Integrin beta 7 (ITGB7) (NM_000889) Human Untagged Clone

CAT#: SC119589

ITGB7 (untagged)-Human integrin, beta 7 (ITGB7)


  "NM_000889" in other vectors (6)

Reconstitution Protocol

USD 310.00

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol ITGB7
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_000889 edited
GAATTCGGCACGAGGCAGAGGAAGGACTGCTCTGCACGCACCTATGTGGAAACTAAAGCC
CAGAGAGAAAGTCTGACTTGCCCCACAGCCAGTGAGTGACTGCAGCAGCACCAGAATCTG
GTCTGTTTCCTGTTTGGCTCTTCTACCACTACGGCTTGGGATCTCGGGCATGGTGGCTTT
GCCAATGGTCCTTGTTTTGCTGCTGGTCCTGAGCAGAGGTGAGAGTGAATTGGACGCCAA
GATCCCATCCACAGGGGATGCCACAGAATGGCGGAATCCTCACCTGTCCATGCTGGGGTC
CTGCCAGCCAGCCCCCTCCTGCCAGAAGTGCATCCTCTCACACCCCAGCTGTGCATGGTG
CAAGCAACTGAACTTCACCGCGTCGGGAGAGGCGGAGGCGCGGCGCTGCGCCCGACGAGA
GGAGCTGCTGGCTCGAGGCTGCCCGCTGGAGGAGCTGGAGGAGCCCCGCGGCCAGCAGGA
GGTGCTGCAGGACCAGCCGCTCAGCCAGGGCGCCCGCGGAGAGGGTGCCACCCAGCTGGC
GCCGCAGCGGGTCCGGGTCACGCTGCGGCCTGGGGAGCCCCAGCAGCTCCAGGTCCGCTT
CCTTCGTGCTGAGGGATACCCGGTGGACCTGTACTACCTTATGGACCTGAGCTACTCCAT
GAAGGACGACCTGGAACGCGTGCGCCAGCTCGGGCACGCTCTGCTGGTCCGGCTGCAGGA
AGTCACCCATTCTGTGCGCATTGGTTTTGGTTCCTTTGTGGACAAAACGGTGCTGCCCTT
TGTGAGCACAGTACCCTCCAAACTGCGCCACCCCTGCCCCACCCGGCTGGAGCGCTGCCA
GTCACCATTCAGCTTTCACCATGTGCTGTCCCTGACGGGGGACGCACAAGCCTTCGAGCG
GGAGGTGGGGCGCCAGAGTGTGTCCGGCAATCTGGACTCGCCTGAAGGTGGCTTCGATGC
CATTCTGCAGGCTGCACTCTGCCAGGAGCAGATTGGCTGGAGAAATGTGTCCCGGCTGCT
GGTGTTCACTTCAGACGACACATTCCATACAGCTGGGGACGGGAAGTTGGGCGGCATTTT
CATGCCCAGTGATGGGCACTGCCACTTGGACAGCAATGGCCTCTACAGTCGCAGCACAGA
GTTTGACTACCCTTCTGTGGGTCAGGTAGCCCAGGCCCTCTCTGCAGCAAATATCCAGCC
CATCTTTGCTGTCACCAGTGCCGCACTGCCTGTCTACCAGGAGCTGAGTAAACTGATTCC
TAAGTCTGCAGTTGGGGAGCTGAGTGAGGACTCCAGCAACGTGGTACAGCTCATCATGGA
TGCTTATAATAGCCTGTCTTCCACCGTGACCCTTGAACACTCTTCACTCCCTCCTGGGGT
CCACATTTCTTACGAATCCCAGTGTGAGGGTCCTGAGAAGAGGGAGGGTAAGGCTGAGGA
TCGAGGACAGTGCAACCACGTCCGAATCAACCAGACGGTGACTTTCTGGGTTTCTCTCCA
AGCCACCCACTGCCTCCCAGAGCCCCATCTCCTGAGGCTCCGGGCCCTTGGCTTCTCAGA
GGAGCTGATTGTGGAGTTGCACACGCTGTGTGACTGTAATTGCAGTGACACCCAGCCCCA
GGCTCCCCACTGCAGTGATGGCCAGGGACACCTACAATGTGGTGTATGCAGCTGTGCCCC
TGGCCGCCTAGGTCGGCTCTGTGAGTGCTCTGTGGCAGAGCTGTCCTCCCCAGACCTGGA
