CD4 (NM_000616) Human Untagged Clone

CAT#: SC119790

CD4 (untagged)-Human CD4 molecule (CD4), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CD4
• Synonyms: CD4mut
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_000616 edited
  GAATTCGGCACGAGGCAGAGCTCCAAGTCCTCACACAGATACGCCTGTTTGAGAAGCAGC
  GGGCAAGAAAGACGCAAGCCCAGAGGCCCTGCCATTTCTGTGGGCTCAGGTCCCTACTGG
  CTCAGGCCCCTGCCTCCCTCGGCAAGGCCACAATGAACCGGGGAGTCCCTTTTAGGCACT
  TGCTTCTGGTGCTGCAACTGGCGCTCCTCCCAGCAGCCACTCAGGGAAAGAAAGTGGTGC
  TGGGCAAAAAAGGGGATACAGTGGAACTGACCTGTACAGCTTCCCAGAAGAAGAGCATAC
  AATTCCACTGGAAAAACTCCAACCAGATAAAGATTCTGGGAAATCAGGGCTTCTTCTTAA
  CTAAAGGTCCATCCAAGCTGAATGATCGCGCTGACTCAAGAAGAAGCCTTTGGGACCAAG
  GAAACTTTCCCCTGATCATCAAGAATCTTAAGATAGAAGACTCAGATACTTACATCTGTG
  AAGTGGAGGACCAGAAGGAGGAGGTGCAATTGCTAGTGTTCGGATTGACTGCCAACTCTG
  ACACCCACCTGCTTCAGGGGCAGAGCCTGACCCTGACCTTGGAGAGCCCCCCTGGTAGTA
  GCCCCTCAGTGCAATGTAGGAGTCCAAGGGGTAAAAACATACAGGGGGGGAAGACCCTCT
  CCGTGTCTCAGCTGGAGCTCCAGGATAGTGGCACCTGGACATGCACTGTCTTGCAGAACC
  AGAAGAAGGTGGAGTTCAAAATAGACATCGTGGTGCTAGCTTTCCAGAAGGCCTCCAGCA
  TAGTCTATAAGAAAGAGGGGGAACAGGTGGAGTTCTCCTTCCCACTCGCCTTTACAGTTG
  AAAAGCTGACGGGCAGTGGCGAGCTGTGGTGGCAGGCGGAGAGGGCTTCCTCCTCCAAGT
  CTTGGATCACCTTTGACCTGAAGAACAAGGAAGTGTCTGTAAAACGGGTTACCCAGGACC
  CTAAGCTCCAGATGGGCAAGAAGCTCCCGCTCCACCTCACCCTGCCCCAGGCCTTGCCTC
  AGTATGCTGGCTCTGGAAACCTCACCCTGGCCCTTGAAGCGAAAACAGGAAAGTTGCATC
  AGGAAGTGAACCTGGTGGTGATGAGAGCCACTCAGCTCCAGAAAAATTTGACCTGTGAGG
  TGTGGGGACCCACCTCCCCTAAGCTGATGCTGAGTTTGAAACTGGAGAACAAGGAGGCAA
  AGGTCTCGAAGCGGGAGAAGGCGGTGTGGGTGCTGAACCCTGAGGCGGGGATGTGGCAGT
  GTCTGCTGAGTGACTCGGGACAGGTCCTGCTGGAATCCAACATCAAGGTTCTGCCCACAT
  GGTCCACCCCGGTGCAGCCAATGGCCCTGATTGTGCTGGGGGGCGTCGCCGGCCTCCTGC
  TTTTCATTGGGCTAGGCATCTTCTTCTGTGTCAGGTGCCGGCACCGAAGGCGCCAAGCAG
  AGCGGATGTCTCAGATCAAGAGACTCCTCAGTGAGAAGAAGACCTGCCAGTGTCCTCACC
  GGTTTCAGAAGACATGTAGCCCCATTTGAGGCACGAGGCCAGGCAGATCCCACTTGCAGC
  CTCCCCAGGTGTCTGCCCCGCGTTTCCTGCCTGCGGACCAGATGAATGTAGCAGATCCCA
  GGCCTCTGGCCTCCTGTTCGCCTCCTCTACAATTTGCCATTGTTTCTCCTGGGTTAGGCC
  CCGGCTTCACTGGTTGAGTGTTGCTCTCTAGTTTCCAGAGGCTTAATCACACCGTCCTCC
  ACGCCATTTCCTTTTCCTTCAAGCCTAGCCCTTCTCTCATCATTTCTCTCTGACCCTCTC
