Glycoprotein 2 (GP2) (NM_001502) Human Untagged Clone

CAT#: SC119209

GP2 (untagged)-Human glycoprotein 2 (zymogen granule membrane) (GP2), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GP2
• Synonyms: ZAP75
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001502, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCCTCACCTTATGGAAAGGATGGTGGGCTCTGGCCTCCTGTGGCTGGCCTTGGTCTCCTGCATTCTGA
  CCCAGGCATCTGCAGTGCAGCGAGGTTATGGAAACCCCATTGAAGCCAGTTCGTATGGGCTGGACCTGGA
  CTGCGGAGCTCCTGGCACCCCAGAGGCTCATGTCTGTTTTGACCCCTGTCAGAATTACACCCTCCTGGAT
  GAACCCTTCCGAAGCACAGAGAACTCAGCAGGGTCCCAGGGGTGCGATAAAAACATGAGCGGCTGGTACC
  GCTTTGTAGGGGAAGGAGGAGTAAGGATGTCGGAGACCTGTGTCCAGGTGCACCGATGCCAGACAGACGC
  TCCCATGTGGCTGAATGGGACCCACCCTGCCCTTGGGGATGGCATCACCAACCACACTGCCTGTGCCCAT
  TGGAGTGGCAACTGCTGTTTCTGGAAAACAGAGGTGCTGGTGAAGGCCTGCCCAGGCGGGTACCATGTGT
  ACCGGTTGGAAGGCACTCCCTGGTGTAATCTGAGATACTGCACAGACCCATCCACTGTGGAGGACAAGTG
  TGAGAAGGCCTGCCGCCCCGAGGAGGAGTGCCTTGCCCTCAACAGCACCTGGGGCTGTTTCTGCAGACAG
  GACCTCAATAGTTCTGATGTCCACAGTTTGCAGCCTCAGCTAGACTGTGGGCCCAGGGAGATCAAGGTGA
  AGGTGGACAAATGTTTGCTGGGAGGCCTGGGTTTGGGGGAGGAGGTCATTGCCTACCTGCGAGACCCAAA
  CTGCAGCAGCATCTTGCAGACAGAGGAGAGGAACTGGGTATCTGTGACCAGCCCCGTCCAGGCTAGTGCC
  TGCAGGAACATTCTGGAGAGAAATCAAACCCATGCCATCTACAAAAACACCCTCTCCTTGGTCAATGATT
  TCATCATCAGAGACACCATCCTCAACATCAACTTCCAATGTGCCTACCCACTGGACATGAAAGTCAGCCT
  CCAAGCTGCCTTGCAGCCCATTGTAAGTTCCCTGAACGTCAGTGTGGACGGGAATGGAGAGTTCATTGTC
  AGGATGGCCCTCTTCCAAGACCAGAACTACACGAATCCTTACGAAGGGGATGCAGTTGAACTGTCTGTTG
  AGTCCGTGCTGTATGTGGGTGCCATCTTGGAACAAGGGGACACCTCCCGGTTTAACCTGGTGTTGAGGAA
  CTGCTATGCCACCCCCACTGAAGACAAGGCTGACCTTGTGAAGTATTTCATCATCAGAAACAGCTGCTCA
  AATCAACGTGATTCCACCATCCACGTGGAGGAGAATGGGCAGTCCTCGGAAAGCCGGTTCTCAGTTCAGA
  TGTTCATGTTTGCTGGACATTATGACCTAGTTTTCCTGCATTGTGAGATTCATCTCTGTGATTCTCTTAA
  TGAACAGTGCCAGCCTTCTTGCTCAAGAAGTCAAGTCCGCAGTGAAGTACCGGCCATCGACCTAGCCCGG
  GTTCTAGATTTGGGGCCCATCACTCGGAGAGGTGCACAGTCTCCCGGTGTCATGAATGGAACCCCTAGCA
  CTGCAGGGTTCCTGGTGGCCTGGCCTATGGTCCTCCTGACTGTCCTCCTGGCTTGGCTGTTCTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001502 unedited
  GAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGCCAGAGGAGGAACGCTT
  TGTGTTCTCATCGGAGCTGCATGGGAAGTCTGCATACAGCAAAGTGACCTGCATGCCTCA
  CCTTATGGAAAGGATGGTGGGCTCTGGCCTCCTGTGGCTGGCCTTGGTCTCCTGCATTCT
  GACCCAGGCATCTGCAGTGCAGCGAGGTTATGGAAACCCCATTGAAGCCAGTTCGTATGG
  GCTGGACCTGGACTGCGGAGCTCCTGGCACCCCAGAGGCTCATGTCTGTTTTGACCCCTG
  TCAGAATTACACCCTCCTGGATGAACCCTTCCGAAGCACAGAGAACTCAGCAGGGTCCCA
