PEX1 (NM_000466) Human Untagged Clone

CAT#: SC119848

PEX1 (untagged)-Human peroxisomal biogenesis factor 1 (PEX1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PEX1
• Synonyms: HMLR1; PBD1A; PBD1B; ZWS; ZWS1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_000466, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTGGGGCAGCGATCGCCTGGCGGGTGCTGGGGGAGGCGGGGCGGCAGTGACTGTGGCCTTCACCAACG
  CTCGCGACTGCTTCCTCCACCTGCCGCGGCGTCTCGTGGCCCAGCTGCATCTGCTGCAGAATCAAGCTAT
  AGAAGTGGTCTGGAGTCACCAGCCTGCATTCTTGAGCTGGGTGGAAGGCAGGCATTTTAGTGATCAAGGT
  GAAAATGTGGCTGAAATTAACAGACAAGTTGGTCAAAAACTTGGACTCTCAAATGGGGGACAGGTATTTC
  TCAAGCCATGTTCCCATGTGGTATCTTGTCAACAAGTTGAGGTGGAACCCCTCTCAGCAGATGATTGGGA
  GATACTGGAGCTGCATGCTGTTTCCCTTGAACAACATCTTCTAGATCAAATTCGAATAGTTTTTCCAAAA
  GCCATTTTTCCTGTTTGGGTTGATCAACAAACGTACATATTTATCCAAATTGTTGCACTAATACCAGCTG
  CCTCTTATGGAAGGCTGGAAACTGACACCAAACTCCTTATTCAGCCAAAGACACGCCGAGCCAAAGAGAA
  TACATTTTCAAAAGCTGATGCTGAATATAAAAAACTTCATAGTTATGGAAGAGACCAGAAAGGAATGATG
  AAAGAACTTCAAACCAAGCAACTTCAGTCAAATACTGTGGGAATCACTGAATCTAATGAAAACGAGTCAG
  AGATTCCAGTTGACTCATCATCAGTAGCAAGTTTATGGACTATGATAGGAAGCATTTTTTCCTTTCAATC
  TGAGAAGAAACAAGAGACATCTTGGGGTTTAACTGAAATCAATGCATTCAAAAATATGCAGTCAAAGGTT
  GTTCCTCTAGACAATATTTTCAGAGTATGCAAATCTCAACCTCCTAGTATATATAACGCGTCAGCAACCT
  CTGTTTTTCATAAACACTGTGCCATTCATGTATTTCCATGGGACCAGGAATATTTTGATGTAGAGCCCAG
  CTTTACTGTGACATATGGAAAGCTAGTTAAGCTACTTTCTCCAAAGCAACAGCAAAGTAAAACAAAACAA
  AATGTGTTATCACCTGAAAAAGAGAAGCAGATGTCAGAGCCACTAGATCAAAAAAAAATTAGGTCAGATC
  ATAATGAAGAAGATGAGAAGGCCTGTGTGCTACAAGTAGTCTGGAATGGACTTGAAGAATTGAACAATGC
  CATCAAATATACCAAAAATGTAGAAGTTCTCCATCTTGGGAAAGTCTGGATTCCAGATGACCTGAGGAAG
  AGACTAAATATAGAAATGCATGCCGTAGTCAGGATAACTCCAGTGGAAGTTACCCCTAAAATTCCAAGAT
  CTCTAAAGTTACAACCTAGAGAGAATTTACCTAAAGACATAAGTGAAGAAGACATAAAAACTGTATTTTA
  TTCATGGCTACAGCAGTCTACTACCACCATGCTTCCTTTGGTAATATCAGAGGAAGAATTTATTAAGCTG
  GAAACTAAAGATGGACTGAAGGAATTTTCTCTGAGTATAGTTCATTCTTGGGAAAAAGAAAAAGATAAAA
  ATATTTTTCTGTTGAGTCCCAATTTGCTGCAGAAGACTACAATACAAGTCCTTCTAGATCCTATGGTAAA
  AGAAGAAAACAGTGAGGAAATTGACTTTATTCTTCCTTTTTTAAAGCTGAGCTCTTTGGGAGGAGTGAAT
  TCCTTAGGCGTATCCTCCTTGGAGCACATCACTCACAGCCTCCTGGGACGCCCTTTGTCTCGGCAGCTGA
  TGTCTCTTGTTGCAGGACTTAGGAATGGAGCTCTTTTACTCACAGGAGGAAAGGGAAGTGGAAAATCAAC
  TTTAGCCAAAGCAATCTGTAAAGAAGCATTTGACAAACTGGATGCCCATGTGGAGAGAGTTGACTGTAAA
  GCTTTACGAGGAAAAAGGCTTGAAAACATACAAAAAACCCTAGAGGTGGCTTTCTCAGAGGCAGTGTGGA
  TGCAGCCATCTGTTGTCCTGCTGGATGACCTTGACCTCATTGCTGGACTGCCTGCTGTCCCGGAACATGA
