GAS 6 (GAS6) (NM_000820) Human Untagged Clone

CAT#: SC119633

GAS6 (untagged)-Human growth arrest-specific 6 (GAS6), transcript variant 1


  "NM_000820" in other vectors (6)

Reconstitution Protocol

USD 310.00

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol GAS6
Synonyms AXLLG; AXSF
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC119633 sequence for NM_000820 edited (data generated by NextGen Sequencing)
ATGGCCCCTTCGCTCTCGCCCGGGCCCGCCGCCCTGCGCCGCGCGCCGCAGCTGCTGCTG
CTGCTGCTGGCCGCGGAGTGCGCGCTTGCCGCGCTGTTGCCGGCGCGCGAGGCCACGCAG
TTCCTGCGGCCCAGGCAGCGCCGCGCCTTTCAGGTCTTCGAGGAGGCCAAGCAGGGCCAC
CTGGAGAGGGAGTGCGTGGAGGAGCTGTGCAGCCGCGAGGAGGCGCGGGAGGTGTTCGAG
AACGACCCCGAGACGGATTATTTTTACCCAAGATACTTAGACTGCATCAACAAGTATGGG
TCTCCGTACACCAAAAACTCAGGCTTCGCCACCTGCGTGCAAAACCTGCCTGACCAGTGC
ACGCCCAACCCCTGCGATAGGAAGGGGACCCAAGCCTGCCAGGACCTCATGGGCAACTTC
TTCTGCCTGTGTAAAGCTGGCTGGGGGGGCCGGCTCTGCGACAAAGATGTCAACGAATGC
AGCCAGGAGAACGGGGGCTGCCTCCAGATCTGCCACAACAAGCCGGGTAGCTTCCACTGT
TCCTGCCACAGCGGCTTCGAGCTCTCCTCTGATGGCAGGACCTGCCAAGACATAGACGAG
TGCGCAGACTCGGAGGCCTGCGGGGAGGCGCGCTGCAAGAACCTGCCCGGCTCCTACTCC
TGCCTCTGTGACGAGGGCTTTGCGTACAGCTCCCAGGAGAAGGCTTGCCGAGATGTGGAC
GAGTGTCTGCAGGGCCGCTGTGAGCAGGTCTGCGTGAACTCCCCAGGGAGCTACACCTGC
CACTGTGACGGGCGTGGGGGCCTCAAGCTGTCCCAGGACATGGACACCTGTGAGGACATC
TTGCCGTGCGTGCCCTTCAGCGTGGCCAAGAGTGTGAAGTCCTTGTACCTGGGCCGGATG
TTCAGTGGGACCCCCGTGATCCGACTGCGCTTCAAGAGGCTGCAGCCCACCAGGCTGGTA
GCTGAGTTTGACTTCCGGACCTTTGACCCCGAGGGCATCCTCCTCTTTGCCGGAGGCCAC
CAGGACAGCACCTGGATCGTGCTGGCCCTGAGAGCCGGCCGGCTGGAGCTGCAGCTGCGC
TACAACGGTGTCGGCCGTGTCACCAGCAGCGGCCCGGTCATCAACCATGGCATGTGGCAG
ACAATCTCTGTTGAGGAGCTGGCGCGGAATCTGGTCATCAAGGTCAACAGGGATGCTGTC
ATGAAAATCGCGGTGGCCGGGGACTTGTTCCAACCGGAGCGAGGACTGTATCATCTGAAC
CTGACCGTGGGAGGTATTCCCTTCCATGAGAAGGACCTCGTGCAGCCTATAAACCCTCGT
CTGGATGGCTGCATGAGGAGCTGGAACTGGCTGAACGGAGAAGACACCACCATCCAGGAA
ACGGTGAAAGTGAACACGAGGATGCAGTGCTTCTCGGTGACGGAGAGAGGCTCTTTCTAC
CCCGGGAGCGGCTTCGCCTTCTACAGCCTGGACTACATGCGGACCCCTCTGGACGTCGGG
ACTGAATCAACCTGGGAAGTAGAAGTCGTGGCTCACATCCGCCCAGCCGCAGACACAGGC
GTGCTGTTTGCGCTCTGGGCCCCCGACCTCCGTGCCGTGCCTCTCTCTGTGGCACTGGTA
GACTATCACTCCACGAAGAAACTCAAGAAGCAGCTGGTGGTCCTGGCCGTGGAGCATACG
GCCTTGGCCCTAATGGAGATCAAGGTCTGCGACGGCCAAGAGCACGTGGTCACCGTCTCG
CTGAGGGACGGTGAGGCCACCCTGGAGGTGGACGGCACCAGGGGCCAGAGCGAGGTGAGC
GCCGCGCAGCTGCAGGAGAGGCTGGCCGTGCTCGAGAGGCACCTGCGGAGCCCCGTGCTC
ACCTTTGCTGGCGGCCTGCCAGATGTGCCGGTGACTTCAGCGCCAGTCACCGCGTTCTAC
CGCGGCTGCATGACACTGGAGGTCAACCGGAGGCTGCTGGACCTGGACGAGGCGGCGTAC
AAGCACAGCGACATCACGGCCCACTCCTGCCCCCCCGTGGAGCCCGCCGCAGCCTAG

