CD48 (NM_001778) Human Untagged Clone

CAT#: SC119012

CD48 (untagged)-Human CD48 molecule (CD48)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CD48
• Synonyms: BCM1; BLAST; BLAST1; hCD48; mCD48; MEM-102; SLAMF2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001778 edited
  GAATTCGGCACGAGGCTGTCTCCTGCGTTGCTGGGAAGTTCTGGAAGGAAGCATGTGCTC
  CAGAGGTTGGGATTCGTGTCTGGCTCTGGAATTGCTACTGCTGCCTCTGTCACTCCTGGT
  GACCAGCATTCAAGGTCACTTGGTACATATGACCGTGGTCTCCGGCAGCAACGTGACTCT
  GAACATCTCTGAGAGCCTGCCTGAGAACTACAAACAACTAACCTGGTTTTATACTTTCGA
  CCAGAAGATTGTAGAATGGGATTCCAGAAAATCTAAGTACTTTGAATCCAAATTTAAAGG
  CAGGGTCAGACTTGATCCTCAGAGTGGCGCACTGTACATCTCTAAGGTCCAGAAAGAGGA
  CAACAGCACCTACATCATGAGGGTGTTGAAAAAGACTGGGAATGAGCAAGAATGGAAGAT
  CAAGCTGCAAGTGCTTGACCCTGTACCCAAGCCTGTCATCAAAATTGAGAAGATAGAAGA
  CATGGATGACAACTGTTATCTGAAACTGTCATGTGTGATACCTGGCGAGTCTGTAAACTA
  CACCTGGTATGGGGACAAAAGGCCCTTCCCAAAGGAGCTCCAGAACAGTGTGCTTGAAAC
  CACCCTTATGCCACATAATTACTCCAGGTGTTATACTTGCCAAGTCAGCAATTCTGTGAG
  CAGCAAGAATGGCACGGTCTGCCTCAGTCCACCCTGTACCCTGGCCCGGTCCTTTGGAGT
  AGAATGGATTGCAAGTTGGCTAGTGGTCACGGTGCCCACCATTCTTGGCCTGTTACTTAC
  CTGAGATGAGCTCTTTTAACTCAAGCGAAACTTCAAGGCCAGAAGATCTTGCCTGTTGGT
  GATCATGCTCCTCACCAGGACAGAGACTGTATAGGCTGACCAGAAGCATGCTGCTGAATT
  ATCAACGAGGATTTTCAAGTTAACTTTTAAATACTGGTTATTATTTAATTTTATATCCCT
  TTGTTGTTTTCTAGTACACAGAGATATAGAGATACACATGCTTTTTTCCCACCCAAAATT
  GTGACAACATTATGTGAATGTTTTATTATTTTTTAAAATAAACATTTGATATAATTATCA
  ATTAACTGAAAAAAAAAAAAAAAAAACTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001778 unedited
  NTAAGGTTACGATTTGTATACGACTCATATAGGCGGCCGCGNAATTCGCACGAGGCTGTC
  TCCTGCGTTGCTGGGAAGTTCTGGAAGGAAGCATGTGCTCCAGAGGTTGGGATTCGTGTC
  TGGCTCTGGAATTGCTACTGCTGCCTCTGTCACTCCTGGTGACCAGCATTCAAGGTCACT
  TGGTACATATGACCGTGGTCTCCGGCAGCAACGTGACTCTGAACATCTCTGAGAGCCTGC
  CTGAGAACTACAAACAACTAACCTGGTTTTATACTTTCGACCAGAAGATTGTAGAATGGG
  ATTCCAGAAAATCTAAGTACTTTGAATCCAAATTTAAAGGCAGGGTCAGACTTGATCCTC
  AGAGTGGCGCACTGTACATCTCTAAGGTCCAGAAAGAGGACAACAGCACCTACATCATGA
  GGGTGTTGAAAAAGACTGGGAATGAGCAAGAATGGAAGATCAAGCTGCAAGTGCTTGACC
  CTGTACCCAAGCCTGTCATCAAAATTGAGAAGATAGAAGACATGGATGACAACTGTTATC
  TGAAACTGTCATGTGTGATACCTGGCGAGTCTGTAAACTACACCTGGTATGGGGACAAAA
  GGCCCTTCCCAAAGGAGCTCCAGAACAGTGTGCTTGAAACCACCCTTATGCCACATAATT
  ACTCCAGGTGTTATACTTGCCAAGTCAGCAATTCTGTGAGCAGCAAGAATGGCACGGTCT
  GCCTCAGTCCACCCTGTACCCTGACACCGTCCTTTGGAGTAGAATGGATTGCAAGTTGGC
  TAGTGGTCACGGTGCACACCATTCTTGGGCCTGTACTTACCTGAGATGAGCTCTTTTAAA
  CTCAGCGAAACTTCAAGGCCAGNAAGATCTTGCCTGATGGNTGATCATGCTCCTCACCAG
  A
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001778 unedited
  GCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTCAGTTAATTGATAATTATATCAAATG
  TTTATTTTAAAAAATAATAAAACATTCACATAATGTTGTCACAATTTTGGGTGGGAAAAA
  AGCATGTGTATCTCTATATCTCTGTGTACTAGAAAACAACAAAGGGATATAAAATTAAAT
  AATAACCAGTATTTAAAAGTTAACTTGAAAATCCTCGTTGATAATTCAGCAGCATGCTTC
  TGGTCAGCCTATACAGTCTCTGTCCTGGTGAGGAGCATGATCACCAACAGGCAAGATCTT
  CTGGCCTTGAAGTTTCGCTTGAGTTAAAAGAGCTCATCTCAGGTAAGTAACAGGCCAAGA
  ATGGTGGGCACCGTGACCACTAGCCAACTTGCAATCCATTCTACTCCAAAGGACCGGGCC
  AGGGTACAGGGTGGACTGAGGCAGACCGTGCCATTCTTGCTGCTCACAGAATTGCTGACT
  TGGCAAGTATAACACCTGGAGTAATTATGTGGCATAAGGGTGGTTTCAAGCACACTGTTC
  TGGAGCTCCTTTGGGAAGGGCCTTTTGTCCCCATACCAGGTGTAGTTTACAGACTCGCCA
  GGTATCACACATGACAGTTTCAGAAACAGTTGTCATCCATGTCTTCTATCTTCTCAATTT
  TGATGACAGGCTTGGGTACAGGGTCAAGCACTTGCAGCTTGATCTTCCATTCTTGCTCAT
  TCCCAGNCTTTTTCAACACCCTCATGATGTAGGTGCCTGTGGCCTCTTCTGGACCTAGAG
  ATGACAGTGCGCACTCTGAGATCAGTCTGACCCTGCTTTAATTTGGATCAAAGACTAGAT
  TTCTTGATCCATCTCAATCTCTGTGCAAGTTAAACAGTTAATGTTGTAGTTTCAGCAGCT
  TTAGAAAGTAAAGTCCGTGCTGCGGAACACGGATATGCCCAAGACCTGATGTTGTACCGG
  AGGACCAGCCCCTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_001778
• Insert Size: 1120 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001778.2, NP_001769.2
• RefSeq Size: 1099 bp
• RefSeq ORF: 732 bp
• Locus ID: 962
• Cytogenetics: 1q23.3
• Domains: IG
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Natural killer cell mediated cytotoxicity
• Gene Summary: 'This gene encodes a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]'
  Transcript Variant: This variant (1) represents the shorter transcript and encodes the shorter protein (isoform 1).