  GGGGTGCGATAAAAACATGAGCGGCTGGTACCGCTTTGTAGGGGAAGGAGGAGTAAGGAT
  GTCGGAGACCTGTGTCCAGGTGCACCGATGCCAGACAGACGCTCCCATGTGGCTGAATGG
  GACCCACCCTGCCCTTGGGGATGGCATCACCAACCACACTGCCTGTGCCCATTGGAGTGG
  CAACTGCTGTTTCTGGAAAACAGAGGTGCTGGTGAAGGCCTGCCCAGGCGGGTACCATGT
  GTACCGGTTGGAAGGCACTCCCTGGTGTAATCTGAGATACTGCACAGACCCATCCACTGT
  GGAGGACAAGTGTGAGAAGGCCTGCCGCCCCGNAGAGGAGTGCCTTGCCCTCACAGCACC
  TGGGGCTGTTTCTGCAGACAGACCCTCATAGTTCTGATGTCCACAGTTTGCAGCCTCAGC
  TAGACTGTGGGCCCANNGAGATCAAGGTGAAGGTGGACCNAATGTTGCTGGGAGGCCCTG
  NGTTTGNGGGGAGNAGTCATNGCCTACCCTGCGAGACCAACTGCAGCAGCATCTTGCAGA
  CAGAGAGAAGAACTGGGTATCTGTGACAGCCCCGTCCAGCTAGTGCTGCG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001502 unedited
  GCAATTTAAAGTCGAGTTNTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGC
  TGAAACAAAAAATTGCTTTGTTGCCCAAGCTGGAGAGCAAAGGGACAATGTTAACTTACT
  GGAAACTCCACCCCCTGAGTTCGAGCAATTTTCCTGCCTTGGGCTTCCGAGTACCTGGGA
  TTACAGGGGCCTGGCACCATGCCTGGGTAATTTTTGGATTTTTAGGGGAGACGGAGTTTC
  AGCATTTTGGCCAGGCTGATTTTGAACTGGTGACCTCAGGGGATCCACCTGCCTCAGGCT
  TCCAAAATGCTGGGATTACAGGCTTGAGCCACTGGCCCCAGCCCAGAGTTTTAAAGAAAG
  GGAAAGGTCTTACCTTTTCCTAACCTAAACTGGACTTGAGTCTGGTAATACCAAACCTCT
  GTGAATTGGAGTGGAAAGCAGAAATGCTAAAGGGAGCCATTGCCCAAGGGAAGAACACAA
  ACTTCAAGGCCAGATGCTCAACGGAGCTCTTAGAACATCCAACCCCCGAGGACAGTCGAG
  AGGACCATAGGCCATGCCACCAGGAACCCTGCACCGCTAAGGGGTCCATTCATGACACCG
  GGAGACTGTGCACCTCTCCGAGTGATGGGCCCCAAATCTAAAACCCGGGCTACGGCCAAG
  GGCCGGAGCTTACTGCGGACTTGACTTCTTGAGCCAAGAGGCTGGCACCTGTTCATTAAG
  AGAATCACAAAGATGAAATTCACATTGCAGGAAAACTAGGTACATATGTCCACGGAACAT
  GACATTTGAACTGGAACCCGGGTTCCGAGGACTGCCATTCTCCTCCTTGGAAGGGGAAAA
  CCGTAATTAGACACTGTTCTGATAAGAAAAATAAAAAGGGCACCCTGCTTCATGGGGGGG
  GGATAGGTCCTCACCCCGTTAACCGGGAGGGGCCCGTGTTCCGATGCCCCCCTACACACG
  GCTCAAGGACATCACAGTTCCCCTCCCAGGAAGGAG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_001502
• Insert Size: 2440 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001502.2, NP_001493.2
• RefSeq Size: 2439 bp
• RefSeq ORF: 1605 bp
• Locus ID: 2813
• Cytogenetics: 16p12.3
• Domains: zona_pellucida
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Gene Summary: 'This gene encodes an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. The encoded protein binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]'
  Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. The resulting protein (isoform 2, also known as alpha) is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.