Integrin beta 5 (ITGB5) (NM_002213) Human Untagged Clone

CAT#: SC118751

ITGB5 (untagged)-Human integrin, beta 5 (ITGB5)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ITGB5
• Synonyms: FLJ26658
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_002213 edited
  GAATTCGGCACGAGGCGGCCGCCGGCCCCCGCGGAGTGCAGCGACCGCGCCGCCGCTGAG
  GGAGGCGCCCCACCATGCCGCGGGCCCCGGCGCCGCTGTACGCCTGCCTCCTGGGGCTCT
  GCGCGCTCCTGCCCCGGCTCGCAGGTCTCAACATATGCACTAGTGGAAGTGCCACCTCAT
  GTGAAGAATGTCTGCTAATCCACCCAAAATGTGCCTGGTGCTCCAAAGAGGACTTCGGAA
  GCCCACGGTCCATCACCTCTCGGTGTGATCTGAGGGCAAACCTTGTCAAAAATGGCTGTG
  GAGGTGAGATAGAGAGCCCAGCCAGCAGCTTCCATGTCCTGAGGAGCCTGCCCCTCAGCA
  GCAAGGGTTCGGGCTCTGCAGGCTGGGACGTCATTCAGATGACACCACAGGAGATTGCCG
  TGAACCTCCGGCCCGGTGACAAGACCACCTTCCAGCTACAGGTTCGCCAGGTGGAGGACT
  ATCCTGTGGACCTGTACTACCTGATGGACCTCTCCCTGTCCATGAAGGATGACTTGGACA
  ATATCCGGAGCCTGGGCACCAAACTCGCGGAGGAGATGAGGAAGCTCACCAGCAACTTCC
  GGTTGGGATTTGGGTCTTTTGTTGATAAGGACATCTCTCCTTTCTCCTACACGGCACCGA
  GGTACCAGACCAATCCGTGCATTGGTTACAAGTTGTTTCCAAATTGCGTCCCCTCCTTTG
  GGTTCCGCCATCTGCTGCCTCTCACAGACAGAGTGGACAGCTTCAATGAGGAAGTTCGGA
  AACAGAGGGTGTCCCGGAACCGAGATGCCCCTGAGGGGGGCTTTGATGCAGTACTCCAGG
  CAGCCGTCTGCAAGGAGAAGATTGGCTGGCGAAAGGATGCACTGCATTTGCTGGTGTTCA
  CAACAGATGATGTGCCCCACATCGCATTGGATGGAAAATTGGGAGGCCTGGTGCAGCCAC
  ACGATGGCCAGTGCCACCTGAACGAGGCCAACGAGTACACTGCATCCAACCAGATGGACT
  ATCCATCCCTTGCCTTGCTTGGAGAGAAATTGGCAGAGAACAACATCAACCTCATCTTTG
  CAGTGACAAAAAACCATTATATGCTGTACAAGAATTTTACAGCCCTGATACCTGGAACAA
  CGGTGGAGATTTTAGATGGAGACTCCAAAAATATTATTCAACTGATTATTAATGCATACA
  ATAGTATCCGGTCTAAAGTGGAGTTGTCAGTCTGGGATCAGCCTGAGGATCTTAATCTCT
  TCTTTACTGCTACCTGCCAAGATGGGGTATCCTATCCTGGTCAGAGGAAGTGTGAGGGTC
  TGAAGATTGGGGACACGGCATCTTTTGAAGTATCATTGGAGGCCCGAAGCTGTCCCAGCA
  GACACACGGAGCATGTGTTTGCCCTGCGGCCGGTGGGATTCCGGGACAGCCTGGAGGTGG
  GGGTCACCTACAACTGCACGTGCGGCTGCAGCGTGGGGCTGGAACCCAACAGCGCCAGGT
  GCAACGGGAGCGGGACCTATGTCTGCGGCCTGTGTGAGTGCAGCCCCGGCTACCTGGGCA
  CCAGGTGCGAGTGCCAGGATGGGGAGAACCAGAGCGTGTACCAGAACCTGTGCCGGGAGG
  CAGAGGGCAAGCCACTGTGCAGCGGGCGTGGGGACTGCAGCTGCAACCAGTGCTCCTGCT
  TCGAGAGCGAGTTTGGCAAGATCTATGGGCCTTTCTGTGAGTGCGACAACTTCTCCTGTG
  CCAGGAACAAGGGAGTCCTCTGCTCAGGCCATGGCGAGTGTCACTGCGGGGAATGCAAGT
