FMO5 (NM_001461) Human Untagged Clone

CAT#: SC119228

FMO5 (untagged)-Human flavin containing monooxygenase 5 (FMO5), transcript variant 1


  "NM_001461" in other vectors (4)

Reconstitution Protocol

USD 900.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol FMO5
Synonyms flavin containing monooxygenase 5; OTTHUMP00000016306
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>NCBI ORF sequence for NM_001461, the custom clone sequence may differ by one or more nucleotides


ATGACTAAGAAAAGAATTGCTGTGATTGGGGGAGGAGTGAGCGGGCTCTCTTCCATCAAGTGCTGCGTAG
AAGAAGGCTTGGAACCTGTCTGCTTTGAAAGGACTGATGACATCGGAGGGCTCTGGAGGTTCCAGGAAAA
TCCTGAAGAAGGAAGGGCCAGTATTTACAAATCAGTGATCATCAATACTTCTAAAGAGATGATGTGCTTC
AGTGACTATCCAATCCCAGATCATTATCCCAACTTCATGCATAATGCCCAGGTCCTGGAGTATTTCAGGA
TGTATGCCAAAGAATTTGACCTTCTAAAGTATATTCGATTTAAGACCACTGTGTGCAGTGTGAAGAAGCA
GCCTGATTTTGCCACTTCAGGCCAATGGGAAGTGGTCACTGAATCTGAAGGGAAAAAGGAGATGAATGTC
TTTGATGGAGTCATGGTTTGCACTGGCCATCACACCAATGCTCATCTACCTCTGGAAAGCTTCCCTGGAA
TTGAGAAGTTCAAAGGGCAGTACTTCCACAGTCGAGACTATAAGAACCCAGAGGGATTCACTGGAAAGAG
AGTCATTATAATTGGCATTGGGAATTCTGGAGGGGATCTGGCTGTAGAGATTAGCCAAACAGCCAAGCAG
GTTTTCCTCAGCACCAGGAGAGGGGCTTGGATCCTGAATCGTGTAGGGGACTACGGATATCCTGCTGATG
TGTTGTTCTCTTCTCGACTTACACATTTTATATGGAAGATCTGTGGCCAATCATTAGCAAACAAATATTT
GGAAAAAAAGATAAACCAAAGGTTTGACCATGAAATGTTTGGCCTGAAGCCTAAACACAGAGCTCTGAGT
CAGCATCCAACCTTAAATGATGACCTGCCAAATCGTATCATTTCTGGCTTGGTGAAAGTGAAAGGAAATG
TGAAGGAATTCACGGAGACAGCTGCCATATTTGAGGATGGCTCCAGGGAGGATGACATTGATGCTGTTAT
CTTTGCCACAGGCTATAGCTTTGACTTTCCATTTCTGGAAGATTCCGTCAAAGTGGTCAAAAACAAGATA
TCCCTGTATAAAAAGGTCTTCCCTCCTAACCTGGAAAGGCCAACTCTTGCAATCATAGGCTTGATTCAGC
CCTTAGGAGCCATTATGCCCATTTCAGAGCTCCAAGGACGCTGGGCCACTCAGGTATTTAAAGGTCTAAA
GACATTGCCCTCACAGAGTGAAATGATGGCAGAAATATCTAAAGCTCAAGAGGAAATTGACAAAAGGTAT
GTGGAGAGCCAACGCCATACCATTCAGGGAGACTACATAGATACCATGGAAGAGCTTGCTGATTTGGTGG
GGGTCAGGCCCAATCTGCTGTCTCTGGCCTTCACTGACCCCAAGCTGGCATTACACTTATTACTGGGACC
CTGCACTCCAATCCACTATCGTGTACAGGGCCCTGGAAAGTGGGATGGGGCTCGAAAAGCTATCCTCACC
ACAGATGATCGCATCAGGAAGCCTCTGATGACAAGAGTAGTTGAAAGGAGTAGTTCTATGACTTCAACAA
TGACAATAGGCAAGTTTATGCTAGCTCTTGCCTTCTTTGCTATAATTATAGCTTACTTCTAG