  CCCACTGCTCATTTGGATCCCAGGGGAGTGTTCAGGGCCAGCCCTGGCTGGCATGGAGGG
  TGAGGCTGGGTGTCTGGAAGCATGGAGCATGGGACTGTTCTTTTACAAGACAGGACCCTG
  GGACCACAGAGGGCAGGAACTTGCACAAAATCACACAGCCAAGCCAGTCAAGGATGGATG
  CAGATCCAGAGGTTTCTGGCAGCCAGTACCTCCTGCCCCATGCTGCCCGCTTCTCACCCT
  ATGTGGGTGGGGCCACAGACTCACATCCTGACCTTGCACAAACAGCCCCTCTGGACACAG
  CCCCATGTACACGGCCTCAAGGGATGTCTCACATCCTCTGTCTATTTGAGACTTAGAAAA
  ATCCTACAAGGCTGGCAGTGACAGAACTAAGATGATCATCTCCAGTTTATAGACCAGAAC
  CAGAGCTCAGAGAGGCTAGATGATTGATTACCAAGTGCCGGACTAGCAAGTGCTGGAGTC
  GGGACTAACCCAGGTCCCTTGTCCCAAGTTCCACTGCTGCCTCTTGAATGCAGGGACAAA
  TGCCACACGGCTCTCACCAGTGGCTAGTGGTGGGTACTCAATGTGTACTTTTGGGTTCAC
  AGAAGCACAGCACCCATGGGAAGGGTCCATCTCAGAGAATTTACGAGCAGGGATGAAGGC
  CTCCCTGTCTAAAATCCCTCCTTCATCCCCCGCTGGTGGCAGAATCTGTTACCAGAGGAC
  AAAGCCTTTGGCTCTTCTAATCAGAGCGCAAGCTGGGAGCACAGGCACTGCAGGAGAGAA
  TGCCCAGTGACCAGTCACTGACCCTGTGCAGAACCTCCTGGAAGCGAGCTTTGCTGGGAG
  AGGGGGTAGCTAGCCTGAGAGGGAACCCTCTAAGGGACCTCAAAGGTGATTGTGCCAGGC
  TCTGCGCCTGCCCCACACCCTCCCTTACCCTCCTCCAGACCATTCAGGACACAGGGAAAT
  CAGGGTTACAAATCTTCTTGATCCACTTCTCTCAGGATCCCCTCTCTTCCTACCCTTCCT
  CACCACTTCCCTCAGTCCCAACTCCTTTTCCCTATTTCCTTCTCCTCCTGTCTTTAAAGC
  CTGCCTCTTCCAGGAAGACCCCCCTATTGCTGCTGGGGCTCCCCATTTGCTTACTTTGCA
  TTTGTGCCCACTCTCCACCCCTGCTCCCCTGAGCTGAAATAAAAATACAATAAACTTACT
  ATAAAGATGAAAAAAAAAAAAAAAAAACTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000616 unedited
  GGTTCAAATTTGTATACGACTCACTATAGGCGGCCGCGAATCGGCACGAGGCAGAGCTCC
  AAGTCCTCACACAGATACGCCTGTTTGAGAAGCAGCGGGCAAGAAAGACGCAAGCCCAGA
  GGCCCTGCCATTTCTGTGGGCTCAGGTCCCTACTGGCTCAGGCCCCTGCCTCCCTCGGCA
  AGGCCACAATGAACCGGGGAGTCCCTTTTAGGCACTTGCTTCTGGTGCTGCAACTGGCGC
  TCCTCCCAGCAGCCACTCAGGGAAAGAAAGTGGTGCTGGGCAAAAAAGGGGATACAGTGG
  AACTGACCTGTACAGCTTCCCAGAAGAAGAGCATACAATTCCACTGGAAAAACTCCAACC
  AGATAAAGATTCTGGGAAATCAGGGCTTCTTCTTAACTAAAGGTCCATCCAAGCTGAATG
  ATCGCGCTGACTCAAGAAGAAGCCTTTGGGACCAAGGAAACTTTCCCCTGATCATCAAGA
  ATCTTAAGATAGAAGACTCAGATACTTACATCTGTGAAGTGGAGGACCAGAAGGAGGAGG
  TGCAATTGCTAGTGTTCGGATTGACTGCCAACTCTGACACCCACCTGCTTCAGGGGCAGA
  GCCTGACCCTGACCTTGGAGAGCCCCCCTGGTAGTAGCCCCTCAGTGCAATGTAGGAGTC
  CAAGGGGTAAAAACATACAGGGGGGGAAGACCCTCTCCGTGTCTCAGCTGGAGCTCCAGG
