CD62L (SELL) (NM_000655) Human Untagged Clone

CAT#: SC119745

SELL (untagged)-Human selectin L (SELL), transcript variant 1


  "NM_000655" in other vectors (6)

Reconstitution Protocol

USD 660.00

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol SELL
Synonyms CD62L; LAM1; LECAM1; LEU8; LNHR; LSEL; LYAM1; PLNHR; TQ1
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC119745 sequence for NM_000655 edited (data generated by NextGen Sequencing)
ATGGGCTGCAGAAGAACTAGAGAAGGACCAAGCAAAGCCATGATATTTCCATGGAAATGT
CAGAGCACCCAGAGGGACTTATGGAACATCTTCAAGTTGTGGGGGTGGACAATGCTCTGT
TGTGATTTCCTGGCACATCATGGAACCGACTGCTGGACTTACCATTATTCTGAAAAACCC
ATGAACTGGCAAAGGGCTAGAAGATTCTGCCGAGACAATTACACAGATTTAGTTGCCATA
CAAAACAAGGCGGAAATTGAGTATCTGGAGAAGACTCTGCCTTTCAGTCGTTCTTACTAC
TGGATAGGAATCCGGAAGATAGGAGGAATATGGACGTGGGTGGGAACCAACAAATCTCTT
ACTGAAGAAGCAGAGAACTGGGGAGATGGTGAGCCCAACAACAAGAAGAACAAGGAGGAC
TGCGTGGAGATCTATATCAAGAGAAACAAAGATGCAGGCAAATGGAACGATGACGCCTGC
CACAAACTAAAGGCAGCCCTCTGTTACACAGCTTCTTGCCAGCCCTGGTCATGCAGTGGC
CATGGAGAATGTGTAGAAATCATCAATAATTACACCTGCAACTGTGATGTGGGGTACTAT
GGGCCCCAGTGTCAGTTTGTGATTCAGTGTGAGCCTTTGGAGGCCCCAGAGCTGGGTACC
ATGGACTGTACTCACCCTTTGGGAAACTTCAGCTTCAGCTCACAGTGTGCCTTCAGCTGC
TCTGAAGGAACAAACTTAACTGGGATTGAAGAAACCACCTGTGGACCATTTGGAAACTGG
TCATCTCCAGAACCAACCTGTCAAGTGATTCAGTGTGAGCCTCTATCAGCACCAGATTTG
GGGATCATGAACTGTAGCCATCCCCTGGCCAGCTTCAGCTTTACCTCTGCATGTACCTTC
ATCTGCTCAGAAGGAACTGAGTTAATTGGGAAGAAGAAAACCATTTGTGAATCATCTGGA
ATCTGGTCAAATCCTAGTCCAATATGTCAAAAATTGGACAAAAGTTTCTCAATGATTAAG
GAGGGTGATTATAACCCCCTCTTCATTCCAGTGGCAGTCATGGTTACTGCATTCTCTGGG
TTGGCATTTATCATTTGGCTGGCAAGGAGATTAAAAAAAGGCAAGAAATCCAAGAGAAGT
ATGAATGACCCATATTAA

