Carbonic Anhydrase XI (CA11) (NM_001217) Human Untagged Clone

CAT#: SC119398

CA11 (untagged)-Human carbonic anhydrase XI (CA11)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CA11
• Synonyms: CA-RP; CA-RP II; CA-XI; CARP-2; CARPX1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001217, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGGGGCTGCAGCTCGTCTGAGCGCCCCTCGAGCGCTGGTACTCTGGGCTGCACTGGGGGCAGCAGCTC
  ACATCGGACCAGCACCTGACCCCGAGGACTGGTGGAGCTACAAGGATAATCTCCAGGGAAACTTCGTGCC
  AGGGCCTCCTTTCTGGGGCCTGGTGAATGCAGCGTGGAGTCTGTGTGCTGTGGGGAAGCGGCAGAGCCCC
  GTGGATGTGGAGCTGAAGAGGGTTCTTTATGACCCCTTTCTGCCCCCATTAAGGCTCAGCACTGGAGGAG
  AGAAGCTCCGGGGAACCTTGTACAACACCGGCCGACATGTCTCCTTCCTGCCTGCACCCCGACCTGTGGT
  CAATGTGTCTGGAGGTCCCCTCCTTTACAGCCACCGACTCAGTGAACTGCGGCTGCTGTTTGGAGCTCGC
  GACGGAGCCGGCTCGGAACATCAGATCAACCACCAGGGCTTCTCTGCTGAGGTGCAGCTCATTCACTTCA
  ACCAGGAACTCTACGGGAATTTCAGCGCTGCCTCCCGCGGCCCCAATGGCCTGGCCATTCTCAGCCTCTT
  TGTCAACGTTGCCAGTACCTCTAACCCATTCCTCAGTCGCCTCCTTAACCGCGACACCATCACTCGCATC
  TCCTACAAGAATGATGCCTACTTTCTTCAAGACCTGAGCCTGGAGCTCCTGTTCCCTGAATCCTTCGGCT
  TCATCACCTATCAGGGCTCTCTCAGCACCCCGCCCTGCTCCGAGACTGTCACCTGGATCCTCATTGACCG
  GGCCCTCAATATCACCTCCCTTCAGATGCACTCCCTGAGACTCCTGAGCCAGAATCCTCCATCTCAGATC
  TTCCAGAGCCTCAGCGGTAACAGCCGGCCCCTGCAGCCCTTGGCCCACAGGGCACTGAGGGGCAACAGGG
  ACCCCCGGCACCCCGAGAGGCGCTGCCGAGGCCCCAACTACCGCCTGCATGTGGATGGTGTCCCCCATGG
  TCGCTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001217 unedited
  TATAACACCCGCCCGTTGNCGCAATGGGCGGTAGGCGTGTACGGTGGNGAGTCTATATAA
  GCAGAGCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGC
  GAATTCGGCACGAGGCCTCGTGCCGAATTCGGCACGAGGGGAAGATCAGGAGCTAGAGGG
  AGACTGGAGGGTTCCGGGAAAAGAGCAGAGGAAAGAGGAAAGACACAGAGAGACGGGAGA
  GAGAAGAAGAGTGGGTTTGAAGGGCGGATCTCAGTCCCTGGCTGCTTTGGCATTTGGGGA
  ACTGGGACTCCCTGTGGGGAGGAGAGGAAAGCTGGAAGTCCTGGAGGGACAGGGTCCCAG
  AAGGAGGGGACAGAGGAGCTGAGAGAGGGGGGCAGGGCGTTGGGCAGGGGTCCCTCGGAG
  GCCTCCTGGGGATGGGGGGCTGCAGCTCGTCTGAGCGCCCCTCGAGCGCTGGTACTCTGG
  GCTGCACTGGGGGCAGCAGCTCACATCGGACCAGCACCTGACCCCGAGGACTGGGTGGAG
  CTACAAGGATAATCTCCAGGGAAACTTCGTGCCAGGGCCNTCCTTTCTGGGGCCTGGTGA
  ATGCAGCGTGGAGTTCTGTGTGCTGTGGGGAAAGCGCAGAGCCCCGTGGATGTGGAGCTA
  AAAAAGGTTCTTTATGGACCCCTTTCTGCCCCATTTAGGCTCAGCACTGGGAGAGAGAAG
  CTNCGGGGGAACCTTTGTACACACCGGCCGACATGTCTNCTTCCTGCCTGCACCCCGACC
  TGTGGTCATGTGTCTGGGGGAGGTCCCCTTCTTTACAGCCCCCGACTCATTGAACTGCGG
  GTGCTTGTTTGGAGCTCCCGAACGGACCCGGCTCGGGACATCAAATTCACCACCAGGGCT
  CTTTGTTTGAGGGCAGCTCAT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001217 unedited
  GCACTTCCAGCCAGAAGCCTGGGAGGGTCACAGGATGCCACCCGGATCTGTTCAGAAACG
  CTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTAGTATTCTGTCC
  CTTTAATAGCTTTGTTTTAGGGGTAACTCCCCTCGCCTTGTGGGGAGGCTTAAGACGGGC
  GGGTGCAATCCTCGAAGGGGAGTCTCAGCGACCATGGGGGACACCATCCACATGCAGGCG
  GTAGTTGGGGCCTCGGCAGCGCCTCTCGGGGTGCCGGGGGTCCCTGTTGCCCCTCAGTGC
  CCTGTGGGCCAAGGGCTGCAGGGGCCGGCTGTTACCGCTGAGGCTCTGGAAGATCTGAGA
  TGGAGGATTCTGGCTCAGGAGTCTCAGGGAGTGCATCTGAAGNNAGGTGATATTGAGGGC
  CCGGTCAATGAGGATCCAGGTGACAGTCTCGGAGCAGGGCGGGGTGCTGAGAGAGCCCTG
  ATAGGTGATGAAGCCGAAGGATTCAGGGAACAGGAGCTCCAGGCTCANGTCTTGAAGAAA
  GTAGGCATCATTCTTGTAGGAGATGCGAGTGATGGTGTCGCGGTTAAAGAGGCGACTGAG
  GAATGGGTTANAGGTACTGGCAACGTTGACAAGAGGCTGAGAATGGCCAGGCCATTGGGG
  CCCGCGGAGGCAGCGCTGAAATTCCGTAAAGTTCCTGTTTGAAGTGAATGAGCTGCCTNN
  NNCATAAAACCCCTGTGGTTGATCTGATGTTCCGAGCCGGCTTCGTCGCGAGCTCCAACA
  GCANNCGCANTCACTGANTCGGTGGCTGTAAAGAAGGGACCTTCGACCCATGACCCCAGT
  NCGGGTGCAGCAGAAGGAAACATGTCGCCCGTGTGTTCAAAGGTCCCGGAGCTCTCTTCT
  CCGGGNTGAACTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_001217
• Insert Size: 1700 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001217.3, NP_001208.2
• RefSeq Size: 1686 bp
• RefSeq ORF: 987 bp
• Locus ID: 770
• Cytogenetics: 19q13.33
• Domains: carb_anhydrase
• Protein Families: Druggable Genome, Secreted Protein
• Gene Summary: ' Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XI is likely a secreted protein, however, radical changes at active site residues completely conserved in CA isozymes with catalytic activity, make it unlikely that it has carbonic anhydrase activity. It shares properties in common with two other acatalytic CA isoforms, CA VIII and CA X. CA XI is most abundantly expressed in brain, and may play a general role in the central nervous system. [provided by RefSeq, Jul 2008]'