LOX (NM_002317) Human Untagged Clone

CAT#: SC118674

LOX (untagged)-Human lysyl oxidase (LOX), transcript variant 1


  "NM_002317" in other vectors (6)

Reconstitution Protocol

USD 310.00

In Stock*

Size
    • 10 ug

Product Images

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol LOX
Synonyms AAT10
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC118674 sequence for NM_002317 edited (data generated by NextGen Sequencing)
ATGCGCTTCGCCTGGACCGTGCTCCTGCTCGGGCCTTTGCAGCTCTGCGCGCTAGTGCAC
TGCGCCCCTCCCGCCGCCGGCCAACAGCAGCCCCCGCGCGAGCCGCCGGCGGCTCCGGGC
GCCTGGCGCCAGCAGATCCAATGGGAGAACAACGGGCAGGTGTTCAGCTTGCTGAGCCTG
GGCTCACAGTACCAGCCTCAGCGCCGCCGGGACCCGGGCGCCGCCGTCCCTGGTGCAGCC
AACGCCTCCGCCCAGCAGCCCCGCACTCCGATCCTGCTGATCCGCGACAACCGCACCGCC
GCGGCGCGAACGCGGACGGCCGGCTCATCTGGAGTCACCGCTGGCCGCCCCAGGCCCACC
GCCCGTCACTGGTTCCAAGCTGGCTACTCGACATCTAGAGCCCGCGAAGCTGGCGCCTCG
CGCGCGGAGAACCAGACAGCGCCGGGAGAAGTTCCTGCGCTCAGTAACCTGCGGCCGCCC
AGCCGCGTGGACGGCATGGTGGGCGACGACCCTTACAACCCCTACAAGTACTCTGACGAC
AACCCTTATTACAACTACTACGATACTTATGAAAGGCCCAGACCTGGGGGCAGGTACCGG
CCCGGATACGGCACTGGCTACTTCCAGTACGGTCTCCCAGACCTGGTGGCCGACCCCTAC
TACATCCAGGCGTCCACGTACGTGCAGAAGATGTCCATGTACAACCTGAGATGCGCGGCG
GAGGAAAACTGTCTGGCCAGTACAGCATACAGGGCAGATGTCAGAGATTATGATCACAGG
GTGCTGCTCAGATTTCCCCAAAGAGTGAAAAACCAAGGGACATCAGATTTCTTACCCAGC
CGACCAAGATATTCCTGGGAATGGCACAGTTGTCATCAACATTACCACAGTATGGATGAG
TTTAGCCACTATGACCTGCTTGATGCCAACACCCAGAGGAGAGTGGCTGAAGGCCACAAA
GCAAGTTTCTGTCTTGAAGACACATCCTGTGACTATGGCTACCACAGGCGATTTGCATGT
ACTGCACACACACAGGGATTGAGTCCTGGCTGTTATGATACCTATGGTGCAGACATAGAC
TGCCAGTGGATTGATATTACAGATGTAAAACCTGGAAACTATATCCTAAAGGTCAGTGTA
AACCCCAGCTACCTGGTTCCTGAATCTGACTATACCAACAATGTTGTGCGCTGTGACATT
CGCTACACAGGACATCATGCGTATGCCTCAGGCTGCACAATTTCACCGTATTAG