  GCACAGTCCTGATGCGGTGCAGAGCCAGCGGCTTGCTCATGCTTTGAATGATATGATAAAAGAGTTTATC
  TCCATGGGAAGTTTGGTTGCACTGATTGCCACAAGTCAGTCTCAGCAATCTCTACATCCTTTACTTGTTT
  CTGCTCAAGGAGTTCACATATTTCAGTGCGTCCAACACATTCAGCCTCCTAATCAGGAACAAAGATGTGA
  AATTCTGTGTAATGTAATAAAAAATAAATTGGACTGTGATATAAACAAGTTCACCGATCTTGACCTGCAG
  CATGTAGCTAAAGAAACTGGCGGGTTTGTGGCTAGAGATTTTACAGTACTTGTGGATCGAGCCATACATT
  CTCGACTCTCTCGTCAGAGTATATCCACCAGAGAAAAATTAGTTTTAACAACATTGGACTTCCAAAAGGC
  TCTCCGCGGATTTCTTCCTGCGTCTTTGCGAAGTGTCAACCTGCATAAACCTAGAGACCTGGGTTGGGAC
  AAGATTGGTGGGTTACATGAAGTTAGGCAGATACTCATGGATACTATCCAGTTACCTGCCAAGTATCCAG
  AATTATTTGCAAACTTGCCCATACGACAAAGAACAGGAATACTGTTGTATGGTCCGCCTGGAACAGGAAA
  AACCTTACTAGCTGGGGTAATTGCACGAGAGAGTAGAATGAATTTTATAAGTGTCAAGGGGCCAGAGTTA
  CTCAGCAAATACATTGGAGCAAGTGAACAAGCTGTTCGGGATATTTTTATTAGAGCACAGGCTGCAAAGC
  CCTGCATTCTTTTCTTTGATGAATTTGAATCCATTGCTCCTCGGCGGGGTCATGATAATACAGGAGTTAC
  AGACCGAGTAGTTAACCAGTTGCTGACTCAGTTGGATGGAGTAGAAGGCTTACAGGGTGTTTATGTATTG
  GCTGCTACTAGTCGCCCTGACTTGATTGACCCTGCCCTGCTTAGGCCTGGTCGACTAGATAAATGTGTAT
  ACTGTCCTCCTCCTGATCAGGTGTCACGTCTTGAAATTTTAAATGTCCTCAGTGACTCTCTACCTCTGGC
  AGATGATGTTGACCTTCAGCATGTAGCATCAGTAACTGACTCCTTTACTGGAGCTGATCTGAAAGCTTTA
  CTTTACAATGCCCAATTGGAGGCCTTACATGGAATGCTGCTCTCGAGTGGACTCCAGGATGGAAGTTCCA
  GCTCTGATAGTGACCTAAGTCTGTCTTCAATGGTCTTTCTTAACCATAGCAGTGGCTCTGACGATTCAGC
  TGGAGATGGAGAATGTGGCTTAGATCAGTCCCTTGTTTCTTTAGAGATGTCCGAGATCCTTCCAGATGAA
  TCAAAATTCAATATGTACCGGCTCTACTTTGGAAGCTCTTATGAATCAGAACTTGGAAATGGAACCTCTT
  CTGATTTGAGCTCACAATGTCTCTCTGCACCAAGCTCCATGACTCAGGATTTGCCTGGAGTTCCTGGGAA
  AGACCAGTTGTTTTCACAGCCTCCAGTGTTAAGGACAGCTTCACAAGAGGGTTGCCAAGAACTTACACAA
  GAACAAAGAGATCAACTGAGGGCAGATATCAGTATTATCAAAGGCAGATACCGGAGCCAAAGTGGAGAGG
  ACGAATCCATGAACCAACCAGGACCAATCAAAACCAGACTGGCTATTAGTCAGTCACATTTAATGACTGC
  ACTTGGTCACACAAGACCATCCATTAGTGAAGATGACTGGAAGAATTTTGCTGAGCTATATGAAAGCTTT
  CAAAATCCAAAGAGGAGAAAAAATCAAAGTGGAACAATGTTTCGACCTGGACAGAAAGTAACTTTAGCAT
  AA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000466 unedited
  TCGGATTTTGTNATACGACTCACTATAGGGCGGCCGCGNAATTCGCACGAGGCGACGCTC
  CGGGACGATGTGGGGCAGCGATCGCCTGGCGGGTGCTGGGGGAGGCGGGGCGGCAGTGAC
  TGTGGCCTTCACCAACGCTCGCGACTGCTTCCTCCACCTGCCGCGGCGTCTCGTGGCCCA
  GCTGCATCTGCTGCAGAATCAAGCTATAGAAGTGGTCTGGAGTCACCAGCCTGCATTCTT
  GAGCTGGGTGGAAGGCAGGCATTTTAGTGATCAAGGTGAAAATGTGGCTGAAATTAACAG
  ACAAGTTGGTCAAAAACTTGGACTCTCAAATGGGGGACAGGTATTTCTCAAGCCATGTTC
  CCATGTGGTATCTTGTCAACAAGTTGAGGTGGAACCCCTCTCAGCAGATGATTGGGAGAT
  ACTGGAGCTGCATGCTGTTTCCCTTGAACAACATCTTCTAGATCAAATTCGAATAGTTTT
