CDC2L1 (CDK11B) (NM_001787) Human Untagged Clone

CAT#: SC119016

CDC2L1 (untagged)-Human cell division cycle 2-like 1 (PITSLRE proteins) (CDC2L1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CDK11B
• Synonyms: CDC2L1; CDK11; CDK11-p46; CDK11-p58; CDK11-p110; CLK-1; p58; p58CDC2L1; p58CLK-1; PITSLREA; PK58
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_001787 edited
  CGCGAATTCGGCACGAGGTTCTTCTCAGGCTCAGGGACCGGCCGCGGCCCCGTAGGGGTG
  AGTTCCGACTGGGCGGACCAGGTGTGGGAGCGCGACGAGAACTGCGCACCGAGGTCTTTC
  TTCCGAGCAGGCCTCGGAGCGGGGCGGACCCGGGCCCGGGGGCGAGCGACACCCTCGCTT
  CCGCGGACAGTCTCATCCCGCACGGAACTTTGGGTGGTGGAGGCGGCGGGTCCAAACGCT
  GTCTGGAGCCAACGTCTGCCAGGCTGAACCTCAAGTGTGCGGGACTGAACCCGAGGAAAT
  AGCCCAGTGCCCGGGTCAGGTGGCCTTGTTCGCGAGCACATCTCGGAGCATCTCCCCGGT
  CTCAAGGTGCAGCTGTCCAGTGTGCTAGTGGCTTCACGTAGTCCAAGCGGTCTTTCTAGC
  AGATTCTGACAGTAAAAGCAGTGTTTGATGAGTGGCAGGTCCTGAGTTAAGAGCCTTTAA
  ACGGATGATCTTTAATCCGCGATCGATACTATCACTGTTTTAACTCAAATGGGTGATGAA
  AAGGACTCTTGGAAAGTGAAAACTTTAGATGAAATTCTTCAGGAAAAGAAACGAAGGAAG
  GAACAAGAGGAGAAAGCAGAGATAAAACGCTTAAAAAATGTAAGCCATATTTTTTTAAGT
  AAGTGGTTTTCTTAAAGGAGATTTAATTTCTTTGCCCTCATTTTTCCATTAGAACAACGC
  TTCTTCGGTGAAGTTCTTTTGTACTTCCAAATGTCGCAGTCTGATGACCGGGATTCCAAG
  CGGGATTCCCTTGAGGAGGGGGAGCTGAGAGATCACTGCATGGAGATCACAATAAGGAAC
  TCCCCGTATAGAAGAGAAGACTCAATGGAAGACAGAGGAGAAGAAGATGATTCTTTGGCC
  ATCAAACCACCCCAGCAAATGTCTCGGAAAGAAAAAGTTCATCACAGAAAAGATGAAAAG
  AGAAAAGAAAAATGTAGGCATCATAGCCATTCAGCAGAAGGGGGGAAGCATGCTAGAGTG
  AAAGAAAGAGAGCACGAACGTCGGAAACGACATCGAGAAGAACAGGATAAAGCTCGCCGG
  GAATGGGAAAGACAGAAGAGAAGGGAAATGGCAAGGGAGCATTCCAGGAGAGAAAGGGAC
  CGCTTGGAGCAGTTAGAAAGGAAGCGGGAGCGGGAGCGCAAGATGCGGGAGCAGCAGAAG
  GAGCAGCGGGAGCAGAAGGAGCGCGAGCGGCGGGCGGAGGAGCGGCGCAAGGAGCGGGAG
  GCCCGCAGGGAAGTGTCTGCACATCACCGAACGATGAGAGAGGACTACAGCGACAAAGTG
  AAAGCCAGCCACTGGAGTCGCAGCCCGCCTCGGCCGCCGCGGGAGCGGTTCGAGTTGGGA
  GACGGCCGGAAGCCAGTAAAAGAAGAGAAAATGGAAGAAAGGGACCTGCTGTCCGACTTA
  CAGGACATCAGCGACAGCGAGAGGAAGACCAGCTCGGCCGAGTCCTCGTCAGCGGAATCA
  GGCTCAGGTTCTGAGGAAGAAGAGGAGGAGGAGGAAGAGGAGGAGGAGGAAGGGAGCACC
  AGTGAAGAATCAGAGGAGGAGGAGGAGGAAGAGGAAGAGGAGGAGGAGGAGACCGGCAGC
