ADCY8 (NM_001115) Human Untagged Clone

CAT#: SC119443

ADCY8 (untagged)-Human adenylate cyclase 8 (brain) (ADCY8)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ADCY8
• Synonyms: AC8; ADCY3; HBAC1
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC119443 sequence for NM_001115 edited (data generated by NextGen Sequencing)
  ATGGAGCTCTCCGATGTGCGCTGCCTTACAGGCAGCGAGGAACTCTACACCATCCACCCG
  ACGCCCCCGGCCGGCGACGGCAGGAGCGCCTCCCGGCCGCAGCGGCTGCTGTGGCAGACG
  GCGGTGCGACACATCACGGAGCAGCGCTTCATTCACGGGCACCGGGGAGGCAGCGGCAGC
  GGGAGTGGAGGCTCGGGCAAAGCCTCGGACCCTGCGGGCGGCGGCCCCAACCACCACACG
  CCGCAGCTGTCAGGCGACTCGGCGCTGCCCCTCTACTCGCTGGGCCCGGGAGAGCGAGCG
  CACAGCACCTGCGGCACCAAAGTCTTCCCGGAACGCAGCGGGAGCGGCAGTGCCAGCGGC
  AGCGGAGGCGGGGGCGACCTGGGCTTCCTGCACCTTGACTGTGCCCCTAGCAACTCGGAT
  TTCTTTCTTAATGGGGGCTATAGCTACCGAGGGGTCATTTTCCCCACCCTGCGCAACTCC
  TTCAAATCTCGGGATTTGGAACGCCTCTACCAGCGCTATTTCTTGGGCCAAAGGCGCAAA
  TCGGAAGTGGTGATGAACGTGCTGGACGTGCTGACCAAACTCACTCTCTTGGTCCTACAC
  TTGAGCCTGGCCTCGGCCCCCATGGACCCGCTCAAGGGCATCCTGCTGGGCTTCTTCACC
  GGCATTGAGGTAGTGATCTGCGCCCTGGTGGTGGTCAGGAAGGACACCACCTCCCACACG
  TACCTGCAGTACAGCGGCGTGGTCACCTGGGTGGCCATGACCACCCAGATCCTGGCAGCA
  GGCCTCGGCTACGGGCTCCTGGGCGACGGCATAGGCTACGTGCTCTTCACGCTCTTCGCC
  ACCTACAGTATGCTGCCGCTGCCGCTCACCTGGGCCATCCTGGCCGGCCTGGGCACCTCG
  CTGCTGCAGGTCATCCTCCAAGTGGTCATACCCCGGCTGGCGGTCATTTCCATCAACCAG
  GTTGTGGCCCAGGCAGTGCTATTCATGTGTATGAACACAGCTGGAATCTTCATCAGTTAC
  CTGTCAGACCGTGCCCAGCGCCAAGCTTTCCTGGAGACTCGGAGGTGTGTGGAGGCCAGG
  CTGCGCCTGGAGACAGAGAACCAAAGACAGGAGCGGCTCGTGCTTTCTGTGCTCCCCCGG
  TTTGTTGTCCTGGAAATGATCAACGACATGACCAATGTGGAAGATGAGCACCTGCAGCAC
  CAGTTCCATCGGATCTACATCCATCGCTATGAGAACGTCAGTATTCTTTTTGCAGATGTT
  AAAGGATTTACCAACCTCTCCACGACCTTGTCTGCTCAGGAGCTGGTCAGGATGCTCAAC
  GAGCTCTTTGCCAGATTTGATCGACTGGCCCATGAGCATCACTGCCTTCGTATTAAAATC
  CTGGGGGACTGCTACTACTGCGTGTCTGGACTTCCTGAGCCCCGCCAGGACCATGCCCAC
  TGCTGTGTTGAAATGGGTCTCAGCATGATCAAAACCATCAGGTATGTGCGGTCAAGGACA
  AAACACGATGTTGACATGAGGATTGGAATCCACTCCGGCTCGGTGCTGTGCGGTGTTTTG
  GGACTAAGGAAGTGGCAGTTTGATGTCTGGTCTTGGGATGTGGATATTGCAAACAAACTC
  GAATCTGGAGGAATCCCTGGGAGGATTCACATTTCCAAAGCCACGCTGGACTGTCTCAAC
  GGTGACTATAACGTGGAAGAGGGCCATGGTAAAGAGAGGAATGAATTCCTGAGGAAGCAT
  AATATCGAAACTTACTTAATTAAGCAGCCTGAGGACAGTCTGCTGTCCTTGCCTGAAGAT
  ATCGTCAAGGAGTCAGTGAGCTCCTCAGACCGGAGAAACAGTGGGGCCACATTCACTGAA
  GGATCCTGGAGCCCTGAACTGCCCTTTGATAATATCGTGGGGAAACAGAATACTCTGGCT
  GCCCTAACAAGAAATTCAATAAATCTGCTTCCAAACCATCTTGCACAAGCTTTGCATGTC
  CAGTCTGGGCCTGAGGAAATTAACAAGAGAATAGAACATACCATCGACTTGCGGAGTGGC
