Caveolin 2 (CAV2) (NM_001233) Human Untagged Clone

CAT#: SC119366

CAV2 (untagged)-Human caveolin 2 (CAV2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CAV2
• Synonyms: CAV
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001233, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGGGCTGGAGACGGAGAAGGCGGACGTACAGCTCTTCATGGACGACGACTCCTACAGCCACCACAGCG
  GCCTCGAGTACGCCGACCCCGAGAAGTTCGCGGACTCGGACCAGGACCGGGATCCCCACCGGCTCAACTC
  GCATCTCAAGCTGGGCTTCGAGGATGTGATCGCAGAGCCGGTGACTACGCACTCCTTTGACAAAGTGTGG
  ATCTGCAGCCATGCCCTCTTTGAAATCAGCAAATACGTAATGTACAAGTTCCTGACGGTGTTCCTGGCCA
  TTCCCCTGGCCTTCATTGCGGGAATTCTCTTTGCCACCCTCAGCTGTCTGCACATCTGGATTTTAATGCC
  TTTTGTAAAGACCTGCCTAATGGTTCTGCCTTCAGTGCAGACAATATGGAAGAGTGTGACAGATGTTATC
  ATTGCTCCATTGTGTACGAGCGTAGGACGATGCTTCTCTTCTGTCAGCCTGCAACTGAGCCAGGATTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001233 unedited
  NCCCGTTCAAATATTTGTATACGACTCACTTNGGGCGGCCGCGNAATTCGCACGAGGGCG
  AGGGGGGGCGGGGCCGGGCGCTACGGGAAGGGGAGGCCGCGCGGACCGGGAGCCGCACCG
  CGCCAGCCGGGCTGCAGCGGCCGCGCACCAAGGCTGCGATGGGGCTGGAGACGGAGAAGG
  CGGACGTACAGCTCTTCATGGACGACGACTCCTACAGCCACCACAGCGGCCTCGAGTACG
  CCGACCCCGAGAAGTTCGCGGACTCGGACCAGGACCGGGATCCCCACCGGCTCAACTCGC
  ATCTCAAGCTGGGCTTCGAGGATGTGATCGCAGAGCCGGTGACTACGCACTCCTTTGACA
  AAGTGTGGATCTGCAGCCATGCCCTCTTTGAAATCAGCAAATACGTAATGTACAAGTTCC
  TGACGGTGTTCCTGGCCATTCCCCTGGCCTTCATTGCGGGAATTCTCTTTGCCACCCTCA
  GCTGTCTGCACATCTGGATTTTAATGCCTTTTGTAAAGACCTGCCTAATGGTTCTGCCTT
  CAGTGCAGACATATTGGAAGAGTGTGACAGATGTTATCATTGCTCCATTGTGTACGAGCG
  TAGGACGATGCTTCTCTTCTGTCAGCCTGCAACTGACCCAGGATTGAATACTTGGACCCC
  ANGTCTGGGAGATTGGGATACTGTNAATACTTCTTTGTTATTATAACATAAAAGCACCAC
  TGGTTCTGTTCATTTCCCTAGCTGTTCTAATTAAGAAACCTATTAAGATGAGCAACCACA
  TTTAGGAATGGTTTATTGACCAGGTCTTTTCAAATAATGGCTTTTCTAATTAATAGCCCA
  AAGATTTCATATCTTNACTTTGTTACCCGATTATCCCGNTAAGTTGACCCACTTAGATTT
  AAGGCGGAACAGTTTTGCTTAGTACAATAGTATACT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001233 unedited
  ACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTCTTTTTTTTTTTGAGAC
  AGACTCTTGCTCTGTTGCCAGGCGGGAGTGCAGTGGCATGATTTTGGCTCACTGCAACCT
  CTGCCTCCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCAGGTAGCTGGGACTACAGG
  TGCATGCCACCATGCCCAACTAATTTTTTTGTATTTTTAGTAGAGACGGGGTATCACCAT
  GTTGGCCAGGATGGTCTTGATCTCCTGACCTCATGATCCACCCGCCTTGGCCTCCCAAAG
  TGCTGGGATTACAGGGGTGAGCCACCATGCCCGGCCCAGAAATAATGAGATTTTTCAAAG
  CAACAGTGATTCATCACACTGAAATAGGACTCTACAGTTCAAAATGACAAGAATAACTTT
  ATCCTGTGTTACATACCAATATTAGAGAAATCTTAAAAGTTTGTAGCTGTTAGTTTTTAG
  TTTATGCATGTAGTTCAGTAGCCCAAGTTGACAACTCCCCTGTCTCTCTACATGAATCAC
  TGTAGTTGAAATTGTACTAAAGTATCAGAAGTAACATTTACTGTAAAATGTTAAATAGCA
  CCAATATTACTTGAAAGTAAAGTGAGACATTAATAGGAATGCTGACACAGATTTAATTNC
  TAACTACTAGAGAGAAAGCATCTCCTAGACAAAATACTATTTAGATATGAATTATTTCAG
  GATCACAGCCAGAAAAAGTCATAAAACATTTTAGATTTTGCTTTGAAAAGTTAGAAAAAG
  AAGCTTTGNGTATCGCTCTTTTATCCTTTATTTCCCAGNAAAATGTACAAATGCTTNACT
  TATTCAGAACAGTGCAATCTTACCAATGAAATTTACCTTGGGGGGAGCCACATTTACTTA
  TTCCATAAATAAGTTCACCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_001233
• Insert Size: 2140 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001233.3, NP_001224.1
• RefSeq Size: 3332 bp
• RefSeq ORF: 489 bp
• Locus ID: 858
• Cytogenetics: 7q31.2
• Domains: Caveolin
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Focal adhesion
• Gene Summary: 'The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. This gene and related family member (CAV1) are located next to each other on chromosome 7, and express colocalizing proteins that form a stable hetero-oligomeric complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Additional isoforms resulting from the use of alternate in-frame translation initiation codons have also been described, and shown to have preferential localization in the cell (PMID:11238462). [provided by RefSeq, May 2011]'
  Transcript Variant: This variant (1) encodes two isoforms resulting from the use of alternate in-frame, translation initiation codons. This RefSeq represents the longer isoform (a, also known as alpha) derived from the use of the upstream AUG (at nt 182-184). Isoform alpha has been shown to localize mostly in the golgi (PMID:11238462).