Cathepsin D (CTSD) (NM_001909) Human Untagged Clone

CAT#: SC118936

CTSD (untagged)-Human cathepsin D (CTSD)


  "NM_001909" in other vectors (6)

Reconstitution Protocol

USD 310.00

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol CTSD
Synonyms CLN10; CPSD; HEL-S-130P
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_001909 edited
GAATTCGGCACGAGGCCGGCTATAAGCGCACGGCCTCGGCGACCCTCTCCGACCCGGCCG
CCGCCGCCATGCAGCCCTCCAGCCTTCTGCCGCTCGCCCTCTGCCTGCTGGCTGCACCCG
CCTCCGCGCTCGTCAGGATCCCGCTGCACAAGTTCACGTCCATCCGCCGGACCATGTCGG
AGGTTGGGGGCTCTGTGGAGGACCTGATTGCCAAAGGCCCCGTCTCAAAGTACTCCCAGG
CGGTGCCAGCCGTGACCGAGGGGCCCATTCCCGAGGTGCTCAAGAACTACATGGACGCCC
AGTACTACGGGGAGATTGGCATCGGGACGCCCCCCCAGTGCTTCACAGTCGTCTTCGACA
CGGGCTCCTCCAACCTGTGGGTCCCCTCCATCCACTGCAAACTGCTGGACATCGCTTGCT
GGATCCACCACAAGTACAACAGCGACAAGTCCAGCACCTACGTGAAGAATGGTACCTCGT
TTGACATCCACTATGGCTCGGGCAGCCTCTCCGGGTACCTGAGCCAGGACACTGTGTCGG
TGCCCTGCCAGTCAGCGTCGTCAGCCTCTGCCCTGGGCGGTGTCAAAGTGGAGAGGCAGG
TCTTTGGGGAGGCCACCAAGCAGCCAGGCATCACCTTCATCGCAGCCAAGTTCGATGGCA
TCCTGGGCATGGCCTACCCCCGCATCTCCGTCAACAACGTGCTGCCCGTCTTCGACAACC
TGATGCAGCAGAAGCTGGTGGACCAGAACATCTTCTCCTTCTACCTGAGCAGGGACCCAG
ATGCGCAGCCTGGGGGTGAGCTGATGCTGGGTGGCACAGACTCCAAGTATTACAAGGGTT
CTCTGTCCTACCTGAATGTCACCCGCAAGGCCTACTGGCAGGTCCACCTGGACCAGGTGG
AGGTGGCCAGCGGGCTGACCCTGTGCAAGGAGGGCTGTGAGGCCATTGTGGACACAGGCA
CTTCCCTCATGGTGGGCCCGGTGGATGAGGTGCGCGAGCTGCAGAAGGCCATCGGGGCCG
TGCCGCTGATTCAGGGCGAGTACATGATCCCCTGTGAGAAGGTGTCCACCCTGCCCGCGA
TCACACTGAAGCTGGGAGGCAAAGGCTACAAGCTGTCCCCAGAGGACTACACGCTCAAGG
TGTCGCAGGCCGGGAAGACCCTCTGCCTGAGCGGCTTCATGGGCATGGACATCCCGCCAC
CCAGCGGGCCACTCTGGATCCTGGGCGACGTCTTCATCGGCCGCTACTACACTGTGTTTG
ACCGTGACAACAACAGGGTGGGCTTCGCCGAGGCTGCCCGCCTCTAGTTCCCAAGGCGTC
CGCGCGCCAGCACAGAAACAGAGGAGAGTCCCAGAGCAGGAGGCCCCTGGCCCAGCGGCC
CCTCCCACACACACCCACACACTCGCCCGCCCACTGTCCTGGGCGCCCTGGAAGCCGGCG
GCCCAAGCCCGACTTGCTGTTTTGTTCTGTGGTTTTCCCCTCCCTGGGTTCAGAAATGCT
GCCTGCCTGTCTGTCTCTCCATCTGTTTGGTGGGGGTAGAGCTGATCCAGAGCACAGATC
TGTTTCGTGCATTGGAAGACCCCACCCAAGCTTGGCAGCCGAGCTCGTGTATCCTGGGGC
TCCCTTCATCTCCAGGGAGTCCCCTCCCCGGCCCTACCAGCGCCCGCTGGGCTGAGCCCC
TACCCCACACCAGGCCGTCCTCCCGGGCCCTCCCTTGGAAACCTGCCCTGCCTGAGGGCC
CCTCTGCCCAGCTTGGGCCCAGCTGGGCTCTGCCACCCTACCTGTTCAGTGTCCCGGGCC
CGTTGAGGATGAGGCCGCTAGAGGCCTGAGGATGAGCTGGAAGGAGTGAGAGGGGACAAA
ACCCACCTTGTTGGAGCCTGCAGGGTGGTGCTGGGACTGAGCCAGTCCCAGGGGCATGTA
TTGGCCTGGAGGTGGGGTTGGGATTGGGGGCTGGTGCCAGCCTTCCTCTGCAGCTGACCT
CTGTTGTCCTCCCCTTGGGCGGCTGAGAGCCCCAGCTGACATGGAAATACAGTTGTTGGC
