COX7A2 (NM_001865) Human Untagged Clone

CAT#: SC118990

COX7A2 (untagged)-Human cytochrome c oxidase subunit VIIa polypeptide 2 (liver) (COX7A2), nuclear gene encoding mitochondrial protein, transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: COX7A2
• Synonyms: COX7AL; COX7AL1; COXVIIa-L; COXVIIAL; VIIAL
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001865, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCATACGCAAGACTCGGAGGTAGTTCCGGTTCCGGCGTGGCCATTTTCGTTGGTGGTGTTCAGTTGTG
  GCGGTTGCTGGTCAGTAACAGCCAAGATGCTGCGGAATCTGCTGGCTCTTCGTCAGATTGGGCAGAGGAC
  GATAAGCACTGCTTCCCGCAGGCATTTTAAAAATAAAGTTCCGGAGAAGCAAAAACTGTTCCAGGAGGAT
  GATGAAATTCCACTGTATCTAAAGGGTGGGGTAGCTGATGCCCTCCTGTATAGAGCCACCATGATTCTTA
  CAGTTGGTGGAACAGCATATGCCATATATGAGCTGGCTGTGGCTTCATTTCCCAAGAAGCAGGAGTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001865 unedited
  TCACTATTTTGTAATACGACTCACTATAGGGCGGCCGCGNATTCGGCACGAGGGTTCAGT
  TGTGGCGGTTGCTGGTCAGTAACAGCCAAGATGCTGCGGAATCTGCTGGCTCTTCGTCAG
  ATTGGGCAGAGGACGATAAGCACTGCTTCCCGCAGGCATTTTAAAAATAAAGTTCCGGAG
  AAGCAAAAACTGTTCCAGGAGGATGATGAAATTCCACTGTATCTAAAGGGTGGGGTAGCT
  GATGCCCTCCTGTATAGAGCCACCATGATTCTTACAGTTGGTGGAACAGCATATGCCATA
  TATGAGCTGGCTGTGGCTTCATTTCCTAAGAAGCAGGAGTGACTTCAGTCATCCCAGCAA
  TCGCTTGGTTCAGTTTCATTCAGCTCTCTATGGACCAGTAATCTGATAAATAACCGAGCT
  CTTCTTTGGGGATCAATATTTATTGACTTGTAGTAACTGCCACCAATAAAGCAGTCTTTA
  CCATGAAAAAAAAAAAAAAAAAACTCCACTCTAGATTGCGGCCGCGGTCATAGCTGTTTC
  CTGAACAGATCCCGGGTGGCATCCCTGTGACCCCTCCCCAGTGCCTCTCCTGGCCCTGGA
  AGTTGCCACTCCAGTGCCCACCAGCCTTGTCCTAATAAAATTAAGTTGCATCATTTTGTC
  TGACTAGGTGTCCTTCTATATATTATGGGGTGGAGGGGGGTGGTATGGAGCAAGGGGCAA
  GTTGGGAAGACAACCTGTANGGCCTGCGGNGTCTATTGNGAACCAAGCTGGAGTGCAGTG
  GCACAATCTTGGGCTCACTGCATCTCCGNCTCCTGGGTTCAAGCGATTCTCCTGCCTCAG
  CCTCCCGAGNNTGTTGGATTNCCAGCATGCATGACCCAGCTCAGCTAATTNTNGNTTTTT
  TGGTAGAGACGGGGTTTCACCATATGGGCCAGCTGGTCTCCACTNCTATCTCAGN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001865 unedited
  GGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTCTGGTAAAGACTGCTTTATTGG
  TGGCAGTTACTACAAGTCAATAAATATTGATCCCCAAACAAGAGCTCGGTTATTTATCAG
  ATTACTGGTCCATAGAGAGCTGAATGAAACTGAACCAAGCGATTGCTGGGATGACTGAAG
  TCACTCCTGCTTCTTAGGAAATGAAGCCACAGCCAGCTCATATATGGCATATGCTGTTCC
  ACCAACTGTAAGAATCATGGTGGCTCTATACAGGAGGGCATCAGCTACCCCACCCTTTAG
  ATACAGTGGAATTTCATCATCCTCCTGGAACAGTTTTTGCTTCTCCGGAACTTTATTTTT
  AAAATGCCTGCGGGAAGCAGTGCTTATCGTCCTCTGCCCAATCTGACGAAGAGCCAGCAG
  ATTCCGCAGCATCTTGGCTGTTACTGACCAGCAACCGCCACAACTGAACCCTCGTGCCGA
  ATTCGCGGCCGCCCTATAGTGAGTCGTATTACAAAATTCTGACGGCTCACTAAACGAGCT
  CTGCTTATATAGACCTCCCACCGTACACGCCTACCGCCCATTTGCCGCCCCGGGGCGGGG
  CTATTACGACATTTTGGGAAAGCCCGCTGATTTTGGGGCCCAAACAAACCCCCATTGACC
  GTAATGGGGTGGAGACTTTGAAAATTCCGGGGAGGAAAACCGCTATCCCCGCCCATGGGG
  GTCCCGCCCACCCCGCTTCCACCTGGTTACTAGCGGCGGACTATACCCCTAACGCCCCTG
  CCAAGATGGAAAAGCTCCGCAAGGGCACTGCCCGGGCATAATGGCCCCGGCGGCCACTTA
  CCGGTTTTGGACGGCAATAAGGGGGCCGGACCTGGGAATTTCACACACCCGTGAGGTCTC
  GCGAANGGGGCCGCTTAACCGCAAATCTTCCCCCTTTGCCGCCCCCGAGAAGTCTCTTCG
  TCGCCTCTATCGCGCCCCAACCCTCTTNTCTTCCGCCCTATGGTGCGGGCCCGCGTGGCG
  CGCGGATCACCCCCGCCGTCTCTTACCCGCGCGCNTCTCGCCCGCCGCGCGCTCTCCTAT
  CGGNGCTTGANANTACGCGACCTN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_001865
• Insert Size: 5310 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001865.2, NP_001856.1
• RefSeq Size: 470 bp
• RefSeq ORF: 252 bp
• Locus ID: 1347
• Cytogenetics: 6q14.1
• Domains: COX7a
• Protein Families: Transmembrane
• Protein Pathways: Alzheimer's disease, Cardiac muscle contraction, Huntington's disease, Oxidative phosphorylation, Parkinson's disease
• Gene Summary: 'Cytochrome c oxidase, the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes, and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, while the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (liver isoform) of subunit VIIa, with this polypeptide being present in both muscle and non-muscle tissues. In addition to polypeptide 2, subunit VIIa includes polypeptide 1 (muscle isoform), which is present only in muscle tissues, and a related protein, which is present in all tissues. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4 and 14. [provided by RefSeq, Oct 2009]'
  Transcript Variant: This variant (1) encodes the longer isoform (a). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.