Dopamine Receptor D1 (DRD1) (NM_000794) Human Untagged Clone

CAT#: SC119692

DRD1 (untagged)-Human dopamine receptor D1 (DRD1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DRD1
• Synonyms: DADR; DRD1A
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC119692 sequence for NM_000794 edited (data generated by NextGen Sequencing)
  ATGAGGACTCTGAACACCTCTGCCATGGACGGGACTGGGCTGGTGGTGGAGAGGGACTTC
  TCTGTTCGTATCCTCACTGCCTGTTTCCTGTCGCTGCTCATCCTGTCCACGCTCCTGGGG
  AACACGCTGGTCTGTGCTGCCGTTATCAGGTTCCGACACCTGCGGTCCAAGGTGACCAAC
  TTCTTTGTCATCTCCTTGGCTGTGTCAGATCTCTTGGTGGCCGTCCTGGTCATGCCCTGG
  AAGGCAGTGGCTGAGATTGCTGGCTTCTGGCCCTTTGGGTCCTTCTGTAACATCTGGGTG
  GCCTTTGACATCATGTGCTCCACTGCATCCATCCTCAACCTCTGTGTGATCAGCGTGGAC
  AGGTATTGGGCTATCTCCAGCCCTTTCCGGTATGAGAGAAAGATGACCCCCAAGGCAGCC
  TTCATCCTGATCAGTGTGGCATGGACCTTGTCTGTACTCATCTCCTTCATCCCAGTGCAG
  CTCAGCTGGCACAAGGCAAAACCCACAAGCCCCTCTGATGGAAATGCCACTTCCCTGGCT
  GAGACCATAGACAACTGTGACTCCAGCCTCAGCAGGACATATGCCATCTCATCCTCTGTA
  ATAAGCTTTTACATCCCTGTGGCCATCATGATTGTCACCTACACCAGGATCTACAGGATT
  GCTCAGAAACAAATACGGCGCATTGCGGCCTTGGAGAGGGCAGCAGTCCACGCCAAGAAT
  TGCCAGACCACCACAGGTAATGGAAAGCCTGTCGAATGTTCTCAACCGGAAAGTTCTTTT
  AAGATGTCCTTCAAAAGAGAAACTAAAGTCCTGAAGACTCTGTCGGTGATCATGGGTGTG
  TTTGTGTGCTGTTGGCTACCTTTCTTCATCTTGAACTGCATTTTGCCCTTCTGTGGGTCT
  GGGGAGACGCAGCCCTTCTGCATTGATTCCAACACCTTTGACGTGTTTGTGTGGTTTGGG
  TGGGCTAATTCATCCTTGAACCCCATCATTTATGCCTTTAATGCTGATTTTCGGAAGGCA
  TTTTCAACCCTCTTAGGATGCTACAGACTTTGCCCTGCGACGAATAATGCCATAGAGACG
  GTGAGTATCAATAACAATGGGGCCGCGATGTTTTCCAGCCATCATGAGCCACGAGGCTCC
  ATCTCCAAGGAGTGCAATCTGGTTTACCTGATCCCACATGCTGTGGGCTCCTCTGAGGAC
  CTGAAAAAGGAGGAGGCAGCTGGCATCGCCAGACCCTTGGAGAAGCTGTCCCCAGCCCTA
  TCGGTCATATTGGACTATGACACTGACGTCTCTCTGGAGAAGATCCAACCCATCACACAA
  AACGGTCAGCACCCAACCTGA
  
