ICAM2 (NM_000873) Human Untagged Clone

CAT#: SC119621

ICAM2 (untagged)-Human intercellular adhesion molecule 2 (ICAM2), transcript variant 5

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ICAM2
• Synonyms: CD102
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC119621 sequence for NM_000873 edited (data generated by NextGen Sequencing)
  ATGTCCTCTTTCGGTTACAGGACCCTGACTGTGGCCCTCTTCACCCTGATCTGCTGTCCA
  GGATCGGATGAGAAGGTATTCGAGGTACACGTGAGGCCAAAGAAGCTGGCGGTTGAGCCC
  AAAGGGTCCCTCGAGGTCAACTGCAGCACCACCTGTAACCAGCCTGAAGTGGGTGGTCTG
  GAGACCTCTCTAGATAAGATTCTGCTGGACGAACAGGCTCAGTGGAAACATTACTTGGTC
  TCAAACATCTCCCATGACACGGTCCTCCAATGCCACTTCACCTGCTCCGGGAAGCAGGAG
  TCAATGAATTCCAACGTCAGCGTGTACCAGCCTCCAAGGCAGGTCATCCTGACACTGCAA
  CCCACTTTGGTGGCTGTGGGCAAGTCCTTCACCATTGAGTGCAGGGTGCCCACCGTGGAG
  CCCCTGGACAGCCTCACCCTCTTCCTGTTCCGTGGCAATGAGACTCTGCACTATGAGACC
  TTCGGGAAGGCAGCCCCTGCTCCGCAGGAGGCCACAGCCACATTCAACAGCACGGCTGAC
  AGAGAGGATGGCCACCGCAACTTCTCCTGCCTGGCTGTGCTGGACTTGATGTCTCGCGGT
  GGCAACATCTTTCACAAACACTCAGCCCCGAAGATGTTGGAGATCTATGAGCCTGTGTCG
  GACAGCCAGATGGTCATCATAGTCACGGTGGTGTCGGTGTTGCTGTCCCTGTTCGTGACA
  TCTGTCCTGCTCTGCTTCATCTTCGGCCAGCACTTGCGCCAGCAGCGGATGGGCACCTAC
  GGGGTGCGAGCGGCTTGGAGGAGGCTGCCCCAGGCCTTCCGGCCATAG
  
  Clone variation with respect to NM_000873.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000873 unedited
  NCCCTCTATCCCCCGCCCCTTGCCGCAAAGGGCGGTAGGCGTGTACGGTGGGAGGTCTAT
  ATAAGCAGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCG
  GCCGCGAATTCGGCACGAGGGGCAGCCCTTGGCTGGTCCCTGCGAGCCCGTGGAGACTGC
  CAGAGATGTCCTCTTTCGGTTACAGGACCCTGACTGTGGCCCTCTTCACCCTGATCTGCT
  GTCCAGGATCGGATGAGAAGGTATTCGAGGTACACGTGAGGCCAAAGAAGCTGGCGGTTG
  AGCCCAAAGGGTCCCTCGAGGTCAACTGCAGCACCACCTGTAACCAGCCTGAAGTGGGTG
  GTCTGGAGACCTCTCTAGATAAGATTCTGCTGGACGAACAGGCTCAGTGGAAACATTACT
  TGGTCTCAAACATCTCCCATGACACGGTCCTCCAATGCCACTTCACCTGCTCCGGGAAGC
  AGGAGTCAATGAATTCCAACGTCAGCGTGTACCAGCCTCCAAGGCAGGTCATCCTGACAC
  TGCAACCCACTTTGGTGGCTGTGGGCAAGTCCTTCACCATTGAGTGCAGGGTGCCCACCG
  TGGAGCCCCTGGACAGCCTCACCCTCTTCCTGTTCCGTGGCAATGAGACTCTGCACTATG
  AGACCTTCGGGAAGGCAGCCCCTGCTCCGCAGGAGGCCACAGCCACATTCAACAGCACGG
  CTGACAGAGAGGATGGCCACCGCAACTTCTCCTGCCTGGCTGTGCTGGACTTGATGTCTC
  GCGGTGGCAACATCTTTCACAACACTCAGCCCCGAAGATGTTGGAGATCTATGAGCCTGT
  GTCNGACAGCCAGATGGTCATCATAGTCACGGTGGGTGTCGGTGTTGCTGTCCCTGTTA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000873 unedited
  NNNNGGGCTCATAGCTATGNNACCGCGGCCGCATNCTAGGATCGAGTTTTTTTTTTTTTT
  TTTTAAGTCCAGGTGTTTGTATTCGGGCTAGAAAAGCAATGTCCCAAGTCTCTGCTGCCT
  GTCACAGTCCTTCAGCCAGGGCTGGACCTCAACCCTGAGGAGTCACACTGAGTTCCAGTG
  ACCACCGTGGTGGTGGCCATGCCACTCATGGTTGCTATGGCCGGAAGGCCTGGGGCAGCC
  TCCTCCAAGCCGCTCGCACCCCGTAGGTGCCCATCCGCTGCTGGCGCAAGTGCTGGCCGA
  AGATGAAGCAGAGCAGGACAGATGTCACGAACAGGGACAGCAACACCGACACCACCGTGA
  CTATGATGACCATCTGGCTGTCCGACACAGGCTCATAAATCTCCAACATCTTCGGGGCTG
  AGTGTTTGTGAAAGATGTTGCCACCGCGAGACATCAAGTCCAGCACAGCCAGGCAAGAAA
  AGTTGCGGTGGCCATCCTCCTTGTCAACCCGGCTGTTGAATGTGGGTGTGGCCTCCTGCG
  GAACAGGGCTGGCCTCCGAACTGTCTATAATGCAGAGTCTTCTTTCCCCGGAACAGGAAA
  AGGGGGAGGCTTGCCCAGGGGTCCAACGGGGGCCACCCTGGCCTTTAATGGTGAAGGAAT
  TTGCCACAACCACCCACAATGGGGTTGTAGTGGTCCGGATGAACCCGGATTTGGAAGTTT
  AGAAACCCCCTGTCTTTTGCAATCGATTGGCCTCCTCGCTTCCCGAGGCCAGTTGAAATG
  GAATTTGGAACGAACCCGATTATGGGAAAATTGTTTAAAACCCAACACGGGATTTCACAT
  GACGCCGTGGTATCCCCGCCCAATTTTTTTTCTTTAACGGGGGCTTTAGAACAC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_000873
• Insert Size: 1000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000873.2, NP_000864.1
• RefSeq Size: 1035 bp
• RefSeq ORF: 828 bp
• Locus ID: 3384
• Cytogenetics: 17q23.3
• Domains: ICAM_N
• Protein Families: ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Natural killer cell mediated cytotoxicity
• Gene Summary: 'The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. All 5 variants encode the same protein.