Adrenomedullin (ADM) (NM_001124) Human Untagged Clone

CAT#: SC119410

ADM (untagged)-Human adrenomedullin (ADM)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ADM
• Synonyms: AM; PAMP
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_001124 edited
  ATGAAGCTGGTTTCCGTCGCCCTGATGTACCTGGGTTCGCTCGCCTTCCTAGGCGCTGAC
  ACCGCTCGGTTGGATGTCGCGTCGGAGTTTCGAAAGAAGTGGAATAAGTGGGCTCTGAGT
  CGTGGGAAGAGGGAACTGCGGATGTCCAGCAGCTACCCCACCGGGCTCGCTGACGTGAAG
  GCCGGGCCTGCCCAGACCCTTATTCGGCCCCAGGACATGAAGGGTGCCTCTCGAAGCCCC
  GAAGACAGCAGTCCGGATGCCGCCCGCATCCGAGTCAAGCGCTACCGCCAGAGCATGAAC
  AACTTCCAGGGCCTCCGGAGCTTTGGCTGCCGCTTCGGGACGTGCACGGTGCAGAAGCTG
  GCACACCAGATCTACCAGTTCACAGATAAGGACAAGGACAACGTCGCCCCCAGGAGCAAG
  ATCAGCCCCCAGGGCTACGGCCGCCGGCGCCGGCGCTCCCTGCCCGAGGCCGGCCCGGGT
  CGGACTCTGGTGTCTTCTAAGCCACAAGCACACGGGGCTCCAGCCCCCCCGAGTGGAAGT
  GCTCCCCACTTTCTTTAG
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001124 unedited
  NGTTCAAATTTGTATACGACTCACTATAGGCGGCCGCGATTCGGCACGAGGAGACTTTCT
  CCTTCAGTACTTGGCAGATCACTCTCTTAGCAGGGTCTGCGCTTCGCAGCCGGGATGAAG
  CTGGTTTCCGTCGCCCTGATGTACCTGGGTTCGCTCGCCTTCCTAGGCGCTGACACCGCT
  CGGTTGGATGTCGCGTCGGAGTTTCGAAAGAAGTGGAATAAGTGGGCTCTGAGTCGTGGG
  AAGAGGGAACTGCGGATGTCCAGCAGCTACCCCACCGGGCTCGCTGACGTGAAGGCCGGG
  CCTGCCCAGACCCTTATTCGGCCCCAGGACATGAAGGGTGCCTCTCGAAGCCCCGAAGAC
  AGCAGTCCGGATGCCGCCCGCATCCGAGTCAAGCGCTACCGCCAGAGCATGAACAACTTC
  CAGGGCCTCCGGAGCTTTGGCTGCCGCTTCGGGACGTGCACGGTGCAGAAGCTGGCACAC
  CAGATCTACCAGTTCACAGATAAGGACAAGGACAACGTCGCCCCCAGGAGCAAGATCAGC
  CCCCAGGGCTACGGCCGCCGGCGCCGGCGCTCCCTGCCCGAGGCCGGCCCGGGTCGGACT
  CTGGTGTCTTCTAAGCCACAAGCACACGGNGCTCCAGCCCCCCCGAGTGGAAGTGCTCCC
  CACTTTCTTTAGGATTTANGCGCCCATGGTACAAGGAATAGTCGCGCAAGCATCCCGCTG
  GTGCCTNCCGGGGACGAAGACTTCCCGAGCGGGTGTGGGACCGGGCTCTGACAGCCCCTG
  CGAGACCCTGAGTCCGGNAGGCACCGTNNCCGCGCGAGCTCTGGCTTTGCAGGGCCCCTN
  CTTCTGNGGGGCTCGCTTCTTACCTTTGCTCAGTGCAGTGCCCCAGGGGGCGNGTGCANA
  AAATCCCGATGNTTGCCAGCTTAAGGAGAGAGAACTGANAT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_001124
• Insert Size: 1650 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001124.1, NP_001115.1
• RefSeq Size: 1449 bp
• RefSeq ORF: 558 bp
• Locus ID: 133
• Cytogenetics: 11p15.4
• Domains: Adrenomedullin
• Protein Families: Druggable Genome, Secreted Protein
• Gene Summary: 'The protein encoded by this gene is a preprohormone which is cleaved to form two biologically active peptides, adrenomedullin and proadrenomedullin N-terminal 20 peptide. Adrenomedullin is a 52 aa peptide with several functions, including vasodilation, regulation of hormone secretion, promotion of angiogenesis, and antimicrobial activity. The antimicrobial activity is antibacterial, as the peptide has been shown to kill E. coli and S. aureus at low concentration. [provided by RefSeq, Aug 2014]'