MMP15 (NM_002428) Human Untagged Clone

CAT#: SC118648

MMP15 (untagged)-Human matrix metallopeptidase 15 (membrane-inserted) (MMP15)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MMP15
• Synonyms: MMP-15; MT2-MMP; MT2MMP; MTMMP2; SMCP-2
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_002428 edited
  GAATTCGGCACGAGGGGCGCGCCTGCCGGGCCAGGAGCCAGGGAGCGTCGCAAGTTTCCA
  AGGCGCGTGCGAGGATCCGGCGTGCAGTGTTCCGAGCTGGGCTGGGCGCCGAGAGCATGG
  GCAGCGACCCGAGCGCGCCCGGACGGCCGGGCTGGACGGGCAGCCTCCTCGGCGACCGGG
  AGGAGGCGGCGCGGCCGCGACTGCTGCCGCTGCTCCTGGTGCTTCTGGGCTGCCTGGGCC
  TTGGCGTAGCGGCCGAAGACGCGGAGGTCCATGCCGAGAACTGGCTGCGGCTTTATGGCT
  ACCTGCCTCAGCCCAGCCGCCATATGTCCACCATGCGTTCCGCCCAGATCTTGGCCTCGG
  CCCTTGCAGAGATGCAGCGCTTCTACGGGATCCCAGTCACCGGTGTGCTCGACGAAGAGA
  CCAAGGAGTGGATGAAGCGGCCCCGCTGTGGGGTGCCAGACCAGTTCGGGGTACGAGTGA
  AAGCCAACCTGCGGCGGCGTCGGAAGCGCTACGCCCTCACCGGGAGGAAGTGGAACAACC
  ACCATCTGACCTTTAGCATCCAGAACTACACGGAGAAGTTGGGCTGGTACCACTCGATGG
  AGGCGGTGCGCAGGGCCTTCCGCGTGTGGGAGCAGGCCACGCCCCTGGTCTTCCAGGAGG
  TGCCCTATGAGGACATCCGGCTGCGGCGACAGAAGGAGGCCGACATCATGGTACTCTTTG
  CCTCTGGCTTCCACGGCGACAGCTCGCCGTTTGATGGCACCGGTGGCTTTCTGGCCCACG
  CCTATTTCCCTGGCCCCGGCCTAGGCGGGGACACCCATTTTGACGCAGATGAGCCCTGGA
  CCTTCTCCAGCACTGACCTGCATGGAAACAACCTCTTCCTGGTGGCAGTGCATGAGCTGG
  GCCACGCGCTGGGGCTGGAGCACTCCAGCAACCCCAATGCCATCATGGCGCCGTTCTACC
  AGTGGAAGGACGTTGACAACTTCAAGCTGCCCGAGGACGATCTCCGTGGCATCCAGCAGC
  TCTACGGTACCCCAGACGGTCAGCCACAGCCTACCCAGCCTCTCCCCACTGTGACGCCAC
  GGCGGCCAGGCCGGCCTGACCACCGGCCGCCCCGGCCTCCCCAGCCACCACCCCCAGGTG
  GGAAGCCAGAGCGGCCCCCAAAGCCGGGCCCCCCAGTCCAGCCCCGAGCCACAGAGCGGC
  CCGACCAGTATGGCCCCAACATCTGCGACGGGGACTTTGACACAGTGGCCATGCTTCGCG
  GGGAGATGTTCGTGTTCAAGGGCCGCTGGTTCTGGCGAGTCCGGCACAACCGCGTCCTGG
  ACAACTATCCCATGCCCATCGGGCACTTCTGGCGTGGTCTGCCCGGTGACATCAGTGCTG
  CCTACGAGCGCCAAGACGGTCGTTTTGTCTTTTTCAAAGGTGACCGCTACTGGCTCTTTC
  GAGAAGCGAACCTGGAGCCCGGCTACCCACAGCCGCTGACCAGCTATGGCCTGGGCATCC
  CCTATGACCGCATTGACACGGCCATCTGGTGGGAGCCCACAGGCCACACCTTCTTCTTCC
  AAGAGGACAGGTACTGGCGCTTCAACGAGGAGACACAGCGTGGAGACCCTGGGTACCCCA
  AGCCCATCAGTGTCTGGCAGGGGATCCCTGCCTCCCCTAAAGGGGCCTTCCTGAGCAATG
  ACGCAGCCTACACCTACTTCTACAAGGGCACCAAATACTGGAAATTCGACAATGAGCGCC
  TGCGGATGGAGCCCGGCTACCCCAAGTCCATCCTGCGGGACTTCATGGGCTGCCAGGAGC
  ACGTGGAGCCAGGCCCCCGATGGCCCGACGTGGCCCGGCCGCCCTTCAACCCCCACGGGG
