Integrin beta 7 (ITGB7) (NM_000889) Human Untagged Clone
Product Images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Symbol | ITGB7 |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene sequence for NM_000889 edited
GAATTCGGCACGAGGCAGAGGAAGGACTGCTCTGCACGCACCTATGTGGAAACTAAAGCC CAGAGAGAAAGTCTGACTTGCCCCACAGCCAGTGAGTGACTGCAGCAGCACCAGAATCTG GTCTGTTTCCTGTTTGGCTCTTCTACCACTACGGCTTGGGATCTCGGGCATGGTGGCTTT GCCAATGGTCCTTGTTTTGCTGCTGGTCCTGAGCAGAGGTGAGAGTGAATTGGACGCCAA GATCCCATCCACAGGGGATGCCACAGAATGGCGGAATCCTCACCTGTCCATGCTGGGGTC CTGCCAGCCAGCCCCCTCCTGCCAGAAGTGCATCCTCTCACACCCCAGCTGTGCATGGTG CAAGCAACTGAACTTCACCGCGTCGGGAGAGGCGGAGGCGCGGCGCTGCGCCCGACGAGA GGAGCTGCTGGCTCGAGGCTGCCCGCTGGAGGAGCTGGAGGAGCCCCGCGGCCAGCAGGA GGTGCTGCAGGACCAGCCGCTCAGCCAGGGCGCCCGCGGAGAGGGTGCCACCCAGCTGGC GCCGCAGCGGGTCCGGGTCACGCTGCGGCCTGGGGAGCCCCAGCAGCTCCAGGTCCGCTT CCTTCGTGCTGAGGGATACCCGGTGGACCTGTACTACCTTATGGACCTGAGCTACTCCAT GAAGGACGACCTGGAACGCGTGCGCCAGCTCGGGCACGCTCTGCTGGTCCGGCTGCAGGA AGTCACCCATTCTGTGCGCATTGGTTTTGGTTCCTTTGTGGACAAAACGGTGCTGCCCTT TGTGAGCACAGTACCCTCCAAACTGCGCCACCCCTGCCCCACCCGGCTGGAGCGCTGCCA GTCACCATTCAGCTTTCACCATGTGCTGTCCCTGACGGGGGACGCACAAGCCTTCGAGCG GGAGGTGGGGCGCCAGAGTGTGTCCGGCAATCTGGACTCGCCTGAAGGTGGCTTCGATGC CATTCTGCAGGCTGCACTCTGCCAGGAGCAGATTGGCTGGAGAAATGTGTCCCGGCTGCT GGTGTTCACTTCAGACGACACATTCCATACAGCTGGGGACGGGAAGTTGGGCGGCATTTT CATGCCCAGTGATGGGCACTGCCACTTGGACAGCAATGGCCTCTACAGTCGCAGCACAGA GTTTGACTACCCTTCTGTGGGTCAGGTAGCCCAGGCCCTCTCTGCAGCAAATATCCAGCC CATCTTTGCTGTCACCAGTGCCGCACTGCCTGTCTACCAGGAGCTGAGTAAACTGATTCC TAAGTCTGCAGTTGGGGAGCTGAGTGAGGACTCCAGCAACGTGGTACAGCTCATCATGGA TGCTTATAATAGCCTGTCTTCCACCGTGACCCTTGAACACTCTTCACTCCCTCCTGGGGT CCACATTTCTTACGAATCCCAGTGTGAGGGTCCTGAGAAGAGGGAGGGTAAGGCTGAGGA TCGAGGACAGTGCAACCACGTCCGAATCAACCAGACGGTGACTTTCTGGGTTTCTCTCCA AGCCACCCACTGCCTCCCAGAGCCCCATCTCCTGAGGCTCCGGGCCCTTGGCTTCTCAGA GGAGCTGATTGTGGAGTTGCACACGCTGTGTGACTGTAATTGCAGTGACACCCAGCCCCA GGCTCCCCACTGCAGTGATGGCCAGGGACACCTACAATGTGGTGTATGCAGCTGTGCCCC TGGCCGCCTAGGTCGGCTCTGTGAGTGCTCTGTGGCAGAGCTGTCCTCCCCAGACCTGGA ATCTGGGTGCCGGGCTCCCAATGGCACAGGGCCCCTGTGCAGTGGAAAGGGTCACTGTCA ATGTGGACGCTGCAGCTGCAGTGGACAGAGCTCTGGGCATCTGTGCGAGTGTGACGATGC CAGCTGTGAGCGACATGAGGGCATCCTCTGCGGAGGCTTTGGTCGCTGCCAATGTGGAGT ATGTCACTGTCATGCCAACCGCACGGGCAGAGCATGCGAATGCAGTGGGGACATGGACAG TTGCATCAGTCCCGAGGGAGGGCTCTGCAGTGGGCATGGACGCTGCAAATGCAACCGCTG