IGFBP7 (NM_001553) Human Untagged Clone

CAT#: SC119176

IGFBP7 (untagged)-Human insulin-like growth factor binding protein 7 (IGFBP7)


  "NM_001553" in other vectors (6)

Reconstitution Protocol

USD 310.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol IGFBP7
Synonyms AGM; FSTL2; IBP-7; IGFBP-7; IGFBP-7v; IGFBPRP1; MAC25; PSF; RAMSVPS; TAF
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_001553 edited
GAATTCGGCACGAGGCCGCTGCCACCGCACCCCGCCATGGAGCGGCCGTCGCTGCGCGCC
CTGCTCCTCGGCGCCGCTGGGCTGCTGCTCCTGCTCCTGCCCCTCTCCTCTTCCTCCTCT
TCGGACACCTGCGGCCCCTGCGAGCCGGCCTCCTGCCCGCCCCTGCCCCCGCTGGGCTGC
CTGCTGGGCGAGACCCGCGACGCGTGCGGCTGCTGCCCTATGTGCGCCCGCGGCGAGGGC
GAGCCGTGCGGGGGTGGCGGCGCCGGCAGGGGGTACTGCGCGCCGGGCATGGAGTGCGTG
AAGAGCCGCAAGAGGCGGAAGGGTAAAGCCGGGGCAGCAGCCGGCGGTCCGGGTGTAAGC
GGCGTGTGCGTGTGCAAGAGCCGCTACCCGGTGTGCGGCAGCGACGGCACCACCTACCCG
AGCGGCTGCCAGCTGCGCGCCGCCAGCCAGAGGGCCGAGAGCCGCGGGGAGAAGGCCATC
ACCCAGGTCAGCAAGGGCACCTGCGAGCAAGGTCCTTCCATAGTGACGCCCCCCAAGGAC
ATCTGGAATGTCACTGGTGCCCAGGTGTACTTGAGCTGTGAGGTCATCGGAATCCCGACA
CCTGTCCTCATCTGGAACAAGGTAAAAAGGGGTCACTATGGAGTTCAAAGGACAGAACTC
CTGCCTGGTGACCGGGACAACCTGGCCATTCAGACCCGGGGTGGCCCAGAAAAGCATGAA
GTAACTGGCTGGGTGCTGGTATCTCCTCTAAGTAAGGAAGATGCTGGAGAATATGAGTGC
CATGCATCCAATTCCCAAGGACAGGCTTCAGCATCAGCAAAAATTACAGTGGTTGATGCC
TTACATGAAATACCAGTGAAAAAAGGTGAAGGTGCCGAGCTATAAACCTCCAGAATATTA
TTAGTCTGCATGGTTAAAAGTAGTCATGGATAACTACATTACCTGTTCTTGCCTAATAAG
TTTCTTTTAATCCAATCCACTAACACTTTAGTTATATTCACTGGTTTTACACAGAGAAAT
ACAAAATAAAGATCACACATCAAGACTATCTACAAAAATTTATTATATATTTACAGAAGA
AAAGCATGCATATCATTAAACAAATAAAATACTTTTTATCACAACACAAAAAAAAAAAAA
AAAAAAAACTCGAC
>OriGene 5' read for NM_001553 unedited
NGGGTTTTAGGATTTGTNATCCGACTTCACTATNAGGNNCGGCCGCGCAATTCGGCACGA
GGCCGCTGCCACCGCACCCCGCCATGGAGCGGCCGTCGCTGCGCGCCCTGCTCCTCGGCG
CCGCTGGGCTGCTGCTCCTGCTCCTGCCCCTCTCCTCTTCCTCCTCTTCGGACACCTGCG
GCCCCTGCGAGCCGGCCTCCTGCCCGCCCCTGCCCCCGCTGGGCTGCCTGCTGGGCGAGA
CCCGCGACGCGTGCGGCTGCTGCCCTATGTGCGCCCGCGGCGAGGGCGAGCCGTGCGGGG
GTGGCGGCGCCGGCAGGGGGTACTGCGCGCCGGGCATGGAGTGCGTGAAGAGCCGCAAGA
