CXCL7 (PPBP) (NM_002704) Human Untagged Clone

CAT#: SC118473

PPBP (untagged)-Human pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) (PPBP)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PPBP
• Synonyms: B-TG1; Beta-TG; CTAP-III; CTAP3; CTAPIII; CXCL7; LA-PF4; LDGF; MDGF; NAP-2; PBP; SCYB7; TC1; TC2; TGB; TGB1; THBGB; THBGB1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_002704 edited
  ATGAGCCTCAGACTTGATACCACCCCTTCCTGTAACAGTGCGAGACCACTTCATGCCTTG
  CAGGTGCTGCTGCTTCTGTCATTGCTGCTGACTGCTCTGGCTTCCTCCACCAAAGGACAA
  ACTAAGAGAAACTTGGCGAAAGGCAAAGAGGAAAGTCTAGACAGTGACTTGTATGCTGAA
  CTCCGCTGCATGTGTATAAAGACAACCTCTGGAATTCATCCCAAAAACATCCAAAGTTTG
  GAAGTGATCGGGAAAGGAACCCATTGCAACCAAGTCGAAGTGATAGCCACACTGAAGGAT
  GGGAGGAAAATCTGCCTGGACCCAGATGCTCCCAGAATCAAGAAAATTGTACAGAAAAAA
  TTGGCAGGTGATGAATCTGCTGATTAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002704 unedited
  NCCCGTTCAGATTTTGTATACGACTCACTATAGGCGGCCGCGAATCGGCACGAGCTCTAG
  CTCATCCTTCTCCACCATGAGCCTCAGACTTGATACCACCCCTTCCTGTAACAGTGCGAG
  ACCACTTCATGCCTTGCAGGTGCTGCTGCTTCTGTCATTGCTGCTGACTGCTCTGGCTTC
  CTCCACCAAAGGACAAACTAAGAGAAACTTGGCGAAAGGCAAAGAGGAAAGTCTAGACAG
  TGACTTGTATGCTGAACTCCGCTGCATGTGTATAAAGACAACCTCTGGAATTCATCCCAA
  AAACATCCAAAGTTTGGAAGTGATCGGGAAAGGAACCCATTGCAACCAAGTCGAAGTGAT
  AGCCACACTGAAGGATGGGAGGAAAATCTGCCTGGACCCAGATGCTCCCAGAATCAAGAA
  AATTGTACAGAAAAAATTGGCAGGTGATGAATCTGCTGATTAATTTGTTCTGTTTCTGCC
  AAACTTCTTTAACTCCCAGGAAGGGTAGAATTTTGAAACCTTGATTTTCTAGAGTTCTCA
  TTTATTCAGGATACCTATTCTTACTGTATTAAAATTTGGATATGTGTTTCATTCTGTCTC
  AAAAATCACATTTTATTCTGAGAAGGTTGGTTAAAAGATGGCAGAAAGAAGATGAAAATA
  AATAAGCCTGGTTTCAACCCTCTAATTCTTGCCTAAACATTGGACTGTACTTTGCATTNT
  TTTCTTTAAAAATTTCTATTCTAACACAACTTGGTTGATTNTTCCTGGTCTACTNTATGG
  NTATTAGACATACTCATGGGTATTATTAGATTTCATAATGGTCAATGATAATAGGAAATA
  CATGGAGCCCCACAGAGATATTGCTCATACATTTTTGTTATATATTCTAGACTCATGGAG
  CCTCTCGTG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_002704
• Insert Size: 1750 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002704.2, NP_002695.1
• RefSeq Size: 715 bp
• RefSeq ORF: 387 bp
• Locus ID: 5473
• Cytogenetics: 4q13.3
• Domains: IL8
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: Chemokine signaling pathway, Cytokine-cytokine receptor interaction
• Gene Summary: 'The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. The protein also is an antimicrobial protein with bactericidal and antifungal activity. [provided by RefSeq, Nov 2014]'