  AACTCTGAGGAGGCATCAGAGCAGTCTGCCGAAGAAGTAAGTGAGGAAGAAATGAGTGAA
  GATGAAGAACGAGAAAATGAAAACCACCTCTTGGTTGTTCCAGAGTCACGGTTCGACCGA
  GATTCCAGGGAGAGTGAAGAAGCAGAGGAAGAAGTGGGTGAGGGAACGCCGCAGAGCAGC
  GCCCTGACAGAGGGCAACTATGTGCCCGACTCCCCTGCCCTGTTGCCCATCGAGCTCAAG
  CAGGAGCTGCCCAAGTACCTGCCGGCCCTGCAGGGCTGCCGGAGCGTCGAGGAGTTCCAG
  TGCCTGAACAGGATCGAGGAGGGCACCTATGGAGTGGTCTACAGAGCAAAAGACAAGAAA
  ACAGATGAAATTGTGGCTCTAAAGCGGCTGAAGATGGAGAAGGAGAAGGAGGGCTTCCCG
  ATCACGTCTCTGAGGGAGATCAACACCATCCTCAAGGCCCAGCATCCCAACATCGTCACC
  GTTAGAGTGAGCATGGCCCCACCACGCCTGGCCCCGGGTGGAAGGCTTTTCCGACAGGGC
  CCCGTGCTGTCCTGGGGCCGGGTGCTTCCTACACTCTCCTGCACTTAGTGGAGCCCTTCA
  CAGACCACACAGAAGAGATTGTGGTGGGCAGCAACATGGACAAGATCTACATCGTGATGA
  ACTATGTGGAGCACGACCTCAAGAGCCTGATGGAGACCATGAAACAGCCCTTCCTGCCAG
  GGGAGGTGAAGACCCTGATGATCCAGCTGCTGCGGGGGGTGAAACACCTGCACGACAACT
  GGATCCTGCACCGTGACCTCAAGACGTCCAACCTGCTGCTGAGCCACGCCGGCATCCTCA
  AGGTGGGTGATTTTGGGCTGGCACGGGAGTACGGATCCCCTCTGAAGGCCTACACCCCGG
  TCGTGGTGACCCAGTGGTACCGCGCCCCAGAGCTGCTGCTTGGTGCCAAGGAATACTCCA
  CGGCCGTGGACATGTGGTCAGTGGGCTGCATCTTCGGGGAGCTGCTGACTCAGAAGCCTC
  TGTTCCCCGGGAATTCGGAAATCGATCAGATCAACAAAGTGTTCAAGGAGCTGGGGACCC
  CCAGTGAGAAAATCTGGCCCGGCTACAGCGAGCTCCCAGCAGTCAAGAAGATGACCTTCA
  GCGAGCACCCCTACAACAACCTCCGCAAGCGCTTCGGGGCTCTGCTCTCAGACCAGGGCT
  TCGACCTCATGAACAAGTTCCTGACCTACTTCCCCGGGAGGAGGATCAGCGCTGAGGACG
  GCCTCAAGCATGAGTATTTCCGCGAGACCCCCCTCCCCATCGACCCCTCCATGTTCCCCA
  CGTGGCCCGCCAAGAGCGAGCAGCAGCGTGTGAAGCGGGGCACCAGCCCGAGGCCCCCTG
  AGGGAGGCCTGGGCTACAGCCAGCTGGGTGACGACGACCTGAAGGAGACGGGCTTCCACC
  TTACCACCACGAACCAGGGGGCCTCTGCCGCGGGCCCCGGCTTCAGCCTCAAGTTCTGAA
  GGTCAGAGTGGACCCCGTCATGGGGAGAACTCAGCCGGGACCACAGGCGTGGCTACTGCG
  GCTGGAGCTGCGATGAGACTCGGAACTCCTCGTCTTACTTTGTGCTCCATGTTTTGTTTT
  TGTA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001787 unedited
  TTGTAATACGACTCACTATAGGGGCGGCCGCGATTCGGCACGAGGTTCTTCTCAGGCTCA
  GGGACCGGCCGCGGCCCCGTAGGGGTGAGTTCCGACTGGGCGGACCAGGTGTGGGAGCGC
  GACGAGAACTGCGCACCGAGGTCTTTCTTCCGAGCAGGCCTCGGAGCGGGGCGGACCCGG
  GCCCGGGGGCGAGCGACACCCTCGCTTCCGCGGACAGTCTCATCCCGCACGGAACTTTGG
  GTGGTGGAGGCGGCGGGTCCAAACGCTGTCTGGAGCCAACGTCTGCCAGGCTGAACCTCA
  AGTGTGCGGGACTGAACCCGAGGAAATAGCCCAGTGCCCGGGTCAGGTGGCCTTGTTCGC