CCAGTGCTTGGACGGCTACTATGGTGCTCTATGCGACCAATGCCCAGGCTGCAAGACACC ATGCGAGAGACACCGGGACTGTGCAGAGTGTGGGGCCTTCAGGACTGGCCCACTGGCCAC CAACTGCAGTACAGCTTGTGCCCATACCAATGTGACCCTGGCCTTGGCCCCTATCTTGGA TGATGGCTGGTGCAAAGAGCGGACCCTGGACAACCAGCTGTTCTTCTTCTTGGTGGAGGA TGACGCCAGAGGCACGGTCGTGCTCAGAGTGAGACCCCAAGAAAAGGGAGCAGACCACAC GCAGGCCATTGTGCTGGGCTGCGTAGGGGGCATCGTGGCAGTGGGGCTGGGGCTGGTCCT GGCTTACCGGCTCTCGGTGGAAATCTATGACCGCCGGGAATACAGTCGCTTTGAGAAGGA GCAGCAACAACTCAACTGGAAGCAGGACAGTAATCCTCTCTACAAAAGTGCCATCACGAC CACCATCAATCCTCGCTTTCAAGAGGCAGACAGTCCCACTCTCTGAAGGAGGGAGGGACA CTTACCCAAGGCTCTTCTCCTTGGAGGACAGTGGGAACTGGAGGGTGAGAGGAAGGGTGG GTCTGTAAGACCTTGGTAGGGGACTAATTCACTGGCGAGGTGCGGCCACCACCCTACTTC ATTTTCAGAGTGACACCCAAGAGGGCTGCTTCCCATGCCTGCAACCTTGCATCCATCTGG GCTACCCCACCCAAGTATACAATAAAGTCTTACCTCAGAAAAAAAAAAAAAAAAAAAAAA CTCGAC >OriGene 5' read for NM_000889 unedited
ATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCAGAGGAAGGACTGCTCTGC ACGCACCTATGTGGAAACTAAAGCCCAGAGAGAAAGTCTGACTTGCCCCACAGCCAGTGA GTGACTGCAGCAGCACCAGAATCTGGTCTGTTTCCTGTTTGGCTCTTCTACCACTACGGC TTGGGATCTCGGGCATGGTGGCTTTGCCAATGGTCCTTGTTTTGCTGCTGGTCCTGAGCA GAGGTGAGAGTGAATTGGACGCCAAGATCCCATCCACAGGGGATGCCACAGAATGGCGGA ATCCTCACCTGTCCATGCTGGGGTCCTGCCAGCCAGCCCCCTCCTGCCAGAAGTGCATCC TCTCACACCCCAGCTGTGCATGGTGCAAGCAACTGAACTTCACCGCGTCGGGAGAGGCGG AGGCGCGGCGCTGCGCCCGACGAGAGGAGCTGCTGGCTCGAGGCTGCCCGCTGGAGGAGC TGGAGGAGCCCCGCGGCCAGCAGGAGGTGCTGCAGGACCAGCCGCTCAGCCAGGGCGCCC GCGGAGAGGGTGCCACCCAGCTGGCGCCGCAGCGGGTCCGGGTCACGCTGCGGCCTGGGG AGCCCCAGCAGCTCCAGGTCCGCTTCCTTCGTGCTGAGGGATACCCGGTGGACCTGTACT ACCTTATGGACCTGAGCTACTCCATGAAGGACGACCTGNAACGCGTGCGCCAGCTCGGGC ACGCTCTGCTGGTCCGGCTGCANGAAGTCACCCATTCTGTGCGCATTGGGTTNTGGTTCC TTTGTGGGACAAACGGTGCTGNCCTTTGTGAGCACAGTACCCTTCAACTGCGCCACCCTG CCCANCCGGCTGAGCGCTGCCGTCACATTCAGTTTCCCATGTGCTGTCCCCTGACGGGGA CGCACAGCTTCAACGGGGAGGTGGGCCCCNAAATGTGTCCGCATCTGACTNCCCTGAANG >OriGene 3' read for NM_000889 unedited
CGCGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTCTGAGGTAAGACTTTA TTGTATACTTGGGTGGGGTAGCCCAGATGGATGCAAGGTTGCAGGCATGGGAAGCAGCCC TCTTGGGTGTCACTCTGAAAATGAAGTAGGGTGGTGGCCGCACCTCGCCAGTGAATTAGT CCCCTACCAAGGTCTTACAGACCCACCCTTCCTCTCACCCTCCAGTTCCCACTGTCCTCC AAGGAGAAGAGCCTTGGGTAAGTGTCCCTCCCTCCTTCAGAGAGTGGGACTGTCTGCCTC TTGAAAGCGAGGATTGATGGTGGTCGTGATGGCACTTTTGTAGAGAGGATTACTGTCCTG