CD62L (SELL) (NM_000655) Human Untagged Clone

CAT#: SC119745

SELL (untagged)-Human selectin L (SELL), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SELL
• Synonyms: CD62L; LAM1; LECAM1; LEU8; LNHR; LSEL; LYAM1; PLNHR; TQ1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC119745 sequence for NM_000655 edited (data generated by NextGen Sequencing)
  ATGGGCTGCAGAAGAACTAGAGAAGGACCAAGCAAAGCCATGATATTTCCATGGAAATGT
  CAGAGCACCCAGAGGGACTTATGGAACATCTTCAAGTTGTGGGGGTGGACAATGCTCTGT
  TGTGATTTCCTGGCACATCATGGAACCGACTGCTGGACTTACCATTATTCTGAAAAACCC
  ATGAACTGGCAAAGGGCTAGAAGATTCTGCCGAGACAATTACACAGATTTAGTTGCCATA
  CAAAACAAGGCGGAAATTGAGTATCTGGAGAAGACTCTGCCTTTCAGTCGTTCTTACTAC
  TGGATAGGAATCCGGAAGATAGGAGGAATATGGACGTGGGTGGGAACCAACAAATCTCTT
  ACTGAAGAAGCAGAGAACTGGGGAGATGGTGAGCCCAACAACAAGAAGAACAAGGAGGAC
  TGCGTGGAGATCTATATCAAGAGAAACAAAGATGCAGGCAAATGGAACGATGACGCCTGC
  CACAAACTAAAGGCAGCCCTCTGTTACACAGCTTCTTGCCAGCCCTGGTCATGCAGTGGC
  CATGGAGAATGTGTAGAAATCATCAATAATTACACCTGCAACTGTGATGTGGGGTACTAT
  GGGCCCCAGTGTCAGTTTGTGATTCAGTGTGAGCCTTTGGAGGCCCCAGAGCTGGGTACC
  ATGGACTGTACTCACCCTTTGGGAAACTTCAGCTTCAGCTCACAGTGTGCCTTCAGCTGC
  TCTGAAGGAACAAACTTAACTGGGATTGAAGAAACCACCTGTGGACCATTTGGAAACTGG
  TCATCTCCAGAACCAACCTGTCAAGTGATTCAGTGTGAGCCTCTATCAGCACCAGATTTG
  GGGATCATGAACTGTAGCCATCCCCTGGCCAGCTTCAGCTTTACCTCTGCATGTACCTTC
  ATCTGCTCAGAAGGAACTGAGTTAATTGGGAAGAAGAAAACCATTTGTGAATCATCTGGA
  ATCTGGTCAAATCCTAGTCCAATATGTCAAAAATTGGACAAAAGTTTCTCAATGATTAAG
  GAGGGTGATTATAACCCCCTCTTCATTCCAGTGGCAGTCATGGTTACTGCATTCTCTGGG
  TTGGCATTTATCATTTGGCTGGCAAGGAGATTAAAAAAAGGCAAGAAATCCAAGAGAAGT
  ATGAATGACCCATATTAA
  