Clone variation with respect to NM_000820.2
>OriGene 5' read for NM_000820 unedited
GCAATTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGCCGCCAGNA
CGGGATGACCGGAGCCTCCGCCCCGCGGCGCCCGCGGCTCGCCTCGGCCTCCCGGGCGCT
CTGACCGCGCGTCCCCGGCCCGCCATGGCCCCTTCGCTCTCGCCCGGGCCCGCCGCCCTG
CGCCGCGCGCCGCAGCTGCTGCTGCTGCTGCTGGCCGCGGAGTGCGCGCTTGCCGCGCTG
TTGCCGGCGCGCGAGGCCACGCAGTTCCTGCGGCCCAGGCAGCGCCGCGCCTTTCAGGTC
TTCGAGGAGGCCAAGCAGGGCCACCTGGAGAGGGAGTGCGTGGAGGAGCTGTGCAGCCGC
GAGGAGGCGCGGGAGGTGTTCGAGAACGACCCCGAGACGGATTATTTTTACCCAAGATAC
TTAGACTGCATCAACAAGTATGGGTCTCCGTACACCAAAAACTCAGGCTTCGCCACCTGC
GTGCAAAACCTGCCTGACCAGTGCACGCCCAACCCCTGCGATAGGAAGGGGACCCAAGCC
TGCCAGGACCTCATGGGCAACTTCTTCTGCCTGTGTAAAGCTGGCTGGGGGGGCCGGCTC
TGCGACAAAGATGTCAACGAATGCAGCCAGGAGAACGGNGGCTGCCTCCAGATCTGCCAC
AACAAGCCGGGTAGCTTCCACTGTTCCTGCCACAGCGGCTTCGAGCTCTCCTCTGATGGC
AGGACCTGCCAAGACATANACGAGTGCGCAGAANNTCGAGCCTGNCGGGGAGGCGCGCTG
CAAGAACCTGCCCGGGGCTCTACTCTGCCTCTGGGACGAAGGGCTNTGCGTACAGCTCCC
AAGANAAGGCTGCCCGAATGTGGAACAATGTCCTGCAGGGCCCTGGGAAACCAGTTCTGC
GTGAACTCCCCAGNAGCTACACTGCCTTGGACCGGGGGGGTGGGGGGGGCTTCAAGCTGT
CCCAGAACTGACCCCTCTGTGAGGGTACTGNGCCCGGGCTGCCCTCN
>OriGene 3' read for NM_000820 unedited
NNNTTTGCTCTGGACCGGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTAACAAACCTTTTGGAAAATATTTTATTT
TCCATATTTAAAAGCCAAAAAAAAGCGCTGGGTAATAAAAATAATAGAAAATTTTTTTTT
TCAACCCCGTTTTGGGCTGGGCCGGCCTCCCCGGGCCCGGGCCCACGGTTGAGGGCGCGG
GGTAAAAGGCCCCAAGCCCATTTCACTTTTTACAGATTTGTTACAGGCCGGGAGGGTCAC
AAAGGAAAGCCCAGTTTTAAACAGGGCCCCACGGGGGAGGAGGGAGCCCCCAGGCTCCTC
CCGGTTGTTTGGGACAAAAACTGAAAACCCTGCCGGGTCCCGGGGGGGCCTAGGCTGGGG
GGGGCTCCACGGGGGGGCAGGAGGGGGCCGTGATGTCCTTGTGCTTGTACCCCGCCTTGT
CCAGGTCCAGAAGCCTCCGGTTGACCTCCAGGGTCATGCACCCGCGGAAAAACGCGGGGA
CTGGCGCTAAAGTCACCGGCACATTTGGCAGGCCGCCAACAAAGGGGAGCACGGGGCTCC
GAAGGGGCCTTTAGAGCACGGCCAGCCTTTCCTGGAGTTGGGGGGGGCTCACCTCGTTTT
GGCCCCTGGGGGCCGTCCCCTCCCAGGGGGGCCTCACCGTCCCTCAGGGAGAACGGGGAC
CACGTGCTCTTTGGCCGGGCGCAAACCTTTGATCTTCCATTAGGGGCAAAGGCCGTATTG
CTCCACGGCCAAGGACCACCAGCGTGTTTTTTGAAGTTCTTTCGGGGGAGAGAAAGCCAA
CCCGGGCCCAAAAAAAAGGCCGCCCCGGAGGTCGGGGGGCCCAAAGCGAAAAAACCCCCC
TGGTTTGGGGTTGGGCGATGGTACACCCCACTCCCCCTCCCAG
Restriction Sites NotI-NotI     
ACCN NM_000820
Insert Size 2550 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_000820.1, NP_000811.1
RefSeq Size 2461 bp
RefSeq ORF 2037 bp
Locus ID 2621
Cytogenetics 13q34
Domains GLA, LamG, EGF_CA, EGF, EGF
Protein Families Druggable Genome, Secreted Protein
Gene Summary 'This gene encodes a gamma-carboxyglutamic acid (Gla)-containing protein thought to be involved in the stimulation of cell proliferation. This gene is frequently overexpressed in many cancers and has been implicated as an adverse prognostic marker. Elevated protein levels are additionally associated with a variety of disease states, including venous thromboembolic disease, systemic lupus erythematosus, chronic renal failure, and preeclampsia. [provided by RefSeq, Aug 2014]'

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