GCKR (NM_001486) Human Untagged Clone

CAT#: SC119244

GCKR (untagged)-Human glucokinase (hexokinase 4) regulator (GCKR)


  "NM_001486" in other vectors (6)

Reconstitution Protocol

USD 760.00

In Stock*

Size
    • 10 ug

Product Images

Other products for "GCKR"

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol GCKR
Synonyms FGQTL5; GKRP
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC119244 sequence for NM_001486 edited (data generated by NextGen Sequencing)
ATGCCAGGCACAAAACGGTTTCAACATGTCATTGAGACCCCGGAGCCTGGCAAGTGGGAG
TTGTCTGGGTACGAGGCAGCTGTGCCAATCACGGAGAAGTCAAACCCACTGACCCAGGAT
CTAGACAAAGCAGATGCTGAGAACATTGTTCGACTGCTAGGGCAATGTGATGCTGAGATC
TTCCAGGAGGAGGGGCAAGCCCTGTCCACATACCAGAGACTCTACAGCGGATCCATTCTG
ACCACCATGGTACAGGTGGCTGGGAAAGTTCAGGAAGTGCTGAAGGAGCCAGATGGGGGG
CTGGTTGTGCTGAGTGGAGGGGGCACCTCTGGCCGGATGGCATTCCTCATGTCGGTGTCC
TTTAATCAGCTGATGAAAGGTCTGGGACAGAAACCTCTTTACACCTACCTCATTGCAGGT
GGTGACAGGTCTGTGGTGGCCTCTAGGGAGGGGACAGAAGATAGTGCCTTGCACGGGATT
GAGGAACTGAAGAAGGTGGCTGCCGGGAAGAAGAGAGTGATTGTCATTGGCATTTCTGTG
GGACTCTCTGCTCCCTTTGTGGCAGGCCAGATGGACTGCTGCATGAACAACACAGCTGTC
TTCTTGCCAGTCCTGGTTGGCTTCAATCCAGTGAGCATGGCCAGAAATGACCCCATTGAA
GACTGGAGTTCAACATTCCGACAAGTAGCAGAGCGGATGCAGAAAATGCAGGAGAAACAG
AAAGCTTTTGTGCTCAATCCTGCCATCGGGCCCGAGGGTCTCAGCGGCTCCTCCCGGATG
AAAGGTGGAAGTGCCACCAAGATTCTGCTGGAAACCCTGTTATTAGCAGCCCATAAGACT
GTGGACCAGGGCATTGCAGCATCTCAAAGATGCCTCCTGGAAATCTTGCGGACATTTGAG
CGAGCTCATCAGGTGACCTACAGCCAAAGCCCCAAGATTGCCACCCTGATGAAGAGTGTC
AGCACCAGTCTGGAGAAGAAAGGCCACGTGTACCTGGTTGGCTGGCAGACCCTGGGCATC
ATTGCCATCATGGATGGAGTAGAGTGCATCCACACCTTTGGTGCTGATTTCCGAGATGTC
CGTGGCTTTCTCATTGGTGATCACAGTGACATGTTTAACCAGAAGGCTGAGCTCACCAAC
CAGGGTCCCCAGTTCACCTTCTCCCAGGAGGACTTCCTGACTTCCATCCTTCCCTCTCTC
ACGGAAATCGATACTGTGGTCTTCATTTTCACCCTGGATGACAACCTCACGGAGGTGCAG
ACTATAGTGGAGCAGGTGAAAGAGAAGACCAACCACATCCAGGCCCTGGCACACAGCACC
GTGGGTCAGACCTTGCCGATCCCTCTGAAGAAGCTCTTTCCCTCCATCATCAGCATCACA
TGGCCACTGCTTTTCTTTGAATATGAAGGGAACTTCATCCAGAAGTTCCAGCGTGAGCTA
AGCACCAAATGGGTGCTGAATACAGTGAGTACAGGTGCTCATGTGCTTCTTGGTAAGATC
CTACAAAACCACATGTTGGACCTTCGGATTAGCAACTCCAAGCTCTTCTGGCGGGCGCTG
GCCATGCTGCAGCGGTTCTCTGGACAGTCCAAGGCTCGATGCATCGAGAGCCTCCTCCGA
GCGATCCACTTTCCCCAGCCACTGTCAGATGATATTCGGGCTGCTCCCATCTCCTGCCAT
GTCCAGGTTGCACATGAGAAGGAACAGGTGATACCCATCGCCTTGCTGAGCCTCCTATTC
CGGTGCTCGATCACTGAGGCTCAGGCACACCTGGCTGCAGCTCCTTCTGTCTGTGAGGCT
GTCAGGAGTGCTCTTGCTGGGCCAGGTCAGAAGCGCACTGCGGACCCCCTCGAGATCCTA
GAGCCTGACGTTCAGTGA