  TCCAAAAGCCATTTTTCCTGTTTGGGTTGATCAACAAACGTACATATTTATCCAAATTGT
  TGCACTAATACCAGCTGCCTCTTATGGAAGGCTGGAAACTGACACCAAACTCCTTATTCA
  GCCAAAGACACGCCGAGCCAAAGAGAATACATTTTCAAAAGCTGATGCTGAATATAAAAA
  ACTTCATAGTTATGGAAGAGACCAGAAAGGAATGATGAAAGAACTTCAAACCAAGCAACT
  TCAGTCAAATACTGTGGGAATCACTGAATCTAATGAAAACGAGTCAGAGATTCCAGTTGA
  CTCATCATCAGTAGCAAGTTTATGGACTATGATAGGAAGCATTNTTTCCTTTCATCTGAG
  AAGAACAAGAGACATCTGGGGTTTAACTGAAATCATGCATTCNAATATGCAGTCAAAGGT
  GNTCCCTCTAGACATATTTCAGATATGCAAAN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000466 unedited
  TGGACCGCGGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTCAGTAGGTAATAG
  GATATTTTATTTCAAAACAGTGAAGAAGCTGCTAAGCATAAAATTTGTCAAATGCTACAA
  AGGTGATGAATATACAACTGGGAATTCCAAGAAATTTAAATTTAATTACATTCTTTATTA
  TCTTTTCCTCAAAAAAAATAAATTAGTTCCACCATTTGGCTAATATTATTTCATTAAAGA
  CTGAATTTAGATTTTAGGAAATAAAATATGGAATCTGTTATAATGTCCCAATTTATACTA
  CAGTATTAATCTCAATCCTGATCATTACATAATTATAGCATTTACCAATCTGTGATTTTA
  TAAATTAACCAAATTTGTTAAATTAAGAAGAAATTCATAGACACCATTTTTTTCCTGTTA
  CAACATATGGAAAAGCCATCAAAAAACTTAACAGAACCAAATCAAAAAGAAGTATATTTT
  ATGCTAAAGTTACTTTCTGTCCAGGTCGAAACATTGTTCCACTTTGATTTTTTCTCCTCT
  TTGGATTTTGAAAGCTTTCATATAGCTCAGCAAAATTCTTCCAGTCATCTTCACTAATGG
  ATGGTCTTGTGTGACCAAGTGCAGTCATTAAATGTGACTGACTAATAGCCAGTCTGGTTT
  TGATTGGTCCTGGTTGGTTCATGGATTCGTCCTCTCCACTTTGGCTCCGGTATCTGCCTT
  TGATATACTGATATCTGCCCTCAGTTGATCTCTTTGNTCTTGNGNAAGTTCTTGGNCACC
  CTCTTGTGAAGCTGTCCTTTACACTGGNAGCTGNGNNAAACACTGGTTCTTTCCAGNAAC
  TNNCAGGCAATNCTGAGTCATGGAGCTTGGTGCANAGAGACATTGTGAGCTCAATCANAA
  GAGTTNCCATTTTCCAGNNTCTGATCATAGAAAGCTCCAAGTN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_000466
• Insert Size: 4940 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000466.1, NP_000457.1
• RefSeq Size: 4390 bp
• RefSeq ORF: 3852 bp
• Locus ID: 5189
• Cytogenetics: 7q21.2
• Domains: AAA, AAA
• Protein Families: Druggable Genome
• Gene Summary: 'This gene encodes a member of the AAA ATPase family, a large group of ATPases associated with diverse cellular activities. This protein is cytoplasmic but is often anchored to a peroxisomal membrane where it forms a heteromeric complex and plays a role in the import of proteins into peroxisomes and peroxisome biogenesis. Mutations in this gene have been associated with complementation group 1 peroxisomal disorders such as neonatal adrenoleukodystrophy, infantile Refsum disease, and Zellweger syndrome. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013]'
  Transcript Variant: This variant (1) encodes the longest isoform (1).