  GATAAATTGAGAAGAGAGCATATCAAGCCATTCTCACTGATGTTTAAAGACTCCAGCCTG
  GAGCACAAGTATTCTCAAATGAGGGATGAAGTGTTCAAGTCAAACTTGGTCTGTGCATTT
  ATCGTTCTTCTATTTATCACGGCAATACAAAGTTTGCTTCCTTCTTCAAGAGTGATGCCA
  ATGACCATCCAGTTCTCCATTCTGATTATGCTGCACTCGGCTCTGGTCCTCATCACCACA
  GCAGAGGATTATAAATGTTTGCCCCTCATCCTCCGGAAAACTTGCTGTTGGATTAATGAG
  ACCTATTTGGCCCGGAACGTCATCATCTTTGCATCCATTTTGATTAATTTCCTGGGTGCC
  ATCTTAAATATCCTGTGGTGTGATTTTGACAAGTCGATACCCTTGAAGAACCTGACTTTC
  AATTCCTCAGCTGTGTTTACAGATATCTGCTCCTACCCAGAGTACTTTGTCTTCACGGGG
  GTGTTGGCCATGGTGACCTGTGCAGTTTTCCTCCGGCTGAACTCCGTCCTGAAGCTGGCA
  GTGCTGCTGATCATGATTGCCATCTATGCCCTGCTCACTGAGACCGTCTACGTAGGCCTC
  TTTCTGCGTTATGACAACCTCAACCACAGTGGAGAAGATTTCCTGGGGACCAAGGAGGTA
  TCACTGCTACTGATGGCCATGTTCCTCCTGGCTGTGTTCTACCATGGACAGCAGCTGGAG
  TACACAGCCCGCCTGGACTTCCTTTGGCGAGTACAGGCCAAAGAGGAGATCAATGAGATG
  AAGGAGCTGAGGGAACACAATGAGAACATGCTCCGGAATATCTTACCCAGCCATGTGGCC
  CGCCATTTCCTAGAGAAGGACCGAGACAATGAGGAGCTGTATTCTCAATCCTATGATGCT
  GTTGGGGTGATGTTTGCCTCCATCCCAGGATTTGCGGACTTTTACTCTCAGACTGAAATG
  AATAACCAGGGAGTGGAATGCCTGCGCTTGCTCAATGAGATCATTGCTGACTTCGATGAG
  TTGCTTGGTGAAGACCGATTTCAAGACATTGAAAAGATTAAGACCATTGGCAGCACCTAC
  ATGGCCGTGTCAGGCCTGTCACCTGAAAAACAGCAATGTGAAGACAAGTGGGGACATTTG
  TGTGCTCTGGCTGACTTCTCACTCGCCCTGACAGAAAGCATACAGGAGATCAACAAGCAT
  TCATTCAACAATTTTGAACTCCGGATTGGCATCAGCCACGGCTCAGTGGTAGCTGGCGTT
  ATCGGCGCTAAGAAACCACAGTATGACATTTGGGGCAAAACTGTGAACCTGGCAAGCCGA
  ATGGACAGCACGGGGGTTAGTGGCCGGATCCAAGTCCCAGAGGAGACCTATCTCATCCTG
  AAGGACCAGGGCTTTGCCTTTGATTACCGAGGGGAGATCTATGTGAAGGGTATCAGTGAA
  CAGGAAGGAAAAATCAAAACGTACTTTCTTCTGGGAAGAGTCCAACCCAACCCATTCATC
  TTGCCCCCAAGAAGACTGCCTGGGCAGTACTCCCTGGCCGCGGTTGTCCTGGGACTTGTC
  CAGTCCCTCAATAGGCAAAGGCAGAAGCAGCTACTCAATGAGAACAACAACACAGGAATC
  ATCAAGGGTCATTACAACCGGCGGACTTTGTTGTCACCCAGCGGCACAGAGCCTGGAGCC
  CAGGCTGAAGGCACCGACAAATCTGATTTGCCATAA
  
  Clone variation with respect to NM_001115.2
  238 g=>a;1032 g=>t;2633 c=>t
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001115 unedited
  AACGTCAGCCGCCCGTTCNCGCTAATGGGCGTAGGCGTGTACGGTGGGAGGTCTATATAA
  GCAGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCG
  CGAATTCGGCACGAGGCCCAAGCTGCGCCGGCTGGCGGGAGAGCAGCACGCAAGGACGCC
  GAGGTCCGCCGCGATCTTCCAGGTGCCCTTTGCCCCTGGGCACAGTATGACCCGACCTAC
  AGGGAGCCCTAGCGCAGGGCTCCTGCAACGGGGCAGCCTAGGATAAAAAGGATCCTTGCC
  AAGCTCCTACCAGGCCGCCTTTGAGTCTTTAGGAACCCCTCCTCCGGCTGCCTCCCCAAG
  GTTCTGGGCCTCCTTCCCTGCGGCCCAGAGCCATGGAGCTCTCCGATGTGCGCTGCCTTA