Clone variation with respect to NM_001486.3
230 a=>g;1337 t=>c
>OriGene 5' read for NM_001486 unedited
GTTAGCATTTGTATACTATCACTATAGGCGGCACGCGATTCGGCACGATCTGAAGAGCAG
GAGGAACAGTGTATCCACAGCGTGGGACCATGCCAGGCACAAAACGGTTTCAACATGTCA
TTGAGACCCCGGAGCCTGGCAAGTGGGAGTTGTCTGGGTACGATGCAGCTGTGCCAATCA
CGGAGAAGTCAAACCCACTGACCCATGATCTATACAAAGCAGATGCTGATAACATTGTTC
GACTGCTAAGGCAATGTGATGCTGAGATCTTCCAGGAGGAGGGGCAAGCCCTGTCCACAT
ACCATAGACTCTACAGCGGATCCATTCTGACCACCATGGTACAGGTGGCTGGGAAAGTTC
ATGAAGTGCTGAAGGATCCAGATGGGGGGCTGGTTGTGCTGATTGGAGGGGGCACCTCTG
GCCGGATGGCATTCCTCATGTCGGTGTCCTTTAATCAGCTGATGAAAGGTCTGGGACAGA
AACCTCTTTACACCTACCTCATTGCAGGTGGTGACAGGTCTGTGGTGGCCTCTATGGAGG
GGACAGAAGATAGTGCCTTGCACGGGATTGAAGAACTGAAGAATGTGGCTGCCGGGAAGA
ATATAGTGATTGTCATTGGCATTTCTGTGGGACTCTCTGCTCCCTTTGTGGCAGGCCAGA
TGGACTGCTGCATGAACAACACAGCTGTCTTCTTGCCAGTCCTGGTTGGCTTCAATCCAG
TGAGCATGGCCAGAAATGACCCCATTGTAGACTGGAGTTCAACATTCCGACAAGTAGCAT
AGCGGATGCAGAAAATGCAAGATAAACAGAAAGCTTTTGTGCTCAATCCTGCCATCAGGC
CCCGATGGTCTCATCGGCTCCTNCCCGATGATATGTGGGAGTGCCCACAAGATTCTGCTG
GAAAACCTGTTATTATCAGCCATTAGACTGTGCAC
>OriGene 3' read for NM_001486 unedited
GTTGACCATTGGCTGATGGCAACTTGCCAGGNCCAGTATAGGCCTGGGGNAGGGTCACAG
GGCATGCCACCCGGGTATCTGTTCAGGCAAACAGCTATGACCGCGGCCGCAATCTAGAGT
CGAGTTTTTTTTTTTTTTTTTTTTTTTTAACTTTCCAAAATAAGACATTTCATTTTATTT
CTGAAATCAGAATAAGTCGGTGAGAGTAGAAACCACTAGGTCGAGAGCAAGAACTCTCCC
CCAAAGTGGAGAGAATATTTCTCCCTACCCTGGGCTGCGGATGCCCTGGAAACGGGGCTT
CTTCCTCCCACATGTTCTGCTGGCACAAGTCCCCTTGGGCGGGCTGGGCTGAAGTGGGCA
GGGTTGGGCCCCTTTCACCCACCCAGAAACATGGGTTCACTGAACGTCAGGCTCTAGGAT
CTCGAGGGGGTCCGCAGTGCGCTTCTGACCTGGCCCAGCAAGAGCACTCCTGACAGCCTC
ACAGACAGAAGGAGCTGCAGCCAGGTGTGCCTGAGCCTCAGTGATCGAGCACCGGAATAG
GAGGCTCAGCAAGGCGATGGGTATCACCTGTTCCTTCTCATGTGCAACCTGGACATGGCA
GGAGATGGGAGCAGCCCGAATATCATCTGACAGTGGCTGGGGAAAGTGGATCGCTCGGAG
GAGGCTCTCGATGCATCGAGCCTTGGACTGTCCAGAGAACCGCTGCAGCATGGCCAGCGC
CCGCCAGAAGAGCTTGGAGTTGCTAATCCGAAGTCCAACATGTGGTTGTGTAGGATCTTA
CCAAGAAGCACATGAGCACCTGTACTCACTGTATTCAGCACCCTTTTTGTGCTTAGCTCA
CGCTGGAACTTCTGGATGAAGTTCCCTTCATATTCAAGAAAAACAGTGGCCATGTGATGC
TGAT
Restriction Sites NotI-NotI     
ACCN NM_001486
Insert Size 2250 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_001486.2, NP_001477.1
RefSeq Size 2197 bp
RefSeq ORF 1878 bp
Locus ID 2646
Cytogenetics 2p23.3
Domains SIS
Gene Summary 'This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY). [provided by RefSeq, Jul 2008]'

Other Versions

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.