COX7C (NM_001867) Human Untagged Clone

CAT#: SC118992

COX7C (untagged)-Human cytochrome c oxidase subunit VIIc (COX7C), nuclear gene encoding mitochondrial protein

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: COX7C
• Synonyms: cytochrome-c oxidase chain VIIc; cytochrome c oxidase subunit VIIc
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC118992 sequence for NM_001867 edited (data generated by NextGen Sequencing)
  ATGTTGGGCCAGAGCATCCGGAGGTTCACAACCTCTGTGGTCCGTAGGAGCCACTATGAG
  GAGGGCCCTGGGAAGAATTTGCCATTTTCAGTGGAAAACAAGTGGTCGTTACTAGCTAAG
  ATGTGTTTGTACTTTGGATCTGCATTTGCTACACCCTTCCTTGTAGTAAGACACCAACTG
  CTTAAAACATAA
  
  Clone variation with respect to NM_001867.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001867 unedited
  TGTAGATTTTGTAATACGACTCACTATTAGGGCGGCCGCGAATTCGCACGAGGCCGGGGA
  ACAAGGTCGTGAAAAAAAGGTCTTGGTGAGGTGCCGCCATTTCATCTGTCCTCATTCTCT
  GCGCCTTTCGCAGAGCTTCCAGCAGCGGTATGTTGGGCCAGAGCATCCGGAGGTTCACAA
  CCTCTGTGGTCCGTAGGAGCCACTATGAGGAGGGCCCTGGGAAGAATTTGCCATTTTCAG
  TGGAAAACAAGTGGTCGTTACTAGCTAAGATGTGTTTGTACTTTGGATCTGCATTTGCTA
  CACCCTTCCTTGTAGTAAGACACCAACTGCTTAAAACATAAGGATGTTTCAGTTCCTCCA
  TTTAACAGATATGAAGAGCATTTTAAGAGGTGCAGCCTCTGGAAGTGGATCAAACTAGAA
  CTCATATGCCATACTAGATATGTTTGTCAATAAACTTATGACGTGAAAAAAAAAAAAAAA
  AAACTCGACTCTAGATTGCGGCCGCGGTCATAGCTGTTTCCTGAACAGATCCCGGGTGGC
  ATCCCTGTGACCCCTCCCCAGTGCCTCTCCTGGCCCTGGAAGTTGCCACTCCAGTGCCCA
  CCAGCCTTGTCCTAATAAAATTAAGTTGCATCATTTTGTCTGACTAGGTGTCCTTCTATA
  ATATTATGGGGTGGAGGGGGGTGGTATGGAGCAAGGGCAAGTTGGGAAGACACCCTGTAG
  GCCTGCGGGGCCTATTGGGACCAGGCTGGATGCAGTGGCACATCCTGGGTCACTGCATTT
  CCGCTCCTGGGTTAAGCGATCTCCTGCCCAAGCCCCCCAGTTGTGGGTTCCCGGCTGCTT
  GACAGGCTCACTAATTTTGTTTTTTTGGAGAGAACGGGTTTCACATTTTGGCCAGGCTGG
  GCTCCACTTC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001867 unedited
  AAATTCTGCACNCGCGGCCGCAATTTTACGATCGAGTTTTTTTTTTTTTTTTTTCACGTC
  ATAAGTTTATTGACAAACATATCTAGTATGGCATATGAGTTCTAGTTTGATCCACTTCCA
  GAGGCTGCACCTTTTAAAATGCTCTTCATATCTGTTAAATGGAGGAACTGAAACATCCTT
  ATGTTTTAAGCAGTTGGTGTCTTACTACAAGGAAGGGTGTAGCAAATGCAGATCCAAAGT
  ACAAACACATCTTAGCTAGTAACGACCACTTGTTTTCCACTGAAAATGGCAAATTCTTCC
  CAGGGCCCTCCTCATAGTGGCTCCTACGGACCACAGAGGTTGCGAACCTCCGGATGCTCT
  GGCCCAACATACCGCTGCTGGAAGCTCTGCGAAAGGCGCAGAGAATGAGGACAGATGAAA
  TGGCGGCACCTCACCAAGACCTTTTTTTTCACGACCTTGTTCCCCGGCCTCGTGCCGAAT
  TCGCGGCCGCCCTATAGTGAGTCGTATTACAAAATTCTGACGGTTCACTAAACGAGCTCT
  GCTTATATAGACCTCCCACCGTACACGCCTACCGCCCATTTGCGTCAACGGGGCCGGGGT
  TATTTACAACATTTTTGGAAAGCCCCCGCTGATTTTCGGTGCCCAAACCAACACCTCCCA
  TTTGACGTCCAATGGCGGCTGGCAAAACTTTGGAAAATTCCCCCGTCGAGACAAAACCCG
  TTTATCCAACGCCCCACTTGGTGTCCCTGCCAACACCGTCATCACCCATCGTAATAACCG
  ATAGACTAAAAACCTCAAATGCACCCGCCCACACTCGAAACCTCCCCGAAAGGTCATTGA
  CCCGCGCCCTAATGCCACGGCGGGCCCATTAACCCGCCTTTGAACGTCCATAGGGGGCCC
  GCCCTCTGCCCTTACGACCCCCTTGTAGTACATCGCCACCGGGGGAATCTTCCCCGAAAA
  ACCCTCCCCCCTGCACCCCG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_001867
• Insert Size: 480 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001867.2, NP_001858.1
• RefSeq Size: 448 bp
• RefSeq ORF: 192 bp
• Locus ID: 1350
• Cytogenetics: 5q14.3
• Protein Pathways: Alzheimer's disease, Cardiac muscle contraction, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease
• Gene Summary: 'Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes subunit VIIc, which shares 87% and 85% amino acid sequence identity with mouse and bovine COX VIIc, respectively, and is found in all tissues. A pseudogene COX7CP1 has been found on chromosome 13. [provided by RefSeq, Jul 2008]'