IGFBP3 (NM_000598) Human Untagged Clone
CAT#: SC119779
IGFBP3 (untagged)-Human insulin-like growth factor binding protein 3 (IGFBP3), transcript variant 2
"NM_000598" in other vectors (6)
Product Images
![](https://cdn.origene.com/img/defaults-img-expression-plasmids.jpg)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Symbol | IGFBP3 |
Synonyms | BP-53; IBP3 |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene sequence for NM_000598 edited
GAATTCGGCACGAGGTGGGCGCTGAGGATCAGCCGCTTCCTGCCTGGATTCCACAGCTTC GCGCCGTGTACTGTCGCCCCATCCCTGCGCGCCCAGCCTGCCAAGCAGCGTGCCCCGGTT GCAGGCGTCATGCAGCGGGCGCGACCCACGCTCTGGGCCGCTGCGCTGACTCTGCTGGTG CTGCTCCGCGGGCCGCCGGTGGCGCGGGCTGGCGCGAGCTCGGGGGGCTTGGGTCCCGTG GTGCGCTGCGAGCCGTGCGACGCGCGTGCACTGGCCCAGTGCGCGCCTCCGCCCGCCGTG TGCGCGGAGCTGGTGCGCGAGCCGGGCTGCGGCTGCTGCCTGACGTGCGCACTGAGCGAG GGCCAGCCGTGCGGCATCTACACCGAGCGCTGTGGCTCCGGCCTTCGCTGCCAGCCGTCG CCCGACGAGGCGCGACCGCTGCAGGCGCTGCTGGACGGCCGCGGGCTCTGCGTCAACGCT AGTGCCGTCAGCCGCCTGCGCGCCTACCTGCTGCCAGCGCCGCCAGCTCCAGGAAATGCT AGTGAGTCGGAGGAAGACCGCAGCGCCGGCAGTGTGGAGAGCCCGTCCGTCTCCAGCACG CACCGGGTGTCTGATCCCAAGTTCCACCCCCTCCATTCAAAGATAATCATCATCAAGAAA GGGCATGCTAAAGACAGCCAGCGCTACAAAGTTGACTACGAGTCTCAGAGCACAGATACC CAGAACTTCTCCTCCGAGTCCAAGCGGGAGACAGAATATGGTCCCTGCCGTAGAGAAATG GAAGACACACTGAATCACCTGAAGTTCCTCAATGTGCTGAGTCCCAGGGGTGTACACATT CCCAACTGTGACAAGAAGGGATTTTATAAGAAAAAGCAGTGTCGCCCTTCCAAAGGCAGG AAGCGGGGCTTCTGCTGGTGTGTGGATAAGTATGGGCAGCCTCTCCCAGGCTACACCACC AAGGGGAAGGAGGACGTGCACTGCTACAGCATGCAGAGCAAGTAGACGCCTGCCGCAAGG TTAATGTGGAGCTCAAATATGCCTTATTTTGCACAAAAGACTGCCAAGGACATGACCAGC AGCTGGCTACAGCCTCGATTTATATTTCTGTTTGTGGTGAACTGATTTTTTTTAAACCAA AGTTTAGAAAGAGGTTTTTGAAATGCCTATGGTTTCTTTGAATGGTAAACTTGAGCATCT TTTCACTTTCCAGTAGTCAGCAAAGAGCAGTTTGAATTTTCTTGTCGCTTCCTATCAAAA TATTCAGAGACTCGAGCACAGCACCCAGACTTCATGCGCCCGTGGAATGCTCACCACATG TTGGTCGAAGCGGCCGACCACTGACTTTGTGACTTAGGCGGCTGTGTTGCCTATGTAGAG AACACGCTTCACCCCCACTCCCCGTACAGTGCGCACAGGCTTTATCGAGAATAGGAAAAC CTTTAAACCCCGGTCATCCGGACATCCCAACGCATGCTCCTGGAGCTCACAGCCTTCTGT GGTGTCATTTCTGAAACAAGGGCGTGGATCCCTCAACCAAGAAGAATGTTTATGTCTTCA AGTGACCTGTACTGCTTGGGGACTATTGGAGAAAATAAGGTGGAGTCCTACTTGTTTAAA AAATATGTATCTAAGAATGTTCTAGGGCACTCTGGGAACCTATAAAGGCAGGTATTTCGG