MAL (NM_002371) Human Untagged Clone

CAT#: SC118699

MAL (untagged)-Human mal, T-cell differentiation protein (MAL), transcript variant a

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MAL
• Synonyms: MVP17; VIP17
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_002371, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCCCCCGCAGCGGCGACGGGGGGCAGCACCCTGCCCAGTGGCTTCTCGGTCTTCACCACCTTGCCCG
  ACTTGCTCTTCATCTTTGAGTTTATCTTCGGGGGCCTGGTGTGGATCCTGGTGGCCTCCTCCCTGGTGCC
  CTGGCCCCTGGTCCAGGGCTGGGTGATGTTCGTGTCTGTGTTCTGCTTCGTGGCCACCACCACCTTGATC
  ATCCTGTACATAATTGGAGCCCACGGTGGAGAGACTTCCTGGGTCACCTTGGACGCAGCCTACCACTGCA
  CCGCTGCCCTCTTTTACCTCAGCGCCTCAGTCCTGGAGGCCCTGGCCACCATCACGATGCAAGACGGCTT
  CACCTACAGGCACTACCATGAAAACATTGCTGCCGTGGTGTTCTCCTACATAGCCACTCTGCTCTACGTG
  GTCCATGCGGTGTTCTCTTTAATCAGATGGAAGTCTTCATAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002371 unedited
  CTNTGAGGGNCGGCACGCGCAATTCGGCACGAGGGCCAGCGAGAGGTCTGCGCGGAGTCT
  GAGCGGCGCTCGTCCCGTCCCAAGGCCGACGCCAGCACGCCGTCATGGCCCCCGCAGCGG
  CGACGGGGGGCAGCACCCTGCCCAGTGGCTTCTCGGTCTTCACCACCTTGCCCGACTTGC
  TCTTCATCTTTGATTTTATCTTCGGGGGCCTGGTGTGGATCCTGGTGGCCTCCTCCCTGG
  TGCCCTGGCCCCTGGTCCAGGGCTGGGTGATGTTCGTGTCTGTGTTCTGCTTCGTGGCCA
  CCACCACCTTGATCATCCTGTACATAATTGGAGCCCACGGTGGAGAGACTTCCTGGGTCA
  CCTTGGACGCAGCCTACCACTGCACCGCTGCCCTCTTTTACCTCAGCGCCTCAGTCCTGG
  AGGCCCTGGCCACCATCACGATGCAAGACGGCTTCACCTACAGGCACTACCATGAAAACA
  TTGCTGCCGTGGTGTTCTCCTACATAGCCACTCTGCTCTACGTGGTCCATGCGGTGTTCT
  CTTTAATCAGATGGAAGTCTTCATAAAGCCGCAGTAGAACTTGAGCTGAAAACCCAGATG
  GTGTTAACTGGCCGCCCCACTTTCCGGCATAACTTTTTAGAAAACAGAAATGCCCTTGAT
  GGTGGAAAAAAGAAAACAACCACCCCCCCACTGCCCAAAAAAAAAGCCCTGCCCTGTTGC
  TCGTGGGTGCTGTGTTTACTCTCCCGTGTGCCTTCGCGTCCGGGTTGGGAGCTTGCTGTG
  TCTAACCTCCAACTGCTGTGCTGTCTGCTAGGGTCACCTCCTGTTTGTGAAGGGNGACCT
  NNCTGTCGGGGGTGGGAAGTGGCGACCGTGACCTGAGAAGGAAGAAAGAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002371 unedited
  ACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTGAACATTAAAACATTT
  TATAAAGTATTTCACAGGGTTATCGTCTTCCACCATGGACCTCTGGAAAGATCTGTTGGG
  TGAGTTTTAGTCCCCATGACATGCAGAACATCCATGAAGACTTAAAACATGGCACAAGAT
  GGGGCGCTCGGGAGAGCTTGTGGACAATACCAACAGGTAGTTCTCGAGAGCTGCTCCAGG
  GGTCAGCAGAGGATCTTTCTTTCCTTCTCAGGTCACGGTCGCCACTTCCCACCCCCGAAC
  AAGAAGGTCCCCTTTCACAAACAGGAGGTGACCCTAGCAGACAGCACAGCAGTTGGAGGT
  TAGACACAGCAAGCTCCCAACCCGGACGCGAAGGCACACGGGAGAGTAAACACAGCACCC
  ACGAGCAACAGGGCAGGGCTTTTTTTTTTGGGCAGTGGGGGTGGGGGTTGTTTTCTTTTT
  TCCACCATCAAGGGCATTTCTGTTTTCTAAAAAGTTATGCCGGAAAGTGGGGCGGCCAGT
  TAACACCATCTGGGTTTTCAGCTCAAGTTCTACTGCGGCTTTATGAAGACTTCCATCTGA
  TTAAAGAGAACACCGCATGGACCACGTAGAGCAGAGTGGCTATGTAGGAGAACACCACGG
  CAGCAATGTTTTCATGGTAGTGCCTGTANGTGAAGCCGTCTTGCATCGTGATGGTGGCCA
  GGGCCTNCAGGACTGAGGCGCTGAGGTAAAAGAAGGGCACGGTGCANTGGTAGGCTGCGT
  CCAAGGTGACCCAGGAAGTCTCTCCACCGTGGCTCCATTATGTCAGGATGATCAAGGGGG
  GGGTGGCCCNAANCAAACACAGACACGACATTACCAACCCTGAACCGGGGCCAGGCCCAG
  GGAGGAGGCCCCAGATCCCACCAGCCCCGAAAATACTCAAATGAGAAAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_002371
• Insert Size: 1000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002371.2, NP_002362.1
• RefSeq Size: 1056 bp
• RefSeq ORF: 462 bp
• Locus ID: 4118
• Cytogenetics: 2q11.1
• Protein Families: Transmembrane
• Gene Summary: 'The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3. [provided by RefSeq, May 2012]'
  Transcript Variant: This variant (a) includes both alternatively spliced exons 2 and 3, resulting in the longest isoform (a).