  GCCATGCAGGTTACATCGGGGACAACTGTAACTGCTCGACAGACATCAGCACATGCCGGG
  GCAGAGATGGCCAGATCTGCAGCGAGCGTGGGCACTGTCTCTGTGGGCAGTGCCAATGCA
  CGGAGCCGGGGGCCTTTGGGGAGATGTGTGAGAAGTGCCCCACCTGCCCGGATGCATGCA
  GCACCAAGAGAGATTGCGTCGAGTGCCTGCTGCTCCACTCTGGGAAACCTGACAACCAGA
  CCTGCCACAGCCTATGCAGGGATGAGGTGATCACATGGGTGGACACCATCGTGAAAGATG
  ACCAGGAGGCTGTGCTATGTTTCTACAAAACCGCCAAGGACTGCGTCATGATGTTCACCT
  ATGTGGAGCTCCCCAGTGGGAAGTCCAACCTGACCGTCCTCAGGGAGCCAGAGTGTGGAA
  ACACCCCCAACGCCATGACCATCCTCCTGGCTGTGGTCGGTAGCATCCTCCTTGTTGGGC
  TTGCACTCCTGGCTATCTGGAAGCTGCTTGTCACCATCCACGACCGGAGGGAGTTTGCAA
  AGTTTCAGAGCGAGCGATCCAGGGCCCGCTATGAAATGGCTTCAAATCCATTATACAGAA
  AGCCTATCTCCACGCACACTGTGGACTTCACCTTCAACAAATCCTACAATGGCACTGTGG
  ACTGATGTTTCCTTCTCCGAGGGGCTGGAGCGGGGATCTGATGAAAAGGTCAGACTGAAA
  CGCCTTGCACGGCTGCTCGGCTTGATCACAGCTCCCTAGGTAGGCACCAYAGRSAMSACM
  KWSWAGWSMKYCTRGKSMRSSWGSSCMMRGWGCCYRYASWGSMWGKWSMSKRRSSWKSYY
  RSCYRTGTCACCTGGCTGCTAGGCCAGAGCCATGCCAGGCTGCGTCCCTCCGAGCTTGGG
  ATAAAGCAAGGGGACCTTGGCGCTCTCAGCTTTCCCTGCCACATCCAGCTTGTTGTCCCA
  ATGAAATACTGAGATGCTGGGCTGTCTCTCCCTTCCAGGAATGCTGGGCCCCCAGCCTGG
  CCAGACAAGAAGACTGTCAGGAAGGGTCGGAGTCTGTAAAACCAGCATACAGTTTGGCTT
  TTTTCACATTGATCATTTTTATATGAAATAAAAAGATCCTGCATTTATGGTGTAGTTCTG
  AGTCCTGAGACTTTTCTGCGTGATGGCTATGCCTTGCACACAGGTGTTGGTGATGGGGCT
  GTTGAGATGCCTGTTGAAGGTACATCGTTTGCAAATGTCAGTTTCCTCTCCTGTCCGTGT
  TTGTTTAGTACTTTTATAATGAAAAGAAACAAGATTGTTTGGGATTGGAAGTAAAGATTA
  AAACCAAAAAAAAAAAAAAAAAACTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002213 unedited
  GTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCGGCCGCCGGCCCCCGC
  GGAGTGCAGCGACCGCGCCGCCGCTGAGGGAGGCGCCCCACCATGCCGCGGGCCCCGGCG
  CCGCTGTACGCCTGCCTCCTGGGGCTCTGCGCGCTCCTGCCCCGGCTCGCAGGTCTCAAC
  ATATGCACTAGTGGAAGTGCCACCTCATGTGAAGAATGTCTGCTAATCCACCCAAAATGT
  GCCTGGTGCTCCAAAGAGGACTTCGGAAGCCCACGGTCCATCACCTCTCGGTGTGATCTG
  AGGGCAAACCTTGTCAAAAATGGCTGTGGAGGTGAGATAGAGAGCCCAGCCAGCAGCTTC
  CATGTCCTGAGGAGCCTGCCCCTCAGCAGCAAGGGTTCGGGCTCTGCAGGCTGGGACGTC
  ATTCAGATGACACCACAGGAGATTGCCGTGAACCTCCGGCCCGGTGACAAGACCACCTTC
  CAGCTACAGGTTCGCCAGGTGGAGGACTATCCTGTGGACCTGTACTACCTGATGGACCTC
  TCCCTGTCCATGAAGGATGACTTGGACAATATCCGGAGCCTGGGCACCAAACTCGCGGAG
  GAGATGAGGAAGCTCACCAGCAACTTCCGGTTGGGATTTGGGTCTTTTGTTGATAAGGAC