CTCCGGCCTCCCCTCAAAAAAAAAAAAAAAAAACTCGAC
>OriGene 5' read for NM_001909 unedited
NGGTTCAAATTTGTATACGACTCCTATAGGCGGCCCGCGAATTCGCACGAGGCCGGCTAT
AAGCGCACGGCCTCGGCGACCCTCTCCGACCCGGCCGCCGCCGCCATGCAGCCCTCCAGC
CTTCTGCCGCTCGCCCTCTGCCTGCTGGCTGCACCCGCCTCCGCGCTCGTCAGGATCCCG
CTGCACAAGTTCACGTCCATCCGCCGGACCATGTCGGAGGTTGGGGGCTCTGTGGAGGAC
CTGATTGCCAAAGGCCCCGTCTCAAAGTACTCCCAGGCGGTGCCAGCCGTGACCGAGGGG
CCCATTCCCGAGGTGCTCAAGAACTACATGGACGCCCAGTACTACGGGGAGATTGGCATC
GGGACGCCCCCCCAGTGCTTCACAGTCGTCTTCGACACGGGCTCCTCCAACCTGTGGGTC
CCCTCCATCCACTGCAAACTGCTGGACATCGCTTGCTGGATCCACCACAAGTACAACAGC
GACAAGTCCAGCACCTACGTGAAGAATGGTACCTCGTTTGACATCCACTATGGCTCGGGC
AGCCTCTCCGGGTACCTGAGCCAGGACACTGTGTCGGTGCCCTGCCAGTCAGCGTCGTCA
GCCTCTGCCCTGNGCGGTGTCAAAGTGGAGAGGCAGGTCTTTGGGGAGGCCACCAAGCAG
CCAGGCATCACCTTCATCGCAGCCAAGTTCGATGGCATCCTGGGCATGGCCTACCCCCGC
ATCTCCGTCAACAACGTGCTGCCCGTCTTCGACAACCTGATGCAGCAGAAGCTGGTGGAC
CAGAACATCTTCTCCTTCTACCTGAGCAGGNACCCAGATGCGCAGCCTGGNGGGTGAGCT
GATGCCTGGTGGCACAGACTCCAAGATTACAGGGTTTCTCTGTCTACCTGAATGTCACCC
CGCAGGCTACTGGC
>OriGene 3' read for NM_001909 unedited
ACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGAGGGGAGGCCGNGAGC
CAACAACTGTATTTCCATGTCAGCTGGGGCTCTCAGCCGCCCAAGGGGAGGACAACAGAG
GTCAGCTGCAGAGGAAGGCTGGCACCAGCCCCCAATCCCAACCCCACCTCCAGGCCAATA
CATGCCCCTGGGACTGGCTCAGTCCCAGCACCACCCTGCAGGCTCCAACAAGGTGGGTTT
TGTCCCCTCTCACTCCTTCCAGCTCATCCTCAGGCCTCTAGCGGCCTCATCCTCAACGGG
CCCGGGACACTGAACAGGTAGGGTGGCAGAGCCCAGCTGGGCCCAAGCTGGGCAGAGGGG
CCCTCAGGCAGGGCAGGTTTCCAAGGGAGGGCCCGGGAGGACGGCCTGGTGTGGGGTAGG
GGCTCAGCCCAGCGGGCGCTGGTAGGGCCGGGGAGGGGACTCCCTGGAGATGAAGGGAGC
CCCAGGATACACGAGCTCGGCTGCCAAGCTTGGGTGGGGTCTTCCAATGCACGAAACAGA
TCTGTGCTCTGGATCAGCTCTACCCCCACCAAACAGATGGAGAGACAGACAGGCAGGCAG
CATTTCTGAACCCAGGGAGGGGAAAACCACAGAACANAACAGCAAGTCGGGCTTGGGCCG
CCGGCTTCCAGGGCGCCCANNACAGTGGGCGGGCAANTGTGTGGGTGTGTGTGGGAGGGG
CCCCCTGGCCAGGGGCCTCCTGCTCTGGGACTCTNCTCTGTTTCTGTGCTGGCGCGCGGA
CGCCTTGGGACTAGAGGGCGGCANCTCCGCGAAGCCCACCTGTTGGTGTACGGGTCAACA
CGTGTATTAGCGGCGATGAAAACCTCCCCCAGATCCAAATGGCCCCCGGGTTGCGGGATG
TCATGCCATGAACCGCTCAGCAAAGGTCTTCCCN
Restriction Sites NotI-NotI     
ACCN NM_001909
Insert Size 2190 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_001909.3, NP_001900.1
RefSeq Size 2205 bp
RefSeq ORF 1239 bp
Locus ID 1509
Cytogenetics 11p15.5
Domains asp
Protein Families Druggable Genome, Protease
Protein Pathways Lysosome
Gene Summary 'This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015]'

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