ATCTGGGTGCCGGGCTCCCAATGGCACAGGGCCCCTGTGCAGTGGAAAGGGTCACTGTCA
ATGTGGACGCTGCAGCTGCAGTGGACAGAGCTCTGGGCATCTGTGCGAGTGTGACGATGC
CAGCTGTGAGCGACATGAGGGCATCCTCTGCGGAGGCTTTGGTCGCTGCCAATGTGGAGT
ATGTCACTGTCATGCCAACCGCACGGGCAGAGCATGCGAATGCAGTGGGGACATGGACAG
TTGCATCAGTCCCGAGGGAGGGCTCTGCAGTGGGCATGGACGCTGCAAATGCAACCGCTG
CCAGTGCTTGGACGGCTACTATGGTGCTCTATGCGACCAATGCCCAGGCTGCAAGACACC
ATGCGAGAGACACCGGGACTGTGCAGAGTGTGGGGCCTTCAGGACTGGCCCACTGGCCAC
CAACTGCAGTACAGCTTGTGCCCATACCAATGTGACCCTGGCCTTGGCCCCTATCTTGGA
TGATGGCTGGTGCAAAGAGCGGACCCTGGACAACCAGCTGTTCTTCTTCTTGGTGGAGGA
TGACGCCAGAGGCACGGTCGTGCTCAGAGTGAGACCCCAAGAAAAGGGAGCAGACCACAC
GCAGGCCATTGTGCTGGGCTGCGTAGGGGGCATCGTGGCAGTGGGGCTGGGGCTGGTCCT
GGCTTACCGGCTCTCGGTGGAAATCTATGACCGCCGGGAATACAGTCGCTTTGAGAAGGA
GCAGCAACAACTCAACTGGAAGCAGGACAGTAATCCTCTCTACAAAAGTGCCATCACGAC
CACCATCAATCCTCGCTTTCAAGAGGCAGACAGTCCCACTCTCTGAAGGAGGGAGGGACA
CTTACCCAAGGCTCTTCTCCTTGGAGGACAGTGGGAACTGGAGGGTGAGAGGAAGGGTGG
GTCTGTAAGACCTTGGTAGGGGACTAATTCACTGGCGAGGTGCGGCCACCACCCTACTTC
ATTTTCAGAGTGACACCCAAGAGGGCTGCTTCCCATGCCTGCAACCTTGCATCCATCTGG
GCTACCCCACCCAAGTATACAATAAAGTCTTACCTCAGAAAAAAAAAAAAAAAAAAAAAA
CTCGAC
>OriGene 5' read for NM_000889 unedited
ATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCAGAGGAAGGACTGCTCTGC
ACGCACCTATGTGGAAACTAAAGCCCAGAGAGAAAGTCTGACTTGCCCCACAGCCAGTGA
GTGACTGCAGCAGCACCAGAATCTGGTCTGTTTCCTGTTTGGCTCTTCTACCACTACGGC
TTGGGATCTCGGGCATGGTGGCTTTGCCAATGGTCCTTGTTTTGCTGCTGGTCCTGAGCA
GAGGTGAGAGTGAATTGGACGCCAAGATCCCATCCACAGGGGATGCCACAGAATGGCGGA
ATCCTCACCTGTCCATGCTGGGGTCCTGCCAGCCAGCCCCCTCCTGCCAGAAGTGCATCC
TCTCACACCCCAGCTGTGCATGGTGCAAGCAACTGAACTTCACCGCGTCGGGAGAGGCGG
AGGCGCGGCGCTGCGCCCGACGAGAGGAGCTGCTGGCTCGAGGCTGCCCGCTGGAGGAGC
TGGAGGAGCCCCGCGGCCAGCAGGAGGTGCTGCAGGACCAGCCGCTCAGCCAGGGCGCCC
GCGGAGAGGGTGCCACCCAGCTGGCGCCGCAGCGGGTCCGGGTCACGCTGCGGCCTGGGG
AGCCCCAGCAGCTCCAGGTCCGCTTCCTTCGTGCTGAGGGATACCCGGTGGACCTGTACT
ACCTTATGGACCTGAGCTACTCCATGAAGGACGACCTGNAACGCGTGCGCCAGCTCGGGC
ACGCTCTGCTGGTCCGGCTGCANGAAGTCACCCATTCTGTGCGCATTGGGTTNTGGTTCC
TTTGTGGGACAAACGGTGCTGNCCTTTGTGAGCACAGTACCCTTCAACTGCGCCACCCTG
CCCANCCGGCTGAGCGCTGCCGTCACATTCAGTTTCCCATGTGCTGTCCCCTGACGGGGA
CGCACAGCTTCAACGGGGAGGTGGGCCCCNAAATGTGTCCGCATCTGACTNCCCTGAANG
