CDS1 (NM_001263) Human Untagged Clone

CAT#: SC119345

CDS1 (untagged)-Human CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 (CDS1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CDS1
• Synonyms: CDS 1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC119345 sequence for NM_001263 edited (data generated by NextGen Sequencing)
  ATGTTGGAGCTGAGGCACCGGGGAAGCTGCCCCGGCCCCAGGGAAGCGGTGTCGCCGCCA
  CACCGCGAGGGAGAGGCGGCCGGCGGCGACCACGAAACCGAGAGCACCAGCGACAAAGAA
  ACAGATATTGATGACAGATATGGAGATTTGGATTCCAGAACAGATTCTGATATTCCGGAA
  ATTCCACCATCCTCAGATAGAACCCCTGAGATTCTCAAAAAAGCTCTATCTGGTTTATCT
  TCAAGGTGGAAAAACTGGTGGATACGTGGAATTCTCACTCTAACTATGATCTCGTTGTTT
  TTCCTGATCATCTATATGGGATCCTTCATGCTGATGCTTCTTGTTCTGGGCATCCAAGTG
  AAATGCTTCCATGAAATTATCACTATAGGTTATAGAGTCTATCATTCTTATGATCTACCA
  TGGTTTAGAACACTAAGTTGGTACTTTCTATTGTGTGTAAACTACTTTTTCTATGGAGAG
  ACTGTAGCTGATTATTTTGCTACATTTGTTCAAAGAGAAGAACAACTTCAGTTCCTCATT
  CGCTACCATAGATTTATATCATTTGCCCTCTATCTGGCAGGTTTCTGCATGTTTGTACTG
  AGTTTGGTGAAGAAACATTATCGTCTGCAGTTTTATATGTTCGCATGGACTCATGTCACT
  TTACTGATAACTGTCACTCAGTCACACCTTGTCATCCAAAATCTGTTTGAAGGCATGATA
  TGGTTCCTTGTTCCAATATCAAGTGTTATCTGCAATGACATAACTGCTTACCTTTTTGGA
  TTTTTTTTTGGGAGAACTCCATTAATTAAGTTGTCTCCTAAAAAGACTTGGGAAGGATTC
  ATTGGTGGTTTCTTTTCCACAGTTGTGTTTGGATTCATTGCTGCCTATGTGTTATCCAAA
  TACCAGTACTTTGTCTGCCCAGTGGAATACCGAAGTGATGTAAACTCCTTCGTGACAGAA
  TGTGAGCCCTCAGAACTTTTCCAGCTTCAGACTTACTCACTTCCACCCTTTCTAAAGGCA
  GTCTTGAGACAGGAAAGAGTGAGCTTGTACCCTTTCCAGATCCACAGCATTGCACTGTCA
  ACCTTTGCATCTTTAATTGGCCCATTTGGAGGCTTCTTTGCTAGTGGATTCAAAAGAGCC
  TTCAAAATCAAGGATTTTGCAAATACCATTCCTGGACATGGTGGGATAATGGACAGATTT
  GATTGTCAGTATTTGATGGCAACTTTTGTACATGTGTACATCACAAGTTTTATAAGGGGC
  CCAAATCCCAGCAAAGTGCTACAGCAGTTGTTGGTGCTTCAACCTGAACAGCAGTTAAAT
  ATATATAAAACCCTGAAGACTCATCTCATTGAGAAAGGAATCCTACAACCCACCTTGAAG
  GTATAA
  