  Clone variation with respect to NM_000794.3
  1263 a=>g
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000794 unedited
  GCGGCCGCGAATTCGGCACGAGNAGCGGGCAGTGCCTGCGGGGAGGCGCGGGGCCCTGCT
  CTGTAGGGCTGAAGGCCGCCCGAGGTTCGCCAAGGCTCTGGGCTCTCGAAAGGAAGCCAA
  GAAAAGAAGCTGCCCAGGTGACCAGTCCTGGGAGTGCTCTCTCCCAAGGAAGCTCCGAGC
  GCCCAGGAGCCCTTAGCCGGGGTCTAGTGCCCTTTGAACAATCTCCAGCTCTTCAAGGAA
  GTGGGCCGCCGCCGCCTCTCTTGGGACCTGGCCTGAGATCCTTTCCCCAAACGCACCCCG
  GCGATTTTTGCGCACCGGGAGCCGAACCCCTGCTGCGCGCAGCTGGCTGGGCTCANGCGC
  GCTTCCTCAACGTTTCGAGCCGCTGCCCCAGCGAAGTCACATTTCAGCTCAGCGGCTTTG
  GCTATGAGAGACACGACCCCAAGGCAGGGCCGTTGGAAAGCTGCTGAAGACCCAGGGGCT
  TGAAAGAACAAAAAAACCTGTTTTTTCAACTGGATTTAAAAAGGGAAAAATCTCCTGTCC
  CCCCCAAAAAAGCCCCGCCCCCAAATGGGTTGGCACTGGCTTACAAAACAGGCCCCCGAG
  GGCCCGGGTTGGGGGATTTAAAAATTGCCAAAAAACCCCGGCTTTTTTGGGGGGAATTAA
  GGGTTTTTTGGGGGCCCCAAAAAGGCCCCTTCCCGGGGGGGGCCAAAAACCACCTGTTAA
  AAAAAAAAGGGCCCCCCCCCCGGTTGGTTTGGTGGTTGGCCTTAGGGGGGCTCTTTTTGG
  GATGAGGGGAGGGCGCCCCCCCGCGAGGAAAAAAAATTTTTTGTATAAAAAATTCTCCTG
  GGGGGGGGGCGCCCCCAAAAAAAACCCGCCCCCCCCTTCCTCTTCCTTAATAAAGAGGGG
  GGGGGGCCACCCACTCCGTTCTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000794 unedited
  CCCCCATTCTGGCTCTCAATGTTCAGTTCATTGCTTATCAACAGGATACGTTGTAAACAT
  TTCAAAGAACTCTGTTGAAAGCCCCCGAGTTGGCATCTGGCAAGGGAGGCTTATGATACT
  TTTTACAGTCCGGGTGATGATGCAGGAACCTGATTCCAAAGCACAGCAGAAAGGACTAGC
  ATTTGTCAAAAGAGATGCTGATGGCTTTGGGGGAGCTCAACACACCCAAAGGGAAGGATT
  CTTCTGTTTCTCCCATCAACAGAAGTATCTGACTCAAGAATGATAATGAGGCACTATTCG
  TTAGTTAGTATACCATTAACATTTAAAGACTCCTTTAAAAATCAGCTCTAAATTCAGATT
  AAAGCACTATAAAAAGTAGCCCCACTGACTGGTTTGGTTTGACCTGGTAAGATGGAAATG
  CAGGGTTTGAGTTTGGTCCCTCAGTGGGGCTGCTGTAACCCACTGTCTGTGCTACAGATC
  TCTCTCCAGGAAAGCCATTTGTGTGGTTCAGAAAAACTACCTGACACATGAAATGAGAAA
  AGATGGAGAGGGCCAATTATTTTACATAAATACAAAGCAGCATATACTTTTCATTACCAC
  CTAAGATCGTAAATTTAATGCTGGGCTCTTCTTAAGTTGGCTTTTATTTAAGATATTTAC
  AGAACTGCTAATTCCCCTGGGAAAGTCATTTGTCATTTAAAACGTTTTGAACACAGTAGT
  AGCTATACTTTTTTAAATATTTCAAAAACTTTTCAGAAAAAGAAAGCATTTATAGCATTT
  GTCAATTCTCACCTTGCATTTATCTGTGTCCATGAATTTTAGGCATCATTTCAACTTTAT
  TCCTTTATTTATCAGTTTCTGCTGTGTTTTTCAGAGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_000794
• Insert Size: 3800 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000794.2, NP_000785.1
• RefSeq Size: 2776 bp
• RefSeq ORF: 1341 bp
• Locus ID: 1812
• Cytogenetics: 5q35.2
• Domains: 7tm_1
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Calcium signaling pathway, Gap junction, Neuroactive ligand-receptor interaction
• Gene Summary: 'This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq, Jul 2008]'