>OriGene 3' read for NM_000889 unedited
CGCGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTCTGAGGTAAGACTTTA
TTGTATACTTGGGTGGGGTAGCCCAGATGGATGCAAGGTTGCAGGCATGGGAAGCAGCCC
TCTTGGGTGTCACTCTGAAAATGAAGTAGGGTGGTGGCCGCACCTCGCCAGTGAATTAGT
CCCCTACCAAGGTCTTACAGACCCACCCTTCCTCTCACCCTCCAGTTCCCACTGTCCTCC
AAGGAGAAGAGCCTTGGGTAAGTGTCCCTCCCTCCTTCAGAGAGTGGGACTGTCTGCCTC
TTGAAAGCGAGGATTGATGGTGGTCGTGATGGCACTTTTGTAGAGAGGATTACTGTCCTG
CTTCCAGTTGAGTTGTTGCTGCTCCTTCTCAAAGCGACTGTATTCCCGGCGGTCATAGAT
TTCCACCGAGAGCCGGTAAGCCAGGACCAGCCCCAGCCCCACTGCCACGATGCCCCCTAC
GCAGCCCAGCACAATGGCCTGCGTGTGGTCTGCTCCCTTTTCTTGGGGTCTCACTCTGAG
CACGACCGTGCCTCTGGCGTCATCCTCCACCAAGAAGAAGAACAGCTGGTTGTCCAGGGT
CCGCTCTTTGCACCAGCCATCATCCAAGATAGGGGCCAAGGCCAGGGTCACATTGGTATG
GGCACAAGCTGTACTGCATTTGTTGGCCAGTGGGCCAGTTCTTGAGGCCCCCACTCTGCA
CAGTTCCCGTGTCTCTCGCATGGTGTTTTGCACCCTGCGCCTTGTTCGCATAAAGCACCA
TATTACCCGTTCAAGCACTCGCAGGGGTTTGATTTGGCACGTCCTTGCCCACTGAAAGCC
TCCCTCGGGACTGTGGCACCGTTCATGTCCCCCTTGATTCGCATGCTTTGCCCTGCGGTT
GAATGAAAGGACATACTCACTTGGAGCGACCAAGCTCCGCAAGATGCCCTTTGTGTCAAT
TGATATGTACACTGCCAA
Restriction Sites NotI-NotI     
ACCN NM_000889
Insert Size 2500 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_000889.1, NP_000880.1
RefSeq Size 2798 bp
RefSeq ORF 2397 bp
Locus ID 3695
Cytogenetics 12q13.13
Domains INB, PSI
Protein Families Druggable Genome, Transmembrane
Protein Pathways Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cell adhesion molecules (CAMs), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Regulation of actin cytoskeleton
Gene Summary 'This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms dimers with an alpha4 chain or an alphaE chain and plays a role in leukocyte adhesion. Dimerization with alpha4 forms a homing receptor for migration of lymphocytes to the intestinal mucosa and Peyer's patches. Dimerization with alphaE permits binding to the ligand epithelial cadherin, a calcium-dependent adhesion molecule. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Sep 2013]'
Transcript Variant: This variant (1) represents the longer transcript.

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