C1QB (NM_000491) Human Untagged Clone

CAT#: SC119857

C1QB (untagged)-Human complement component 1, q subcomponent, B chain (C1QB)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: C1QB
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC119857 sequence for NM_000491 edited (data generated by NextGen Sequencing)
  ATGATGATGAAGATCCCATGGGGCAGCATCCCAGTACTGATGTTGCTCCTGCTCCTGGGC
  CTAATCGATATCTCCCAGGCCCAGCTCAGCTGCACCGGGCCCCCAGCCATCCCTGGCATC
  CCGGGTATCCCTGGGACACCTGGCCCCGATGGCCAACCTGGGACCCCAGGGATAAAAGGA
  GAGAAAGGGCTTCCAGGGCTGGCTGGAGACCATGGTGAGTTCGGAGAGAAGGGAGACCCA
  GGGATTCCTGGGAATCCAGGAAAAGTCGGCCCCAAGGGCCCCATGGGCCCTAAAGGTGGC
  CCAGGGGCCCCTGGAGCCCCAGGCCCCAAAGGTGAATCGGGAGACTACAAGGCCACCCAG
  AAAATCGCCTTCTCTGCCACAAGAACCATCAACGTCCCCCTGCGCCGGGACCAGACCATC
  CGCTTCGACCACGTGATCACCAACATGAACAACAATTATGAGCCCCGCAGTGGCAAGTTC
  ACCTGCAAGGTGCCCGGTCTCTACTACTTCACCTACCACGCCAGCTCTCGAGGGAACCTG
  TGCGTGAACCTCATGCGTGGCCGGGAGCGTGCACAGAAGGTGGTCACCTTCTGTGACTAT
  GCCTACAACACCTTCCAGGTCACCACCGGTGGCATGGTCCTCAAGCTGGAGCAGGGGGAG
  AACGTCTTCCTGCAGGCCACCGACAAGAACTCACTACTGGGCATGGAGGGTGCCAACAGC
  ATCTTTTCCGGGTTCCTGCTCTTTCCAGATATGGAGGCCTGA
  
  Clone variation with respect to NM_000491.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000491 unedited
  GTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGCACTGCTGCTCAGCCCAG
  TGGCCTCACAGGACACCAGCTTCCCAGGAGGCGTCTGACACAGTATGATGATGAAGATCC
  CATGGGGCAGCATCCCAGTACTGATGTTGCTCCTGCTCCTGGGCCTAATCGATATCTCCC
  AGGCCCAGCTCAGCTGCACCGGGCCCCCAGCCATCCCTGGCATCCCGGGTATCCCTGGGA
  CACCTGGCCCCGATGGCCAACCTGGGACCCCAGGGATAAAAGGAGAGAAAGGGCTTCCAG
  GGCTGGCTGGAGACCATGGTGAGTTCGGAGAGAAGGGAGACCCAGGGATTCCTGGGAATC
  CAGGAAAAGTCGGCCCCAAGGGCCCCATGGGCCCTAAAGGTGGCCCAGGGGCCCCTGGAG
  CCCCAGGCCCCAAAGGTGAATCGGGAGACTACAAGGCCACCCAGAAAATCGCCTTCTCTG
  CCACAAGAACCATCAACGTCCCCCTGCGCCGGGACCAGACCATCCGCTTCGACCACGTGA
  TCACCAACATGAACAACAATTATGAGCCCCGCAGTGGCAAGTTCACCTGCAAGGTGCCCG
  GTCTCTACTACTTCACCTACCACGCCAGCTCTCGAGGGAACCTGTGCGTGAACCTCATGC
  GTGGCCGGGAGCGTGCACAGAAGGTGGTCACCTTCTGTGACTATGCCTACNACACCTTTC
  AGGTCACCACCCGTTGGCATGGTCCCTCAAGCTGGAGCAAGGGGGAGAACGTCTTCCTGC
  AAGCCACCGACAAGAACTCACTACTGGGCATGGAGGGTGCCAACAGCATCTTTTTCGGGT
  TCCTGCTCTTTCCAGATTTGGAGGCCTGACTCTGGGGCTGTTTCAATTCCCCCGGTCTCC
  CT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000491 unedited
  TCTAGAGTCGAGNTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGGCCCTGAAGAGTTT
  ATTTACTCATTCACTCAGCAGCATTCACCAAGCCCTACTGTGTGCATTGGCTGGGCAAGG
  GGTGGTGTTGGGGGTAAAATGAACGTTGCTGGCAAGGGGAACCCGGGTGGATGTGAAACA
  ACCCACAGGTCAAGCCTCCATATTTGGAAAGAACAAGAACCCGGAAAAAATGCTGTTGGC
  ACCCTCCATGCCCAATAGTGAGTTCTTGTCGGTGGCCTGCAAGAAAACCTTCTTCCCCTG
  CTCCAGCTTGAGGACCATGCCACCGGTGGTGACCTGGAAAGTGTTGTAAGCATAATCACA
  AAAGGTGACCACCTTTTGTGCACGCTTCCGGCCACGCATGAGGTTCACGCACAGGTTCCC
  TCGAAAGCTGGCGCGGTACGTGAAATAATAAAGACCGGGCACCTTTGACGTGAACTTGCC
  ACTGCGGGGCCCAATAATTGCCGGTCATGTTGGTGAACCCTTGGTCCAAACCGATGGATT
  GGTCCCCGCGCAAGGGGACCTTTATTGGCCTTTGTGGCAAAAACCGCATTTTCCGGTTGC
  CTTGAATTTACCGATTAACTTTGGGGCCCGGGCCTCAAGGCCCCCTGGTCCCCTTTGGCC
  CTTGGCGCCCTGGCGCTACCTCCTTTGGACCTCTAAACACCTCGGTTTCCTTTTTCTACA
  TTCCACTGCCCTTACCACCTTCGAATTCCCTTCCCTTTTTTTTTGTTGCCCCCTTTACCC
  CATGTTCCCAAATACGCCCCCCCCTCACCCATTTCACCAACCCGTTTTTATTCTCCCCCC
  TCCCGTTCCCTTTTTCTCTCCCCCTAAATATTCCCCCCTTCTTACTCTCCCTATTTCCCT
  TTCTTCCATACTCCCCCTTACTTCCCATTTTCCTTTTCCCCTCGTCCACTTACTCCTCCC
  ACCT
  
• Restriction Sites: ECoRI-NOT
• ACCN: NM_000491
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000491.2, NP_000482.2
• RefSeq Size: 1072 bp
• RefSeq ORF: 1044 bp
• Locus ID: 713
• Cytogenetics: 1p36.12
• Domains: C1Q, Collagen
• Protein Families: Secreted Protein
• Protein Pathways: Complement and coagulation cascades, Prion diseases, Systemic lupus erythematosus
• Gene Summary: 'This gene encodes the B-chain polypeptide of serum complement subcomponent C1q, which associates with C1r and C1s to yield the first component of the serum complement system. C1q is composed of 18 polypeptide chains which include 6 A-chains, 6 B-chains, and 6 C-chains. Each chain contains an N-terminal collagen-like region and a C-terminal C1q globular domain. C1q deficiency is associated with lupus erythematosus and glomerulonephritis. [provided by RefSeq, Dec 2016]'