GGCGGAAGGGTAAAGCCGGGGCAGCAGCCGGCGGTCCGGGTGTAAGCGGCGTGTGCGTGT
GCAAGAGCCGCTACCCGGTGTGCGGCAGCGACGGCACCACCTACCCGAGCGGCTGCCAGC
TGCGCGCCGCCAGCCAGAGGGCCGAGAGCCGCGGGGAGAAGGCCATCACCCAGGTCAGCA
AGGGCACCTGCGAGCAAGGTCCTTCCATAGTGACGCCCCCCAAGGACATCTGGAATGTCA
CTGGTGCCCAGGTGTACTTGAGCTGTGAGGTCATCGGAATCCCGACACCTGTCCTCATCT
GGAACAAGGTAAAAAGGGGTCACTATGGAGTTCAAAGGACAGAACTCCTGCCTGGTGACC
GGGACAACCCTGCCATTCAGACCCGGGGTGGCCCCAGAAAGCATGAAGTAACTGGCTGGG
TGCTGGTATCTCCTCTAAGTAGGAAGATGCTGNAGAATATGAGTGCCATGCATCCAATTN
CCAAGGACAGGCTTCAGCATCAGCAAAAATACAGTGGGTGATGCCCTACATGAATAACAG
TGAAAAAAGTGAAAGTGCCCGA
>OriGene 3' read for NM_001553 unedited
TTTAACGGCCTCTATGTACCGCGGCCGCTTTCNAAGATCGGTTTTTTCCTTTTTTTTTTT
TTTGTGTTGTGATAAAAAGTTTTTATTTGTTTAATGATATGCATGCTTTTCTTCTGTAAA
TATATAATAAATTTTTGTAGATAGTCTTGATGTGTGATCTTTATTTTGTATTTCTCTGTG
TAAAACCAGTGAATATAACTAAAGTGTTAGTGGATTGGATTAAAAGAAACTTATTAGGCA
AGAACAGGTAATGTAGTTATCCATGACTACTTTTAACCATGCAGACTAATAATATTCTGG
AGGTTTATAGCTCGGCACCTTCACCTTTTTTCACTGGTATTTCATGTAAGGCATCAACCA
CTGTAATTTTTGCTGATGCTGAAGCCTGTCCTTGGGAATTGGATGCATGGCACTCATATT
CTCCAGCATCTTCCTTACTTAGAGGAGATACCAGCACCCAGCCAGTTACTTCATGCTTTT
CTGGGCCACCCCGGGTCTGAATGGCCAGGTTGTCCCGGTCACCAAGCAGGAGTTCTGTCC
TTTGAACTCCATAGTGACCCCTTTTTACCTTGTTCCAGATGAAGACAGGTGTCGGGATTC
CGATGACCTCACAGCTCAAGTACACCTGGGCACCAGTGACATTCCAGATGTCCTTGGGGG
GCGTCACTATGGAAAGACCTTGCTCGCAAGTGCCCTTGCTGACCTGGGTGATGGCCTTCT
CCCCGCGGCTCTCGGCCCTCTGGCTGGCGGCGCGCATCTGGCAGCCGCTCGGTAAGTGGG
TGGCCCGTCGCTGCCGCACACCGGGGTAGCGGNCTCTTGCACACGCACACGCCGCTTACA
CCCTNACCGCCGGG
Restriction Sites NotI-NotI     
ACCN NM_001553
Insert Size 1200 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_001553.1, NP_001544.1
RefSeq Size 1124 bp
RefSeq ORF 849 bp
Locus ID 3490
Cytogenetics 4q12
Domains IB, kazal, IG
Protein Families Secreted Protein
Gene Summary 'This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307). [provided by RefSeq, Dec 2011]'
Transcript Variant: This variant (1) represents the predominant transcript, and encodes the longer isoform (1).

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