DLX4 (NM_001934) Human Untagged Clone

CAT#: SC118955

DLX4 (untagged)-Human distal-less homeobox 4 (DLX4), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DLX4
• Synonyms: BP1; DLX7; DLX8; DLX9; OFC15
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC118955 sequence for NM_001934 edited (data generated by NextGen Sequencing)
  ATGAAACTGTCCGTCCTACCCCCTCGCTCCCTCCTCGCCCCCTACACCGTGTTGTGCTGC
  CCACCAGACTCGGAGAAGCCGCGGCTGTCCCCGGAACCCTCCGAGCGGCGCCCTCAGGCC
  CCCGCCAAAAAGCTCCGCAAGCCGAGGACCATCTACTCCAGCCTGCAGCTGCAGCACCTA
  AACCAGCGTTTCCAGCACACGCAGTACCTGGCGCTGCCCGAGAGGGCCCAGCTGGCAGCG
  CAGCTCGGCCTCACCCAGACCCAGGTAAAGATCTGGTTTCAGAACAAACGCTCCAAGTAT
  AAGAAGCTCCTGAAGCAGAATTCTGGGGGGCAGGAAGGGGACTTCCCTGGGAGGACCTTC
  TCTGTGTCTCCCTGCTCCCCACCCCTCCCCTCCCTCTGGGATCTACCCAAGGCAGGGACC
  CTGCCCACCAGTGGCTATGGCAACAGCTTTGGAGCCTGGTATCAGCATCACTCCTCAGAT
  GTCCTGGCTTCGCCTCAGATGATGTGA
  
  Clone variation with respect to NM_001934.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001934 unedited
  TTTAGTTCANAATTGTATACGACTCACTATAGGCGGCCGCGNAATTCGCACCAGGCTCTG
  TGCGCGCTGCCCAACGAAGGAGGGGCTGCCCCACGCAGACCCGGCTTCTGGGGGTCCCTG
  GAAACCCAGGCGGCCACGGTGTGGCGGGGGAGACATGGTCACTTTTCCTGCAGGGTGCGC
  CTGAGCAGAGGGGCAGCCCGTTACAGTAGGCGAGGCCAGGGCAAACCCGGGGTCACTATC
  AGCGCTGCGAGACTGGTATTCAAGGTCCTCTCAGCCGGGCCTCTCACCCACCCCGCTGGC
  CGCAGCCGGAGGCTGCCACGCGGACACCGTCTCAAGCCTCTGAGCATTGCTCTGAGCCTC
  TGCCTGCAATGTCCTTCCTCTGTCATCTCTAGGCCTCGGCTCAGCCCTGGACCTAGCCTT
  TCTGCCCCGCCCTACCCCAAGCTGGCGCCACCGCCCGTGGCTGAACTCCGACCTCCNACC
  GCAGGCGCCGCGGTACCCTGGCTGTGGCCCTCGGCGCTTTCTTCCTAGGGTCACAGGACC
  CATACGAGTGGGAGCTCCCTGGGAGCAGAACTGCGTCTTGTATCACCTGGCGCGGTGAAC
  GTGNGGGGTTGAAACGCTCCACGCGGAAGGTAGAGGGCAGGGGCCAAGGGGGCGATCCTG
  GTGGCTGCGCTTTTTGCTATTTGCTGCCGACGGCATGCAGACGAGATGCAAATAAGCTTA
  TGAAACTGTCCGTCCTACCCCCTCGCTCCCTCCTCGCCCCCTACACCGTGTTGTGCTGCC
  CACCAGACTCGGAGAAACCGCGGCTGTCCCCGGAACCCTTCGAGCGGCGCCCTCAGGCCC
  CCGCCCAAAGCTCCGCAGGCCGAGGACATCTACTCCAGCCTGCAGCTGCAGCACCTAAAA
  CAGCGT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001934 unedited
  NNGGGCACTCTAGGTACGCGGCCGCCTGCTANGATCGGTTTTTTTTTTTTTTTTTTAGGA
  GAAACTAATTACCCTAGTCCCAATTCCACATTTCTCTGCATCTCTTCTACCTCCCAGTAT
  GGTAAGTAGGTAAATCAGTTATGGGGGTAACGGGCTGACCTCCAAGGAAAAATCGCTGGG
  TGGGTGGGAGCTGATGGTGGTCCACTTCTGCTTTTGCTCACAAATGGGTTGTGCAAGGCC
  AAAGGCATACAAAGAAAAAAAAATACTCAATGTTTCTTGCTGATTTTGCACCCAGGCTGT
  AGTGGCGATTCAGTCCTTTTCAAGAAAGCAGGGAGAGGAGAAAGGGAGAGAGGGAAGAAG
  GAGTGGGGGAGTGGCAAGACCAAGGGTTCTGGGGACAGTCTCAACTCCAGCCAATGGCTC
  TCTCTCCAGAGTCTTTGTCCAGCTGGAGTGAAGGTGTCCAGTCCATGGTAGTGGTGGGGA
  CAATGATTATATAAGGCTGAGGTCCTTGATTTAGCTGTTAGGGTTAGGGGTACAGGCTCT
  GCTCCATTCCTTTTTCTCCTCTAACTGCTTGTCCTCCAGAGAAAACCCATCTGGAGCTGG
  TTTCCTCCCAGCCCATAAGGGGTGCAGGTGGACTGCCTGGGTCCTGGGCTTTGCAGGAAG
  GCTGTGGGCCTGACCCGCCCTTCCCCAGATTCACATCATCTGAGGCGAAGCCAGGACATC
  TGANGAGTGATGCTGATACCAGGCTCCAAAGCTGTTGCCATAGCCACTGGTGGGCAGGGT
  CCCTGCCTGGTTTTCCCCCCAAAAGGGAGGGGAAGGTTTTGNNAAACAANNAAAATTCAT
  AACTAGTCCA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_001934
• Insert Size: 2350 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001934.2, NP_001925.2
• RefSeq Size: 1405 bp
• RefSeq ORF: 507 bp
• Locus ID: 1748
• Cytogenetics: 17q21.33
• Domains: homeobox
• Protein Families: Transcription Factors
• Gene Summary: 'Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. Three transcript variants have been described for this gene, however, the full length nature of one variant has not been described. Studies of the two splice variants revealed that one encoded isoform functions as a repressor of the beta-globin gene while the other isoform lacks that function. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (2) differs at the 5' end, and utilizes an alternate start codon compared to variant 1. This results in a shorter isoform (b) with a distinct N-terminus compared to isoform a, and lacks the beta-globin repressor function.