Clone variation with respect to NM_002317.5
>OriGene 5' read for NM_002317 unedited
GTCAGATTTGTAAACGACTTCACTATAGGCGGCCCGCGAATTCGCACGAGGCAGACACTG
CCCGCTCTCCGGGACTGCCGCGCCGCTCCCCGTTGCCTTCCAGGACTGAGAAAGGGGAAA
GGGAAGGGTGCCACGTCCGAGCAGCCGCCTTGACTGGGGAAGGGTCTGAATCCCACCCTT
GGCATTGCTTGGTGGAGACTGAGATACCCGTGCTCCGCTCGCCTCCTTGGTTGAAGATTT
CTCCTTCCCTCACGTGATTTGAGCCCCGTTTTTATTTTCTGTGAGCCACGTCCTCCTCGA
GCGGGGTCAATCTGGCAAAAGGAGTGATGCGCTTCGCCTGGACCGTGCTCCTGCTCGGGC
CTTTGCAGCTCTGCGCGCTAGTGCACTGCGCCCCTCCCGCCGCCGGCCAACAGCAGCCCC
CGCGCGAGCCGCCGGCGGCTCCGGGCGCCTGGCGCCAGCAGATCCAATGGGAGAACAACG
GGCAGGTGTTCAGCTTGCTGAGCCTGNGCTCACAGTACCAGCCTCAGCGCCGCCGGGACC
CGGGCGCCGCCGTCCCTGGTGCAGCCAACGCCTCCGCCCAGCAGCCCCGCACTCCGATCC
TGCTGATCCGCGACAACCGCACCGCCGCGGCGCGAACGCGGACGGCCGGCTCATCTGGAG
TCACCGCTGGCCGCCCCAGGCCCACCGCCCGTCACTGGTTCCAAGCTGCCTACTCGACAT
CTAGAGCCCCGCGAAGCTGGCGCCTCGCGCGCCGGAGACCAGACAGCGCCCGGGAGAAGT
TCCTGCGCTCAGTAACCCGCGGCCGCCCAACCGCGTGGACGGCATGTTGGGCCGACGACC
CTTACAACCCCTACAAGTACTCTTGACGACAACCCTTTTATACCACTTACTACGATACTC
ATTGAAAGGCCCCAACCTGGGGGCCAGTCCCCGGCCCG
>OriGene 3' read for NM_002317 unedited
GGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGAAAGATCAAATATGTAATTAC
AGAATTGAAACACTGTGTTAATTCACAAAGTGATGTAAATAATAAACATTAAAAATTTCC
CAAGTAATGATGACTTAAGCGTTCAAAATCCAGTTATGTGCTTTGTTATTGAAAACAGTC
CAAACAAAAATTCTTTTGTTGTTTTCTGTTCTCTTTTTCAAAATACATAAATCCTACTGA
AGTTAGTCTATTTTTTCCCACTTCAGAACACCAGGCACTGATTTATCCATTGGGAGTTTT
GCTTTGCCTTCTAATACGGTGAAATTGTGCAGCCTGAGGCATACGCATGATGTCCTGTGT
AGCGAATGTCACAGCGCACAACATTGTTGGTATAGTCAGATTCAGGAACCAGGTAGCTGG
GGTTTACACTGACCTTTAGGATATAGTTTCCAGGTTTTACATCTGTAATATCAATCCACT
GGCAGTCTATGTCTGCACCATAGGTATCATAACAGCCAGGACTCAATCCCTGTGTGTGTG
CAGTACATGCAAATCGCCTGTGGTAGCCATAGTCACAGGATGTGTCTTCAAGACAGAAAC
TTGCTCTGTGGCCTTCAGCCACTCTCCTCTGGGTGTTGGCATCAAGCAGGTCATAGTGGC
TAAACTCATCCATACTGTGGTAATGCTGATGACAACTGTGCCATTCCCAGGAATATCTTG
GTCGGCTGGGTAAGACATCTGATGTCCCTTGGTTTTTCACTCTTTGGGGAAATCTGAGCA
GCACCCTGTGATCATAATCTCTGACATCTGGCCTGTATGCTGTACTGGCCAGACAAGTTT
TCTCCGCCGCGCATCTCAAGTTGACATGGACATCTTCTGACGTACGTGAACGCCTGGTGT
ATTAGGGGTCGCCCCCAGGCTGGGAAACCGCACTGGAAGTACCAGGCCGTATTCGGGCCG
CACCTGCCCCCAGCTG
Restriction Sites NotI-NotI     
ACCN NM_002317
Insert Size 1870 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_002317.3, NP_002308.2
RefSeq Size 1946 bp
RefSeq ORF 1254 bp
Locus ID 4015
Cytogenetics 5q23.1
Domains Lysyl_oxidase
Protein Families Druggable Genome, Secreted Protein
Gene Summary 'This gene encodes a member of the lysyl oxidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a regulatory propeptide and the mature enzyme. The copper-dependent amine oxidase activity of this enzyme functions in the crosslinking of collagens and elastin, while the propeptide may play a role in tumor suppression. In addition, defects in this gene have been linked with predisposition to thoracic aortic aneurysms and dissections. [provided by RefSeq, Jul 2016]'
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

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