FOXO3 (NM_001455) Human Untagged Clone

CAT#: SC119227

FOXO3 (untagged)-Human forkhead box O3 (FOXO3), transcript variant 1


  "NM_001455" in other vectors (6)

Reconstitution Protocol

USD 310.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol FOXO3
Synonyms AF6q21; FKHRL1; FKHRL1P2; FOXO2; FOXO3A
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_001455 edited
CGGAGCCTTCGCGGCGTCCACGTCCCTCCCCCGCTGCACCCCGCCCCGGCGCGAGAGGAG
AGCGCGAGAGCCCCAGCCGCGGGCGGGCGGGCGGCGAAGATGGCAGAGGCACCGGCTTCC
CCGGCCCCGCTCTCTCCGCTCGAAGTGGAGCTGGACCCGGAGTTCGAGCCCCAGAGCCGT
CCGCGATCCTGTACGTGGCCCCTGCAAAGGCCGGAGCTCCAAGCGAGCCCTGCCAAGCCC
TCGGGGGAGACGGCCGCCGACTCCATGATCCCCGAGGAGGAGGACGATGAAGACGACGAG
GACGGCGGGGGACGGGCCGGCTCGGCCATGGCGATCGGCGGCGGCGGCGGGAGCGGCACG
CTGGGCTCCGGGCTGCTCCTTGAGGACTCGGCCCGGGTGCTGGCACCCGGAGGGCAAGAC
CCCGGGTCTGGGCCAGCCACCGCGGCGGGCGGGCTGAGCGGGGGTACACAGGCGCTGCTG
CAGCCTCAGCAACCGCTGCCACCGCCGCAGCCGGGGGCGGCTGGGGGCTCCGGGCAGCCG
AGGAAATGTTCGTCGCGGCGGAACGCCTGGGGAAACCTGTCCTACGCGGACCTGATCACC
CGCGCCATCGAGAGCTCCCCGGACAAACGGCTCACTCTGTCCCAGATCTACGAGTGGATG
GTGCGTTGCGTGCCCTACTTCAAGGATAAGGGCGACAGCAACAGCTCTGCCGGCTGGAAG
AACTCCATCCGGCACAACCTGTCACTGCATAGTCGATTCATGCGGGTCCAGAATGAGGGA
ACTGGCAAGAGCTCTTGGTGGATCATCAACCCTGATGGGGGGAAGAGCGGAAAAGCCCCC
CGGCGGCGGGCTGTCTCCATGGACAATAGCAACAAGTATACCAAGAGCCGTGGCCGCGCA
GCCAAGAAGAAGGCAGCCCTGCAGACAGCCCCCGAATCAGCTGACGACAGTCCCTCCCAG
CTCTCCAAGTGGCCTGGCAGCCCCACGTCACGCAGCAGTGATGAGCTGGATGCGTGGACG
GACTTCCGTTCACGCACCAATTCTAACGCCAGCACAGTCAGTGGCCGCCTGTCGCCCATC
ATGGCAAGCACAGAGTTGGATGAAGTCCAGGACGATGATGCGCCTCTCTCGCCCATGCTC
TACAGCAGCTCAGCCAGCCTGTCACCTTCAGTAAGCAAGCCGTGCACGGTGGAACTGCCA
CGGCTGACTGATATGGCAGGCACCATGAATCTGAATGATGGGCTGACTGAAAACCTCATG
GACGACCTGCTGGATAACATCACGCTCCCGCCATCCCAGCCATCGCCCACTGGGGGACTC
ATGCAGCGGAGCTCTAGCTTCCCGTATACCACCAAGGGCTCGGGCCTGGGCTCCCCAACC
AGCTCCTTTAACAGCACGGTGTTCGGACCTTCATCTCTGAACTCCCTACGCCAGTCTCCC
ATGCAGACCATCCAAGAGAACAAGCCAGCTACCTTCTCTTCCATGTCACACTATGGTAAC
CAGACACTCCAGGACCTGCTCACTTCGGACTCACTTAGCCACAGCGATGTCATGATGACA
CAGTCGGACCCCTTGATGTCTCAGGCCAGCACCGCTGTGTCTGCCCAGAATTCCCGCCGG
AACGTGATGCTTCGCAATGATCCGATGATGTCCTTTGCTGCCCAGCCTAACCAGGGAAGT
TTGGTCAATCAGAACTTGCTCCACCACCAGCACCAAACCCAGGGCGCTCTTGGTGGCAGC
CGTGCCTTGTCGAATTCTGTCAGCAACATGGGCTTGAGTGAGTCCAGCAGCCTTGGGTCA
GCCAAACACCAGCAGCAGTCTCCTGTCAGCCAGTCTATGCAAACCCTCTCGGACTCTCTC
TCAGGCTCCTCCTTGTACTCAACTAGTGCAAACCTGCCCGTCATGGGCCATGAGAAGTTC
CCCAGCGACTTGGACCTGGACATGTTCAATGGGAGCTTGGAATGTGACATGGAGTCCATT
ATCCGTAGTGAACTCATGGATGCTGATGGGTTGGATTTTAACTTTGATTCCCTCATCTCC
ACACAGAATGTTGTTGGTTTGAACGTGGGGAACTTCACTGGTGCTAAGCAGGCCTCATCT
CAGAGCTGGGTGCCAGGCTGAAGGATCACTGAGGAAGGGGAAGTGGGCAAAGCAGACCCT
CAAACTGACACAAGACCTACAGAGAAAACCCTTTGCCAAATCTGCTCTCAGCAAGTGGAC
A
>OriGene 5' read for NM_001455 unedited
