MSX2 (NM_002449) Human Untagged Clone

CAT#: SC118633

MSX2 (untagged)-Human msh homeobox 2 (MSX2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MSX2
• Synonyms: CRS2; FPP; HOX8; MSH; PFM; PFM1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_002449, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCTTCTCCGTCCAAAGGCAATGACTTGTTTTCGCCCGACGAGGAGGGCCCAGCAGTGGTGGCCGGAC
  CAGGCCCGGGGCCTGGGGGCGCCGAGGGGGCCGCGGAGGAGCGCCGCGTCAAGGTCTCCAGCCTGCCCTT
  CAGCGTGGAGGCGCTCATGTCCGACAAGAAGCCGCCCAAGGAGGCGTCCCCGCTGCCGGCCGAAAGCGCC
  TCGGCCGGGGCCACCCTGCGGCCACTGCTGCTGTCGGGGCACGGCGCTCGGGAAGCGCACAGCCCCGGGC
  CGCTGGTGAAGCCCTTCGAGACCGCCTCGGTCAAGTCGGAAAATTCAGAAGATGGAGCGGCGTGGATGCA
  GGAACCCGGCCGATATTCGCCGCCGCCAAGACATATGAGCCCTACCACCTGCACCCTGAGGAAACACAAG
  ACCAATCGGAAGCCGCGCACGCCCTTTACCACATCCCAGCTCCTCGCCCTGGAGCGCAAGTTCCGTCAGA
  AACAGTACCTCTCCATTGCAGAGCGTGCAGAGTTCTCCAGCTCTCTGAACCTCACAGAGACCCAGGTCAA
  AATCTGGTTCCAGAACCGAAGGGCCAAGGCGAAAAGACTGCAGGAGGCAGAACTGGAAAAGCTGAAAATG
  GCTGCAAAACCTATGCTGCCCTCCAGCTTCAGTCTCCCTTTCCCCATCAGCTCGCCCCTGCAGGCAGCGT
  CCATATATGGAGCATCCTACCCGTTCCATAGACCTGTGCTTCCCATCCCGCCTGTGGGACTCTATGCCAC
  GCCAGTGGGATATGGCATGTACCACCTGTCCTAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002449 unedited
  TCGGCATTTGTATACGACTACTATAGGGCGGCCGCGATTCGGCACGATTTGCCAGCGGAG
  TCGCGCGTCGGGAGCTACGTAGGGCAGAGAAGTATGGCTTCTCCGTCCAAAGCAATGACT
  TGTTTTCGCCCGACGAGGAGGGCCCATCAGTGGTGGCCGGACCAGGCCCGGGGCCTGGGG
  GCGCCGAGGGGGCCGCGGAGGATCGCCGCGTCAAGGTCTCCAGCCTGCCCTTCATCGTGG
  AGGCGCTCATGTCCGACAAGAATCCGCCCAATGATGCGTCCCCGCTGCCGGCCGAAAGCG
  CCTCGGCCGGGGCCACCCTGCGGCCACTGCTGCTGTCGGGGCACGGCGCTCGGGAAGCGC
  ACAGCCCCGGGCCGCTGGTGAAGCCCTTCGAGACCGCCTCGGTCAAGTCGGAAAATTCAT
  AATATGGAGCGGCGTGGATGCATGAACCCGGCCGATATTCGCCGCCGCCAAGACATACGA
  TCCCTACCACCTGCACCCTGATGAAACACAAGACCAATCGGAAGCCGCGCACGCCCTTTA
  CCACATCCCATCTCCTCGCCCTGGAGCGCAAGTTCCGTCAGAAACAGTACCTCTCCATTG
  CAGATCGTGCAGAGTTCTCCAGCTCTCTGAACCTCACAGATACCCATGTCAAAATCTGGT
  TCCAGAACCGAATGGCCAATGCGAATAGACTGCANGATGCAGAACTGGAATAGCTGATAA
  TGGCTGCATAACCTATGCTGCCCTTCAGCTTCAGTCTCCCTTTNCCCATCATCTCGCCCC
  TGCAGGCAGCGTNCATATATGGAGCATCCTACCCGTTCATAGACCTGTGCTTNCCATCCG
  NNCTGTGGACTCTATGCACGCAGTNGGTATGGCATGTACAACCTGTCTAAGGAGACAGAT
  CATAGACTCCTGATGATGCTTGTTAAGGNNTNCTTTCTCTCAGAAGCATACAGCATACTC
  TGCTTGTACCTGGTGACCACTN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002449 unedited
  ACGTACACTATGNACGCGGCCGCAATCTATGATCGGTTTTTTTTTTTTTTTTTTGAGTTT
  GGACAAACTTTACTGCAATAAAACAAATGCTTAATTTAATTCAGAATAAGAGATAACTCT
  TCAATAAAATATATCAAATTGTACAAGCACCCTTTCAAAGGGATAAAGGTATACCGGAGG
  GAGGGGAGAGATGGACAGGAAGGTGAAATACCAGGGAGCTTAATGGGCTGTTTGACAACC
  CCATTTTCACCAAGTCAAAACATGGCTTTACCTTCTGCCCCCCCAACATGTAAAAAAGTA
  TATAAAATTTTCTAATAAGTTTAGGACATACAACAGGTACACACACAGAGAAAGCATATT
  TTTTTTTTCTTTCTGGATCTACTAATTGTTCAAGAATATTTAGCATATAGGTAATGGTTA
  CAAGATACTCATTTTTTAAGCAGAAAATTACTAAACCCCCACCCAAATCACCTTTGCAAT
  CTGTGAGGATGAATGTACCTAGTATTTCTCAGAAACCATCAATTCCTCTCAACAGGTTTT
  AACATTTTACTCTCCAATTATCTGAAATAAAGTTACCAACAGCCTTGAGAAGATTAAGGA
  GTATTTCTAATTTTCTACCTCACCTTCAGGCAGTCTCAAGATTCTTCTCATCCCAAGTAT
  GGTCTTACAAAATATTCTTAAAAAAGAAAAACTTTAAAATTATNTTTGGTGGGGCGGTGG
  GGGGCGGGGGAAAAATAAGAACAACTGGGGTATTAAAGAGGGTTCTTTTATGCCAGGAAA
  TGCCGAAATTTGAGGGGCCCCCCTCCTTGGATAAACCCCCCAAACTAAAATTTTCGGGGG
  GCCAGGGGCTGGTTTTTGGTTTCCCTA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_002449
• Insert Size: 2250 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002449.3, NP_002440.2
• RefSeq Size: 2224 bp
• RefSeq ORF: 804 bp
• Locus ID: 4488
• Cytogenetics: 5q35.2
• Domains: homeobox
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: 'This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (1) encodes the longer isoform (1).