GCCCTCCTCTTCAGGAATCTTCCTGAAGACATGGCCCAGTCGAAGGCCCAGGATGGCTTT TGCTGCGGCCCCGTGGGGTAGGAGGGACAGAGAGACAGGGAGAGTCAGCCTCCACATTCA GAGGCATCACAAGTAATGGCACAATTCTTCGGATGACTGCAGAAAATAGTGTTTTGTAGT TCAACAACTCAAGACGAAGCTTATTTCTGAGGATAAGCTCTTTAAAGGCAAAGCTTTATT TTCATCTCTCATCTTTTGTCCTCCTTAGCACAATGTAAAAAAGAATAGTAATATCAGAAC AGGAAGGAGGAATGGCTTGCTGGGGAGCCCATCCAGGACACTGGGAGCACATAGAGATTC ACCCATGTTTGTTGAACTTAGAGTCATTCTCATGCTTTTCTTTATAATTCACACATATAT GCAGAGAAGATATGTTCTTGTTAACATTGTATACAACATAGCCCCAAATATAGTAAGATC TATACTAGATAATCCTAGATGAAATGTTAGAGATGCTATATGATACAACTGTGGCCATGA CTGAGGAAAGGAGCTCACGCCCAGAGACTGGGCTGCTCTCCCGGAGGCCAAACCCAAGAA GGTCTGGCAAAGTCAGGCTCAGGGAGACTCTGCCCTGCTGCAGACCTCGGTGTGGACACA CGCTGCATAGAGCTCTCCTTGAAAACAGAGGGGTCTCAAGACATTCTGCCTACCTATTAG CTTTTCTTTATTTTTTTAACTTTTTGGGGGGAAAAGTATTTTTGAGAAGTTTGTCTTGCA ATGTATTTATAAATAGTAAATAAAGTTTTTACCATTAAAAAAAAAAAAAAAAAACTCGAC >OriGene 5' read for NM_000598 unedited
TTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGTGGGCGCTGAGGATC AGCCGCTTCCTGCCTGGATTCCACAGCTTCGCGCCGTGTACTGTCGCCCCATCCCTGCGC GCCCAGCCTGCCAAGCAGCGTGCCCCGGTTGCAGGCGTCATGCAGCGGGCGCGACCCACG CTCTGGGCCGCTGCGCTGACTCTGCTGGTGCTGCTCCGCGGGCCGCCGGTGGCGCGGGCT GGCGCGAGCTCGGGGGGCTTGGGTCCCGTGGTGCGCTGCGAGCCGTGCGACGCGCGTGCA CTGGCCCAGTGCGCGCCTCCGCCCGCCGTGTGCGCGGAGCTGGTGCGCGAGCCGGGCTGC GGCTGCTGCCTGACGTGCGCACTGAGCGAGGGCCAGCCGTGCGGCATCTACACCGAGCGC TGTGGCTCCGGCCTTCGCTGCCAGCCGTCGCCCGACGAGGCGCGACCGCTGCAGGCGCTG CTGGACGGCCGCGGGCTCTGCGTCAACGCTAGTGCCGTCAGCCGCCTGCGCGCCTACCTG CTGCCAGCGCCGCCAGCTCCAGGAAATGCTAGTGAGTCGGAGGAAGACCGCAGCGNCCGG CAGTGTGGAGAGCCCGTCCGTCTCCAGCACGCACCGGNGTGTCTGATCCCCAGTTCCACC CCCTCCATTCAAAGATAATCATCATCAAGAAAGGGCATGCTAAAGACAGCCAGCGCTACA AAGTTGACTACGAGTCTCAGAGCACAGATACCCAGAACTTNCTCTNCGAGTNCAGCGGGA GACGGAATATGGTCCCTGGCGTAGAAAAATGGAGAACACTGNATCACCTGAGTNCTCATG GGCTGATCCCCAGGGGTGACCATTCCCACTGGACANAAAGGGATTATAC >OriGene 3' read for NM_000598 unedited