  CAGGCAGCGAGGAACTCTACACCATCCACCCGACGCCCCCGGCCGGCGACGGCAGGAGCG
  CCTCCCGGCCGCAGCGGCTGCTGTGGCAGACGGCGGTGCGACACATCACGGAGCAGCGCT
  TCATTCACGGGCACCGGGGAGGCAGCGGCAGCGGGAGTGGAGGCTCGGGCAAAGCCTCGG
  ACCCTGCGGGCGGCGGCCCCAACCACCACACGCCGCAGCTGTCAGGCGACTCGGCGCTGC
  CCCTCTACTCGCTGGGCCCGGGAGAGCGAGCGCACAGCACCTGCGGCACCAAAGTCTTCC
  CGGAACGCAGCGGGAGCGGCAGTGCCAGCGGCAGCGGAAGCGGGGGCGACCTGNGCTTCC
  TGCACCTTGACTGTGCCCCTAGCAACTCGGATTTCTTTCTTAATGGGGGCTATAGCTACC
  CGAGGGTCATTTTCCCCCCCTGCGCACTCCTTCAATCTCGGGATTGGAACGCCTCTACCA
  GCGCTATT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001115 unedited
  AGNGTGGCACTGGGGNGGGGTCACAGGGCTGCCACCCGGGCTCTGTTCAGGAAACAGCTA
  TGACCGCGGCCGCAATCTATAGTCGAGTTTTTTTTTTTTTTTTTTCTAAAAAAAATTAAA
  CCTTTTTATTAGTATATTTATTTTATATATAAAAGAAATACAAAAAAAAAAAAAACAGAA
  AGAAAATGCTTTTATGGCAAATCAGATTTGTCGGTGCCTTCAGCCTGGGCTCCAGGCTCT
  GTGCCGCTGGGTGACAACAAAGTCCGCCGGTTGTAATGACCCTTGATGATTCCTGTGTTG
  TTGTTCTCATTGAGTAGCTGCTTCTGCCTTTGCCTATTGAGGGACTGGACAAGTCCCAGG
  ACAACCGCGGCCAGGGAGTACTGCCCAGGCAGTCTTCTTGGGGGCAAGATGAATGGGTTG
  GGTTGGACTCTTCCCAGAAGAAAGTACGTTTTGATTTTTCCTTCCTGTTCACTGATACCC
  TTCACATAGATCTCCCCTCGGTAATCAAAGGCAAAGCCCTGGTCCTTCAGGATGAGATAG
  GTCTCCTCTGGGACTTGGATCCGGCCACTAACCCCCGTGCTGTCCATTCGGCTTGCCAGG
  TTCACAGTTTTGCCCCAAATGTCATACTGTGGTTTCTTAGCGCCGATAACGCCAGCTACC
  ACTGAGCCGTGGCTGATGCCAATCCGGAGTTCAAAATTGTAGAATGAATGCTTGTTGATC
  TCCTGTATGCTTTCTGTCAGGGCGAGTGAGAAGTCAGCCAGAGCACACAAATGTCCCCAC
  TTGGTCTCACATTGCTGTTTTTTAAGTGACAGGCCTGACACGGCCATGTAGGTGCTGCAA
  GGGTCTTATCCTTTCATGTCNTGAAATGGGTCTTAACCAGCACTCATCGAG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_001115
• ORF Size: 3756 bp
• Insert Size: 4700
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001115.1, NP_001106.1
• RefSeq Size: 6005
• RefSeq ORF: 3756
• Locus ID: 114
• Domains: CYCc
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Calcium signaling pathway, Chemokine signaling pathway, Dilated cardiomyopathy, Gap junction, GnRH signaling pathway, Long-term potentiation, Melanogenesis, Oocyte meiosis, Progesterone-mediated oocyte maturation, Purine metabolism, Taste transduction, Vascular smooth muscle contraction
• Gene Summary: Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several hormones, and different polypeptides participate in the transduction of the signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (Rs and Ri) interact with G proteins (Gs and Gi) that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the adenylyl cyclase [provided by RefSeq, Jul 2008]