CGGGGCCCCACCTCCCCCTTCCCCCCCGGTTCAGAATTGTNATACAACTCATATAGGCGG
CCGCGNAATTCGCACGAGGGGAGTGGCGGCAGCGGGCGAGGACTCGCCGAGGACGGGGCT
CCGGCCCGGGATAACCAACTCTCCTTCTCTCTTCTTTGGTGCTTCCCCAGGCGGCGGCGG
CGGCGCCCGGGAGCCGGAGCCTTCGCGGCGTCCACGTCCCTCCCCCGCTGCACCCCGCCC
CGGCGCGAGAGGAGAGCGCGAGAGCCCCAGCCGCGGGCGGGCGGGCGGCGAAGATGGCAG
AGGCACCGGCTTCCCCGGCCCCGCTCTCTCCGCTCGAAGTGGAGCTGGACCCGGAGTTCG
AGCCCCAGAGCCGTCCGCGATCCTGTACGTGGCCCCTGCAAAGGCCGGAGCTCCAAGCGA
GCCCTGCCAAGCCCTCGGGGGAGACGGCCGCCGACTCCATGATCCCCGAGGAGGAGGACG
ATGAAGACGACGAGGACGGCGGNGGACGGGCCGGCTCGGCCATGGCGATCGGCGGCGGCG
GCGGGAGCGGCACGCTGGGCTCCGGGCTGCTCCTTGAGGACTCGGCCCGGGTGCTGGCAC
CCCGGAGGCAAGACCCCGGGTCTGGGCCAGCCACCGCNGCGGGCGGGCTGAGCGGGGTAC
ACANGCGCTGCTGCAGCCTCAGCACCGCTGCCACCGNCGCCACCGGGGGCGGCTGGGGGC
TTCCGGCAGCCGAGGAAAGGTTCGTCGCCGCGGAAACGCCTGGGAAAACTGTNCTACGCG
GACCTGATCCCCCGCGCCATCCAGAGCTCCCCGGGACAACCGGTNACTCTGGCCCAAATC
TACCAAGGGATGTGGCCGTTGCGTGCCTCAATTAAGGAATAAGGGCAACAGAAACAGATT
TGCCGGGTGGAAGGACTCCATTCGGAACAACCTGAACTGAATTAACCAATCCTGCCGGGT
CCCAAAGAAGGGAACTGGCAAAAGCCCTTGGGGAGACATAACCCCTGAGGG
>OriGene 3' read for NM_001455 unedited
CTAGAGGCAGGGCGTCACAGGGAATGCCACCCGGACATCTGTGGCAGTAAAAGCTCTGAC
CGAGGCCGCAATCTAAACCCAAGCCTCCAAAAAATCCTCCTCACTACTTCTGGAATAGCT
CACCAGACAACGAAACCCTTTGGCGACGTTTGAAAAAGAAAGAAAAGCAGCCCTGGTGCC
TTTACTGAAAAGAACAGGTCCGAGTTAGTAACCGGCAGACCAACACTGTTCACATTACCT
GAGGACCCTGACAGGAAATCACAGGCCCTACTGATCTGGCACCCGTAGACTTGGCGCTGG
GGTCCCGTCCAAAGATCACCCTGACTCAAAACCGGAAACACACTGGGCCGGACCCTGTGC
TCCACTCCTTTTGCCTATGCACGGTTCTGGCCTGGACGGGTGCACATAGCAAACAATTGT
GCCATTGTTCAATTTTTAGAAAAGGATAATTCCCTCCCAAACAAAAAAAGAAAGAAAATC
CCCCCTTAGTTGATGCAATTTGTGAGCTTATGGAGTTCCATGCGCTCAAAAGCTTGTGAT
GCTCGAACCCGGAATGGTAACTGGCACAACATTTTCTTTCTGTTTTTAAATTTGCTAGGG
GAAGGACGGTTAACATTTTAACAGAAAAATACCGCAGTTATGCGTGTGAAAAACTCAGAA
GCCCAAGGAAAACAAACGCCGGAACAACGCTTAAAACGTCCCATAAACCATCGCAATTTC
AAAACACCACAGAATGGCCGACGGGGGCTCACGGTGGGCTCTGAAATGAGGTGGGTGGTG
CCCAAGGGTCCTGTCCTCCACTGGCAGGCGGCTCACCCCCGGTCAAGG
Restriction Sites NotI-NotI     
ACCN NM_001455
Insert Size 3250 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation TrueClone.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_001455.2, NP_001446.1
RefSeq Size 3338 bp
RefSeq ORF 2022 bp
Locus ID 2309
Cytogenetics 6q21
Domains FH
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Chemokine signaling pathway, Endometrial cancer, Neurotrophin signaling pathway, Non-small cell lung cancer
Gene Summary 'This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]'
Transcript Variant: This variant (1) differs in the 5' end and represents the longer transcript compared to variant 2. Both variants encode the same protein.

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