>OriGene 5' read for NM_001461 unedited
GCGAATTCGGCACGAGGTTGAGTCTCCTCCAGATCGCAGCTGAAGGATCTGTTGAGCGCT
TCAGGAAAGGCGGACAGGCGACACTAACAGGTGAAGATCTCGGGAGACCATGACTAAGAA
AAGAATTGCTGTGATTGGGGGAGGAGTGAGCGGGCTCTCTTCCATCAAGTGCTGCGTAGA
AGAAGGCTTGGAACCTGTCTGCTTTGAAAGGACTGATGACATCGGAGGGCTCTGGAGGTT
CCAGGAAAATCCTGAAGAAGGAAGGGCCAGTATTTACAAATCAGTGATCATCAATACTTC
TAAAGAGATGATGTGCTTCAGTGACTATCCAATCCCAGATCATTATCCCAACTTCATGCA
TAATGCCCAGGTCCTGGAGTATTTCAGGATGTATGCCAAAGAATTTGACCTTCTAAAGTA
TATTCGATTTAAGACCACTGTGTGCAGTGTGAAGAAGCAGCCTGATTTTGCCACTTCAGG
CCAATGGGAAGTGGTCACTGAATCTGAAGGGAAAAAGGAGATGAATGTCTTTGATGGAGT
CATGGTTTGCACTGGCCATCACACCAATGCTCATCTACCTCTGGAAAGCTTCCCTGGAAT
TGAGAAGTTCAAAGGGCAGTACTTCCACAGTCGAGACTATAAGAACCCAGAGGGATTCAC
TGGAAAGAGAGTCATTATAATTGGCATTGGGAATTCTGGAGGGGATCTGGCTGTAGAGAT
TANCCAAN
>OriGene 3' genomic read for NM_001461 unedited
ACTTGAACCGCGCCGCAATCTATAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTAAACCAAAAGGCATACTTTATTAATATTCCCTTAATTTTTA
CTTAAAGTTCTTTTTCGGGGGCGGGAGCCCCTCCAGGATACTACATTACATTTAAAGGGT
ATGGCCCCTTAGGCCCCTTTATTCCGGGACAATTTCTAAAACTTTTTTTGGGGAAGAACT
TGACAGGGGGGGGGGAGCCAGGTTTTTGTAAAATATTCTCCAACTGGGGTTGGGCGGAGG
TTTTTCTCAGGGGAAAACTGCATTATGGCTTTCGAGAGGAATACCCCCGAGAGGGAAAGG
GGCCTTTTAATCACTTCATCTCAAAGGAACAACCTATCAGGGGGACCCCACCCGTGGGCC
GGGGCATCCCGTACCCCCCTCCCGCCCGAGCGCCCCTATCCACCCCCCCCCCACTCAGCA
ACCTGCCCCCACCACCCTTTCAGCCAGGCCCTCCTCAGGCCGGCAGCCGCACTTTCGCGG
TCCCCCTTCTGACTGGACGGTGCCGGCTCCCCCCCCCCCTCTCTCCGACCAGCCCCAACT
GCCGGACGCGAGCCCCCTCCCCCCATAGCTACAATTTGGTGTCGCCACCCGCCCCCCACA
GTTGCCCCGCCCCCCGCCGCGCCCACCCCCACGCATCCCCGCCACGCCCAGCGGTAGCCG
CACGCCGAGGGAGTAGAGCCGAGTCTGGCGTCCCCGTGCACGCACCCCCCCTCGCGAGGC
TGCGCCCGGGGTGACCCCCCCCGCCCACCCGCCGTCAGGTCGCCGGCATACGCTTCCCCC
CCCCCCACACCCCTCGCCCCCCTCCACCCCGCGCCCGCCATCCCCCACTCGTCCGCATCC
GCTCCGCCCCCGCTGCCGTCTCGTGTCCCGCGCCGCCCGCCGAGCGGACCTCCTCGCGAT
TATGGCGCACCCCTCGCTTCGGCTTCTCCCGTCTCTTCCCCCCCG
Restriction Sites NotI-NotI     
ACCN NM_001461
Insert Size 4700 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_001461.1, NP_001452.1
RefSeq Size 2326 bp
RefSeq ORF 1602 bp
Locus ID 2330
Cytogenetics 1q21.1
Domains FMO-like
Protein Families Druggable Genome, Transmembrane
Protein Pathways Drug metabolism - cytochrome P450
Gene Summary 'Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]'
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).

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