  ATCTCTCCTTTCTCCTACACGGCANCCGAGTACCAGACCAATCCGTGCATTGGGTTACAG
  NTGTTTCCAAATTGCGTCCCTCCTTTGGGNTNCGNCATCTGCTGCCTCTCCAGACAGAGT
  GGACAGCTTCATGGAGGAAAAGTCGAACAGAGGGTGTCCCGAACCGAGATGCCCTGNAGG
  GGGGCTTNGATGCAGTACTCCAGNCAGCCGTCTGCAAGGAAAAAAATGGCTGGNCGAAGG
  ATGCACTGCATTGGCTGGNTGTCACAACAGAATGAGTGCC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002213 unedited
  NNTTTACTTGNACCGCGGNCCCGCATTCTANGATCGAGTTTTTTTTTTTTTTTTTTGGTT
  TTAATCTTTACTTCCAATCCCAAACAATCTTGTTTCTTTTCATTATAAAAGTACTAAACA
  AACACGGACAGGAGAGGAAACTGACATTTGCAAACGATGTACCTTCAACAGGCATCTCAA
  CAGCCCCATCACCAACACCTGTGTGCAAGGCATAGCCATCACGCAGAAAAGTCTCAGGAC
  TCAGAACTACACCATAAATGCAGGATCTTTTTATTTCATATAAAAATGATCAATGTGAAA
  AAAGCCAAACTGTATGCTGGTTTTACAGACTCCGACCCTTCCTGACAGTCTTCTTGTCTG
  GCCAGGCTGGGGGCCCAGCATTCCTGGAAGGGAGAGACAGCCCAGCATCTCAGTATTTCA
  TTGGGACAACAAGCTGGATGTGGCAGGGAAAGCTGAGAGCGCCAAGGTCCCCTTGCTTTA
  TCCCAAGCTCGGAGGGACGCAGCCTGGCATGGCTCTGGCCTAGCAGCCAGGTGACATGGC
  CAGGCACCTTCCTGTACAGGCACTGTGGGCTCCTGGCCCAGGCTCACTAGAAGGTCTTCT
  CTGTGGTGCCTACCTAGGGAGCTGTGATCAAGCCGAGCAGCCGTGCAAGGCGTTTCAGTC
  TGACCTTTTCATCAGATCCCCGCTCCAGCCCCTCGGAGAAGGAAACATCAGTCCACAGTG
  CCATTGTANGATTTGTTGAAGGTGAAGTCCACAGTGTGCGTGGAGATAGGCTTTCTGTAT
  ATGGATTTGAAGCCATTCATAGCGGGCCCTGGATCGCTCGCTCTGAAACTTTGCANACTC
  CCTTCGGTCGTGGATGGTGACAAGCAGCTTTCAGATAGCCAGNAGTGGCAGCCCAACAAG
  GNAGATGCTACCGACCACANCCAGGAGATAGTCATGGCGTTGGGGGGTGGTTTCACACTC
  T
  
• Restriction Sites: NotI-NotI
• ACCN: NM_002213
• Insert Size: 3410 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002213.3, NP_002204.2
• RefSeq Size: 3392 bp
• RefSeq ORF: 2400 bp
• Locus ID: 3693
• Cytogenetics: 3q21.2
• Domains: VWA, INB, PSI, EGF
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Regulation of actin cytoskeleton
• Gene Summary: 'This gene encodes a beta subunit of integrin, which can combine with different alpha chains to form a variety of integrin heterodimers. Integrins are integral cell-surface receptors that participate in cell adhesion as well as cell-surface mediated signaling. The alphav beta5 integrin is involved in adhesion to vitronectin. [provided by RefSeq, Aug 2017]'
  Transcript Variant: This variant (1) encodes the longest isoform (1).