  GTGCAGAGCCCGGGGCGGACAGCGCAGAGGGCGACGTGGGGGATGGGGATGGGGACTTTG
  GGGCCGGGGTCAACAAGGACAGGGGCAGCCGCGTGGTGGTGCAGATGGAGGAGGTGGCAC
  GGACGGTGAACGTGGTGATGGTGCTGGTGCCACTGCTGCTGCTGCTCTGCGTCCTGGGCC
  TCACCTACGCGCTGGTGCAGATGCAGCGCAAGGGTGCGCCACGTGTCCTGCTTTACTGCA
  AGCGCTCGCTGCAGGAGTGGGTCTGACCACCCAGCGCTCCTGCTAACGGTGCTCAGGGGG
  CGCCTGTGGTTCTGAGATGGCTCCCAGGGGCTCCCTCCGCCCCCAGGTAGGGGCCCCTCT
  CAGCCCTCACACACCCTGTCTGCCCCGCCCTCATTATTTATGTCCAGGTGTTTGTTTTGT
  TTTGTTTTTGGCACCTTACTTGACCATTTGTTTCTGTTTCCCCGACTGGGGCAGGGTGTT
  TAGAATTTTCTAAATGTAGTTCTGCTCCAGACAGGGAATTAGGCCCTCATCATCCTCTGG
  CTTGGCCACAGCCAGGGGAGCAGAGGGGCAGAGGCCCACATTGGAAGAGCAGCACCTCCT
  CAGCCTGAACCCCAGGGCTGTAACTGCCAGGCTCTCTTTGCCCAGTTGGAGACTGTCTGG
  CCCCCCTGGTCCCCTCCTTCCCAAGTGAGTCTCTCTGGGCCTTAGGAAGAGCCTTCCACC
  CAGGGGCAGCCCCAGGCCAAAGGGGACCTGGAAGGGAGGTGGGCCGTGGCCCTTGAGTCC
  CCATTGAGGCTTGGTTCCTTCCCAATCCAGTGGACTTCGCAGTCCACTTCTGACAGCCTC
  AGTGACCCTGGCTCCTTGTGCCAGAGAACCCAGCCCACCCCCGGCAGCAGCCCCCAGCTC
  CCACCTCCCCTTGGGCCCACACCTCCTTCCCTCTCTGGAGAAAGGGCCCTGGGCCTGCCT
  CACCACGGACCAAAGGGAGTCTGCCAGGGCCCCTCTCCCCAGGGAAGCAGCAGCCTCGCC
  CCTGGCAGAGATGCCTCCCTGAGCTAGAACCCTCTGTTCCTTCCCTGTGCCTCCTCCCTC
  CCTCTCGACTCACACCACTAGCCTCAGGGGTCTGAGCTCCAGCTCCTTTCGGCTTCAGCT
  GCCAGTGTCCTGAGCCCCAGGGAGAGGGGGCTGGTGGGTGCCTAGGCCTGGGCAGTGGAT
  GGCCGTGAATGGGTGCCCACAGTGTCAGGCACTGGGCATGAGGGGTTCCTCCCCTCCAGC
  TCCCTGTGCCCCCAGGGTCCTGGGAGGAGAGACACTGGTGGGGATAGGCCAGCCGCGCAT
  CAGACTGTGAACCCCACGAAGGAGCCCATTGTGGCCTAAGAGGCTGCCCTCCTGTGCTCA
  GCCCTGAGGACAGATGCCTCCTTCCTCTTTTCCTTCCCAAAGCAAGCAAGAGGCCGTGGC
  TGCTGTGGGAAATGGTACTGTACAGCTGGCTCTACTTCCCCATGGCCCTGAGCGAGTGGA
  GTCTGCCACCCAGGATCCCCAAGGCACTTGAGGGGGAAGGATTCTGCTGGCCTCTGCGAG
  TGGTTTCTTGTGCACTGGCACCAAGTGCGGGTCCGGCAGCTTCTGCCCCCTGCAGAACCG
  GAGAGCCAGCTAAGGGGTGGGGCTGCGGGGGTTCCGTGTCCACCCCCATACATTTATTTC
  TGTAAATAATGTGCACTGAATAAATTGTACAGCCGGCAAAAAAAAAAAAAAAAAACTCGA
  C
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002428 unedited
  NNTTTTTTNNTATTTCCCGCCCGTTGCCGCAATGGGCGGTAGGCGTGTACGGTGGGAGGT
  CTATATAAGCAGAACTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGC
  AGCGGCCGCGAATTCGGCACGAGGGGCGCGCCTGCCGGGCCAGGAGCCAGGGAGCGTCGC
  AAGTTTCCAAGGCGCGTGCGAGGATCCGGCGTGCAGTGTTCCGAGCTGGGCTGGGCGCCG
  AGAGCATGGGCAGCGACCCGAGCGCGCCCGGACGGCCGGGCTGGACGGGCAGCCTCCTCG
  GCGACCCGGAAGAAGCGGCGCGGCCGCGACTGCTGCCGCTGCTCCTGGTGCTTCTGGGCT
  GCCTGGGCCTTGGCGTANNCCGCCGAAAACGCCCGAGTCCATGCCGAGGACTGGCTGCGG
