ADK (NM_001123) Human Untagged Clone

CAT#: SC119409

ADK (untagged)-Human adenosine kinase (ADK), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ADK
• Synonyms: AK
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001123, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGACGTCAGTCAGAGAAAATATTCTCTTTGGAATGGGAAATCCTCTGCTTGACATCTCTGCTGTAGTGG
  ACAAAGATTTCCTTGATAAGTATTCTCTGAAACCAAATGACCAAATCTTGGCTGAAGACAAACACAAGGA
  ACTGTTTGATGAACTTGTGAAAAAATTCAAAGTCGAATATCATGCTGGTGGCTCTACCCAGAATTCAATT
  AAAGTGGCTCAGTGGATGATTCAACAGCCACACAAAGCAGCAACATTTTTTGGATGCATTGGGATAGATA
  AATTTGGGGAGATCCTGAAGAGAAAAGCTGCTGAAGCCCATGTGGATGCTCATTACTACGAGCAGAATGA
  GCAGCCAACAGGAACTTGTGCTGCATGCATCACTGGTGACAACAGGTCCCTCATAGCTAATCTTGCTGCT
  GCCAATTGTTATAAAAAGGAAAAACATCTTGATCTGGAGAAAAACTGGATGTTGGTAGAAAAAGCAAGAG
  TTTGTTATATAGCAGGCTTTTTTCTTACAGTTTCCCCAGAGTCAGTATTAAAGGTGGCTCACCATGCTTC
  TGAAAACAACAGGATTTTCACTTTGAATCTATCTGCACCGTTTATTAGCCAGTTCTACAAGGAATCATTG
  ATGAAAGTTATGCCTTATGTTGATATACTTTTTGGAAATGAGACAGAAGCTGCCACTTTTGCTAGAGAGC
  AAGGCTTTGAGACTAAAGACATTAAAGAGATAGCCAAAAAGACACAAGCCCTGCCAAAGATGAACTCAAA
  GAGGCAGCGAATCGTGATCTTCACCCAAGGGAGAGATGACACTATAATGGCTACAGAAAGTGAAGTCACT
  GCTTTTGCTGTCTTGGATCAAGACCAGAAAGAAATTATTGATACCAATGGAGCTGGAGATGCATTTGTTG
  GAGGTTTTCTGTCTCAACTGGTCTCTGACAAGCCTCTGACTGAATGTATCCGTGCTGGCCACTATGCAGC
  AAGCATCATAATTAGACGGACTGGCTGCACCTTTCCTGAGAAGCCAGACTTCCACTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001123 unedited
  NGGGTTGTCAGATTTTGTATACGACTCCTATAGGGCGGCCGCGAATTCGCACCAGCCCAG
  TCGCTGAGTGCCTGAGCCGGGAAGCAGTTGCTGTGGTACCTGCTGCTGCCCGAGCGGACG
  TAGAGCATCGGACGCGGGCGCCGTGGCGTTGGGCAGGAGGGCGAAGCCATGACGTCAGTC
  AGAGAAATATTCTCTTTGGAATGGGAAATCCTCTGCTTGACATCTCTGCTGTAGTGGACA
  AAGATTTCCTTGATAAGTATTCTCTGAAACCAAATGACCAAATCTTGGCTGAAGACAAAC
  ACAAGGAACTGTTTGATGAACTTGTGAAAAAATTCAAAGTCGAATATCATGCTGGTGGCT
  CTACCCAGAATTCAATTAAAGTGGCTCAGTGGATGATTCAACAGCCACACAAAGCAGCAA
  CATTTTTTGGATGCATTGGGATAGATAAATTTGGGGAGATCCTGAAGAGAAAAGCTGCTG
  AAGCCCATGTGGATGCTCATTACTACGAGCAGAATGAGCAGCCAACAGGAACTTGTGCTG
  CATGCATCACTGGTGACAACAGGTCCCTCATAGCTAATCTTGCTGCTGCCAATTGTTATA
  AAAAGGAAAAACATCTTGATCTGGAGAAAAACTGGATGTTGGTAGAAAAAGCAAGAGTTT
  GTTATATAGCAGGCTTTTTTCTTACAGTTTCCCCAGAGTCAGTATTAAAGGTGGCTCACC
  ATGCTTCTGAAACAACAGGATTNTCACTTTGAATCTATCTGCACCGTTTATTAGCCAGTT
  CTACAGGAATCATTGATGAAAGTTATGCCTTATGGTGATATACTNTNTGGAAATGAGACA
  GAAGCTGNCACTTTTGCTAGAGAGCAAGGCTTNTGAGACTAAGACATTTAAGAGATAGCC
  CAAAAGAACCA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_001123
• ORF Size: 1038 bp
• Insert Size: 2100
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_001123.2, NP_001114.2
• RefSeq Size: 2082
• RefSeq ORF: 1038
• Locus ID: 132
• Domains: pfkB
• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Purine metabolism
• Gene Summary: This gene an enzyme which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
  Transcript Variant: This variant (1), alternately referred to as ADK-short, represents the longest transcript and encodes isoform a.