Clone variation with respect to NM_000655.4
>OriGene 5' read for NM_000655 unedited
NCCCGTTCAGAATTGTATACGACTCATATAGGCGGCCGCGNAATTCGCACGAGGCAGCAC
AGCACACTCCCTTTGGGCAAGGACCTGAGACCCTTGTGCTAAGTCAAGAGGCTCAATGGG
CTGCAGAAGAACTAGAGAAGGACCAAGCAAAGCCATGATATTTCCATGGAAATGTCAGAG
CACCCAGAGGGACTTATGGAACATCTTCAAGTTGTGGGGGTGGACAATGCTCTGTTGTGA
TTTCCTGGCACATCATGGAACCGACTGCTGGACTTACCATTATTCTGAAAAACCCATGAA
CTGGCAAAGGGCTAGAAGATTCTGCCGAGACAATTACACAGATTTAGTTGCCATACAAAA
CAAGGCGGAAATTGAGTATCTGGAGAAGACTCTGCCTTTCAGTCGTTCTTACTACTGGAT
AGGAATCCGGAAGATAGGAGGAATATGGACGTGGGTGGGAACCAACAAATCTCTTACTGA
AGAAGCAGAGAACTGGGGAGATGGTGAGCCCAACAACAAGAAGAACAAGGAGGACTGCGT
GGAGATCTATATCAAGAGAAACAAAGATGCAGGCAAATGGAACGATGACGCCTGCCACAA
ACTAAAGGCAGCCCTCTGTTACACAGCTTCTTGCCAGCCCTGGTCATGCAGTGGCCATGG
AGAATGTGTAGAAATCATCAATAATTACACCTGCAACTGTGATGTGGGGTACTATGGGCC
CCAGTGTCAGTTTGTGATTCAGTGTGAGCCTTTGGAGGCCCCAGAGCTGGGTACCATGGA
CTGTACTCACCCTTTNGGGAACTTCAGCTTCAGCTCACAGTGTGCCTTCAGCTGCTCTGA
AGGAACAACTTACTGGGATTGAAGAAACCACTGTGGACATTGGNAACTGGTCATCTNCAG
AACCACTGTCAGTC
>OriGene 3' read for NM_000655 unedited
CGCGGCCGCATCTANATCGAGTTTTTTTTTTTTTTTTTTAACACTTAAAAAGCAGGCTTT
ATTCAAATGCAAAATTGCATGTTACAGGGTAACCTTTCAGTAAGAAGCCAGGAAGAGGAG
CTCATCATGGGTTGGATTAGTAAAGGACTAGTTATAAAAGAAGTGGTGGGGTTGAGGGAG
GCCTGAGATGAAATTTAAAGAATATGTAGAATCTAGGTAAGTGGATAAAAGGTCTGGGGG
CAGGGGAAAGGAGAGCATTTCATTGTGAATCAAGGAATTTCTCCACCTGTTTTAACTCTT
CCATATGACATCAAAGAGATGTCACTTGCAGCTAGCATTTCAGTGATGTTTTCTTACTAA
TAATATCGTGATAAAAGAAACATTGACTATAAGAAATAGGAATGGGTCTCATAAAAGGAA
ACAGCAAAACCCCCAAACTAAAAAACAGCGCAGGCTATTTCTCTCTTCTCTCCTTTTGCT
TGGCACTCATGAGATGCTAGGTGTGGAAGTCACCCAACTGAAAAAGAGAGGTGGCTGAAC
AAAGTGGGGAGGCTTAACCCACTTAAATAGGATGGGCCAATTCACAGACGGCGAGGTCTA
CAGCGCAAATACGACCTCTTTACCTTGACCATGACCCCATTTCTTTCCTGGAGTTTAAAA
AAAGGGTACCCGACACTTCTTGACCTTCTATATTAACGTCCCTTCCCAGCTTCCGAAAAC
CTCGTTCATTCGCTTTTTCCCCACACCTCCTCCCCACTCCCATTAGGACCCTATATTTTA
CTTCTCTTATACCACCCCTGCCACCAGTTTCCCCCCTTAGAATTGCCCTCTATACCTTTT
TTATAAATACCCAACATATATTCTTTTATTTAATGTATAATTGTCTACCTCCCCCCGCAC
TTTATTAATCCCTACCATCCCTCCGCCCTGCATTTTTATGTATN
Restriction Sites NotI-NotI     
ACCN NM_000655
Insert Size 2450 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_000655.2, NP_000646.1
RefSeq Size 2324 bp
RefSeq ORF 1119 bp
Locus ID 6402
Cytogenetics 1q24.2
Domains CCP, CLECT, EGF, EGF
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs)
Gene Summary 'This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]'
Transcript Variant: This variant (1) represents the longer transcript and encodes the functional protein. CCDS Note: The coding region has been scaled back at the 5' end to begin from a start codon that is better supported by conservation data.

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