CTTCCAGTTGAGTTGTTGCTGCTCCTTCTCAAAGCGACTGTATTCCCGGCGGTCATAGAT TTCCACCGAGAGCCGGTAAGCCAGGACCAGCCCCAGCCCCACTGCCACGATGCCCCCTAC GCAGCCCAGCACAATGGCCTGCGTGTGGTCTGCTCCCTTTTCTTGGGGTCTCACTCTGAG CACGACCGTGCCTCTGGCGTCATCCTCCACCAAGAAGAAGAACAGCTGGTTGTCCAGGGT CCGCTCTTTGCACCAGCCATCATCCAAGATAGGGGCCAAGGCCAGGGTCACATTGGTATG GGCACAAGCTGTACTGCATTTGTTGGCCAGTGGGCCAGTTCTTGAGGCCCCCACTCTGCA CAGTTCCCGTGTCTCTCGCATGGTGTTTTGCACCCTGCGCCTTGTTCGCATAAAGCACCA TATTACCCGTTCAAGCACTCGCAGGGGTTTGATTTGGCACGTCCTTGCCCACTGAAAGCC TCCCTCGGGACTGTGGCACCGTTCATGTCCCCCTTGATTCGCATGCTTTGCCCTGCGGTT GAATGAAAGGACATACTCACTTGGAGCGACCAAGCTCCGCAAGATGCCCTTTGTGTCAAT TGATATGTACACTGCCAA |
Restriction Sites | NotI-NotI |
ACCN | NM_000889 |
Insert Size | 2500 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones. |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_000889.1, NP_000880.1 |
RefSeq Size | 2798 bp |
RefSeq ORF | 2397 bp |
Locus ID | 3695 |
Cytogenetics | 12q13.13 |
Domains | INB, PSI |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cell adhesion molecules (CAMs), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Regulation of actin cytoskeleton |
Gene Summary | 'This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms dimers with an alpha4 chain or an alphaE chain and plays a role in leukocyte adhesion. Dimerization with alpha4 forms a homing receptor for migration of lymphocytes to the intestinal mucosa and Peyer's patches. Dimerization with alphaE permits binding to the ligand epithelial cadherin, a calcium-dependent adhesion molecule. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Sep 2013]' Transcript Variant: This variant (1) represents the longer transcript. |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC204193 | ITGB7 (Myc-DDK-tagged)-Human integrin, beta 7 (ITGB7) |
USD 610.00 |
|
RG204193 | ITGB7 (GFP-tagged) - Human integrin, beta 7 (ITGB7) |
USD 670.00 |
|
RC204193L1 | Lenti ORF clone of Human integrin, beta 7 (ITGB7), Myc-DDK-tagged |
USD 1,008.00 |
|
RC204193L2 | Lenti ORF clone of Human integrin, beta 7 (ITGB7), mGFP tagged |
USD 1,008.00 |
|
RC204193L3 | Lenti ORF clone of Human integrin, beta 7 (ITGB7), Myc-DDK-tagged |
USD 810.00 |
|
RC204193L4 | Lenti ORF clone of Human integrin, beta 7 (ITGB7), mGFP tagged |
USD 810.00 |
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