  CTTTATGGCTAACTGGCTTAGGCAGGCGGCATATGTTCACCATGCGTTTCCGGCAGATTC
  TGGCCTCGGCCCTTGCANAGATGCAGCGCTTCTACCGGATCCCAGTCAACGGTGTGCTCG
  ACCAANAGACAAAGAGTGGATGAAACGCCCCCCTTTGGGGTGTCAGACCAATTCGGGGTA
  CCAATGAGAGCCCAACTGTGGGGCGTCTGAAACGCTATGCGCTCTACGGGAGGAAATGGA
  CAACCCCCATCTTGACCTTAGCATCCCGAAATACACCGAGGAATTTGGCTGGGACCCCTC
  CATGGAGCCGTGGCGCAGGGCTTTCCCGTGTGGGACACAGCACAGCCCCTGGTCTTTCCG
  GAGAGCCCCTATAGAGGATTCCGGTTGCGGCAACGAAGGAGCCAACTTCGGAAACCCTTG
  GCTCTGGCTCCACGCGACGCCTCGCCGTTGATG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002428 unedited
  TTTTAAATTAATTACGTGNANCGCGGCCGCATTCNANGATCGNGTTTTTTTTTTTTTTTT
  TTGCCGGCTGTACAATTTATTCAGTGCACATTATTTACAGAAATAAATGTATGGGGGTGG
  ACACGGAACCCCCGCAGCCCCACCCCTTAGCTGGCTCTCCGGTTCTGCAGGGGGCAGAAG
  CTGCCGGACCCGCACTTGGTGCCAGTGCACAAGAAACCACTCGCAGAGGCCAGCAGAATC
  CTTCCCCCTCAAGTGCCTTGGGGATCCTGGGTGGCAGACTCCACTCGCTCAGGGCCATGG
  GGAAGTAGAGCCCGCTGTACAGTACCATTTCCCACAACACCACGGGCTTTTGTTTGTTTG
  GGAAGGGAAAGAGGAAGGGGGCTTTTGCCCTAGGGCTAGACCCGGAGGGCCCCCTTTTTA
  GGCCCAAGGGGGCTCCTTTGGGGGGTAAAAATTTGGGGGCCGGGGGGGGCTTATCCCCCA
  CAGGGTTTTTCCCCCCCAACCCCCCGGGGGCCCAAAGGGTTGGGGGGGGGGGAAAACCCC
  TTGTTCCCCCGGGTGGTAATTTTGGGGGGGGCCCCTTTTTGTGGGGGCCCCCTTCGGTGG
  GGGGGGTGGAGGCCCCCCCCCCCCCCCCCCCTCTCTTTTGGGGGGGGAAACACACAAAGG
  GGTTGGGGAAAAAAAAAAGAGAGGGGGTCTCCCCCCCCCCCCCCCCCCTTTTTTTTTTTT
  TGTTTTTTTGCGGCCGGGGGGGGGGGGGCCCCCCCCAAAAAAAAAAAAATCTTTATTTTT
  TTCTGTTGGGGGTGCCTGCCTTCTCTCCCCGGGGGGGGGGTTTTTTTTTTTTTTTATGGA
  GAGGGGAAAGGGGGGAGGTCTTCTCTTTTTTTTTGGGGGGTTGGGGGGGGGAGGAGGGTT
  CCTCTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_002428
• Insert Size: 3600 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002428.2, NP_002419.1
• RefSeq Size: 4456 bp
• RefSeq ORF: 2010 bp
• Locus ID: 4324
• Cytogenetics: 16q21
• Domains: hemopexin, Peptidase_M10, ZnMc
• Protein Families: Druggable Genome, Protease, Transmembrane
• Gene Summary: 'This gene encodes a member of the peptidase M10 family and membrane-type subfamily of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Members of this subfamily contain a transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. The encoded preproprotein is proteolytically processed to generate the mature protease. This protein may play a role in cancer progression. [provided by RefSeq, Jan 2016]'