  Clone variation with respect to NM_000655.4
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000655 unedited
  NCCCGTTCAGAATTGTATACGACTCATATAGGCGGCCGCGNAATTCGCACGAGGCAGCAC
  AGCACACTCCCTTTGGGCAAGGACCTGAGACCCTTGTGCTAAGTCAAGAGGCTCAATGGG
  CTGCAGAAGAACTAGAGAAGGACCAAGCAAAGCCATGATATTTCCATGGAAATGTCAGAG
  CACCCAGAGGGACTTATGGAACATCTTCAAGTTGTGGGGGTGGACAATGCTCTGTTGTGA
  TTTCCTGGCACATCATGGAACCGACTGCTGGACTTACCATTATTCTGAAAAACCCATGAA
  CTGGCAAAGGGCTAGAAGATTCTGCCGAGACAATTACACAGATTTAGTTGCCATACAAAA
  CAAGGCGGAAATTGAGTATCTGGAGAAGACTCTGCCTTTCAGTCGTTCTTACTACTGGAT
  AGGAATCCGGAAGATAGGAGGAATATGGACGTGGGTGGGAACCAACAAATCTCTTACTGA
  AGAAGCAGAGAACTGGGGAGATGGTGAGCCCAACAACAAGAAGAACAAGGAGGACTGCGT
  GGAGATCTATATCAAGAGAAACAAAGATGCAGGCAAATGGAACGATGACGCCTGCCACAA
  ACTAAAGGCAGCCCTCTGTTACACAGCTTCTTGCCAGCCCTGGTCATGCAGTGGCCATGG
  AGAATGTGTAGAAATCATCAATAATTACACCTGCAACTGTGATGTGGGGTACTATGGGCC
  CCAGTGTCAGTTTGTGATTCAGTGTGAGCCTTTGGAGGCCCCAGAGCTGGGTACCATGGA
  CTGTACTCACCCTTTNGGGAACTTCAGCTTCAGCTCACAGTGTGCCTTCAGCTGCTCTGA
  AGGAACAACTTACTGGGATTGAAGAAACCACTGTGGACATTGGNAACTGGTCATCTNCAG
  AACCACTGTCAGTC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000655 unedited
  CGCGGCCGCATCTANATCGAGTTTTTTTTTTTTTTTTTTAACACTTAAAAAGCAGGCTTT
  ATTCAAATGCAAAATTGCATGTTACAGGGTAACCTTTCAGTAAGAAGCCAGGAAGAGGAG
  CTCATCATGGGTTGGATTAGTAAAGGACTAGTTATAAAAGAAGTGGTGGGGTTGAGGGAG
  GCCTGAGATGAAATTTAAAGAATATGTAGAATCTAGGTAAGTGGATAAAAGGTCTGGGGG
  CAGGGGAAAGGAGAGCATTTCATTGTGAATCAAGGAATTTCTCCACCTGTTTTAACTCTT
  CCATATGACATCAAAGAGATGTCACTTGCAGCTAGCATTTCAGTGATGTTTTCTTACTAA
  TAATATCGTGATAAAAGAAACATTGACTATAAGAAATAGGAATGGGTCTCATAAAAGGAA
  ACAGCAAAACCCCCAAACTAAAAAACAGCGCAGGCTATTTCTCTCTTCTCTCCTTTTGCT
  TGGCACTCATGAGATGCTAGGTGTGGAAGTCACCCAACTGAAAAAGAGAGGTGGCTGAAC
  AAAGTGGGGAGGCTTAACCCACTTAAATAGGATGGGCCAATTCACAGACGGCGAGGTCTA
  CAGCGCAAATACGACCTCTTTACCTTGACCATGACCCCATTTCTTTCCTGGAGTTTAAAA
  AAAGGGTACCCGACACTTCTTGACCTTCTATATTAACGTCCCTTCCCAGCTTCCGAAAAC
  CTCGTTCATTCGCTTTTTCCCCACACCTCCTCCCCACTCCCATTAGGACCCTATATTTTA
  CTTCTCTTATACCACCCCTGCCACCAGTTTCCCCCCTTAGAATTGCCCTCTATACCTTTT
  TTATAAATACCCAACATATATTCTTTTATTTAATGTATAATTGTCTACCTCCCCCCGCAC
  TTTATTAATCCCTACCATCCCTCCGCCCTGCATTTTTATGTATN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_000655
• Insert Size: 2450 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000655.2, NP_000646.1
• RefSeq Size: 2324 bp
• RefSeq ORF: 1119 bp
• Locus ID: 6402
• Cytogenetics: 1q24.2
• Domains: CCP, CLECT, EGF, EGF
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs)
• Gene Summary: 'This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]'
  Transcript Variant: This variant (1) represents the longer transcript and encodes the functional protein. CCDS Note: The coding region has been scaled back at the 5' end to begin from a start codon that is better supported by conservation data.