  GAGCACATCTCGGAGCATCTCCCCGGTCTCAAGGTGCAGCTGTCCAGTGTGCTAGTGGCT
  TCACGTAGTCCAAGCGGTCTTTCTAGCAGATTCTGACAGTAAAAGCAGTGTTTGATGAGT
  GGCAGGTCCTGAGTTAAGAGCCTTTAAACGGATGATCTTTAATCCGCGATCGATACTATC
  ACTGTTTTAACTCAAATGGGTGATGAAAAGGACTCTTGGAAAGTGAAAACTTTAGATGAA
  ATTCTTCAGGAAAAGAAACGAAGGAAGGAACAAGAGGAGAAAGCAGAGATAAAACGCTTA
  AAAATGTAAGCCATATTTTTTTAAGTAAGTGGTTTTCTTAAAGGAGATTTAAATTTCTTG
  CCCTCATTNTTCCATTAGAACAANCGCTTNCTCGGTGAAGNTCCTTTTGTACTTNCCAAT
  GGTCGCAGNTCTGATGACCCGGGATTCCAAGCGGGGATTCCCTTGAGGAGGGGGGAGCTG
  AGAGACACTGCATGGGAGACACATAAGGAANNCTCCCGTATAGAAGAGAAGAACTCATGG
  GAGACAGAGGAGAAGAAGATGATTTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001787 unedited
  NNNTTTTCTNNGNNACGCGGNCCGCATTCTAGNGATCGATTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTCTTTTTTTTCCCCCCCACA
  ACAGGGAAAAATGATTTAATTCTCCAATTTTCCAACCCAAAATCCAAAAACAAAACCGGG
  GCCACAAATTAAAACAAGGGTTTCCAATTCTCATCCCACCCCCCGCCGCAATACCCCCCC
  CTGGGGCCCCGGCTGATTTCCCCCAAAGACGGGGCCCATTCTGACCTTAAAAACTTGAGG
  CTAAACCCGGGCCCCGGGGAAAAAGCCCCCTGTTTCGGGGGGGAAAGGGGGAAACCCCTC
  TCCTTTCGGTCTCTCTCCCCCCCCCGGCTGGGTCCCAGGCCTCCCCAAGGGGGCCCCGGG
  GCCGGACCCCCCCTTCAAACCTTAACGCCTCCTAATAGGCTCCCCAATTTTTAAATAATG
  AAGTATCATTCGCCTCACGCCAGGACCGACCCCGCCCTTATTTGATTCCCCGCCTCCCGA
  TAGAACCAGTCCCGTGGACTTACTCGACGCGACCGACACATAAATACATAAGGATCCCCC
  AATTTTCTATCAGTATCTCGCTTCACCGCAACCCTCTCTAGATGGAACGGGGGCAAGCTC
  ACGGGAGGCAGCGGCCCTCCCGGCCGCCGAACGATGCCGCCACACTCGCCGGATAGATTT
  CCCCCACTAGACGACATAAAAAAACAAATAACGACCCAAACCTCACTAACCACATCTGAA
  TCCGCACCGTACCATAATCCGTAATAGAAACGAAACGACAAGAGTTGTGTGCTCGTCTGG
  GTACGGTGTCTGTCCCCTTGTCCAGTCTACCCCTCACCCCGATACCTAAGACGTGACACA
  CACACTAGCTCACATCGCTACCCTACGCCAACACGCCCCG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_001787
• Insert Size: 3700 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001787.1, NP_001778.1
• RefSeq Size: 2525 bp
• RefSeq ORF: 2388 bp
• Locus ID: 984
• Cytogenetics: 1p36.33
• Domains: pkinase, TyrKc, S_TKc
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: 'This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]'
  Transcript Variant: This variant (1) encodes the longest isoform (1).