NUDT2 (NM_001161) Human Untagged Clone

CAT#: SC119427

NUDT2 (untagged)-Human nudix (nucleoside diphosphate linked moiety X)-type motif 2 (NUDT2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NUDT2
• Synonyms: APAH1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC119427 sequence for NM_001161 edited (data generated by NextGen Sequencing)
  ATGGCCTTGAGAGCATGTGGCTTGATCATCTTCCGAAGATGCCTCATTCCCAAAGTGGAC
  AACAATGCAATTGAGTTTTTACTGCTGCAGGCATCAGATGGCATTCATCACTGGACTCCT
  CCCAAAGGCCATGTGGAACCAGGAGAGGATGACTTGGAAACAGCCCTGAGGGAGACCCAA
  GAGGAAGCAGGCATAGAAGCAGGCCAGCTGACCATTATTGAGGGGTTCAAAAGGGAACTC
  AATTATGTGGCCAGGAACAAGCCTAAAACAGTCATTTACTGGCTGGCGGAGGTGAAGGAC
  TATGACGTGGAGATCCGCCTCTCCCATGAGCACCAAGCCTACCGCTGGCTGGGGCTGGAG
  GAGGCCTGCCAGTTGGCTCAGTTCAAGGAGATGAAGGCAGCGCTCCAAGAAGGACACCAG
  TTTCTTTGCTCCATAGAGGCCTGA
  
  Clone variation with respect to NM_001161.4
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001161 unedited
  TGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCTCCTTCTGCTTCGG
  TGCGTTTGCTTCTGAGGATCTCCAGTGTCACAACAAACACATGCCAGCCCTGTTTTACAG
  GGAGCCCTGGAGGAGTTGGGATAGAGGCCACATTGACTGAGGGTAGTTGCCAGGGTCCTG
  CAGTTATACACAAAGTCCTTAGGATAAGACCATGGCCTTGAGAGCATGTGGCTTGATCAT
  CTTCCGAAGATGCCTCATTCCCAAAGTGGACAACAATGCAATTGAGTTTTTACTGCTGCA
  GGCATCAGATGGCATTCATCACTGGACTCCTCCCAAAGGCCATGTGGAACCAGGAGAGGA
  TGACTTGGAAACAGCCCTGAGGGAGACCCAAGAGGAAGCAGGCATAGAAGCAGGCCAGCT
  GACCATTATTGAGGGGTTCAAAAGGGAACTCAATTATGTGGCCAGGAACAAGCCTAAAAC
  AGTCATTTACTGGCTGGCGGAGGTGAAGGACTATGACGTGGAGATCCGCCTCTCCCATGA
  GCACCAAGCCTACCGCTGGCTGGGGCTGGAGGAGGCCTGCCAGTTGGCTCAGTTAAGGAG
  ATGAAGGCAGCGCTCCAAGAAGGACACCAGTTTCTTTGCTCCATAGAGGCCTGAGCTGAC
  TGGAGCAGAGTCATTTGCTTAGCANGATCCTTGTGGGCCTTCTAGATGAAGCCACCCTCA
  GTCAGGGNAAGGTTGTGCTGGTATTTGGCTCATGACAGCCAGAGCAGATTTGTGAAATCN
  GGCTCACTCCAGNTGAGAAGCAGCAAAATCTTGGCTGGNTGGAAAAGGAGGCAAAGAGTA
  AATTTAAAAGGCCAGCCAANNAAGTGAACCTTGTACTTATAAATAAACTCCAGCAGCTCA
  AAAAAAAAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001161 unedited
  CGCAATCTAGTATCGAGTTTTTTTTTTTTTTTTTTGAGCTGCTTGAGGTTTATTTATAAA
  GTACAAGGTACACTTACTGGGCCTGGCCTTTTTAATTTTTACTCTTTTGCCTTCCTTTCC
  ACCCAGCCAAGATTTTTGCTTGCTCTCACCTGGGAGTTGAGCCGATTTCACAAATCTGCT
  CTTGGCTGTCATGAGCCAAATACCAGCACAACCTTCCCTGGACCTGAGGGTGGCTTCATC
  TTATAAGGCCCACAAGGATCCTGCTGAAGCAAATGACTCTGCTCCAGTCAGCTCAGGCCT
  CTATGGAGCAAAGAAACTGGTGTCCTTCTTGGAGCGCTGCCTTCATCTCCTTGAACTGAG
  CCAACTGGCAGGCCTCCTCCAGCCCCAGCCAGCGGTAGGCTTGGTGCTCATGGGAGAGGC
  GGATCTCCACGTCATAGTCCTTCACCTCCGCCAGCCAGTAAATGACTGTTTTAAGCTTGT
  TCCTGGCCACATAATTGAGTTCCCTTTTGAACCCCTCAATAATGGTCAGCTGGCCTGCTT
  CTATGCCTGCTTCCTCTTGGGTCTCCCTCAGGGCTGTTTCCAAGTCATCCTCTCCTGGTT
  CCACATGGCCTTTGGGAGGAGTCCAGTGATGAATGCCATCTGATGCCTGCAGCAGTAAAA
  ACTCAATTGCATTGTTGTCCACTTTGGGAATGATGCATCTTTCGGAGATGATCAAGCCAC
  ATGCTCTCAAGGCCATGTNCTATTCTAAAGACTTTGTGTATAACTGCAAGACCCTGGCAA
  CTACCCTCAGTCAATGTGGGCCTCTATCCCAACTCCTNCAGGGCTCCCTGTAAACAGGGN
  CTGCATGTTGTTNGNTGTGACCCTGGAGACCTCANAAACAAACGCACCGAGCANAAGGAG
  GCCTCTGCCGCATTCCCGGCCGCCCTATAGGAGTCGATTACAAATNCTGACGGTCACTAA
  CGAGCTCTGCTATATGACTCCACCGTACCGCCTACCGCCATTGGTAACGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_001161
• Insert Size: 920 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001161.3, NP_001152.1
• RefSeq Size: 1060 bp
• RefSeq ORF: 444 bp
• Locus ID: 318
• Cytogenetics: 9p13.3
• Domains: NUDIX
• Protein Pathways: Purine metabolism, Pyrimidine metabolism
• Gene Summary: 'This gene encodes a member of the MutT family of nucleotide pyrophosphatases, a subset of the larger NUDIX hydrolase family. The gene product possesses a modification of the MutT sequence motif found in certain nucleotide pyrophosphatases. The enzyme asymmetrically hydrolyzes Ap4A to yield AMP and ATP and is responsible for maintaining the intracellular level of the dinucleotide Ap4A, the function of which has yet to be established. This gene may be a candidate tumor suppressor gene. Alternative splicing has been observed at this locus and four transcript variants, all encoding the same protein, have been identified. [provided by RefSeq, Sep 2011]'
  Transcript Variant: This variant (1) is the full-length transcript. All four variants encode the same protein.