGAACTAAAAAAAAGTAGCATGTATGTCGTCATGGAATGTCA
  CATCAGGGTTTGCTGTTGTATAAGATTATAGGCAGTAACACTGATCATATAGTGCAAACT
  AGGTAAAATTGCGTTTCACTGTGTGAAATGAACAGAGGTGCAAATGCTCAGTAGGATACC
  ATTAAGACATAAAATGGCAAAAAATAAATATCAAAACTTTTATCAGTGTAAAAAAGTCCC
  TGCGCTATTGCATAACCTAGAGCCCGGCACAAAGGCCCCCAACAGGTCCTAGTCCTCACA
  CGTTTACCCCTTAAGTCCCCTTTCCCGATTCCGCCCCCCTAGGCACCCACTGCTCTCAGC
  CCGGGCCCGCTTCCCTCGCTATCACTACCCTCCCACCCTTGTCTCCCGCCCCGGGACCCC
  TCCCCTTTTATTTCGCGCCTCCCCCCCCTACTTCCCCTCCTCCATCCCGGCCCCTCCTCC
  CCCCTCCCCTCCTCTCCCCTCCCCCGCTCCCGCCCTGAATTTTCCCCCTCCGCGCTTTCC
  CCCTCCCCCCTATCGGACCCCCCGCCCCACTCG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_002841
• Insert Size: 3900 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002841.2, NP_002832.2
• RefSeq Size: 5787 bp
• RefSeq ORF: 4338 bp
• Locus ID: 5793
• Cytogenetics: 3p14.2
• Domains: Y_phosphatase, carb_anhydrase, PTPc_motif, FN3
• Protein Families: Druggable Genome, Phosphatase
• Gene Summary: 'The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene. [provided by RefSeq, Jul 2008]'