  Clone variation with respect to NM_001263.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001263 unedited
  NTTGTTCAAATTTTGNTATACGACTCACTATAGGGCGGCCGCGNAATTCGCACGAGGGGC
  AACCGGAGGCCGCGTCTCCGCCTTCTCTGCTCGCGCCTGGCGCCCGGAGCCTGCCCGGGA
  CCTCCGCCGGAGCCGCGCTCGCTGCAGGCGGCCTCGAGCGCTCTCTCGTTGATGCCGTTT
  TGGAGGTGACCGGCGCGGCGGCCGCTCTATGGTGGGGCCGCGTTAGTGGCTGCGGCTCCG
  CGGGACTCCAGGGCGCGGCTGCGAGGTGGCGGGGCGCCCCGCCTGCAGAACCCTGCTTGC
  AGCTCAGGTTTCGGGGTGCTTGAGGAGGCCGCCACGGCAGCGCGGGAGCGGAAGATGTTG
  GAGCTGAGGCACCGGGGAAGCTGCCCCGGCCCCAGGGAAGCGGTGTCGCCGCCACACCGC
  GAGGGAGAGGCGGCCGGCGGCGACCACGAAACCGAGAGCACCAGCGACCAAGACACCAGA
  TATTGATGACAGATATGGAGATTTGGATTCCAGAACAGATTCTGATATTCCGGAAATTCC
  ACCATCCTCACATAGAACCCCTGAGATTCTCAAAAAAGCTCTATCTGGTTTATCCTCCAA
  GCGGATAAACTGCCGGATACGTGGAATTCTCACTCCTAACTATGATCTCGCTGTTTTTCC
  TGAACATCTATATGGGGATCCTTCATGCTGATGCTTCTTGGTCTGGGCTCCCAGTGAAAT
  GCTTCCCTGAAATATCCCCATAGGTTATAGAGTCTATCATTCCTATGAACCACCATGGTC
  TAGAACACTTAATTGGTACCTTTCATTCGGTGTAAACCACCTTTTCTATGGAAAGACTGA
  ACCTGACTATTTGCCACCTTTGCTCAAAGAGAAGACCACCTTAGTTCCTCTTCCCTACCA
  T
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001263 unedited
  CGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTAAATCCAACTAAGCCCTTTA
  GAAAGTACTCCAGACTACATGAGGAGGAAGTGCAGGAGAACTGACTTCCTATTGTGCCTT
  GCATAAAACATTTTGCTAAAATTAAAAGCAGCTCCAAGTGCAAAAGTAAATATTTGTGCA
  AAAAGGCACACTGCCAGGTGCAATCTTAAAACATCGTCAACTTACTCATTTTATAGTGTT
  TGACTCTTTTCAATACCAGTCTTTTAAATTATGAAACCTAGCAAGTAAGGGGAAGGAAGT
  TCACATCAGAAAATACACTTTAGAAAAGGTACAAGACATTTTGCTGGCAATTTGCTACTT
  ATTTCATAACATAGATCAAGTAAGTGTTTGTTAAATATTCACAGTAATTTCAGAGAGAAA
  CATATCTCCAAAACTTCAACCTATTGCATTTTTAACTATTTTTCTGTACAATTTATAAAA
  CATCTGTCAGTGTTTTTCTGAATAATTCCTTCTTGTCAGTCCTTCCCTCTCTGGATCCAG
  TTATACCTTCAAGGTGGGTTGTAGGATTCCTTTCTCAATGAGATGAGTCTTCAGGGTTTT
  ATATATATTTAACTGCTGTTCAGGTTGAAGCACCAACAACTGCTGTAGCACTTTGCTGGG
  ATTTGGGCCCCTTATAAAACTTGTGATGTACACATGTACAAAAGTTGCCATCAAATACTG
  ACAATCAAATCTGTCCATTATCCCACCATGTCCAGAAATGGTATTTGCAAAATCCTTGAT
  TTTGAAGGCTCTTTTGATCCACTAGNCAAGAGCCTNCAATGGGCCAATTAAGATGCAAAG
  GTGACATGCATGCTGTGATCTGGAAGGGTACAGCTACTCTTTCTGTCTAGACTGCCTTAA
  AAGGGTGGAGGAGTAATCTGAGCTGGAAAGTTGAGGCTCCATCTGCCCAAGAGTACATAC
  TCGGATCCCTGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_001263
• Insert Size: 2150 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001263.2, NP_001254.2
• RefSeq Size: 2374 bp
• RefSeq ORF: 1386 bp
• Locus ID: 1040
• Cytogenetics: 4q21.23
• Domains: CTP_transf_1
• Protein Families: Transmembrane
• Protein Pathways: Glycerophospholipid metabolism, Metabolic pathways, Phosphatidylinositol signaling system
• Gene Summary: 'Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. This gene encodes an enzyme which regulates the amount of phosphatidylinositol available for signaling by catalyzing the conversion of phosphatidic acid to CDP-diacylglycerol. This enzyme is an integral membrane protein localized to two subcellular domains, the matrix side of the inner mitochondrial membrane where it is thought to be involved in the synthesis of phosphatidylglycerol and cardiolipin and the cytoplasmic side of the endoplasmic reticulum where it functions in phosphatidylinositol biosynthesis. Two genes encoding this enzyme have been identified in humans, one mapping to human chromosome 4q21 and a second to 20p13. [provided by RefSeq, Jul 2008]'