MEG1 (PTPN4) (NM_002830) Human Untagged Clone

CAT#: SC118395

PTPN4 (untagged)-Human protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) (PTPN4)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PTPN4
• Synonyms: MEG; PTPMEG; PTPMEG1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_002830 edited
  GAATTCGGCACGAGGGTGGACAGTAATGACCTCACGTTTCCGATTGCCTGCTGGCAGAAC
  CTACAATGTACGAGCATCAGAGTTGGCCCGAGACAGACAGCATACTGAAGTGGTTTGCAA
  CATCCTTCTTCTGGATAACACTGTACAAGCTTTCAAAGTCAATAAACATGATCAGGGGCA
  AGTCTTGTTGGATGTCGTCTTCAAGCATCTAGATTTGACTGAGCAGGACTATTTTGGTTT
  ACAGTTGGCTGATGATTCCACAGATAACCCAAGGTGGCTGGATCCAAACAAACCAATAAG
  GAAGCAGCTAAAGAGAGGATCTCCTTACAGTTTGAACTTTAGAGTCAAATTTTTTGTAAG
  TGACCCCAACAAGTTACAAGAAGAATATACAAGGTACCAGTATTTTTTGCAAATTAAACA
  AGACATTCTTACTGGAAGATTACCCTGTCCTTCTAATACTGCTGCCCTTTTAGCTTCATT
  TGCTGTTCAGTCTGAACTTGGAGACTACGATCAGTCAGAGAACTTGTCAGGCTACCTCTC
  AGATTATTCTTTCATTCCTAATCAACCTCAAGATTTTGAAAAAGAAATTGCAAAATTACA
  TCAGCAACACATAGGCTTATCTCCTGCAGAAGCAGAATTTAATTACCTAAACACAGCACG
  TACCTTAGAACTCTATGGAGTTGAATTCCACTATGCAAGGGATCAGAGTAACAATGAAAT
  TATGATTGGAGTGATGTCAGGAGGAATTCTGATTTATAAGAACAGGGTACGAATGAATAC
  CTTTCCATGGTTGAAGATTGTAAAAATTTCTTTTAAGTGCAAACAGTTTTTTATTCAACT
  TAGAAAAGAATTGCATGAATCTAGAGAAACATTATTGGGATTTAATATGGTGAATTACAG
  AGCATGTAAAAATTTGTGGAAAGCATGTGTAGAACATCACACATTCTTCCGTTTGGACAG
  ACCACTTCCACCTCAAAAGAATTTTTTTGCACATTATTTTACATTAGGTTCAAAATTCCG
  GTACTGTGGGAGAACTGAAGTCCAATCAGTTCAGTATGGCAAAGAAAAGGCAAATAAAGA
  CAGGGTATTTGCAAGATCCCCAAGTAAGCCCTTGGCACGGAAATTAATGGATTGGGAAGT
  AGTAAGCAGAAATTCAATATCTGATGACAGGTTAGAAACACAAAGTCTTCCATCACGATC
  TCCACCGGGAACTCCTAATCATCGAAATTCTACATTCACGCAGGAAGGAACCCGGTTACG
  ACCATCTTCAGTTGGTCATTTGGTAGACCATATGGTTCATACTTCCCCAAGCGAAGTGTT
  TGTAAATCAGAGATCTCCGTCATCAACACAAGCTAATAGCATTGTTCTGGAATCATCACC
  ATCACAAGAGACCCCTGGAGATGGGAAGCCTCCAGCTTTACCACCCAAACAGTCAAAGAA
  AAACAGTTGGAACCAAATTCATTATTCACATTCGCAACAAGATCTAGAAAGTCATATTAA
  TGAAACATTTGATATTCCATCTTCTCCTGAAAAACCCACTCCTAATGGTGGTATTCCACA
  TGATAATCTTGTCCTAATCAGAATGAAACCTGATGAAAATGGGAGGTTTGGATTCAATGT
  AAAGGGAGGATATGATCAGAAGATGCCTGTGATTGTGTCTCGAGTAGCACCAGGAACACC
  TGCTGACCTCTGTGTCCCTAGACTGAATGAAGGGGACCAAGTTGTACTGATCAATGGTCG
  GGACATTGCAGAACACACTCATGATCAGGTTGTGCTGTTTATTAAAGCTAGTTGTGAGAG
  ACATTCTGGGGAACTCATGCTTCTAGTTCGACCTAATGCTGTATATGATGTAGTGGAAGA
  AAAGCTAGAAAATGAGCCAGATTTCCAGTATATTCCTGAGAAAGCCCCACTAGATAGTGT
  GCATCAGGATGACCATTCCCTGCGGGAGTCAATGATCCAGCTAGCTGAGGGGCTTATCAC
  TGGAACAGTCCTGACACAGTTTGATCAACTGTATCGGAAAAAACCTGGAATGACAATGTC
  CTGTGCCAAATTACCTCAGAATATTTCCAAAAATAGATACAGAGATATTTCGCCTTATGA
  TGCCACACGGGTCATTTTAAAAGGTAATGAAGACTACATCAATGCGAACTATATAAATAT
  GGAAATTCCTTCTTCCAGCATTATAAATCAGTACATTGCTTGTCAAGGGCCATTACCACA
  CACTTGTACAGATTTTTGGCAGATGACTTGGGAACAAGGCTCCTCTATGGTTGTAATGTT
  GACCACACAAGTTGAACGTGGCAGAGTTAAATGTCACCAATATTGGCCAGAACCCACAGG
  CAGTTCATCTTATGGATGCTACCAAGTTACCTGCCACTCTGAAGAAGGAAACACTGCCTA
  TATCTTCAGGAAGATGACCCTATTTAACCAAGAGAAAAATGAAAGTCGTCCACTCACTCA
  GATCCAGTACATAGCCTGGCCTGACCATGGAGTCCCTGATGATTCGAGTGACTTTCTAGA
  TTTTGTTTGTCATGTACGAAACAAGAGGGCTGGCAAGGAAGAACCCGTTGTTGTCCATTG
  CAGTGCTGGAATCGGAAGAACTGGGGTTCTTATTACTATGGAAACAGCCATGTGTCTCAT