  ATAGTGGCACCTGGACATGCACTGTCTTGCAGAACCAGAAGAAAGTGGAGTTCAAAATAG
  ACATCGTGGTGCTAGCTNTCCAGAAGCCTNCAGCATAGTCTATAAGAAAGAAGGGGACAG
  GTGGAGTTCTCCTTCCACTCGCCTTTACCAGTGAAAGCTGACGGGCANTGGCGAACTGTG
  GTGGCANGGCGGAAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000616 unedited
  CGCTTTTAAAGTGAGTTTTTTTTTTTTTTTTTTAATCTTTATAGAAAGTTTATTGTATTT
  TTATTTCAGCTCAGGGGAGCAGGGGTGGAGAGTGGGCACAAATGCAAAGTAAGCAAATGG
  GGAGCCCCAGCAGCAATAGGGGGGTCTTCCTGGAAGAGGCAGGCTTTAAAGACAGGAGGA
  GAAGGAAATAGGGAAAAGGAGTTGGGACTGAGGGAAGTGGTGAGGAAGGGTAGGAAGAGA
  GGGGATCCTGAGAGAAGTGGATCAAGAAGATTTGTAACCCTGATTTCCCTGTGTCCTGAA
  TGGTCTGGAGGAGGGTAAGGGAGGGTGTGGGGCAGGCGCATAGCCTGGCACAATCACCTT
  TGAGGTCCCTTAGAGGGTTCCCTCTCAGGCTAGCTACCCCCTCTCCCAGCAAAGCTCGCT
  TCCAGGAGGTTCTGCACAGGGTCAGTGACTGGTCACTGGGCATTCTCTCCTGCAGTGCCT
  GTGCTCCCAGCTTGCGCTCTGATTATAAGAGCCAAAGGCTTTGACCTCTGGTAACAGATT
  CTGCCACCAGCGGGGGATGAAGGAGGGATTTTAGACAGGGAGGCCTTCATCCCTGCTCGA
  AAATTCTCTGAGATGGACCCTTCCCATGGGTGCTGTGCTTCTGTGAACCCATAAGCACAC
  ATTGAGTACCCCACCACTACCCACTGGTGAGAGCCGTGCGGCATTTGACCCTGCCTTCAA
  GAAGCAATAGTGGAACTTGGGACAAGGACCTGGGTTACCTCCGACTCAACACCTTGCTAT
  ACGGCCCTCGCGCATAATCTTTTACCTCTCTAGCCTCTGCTCCGCATTTTTCCCGCGCAG
  TCTCCCCTCCCTCCTTGCCCTCCCTTTTCTCACCCACCTTCTATTTTCCTCCTCCCCTCT
  CGTCTCCCTCGACCTTTTCCTTCTCTCTCCCATCTTCTCCCTCCTCCCCCCCTCCCCCCT
  CCCCCTCGTCTCTCCCTTCCAT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_000616
• ORF Size: 1377 bp
• Insert Size: 3070
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_000616.2, NP_000607.1
• RefSeq Size: 3084
• RefSeq ORF: 1377
• Locus ID: 920
• Domains: ig, IGv, IGc2, IG
• Protein Families: Adult stem cells, Druggable Genome, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transmembrane
• Protein Pathways: Antigen processing and presentation, Cell adhesion molecules (CAMs), Hematopoietic cell lineage, Primary immunodeficiency, T cell receptor signaling pathway
• Gene Summary: This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Aug 2010]
  Transcript Variant: This variant (1) encodes the longest isoform (1) including a signal peptide and a mature peptide. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.