LOX 1 (OLR1) (NM_002543) Human Untagged Clone

CAT#: SC118589

OLR1 (untagged)-Human oxidized low density lipoprotein (lectin-like) receptor 1 (OLR1), transcript variant 1


  "NM_002543" in other vectors (7)

Reconstitution Protocol

USD 660.00

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol OLR1
Synonyms CLEC8A; LOX1; LOXIN; SCARE1; SLOX1
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC118589 sequence for NM_002543 edited (data generated by NextGen Sequencing)
ATGACTTTTGATGACCTAAAGATCCAGACTGTGAAGGACCAGCCTGATGAGAAGTCAAAT
GGAAAAAAAGCTAAAGGTCTTCAGTTTCTTTACTCTCCATGGTGGTGCCTGGCTGCTGCG
ACTCTAGGGGTCCTTTGCCTGGGATTAGTAGTGACCATTATGGTGCTGGGCATGCAATTA
TCCCAGGTGTCTGACCTCCTAACACAAGAGCAAGCAAACCTAACTCACCAGAAAAAGAAA
CTGGAGGGACAGATCTCAGCCCGGCAACAAGCAGAAGAAGCTTCACAGGAGTCAGAAAAC
GAACTCAAGGAAATGATAGAAACCCTTGCTCGGAAGCTGAATGAGAAATCCAAAGAGCAA
ATGGAACTTCACCACCAGAATCTGAATCTCCAAGAAACACTGAAGAGAGTAGCAAATTGT
TCAGCTCCTTGTCCGCAAGACTGGATCTGGCATGGAGAAAACTGTTACCTATTTTCCTCG
GGCTCATTTAACTGGGAAAAGAGCCAAGAGAAGTGCTTGTCTTTGGATGCCAAGTTGCTG
AAAATTAATAGCACAGCTGATCTGGACTTCATCCAGCAAGCAATTTCCTATTCCAGTTTT
CCATTCTGGATGGGGCTGTCTCGGAGGAACCCCAGCTACCCATGGCTCTGGGAGGACGGT
TCTCCTTTGATGCCCCACTTATTTAGAGTCCGAGGCGCTGTCTCCCAGACATACCCTTCA
GGTACCTGTGCATATATACAACGAGGAGCTGTTTATGCGGAAAACTGCATTTTAGCTGCC
TTCAGTATATGTCAGAAGAAGGCAAACCTAAGAGCACAGTGA

Clone variation with respect to NM_002543.3
>OriGene 5' read for NM_002543 unedited
NGTTCGGGATTTTGTAATACGACTTACTATAGGCGGCCGCGNAATTCGCACGAGGCTGCT
TCACTCTCTCATTCTTAGCTTGAATTTGGAAATGACTTTTGATGACCTAAAGATCCAGAC
TGTGAAGGACCAGCCTGATGAGAAGTCAAATGGGAAAAAAAGCTAAAGGTCTTCAGTTTC
TTTACTCTCCATGGTGGTGCCTGGCTGCTGCGACTCTAGGGGTCCTTTGCCTGGGATTAG
TAGTGACCATTATGGTGCTGGGCATGCAATTATCCCAGGTGTCTGACCTCCTAACACAAG
AGCAAGCAAACCTAACTCACCAGAAAAAGAAACTGGAGGGACAGATCTCAGCCCGGCAAC
AAGCAGAAGAAGCTTCACAGGAGTCAGAAAACGAACTCAAGGAAATGATAGAAACCCTTG
CTCGGAAGCTGAATGAGAAATCCAAAGAGCAAATGGAACTTCACCACCAGAATCTGAATC
TCCAAGAAACACTGAAGAGAGTAGCAAATTGTTCAGCTCCTTGTCCGCAAGACTGGATCT
GGCATGGAGAAAACTGTTACCTATTTTCCTCGGGCTCATTTAACTGGGAAAAGAGCCAAG
AGAAGTGCTTGTCTTTGGATGCCAAGTTGCTGAAAATTAATAGCACAGCTGATCTGGACT
TCATCCAGCAAGCAATTTCCTATTCCAGTTTTCCATTCTGGATGGGGCTGTCTCGGAGGA
ACCCCAGCTACCCATGGCTCTGGGAGGACGGTTCTCCTTTGATGCCCCACTTATTAGAGT
CCGAGGCGCTGTCTNCCCAAAATACCCTTCAGGTACCTGTGCATATATACAACGAGGAGC
TGTTTATGCCGAAAACTGCCATTTAGCTGCCTTCAGTATATGTCAGAAAGAGGCNANACC
TAGNAGCCCAGTGATTT
>OriGene 3' read for NM_002543 unedited
ACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTGGACCCAAATGTTCACAACAGCTTTTTTTGTAATATCCCAAAACTAA
AACAACCCCAATGTCCTCAACAAGTAAATGGGGAAAAGAATTGGGGGTTTTCCCTACCAG
GGAATATTCAACATTTAAAAAAATGAATTCCTTCCACCCTTAAAATGGGGACCTTTGAAT
CTCAAAATAATTATGCCAAGGGAAAAAAGCCCCACCAAAAAAAAAAACCTTCTTTTTGAT
TCCCTTCCCCTAAAACTTCCAAATGCCAAATGAAAGCCCATTGGGGGGTTTTTGGGGGGG
AGTCCTCAGGAGGAGCCTTGGGACCCTTTGAGGGATGAAGGATATGTTCACTCTCTTAAT
TGGAGGATGCATGTTCTCCACAAGGGGGGAAAACTTATCAAATAGTACACTTTAAATATG
TTCAGGTTATTTTATGGTAATTATATCTCAATAAAGCTTTTAACAAAAGCAAACATTTTT
TGCCTACATAAGGATGACACAACTCTTAAAAAAAAAAAAAAAATTTCTGCTATATTGGGT
GCACCAAAATAAAAAGGGTTCCCTTAAAGTAAAAAACCCCGTGGAGAATGGGTGGAAAGG
AATAAAAACCCTAAAAATAAAAAAAATATTTCTAAATCCCTCTGGTTTTTATTAACCGAA
TTTGCCTACCTGCCTCAATTTGTCTAAAAGGAGGGCCTCCTTTTTTTTTGCCTGGAAGGT
GCCGAATTTTACCTACCCAACCAAGTTGGAAAATCTCTTCTCCAAGGTGTTTTTTTTAGG
GAAAAAATTTATTTTACCTTTGGGCCCACATCCATGTTTTAACAAAATGTGGGAAGGGGT
AAACCTTAAATTGCCCTCGGAGAAAAAAAAGAG
Restriction Sites NotI-NotI     
ACCN NM_002543
Insert Size 2600 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_002543.2, NP_002534.1
RefSeq Size 2476 bp
RefSeq ORF 822 bp
Locus ID 4973
Cytogenetics 12p13.2
Domains CLECT
Protein Families Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways PPAR signaling pathway
Gene Summary 'This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]'
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).

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