  TGAATGCAATCAGCCAGTTTATCCACTAGATATTGTAAGAACAATGAGAGATCAGCGAGC
  CATGATGATCCAAACACCTAGTCAATACAGATTTGTATGTGAAGCTATTTTGAAAGTTTA
  TGAAGAAGGCTTTGTTAAACCCTTAACAACATCAACAAATAAATAAGAAAGCAAAAAGAT
  CTGGGATATGTGTTGGAAAACTGCTTTCCCTTATGTTCACTGTGCCATAATGCTGCTCGC
  AGGAAATGGCATTTTACAAAAAAAAAAAAAAAAAACTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002830 unedited
  TTTCCCCGCCCGTTGACGCAATGGGCGGTAGGCGTGTACGGTGGGNAGGTCTATATAAGC
  AGAGCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGCGA
  ATTCGGCACGAGGAGGACGCGCTTCTCCTCTGCGCGCCGGGGCCTCGAGGCTTTTTTTCT
  CCAGCCGAGAGGACGCGGCTGTGATATACGAAGACTTTGTGTGGACAGTAATGACCTCAC
  GTTTCCGATTGCCTGCTGGCAGAACCTACAATGTACGAGCATCAGAGTTGGCCCGAGACA
  GACAGCATACTGAAGTGGTTTGCAACATCCTTCTTCTGGATAACACTGTACAAGCTTTCA
  AAGTCAATAAACATGATCAGGGGCAAGTCTTGTTGGATGTCGTCTTCAAGCATCTAGATT
  TGACTGAGCAGGACTATTTTGGTTTACAGTTGGCTGATGATTCCACAGATAACCCAAGGT
  GGCTGGATCCAAACAAACCAATAAGGAAGCAGCTAAAGAGAGGATCTCCTTACAGTTTGA
  ACTTTAGAGTCAAATTTTTTGTAAGTGACCCCAACAAGTTACAGGAAGAATATACAAGGG
  ACCAGTATTTTTTGCAAATTAAACAAGACATTCTTACTGGGAGATTACCCTGTCCTTCTA
  ATACTGCTGCCGTTTTAGCTTCATTTGCTGTTCAGTCCTGAACTTGGAGACTACGAATCA
  GTCACGAGAACTTGGTCAGGGTACTTTTCANATAATTCTTTGATTCCTAATGAGACCTCA
  GAATTGTGGAAGAAGAAATTGCGAAATTACTTCAGCCACGCCTATTTTAAAAGAATTGTC
  CCCCGCGCGGATTGGTATAGAAAGCATTCCCACGCTCCGGGTGCCTTAGCGTGGGAAAGC
  AAATTCGT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002830 unedited
  ATGGACCGGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTGTAAAATGCCAT
  TTCCTGCGAGCAGCATTATGGCACAGTGAACATAAGGGAAAGCAGTTTTCCAACACATAT
  CCCAGATCTTTTTGCTTTCTTATTTATTTGTTGATGTTGTTAAGGGTTTAACAAAGCCTT
  CTTCATAAACTTTCAAAATAGCTTCACATACAAATCTGTATTTGNACTAGGTGTTTGGAT
  CATCATGGCTCGCTGATCTCTCATTGTTCTTACAATATCTAGTGGATAAACTGGCTGATT
  GCATTCAATGAGACACCATGGCTGTTTCCATAGTAATAAGAACCCCAGTTCTTCCGATTC
  CAGCACTGCAATGGACAACAACGGGTTCTTCCTTGCCAGCCCTCTTGTTTCGTACATGAC
  AAACAAAATCTAGAAAGTCACTCGAATCATCAGGGACTCCATGGTCANGCCAGGCTATGT
  ACTGGATCTGAGTGAGTGGACGACTNTCATTTTTCTCTTGGTTAAATANGGTCATCTTCC
  TGAAGATATANGCAGTGTTTCCTTCTCAGAGTGCANGTAACTTGTAGCATCCATAGATGA
  ACTGCCTGTGGGTTCTGGCCAATATGGTGACATTTACTCTGCCACGTCACTTGTGTGGTC
  ACATTACAACATAGNAGACCTTGTCCCAGTCATCTGCAAAATCTGTACAGTGTGTGGTAT
  GGCCTTTGACAGCATGACTGATTATATGGCTGAGAAGATTTCATATTATTTAGTCCATGA
  TGTAGCTCATTACTTTAAAGACCCTGTGCATCTAAGCAATTATTTGATTTTTTGGATATT
  CTAGTATTTGCACAGCATGCATTCAGTTTTTCCATCGTGATCACTGGTAGACTGTTCAGG
  AAACCCTACTACTGACATGCCTCGCGGAATGGTTCTGACCCCTCTAGGGGCTTTAGAATC
  GGATTG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_002830
• Insert Size: 3300 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002830.2, NP_002821.1
• RefSeq Size: 3963 bp
• RefSeq ORF: 2781 bp
• Locus ID: 5775
• Cytogenetics: 2q14.2
• Domains: Y_phosphatase, B41, PDZ, PTPc_motif
• Protein Families: Druggable Genome, Phosphatase
• Gene Summary: 'The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. This PTP has been shown to interact with glutamate receptor delta 2 and epsilon subunits, and is thought to play a role in signalling downstream of the glutamate receptors through tyrosine dephosphorylation. [provided by RefSeq, Jul 2008]'