CGCGGCCGCAATCTANAGTCGAGTTTTTTTTTTTTTTTTTTAATGGTAAAAACTTTATTT ACTATTTATAAATACATTGCAAGACAAACTTCTCAAAAATACTTTTCCCCCCAAAAAGTT AAAAAAATAAAGAAAAGCTAATAGGTAGGCAGAATGTCTTGAGACCCCTCTGTTTTCAAG GAGAGCTCTATGCAGCGTGTGTCCACACCGAGGTCTGCAGCAGGGCAGAGTCTCCCTGAA CCTGACTTTTGCCAGACCCCTTTTTGGGTTGGGCCTCCGGGGAAAACACCCCCATCTTTT GGGGGGGGACCCTCTTTTCCTTAATTTGGGGCCCACGTGGGTTTAATATAGCCCCTTTTA ACACTTCTCCCTCGGAATATTCTCCACTAAAACCCTTCTATTTTTTGGGGGGGTTTTTTG GGTTACCATGGGTTAAAAAAAAACCTTTTTTTTTGGTTATTTTTTTGGGGGGGTTTTATA AAAAAAAGTGTTGAAGTTTCTCTTTTTCACCACCCACGGGGGTTTCTCTTTTTCCCCCCC CGCGCGGGGGGGGGGCCCCACAAAAACCCCCTCTTCGTGGGGGGGAAAAATATTTTTTTT TTTCCTCGGCGGGGGGGGGCGCTTAAAAGAAAAAAAAAATCCGTCTCTCTGCTCTTACTC TCCCACCCAAAACCTTTTTGTTGGTGGGGGGAAACAACCACACAAATTCTTTTTTTTCCA AAACACGCAACACCCTCCCTCTCCCCTTTTCAACAGACCTGAGCTTTCTTTTCTTTTCTT TCCCCCCCCCCCCCCCGCCTCATACTTCAATACTCTCTTGCTGGCTCCTTCTTCTTTCTT CCGCCCCTTCCTCGTCTCTCCTT |
Restriction Sites | NotI-NotI |
ACCN | NM_000598 |
Insert Size | 2440 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones. |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_000598.4, NP_000589.2 |
RefSeq Size | 2620 bp |
RefSeq ORF | 876 bp |
Locus ID | 3486 |
Cytogenetics | 7p12.3 |
Domains | thyroglobulin_1, IB |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | p53 signaling pathway |
Gene Summary | 'This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]' Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1, resulting in a shorter protein (isoform b). |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC209150 | IGFBP3 (Myc-DDK-tagged)-Human insulin-like growth factor binding protein 3 (IGFBP3), transcript variant 2 |
USD 420.00 |
|
RG209150 | IGFBP3 (GFP-tagged) - Human insulin-like growth factor binding protein 3 (IGFBP3), transcript variant 2 |
USD 460.00 |
|
RC209150L1 | Lenti-ORF clone of IGFBP3 (Myc-DDK-tagged)-Human insulin-like growth factor binding protein 3 (IGFBP3), transcript variant 2 |
USD 768.00 |
|
RC209150L2 | Lenti-ORF clone of IGFBP3 (mGFP-tagged)-Human insulin-like growth factor binding protein 3 (IGFBP3), transcript variant 2 |
USD 620.00 |
|
RC209150L3 | Lenti-ORF clone of IGFBP3 (Myc-DDK-tagged)-Human insulin-like growth factor binding protein 3 (IGFBP3), transcript variant 2 |
USD 620.00 |
|
RC209150L4 | Lenti-ORF clone of IGFBP3 (mGFP-tagged)-Human insulin-like growth factor binding protein 3 (IGFBP3), transcript variant 2 |
USD 620.00 |
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