PEX7 (NM_000288) Human Untagged Clone

CAT#: SC119985

PEX7 (untagged)-Human peroxisomal biogenesis factor 7 (PEX7)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PEX7
• Synonyms: PBD9B; PTS2R; RCDP1; RD
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_000288, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAGTGCGGTGTGCGGTGGAGCGGCGCGGATGCTGCGGACGCCGGGACGCCACGGCTACGCCGCCGAGT
  TCTCCCCGTACCTGCCGGGCCGCCTGGCCTGCGCCACCGCGCAGCACTACGGCATCGCGGGCTGTGGAAC
  CCTACTAATATTGGATCCAGATGAAGCTGGGCTAAGGCTTTTTAGAAGCTTTGACTGGAATGATGGTTTG
  TTTGATGTGACTTGGAGTGAGAACAACGAACATGTCCTCATCACCTGTAGTGGCGATGGCTCGCTGCAGC
  TCTGGGACACTGCCAAAGCTGCAGGGCCACTGCAAGTCTATAAAGAACACGCTCAGGAGGTGTATAGTGT
  TGATTGGAGCCAAACCAGAGGTGAACAGCTTGTGGTGTCTGGCTCATGGGATCAAACTGTCAAATTGTGG
  GATCCAACTGTTGGAAAGTCTCTGTGCACCTTTAGAGGCCATGAAAGTATTATTTATAGCACAATCTGGT
  CTCCCCACATCCCTGGTTGTTTTGCTTCAGCCTCAGGTGATCAGACTCTGAGAATATGGGATGTGAAGGC
  AGCAGGAGTAAGAATCGTGATTCCTGCACATCAGGCAGAAATCTTGAGTTGTGACTGGTGTAAATACAAT
  GAGAATTTGCTGGTGACCGGGGCGGTTGACTGTAGTTTGAGAGGCTGGGACTTAAGGAATGTACGACAAC
  CAGTGTTTGAACTTCTTGGTCATACCTATGCTATTAGGAGGGTGAAATTTTCACCATTTCATGCTTCTGT
  GCTGGCCTCTTGCTCGTATGATTTTACTGTAAGATTCTGGAACTTTTCAAAGCCTGACTCTCTTCTTGAA
  ACAGTGGAGCATCATACAGAGTTTACTTGTGGTTTAGACTTCAGTCTTCAGAGCCCCACTCAGGTGGCTG
  ACTGTTCTTGGGATGAAACAATAAAGATCTATGACCCTGCTTGTCTTACTATTCCTGCTTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000288 unedited
  AAAAAAGGTGCGNGATTAGTATACGACTCATATAGGGCGGCCGCGATTCGGCACGAGGCC
  GACTCGGNACGGCTTCCGCGGCCGGGGCAGCGAGGGCCGGGGGCGGCGGGCGGGATGAGT
  GCGGTGTGCGGTGGAGCGGCGCGGATGCTGCGGACGCCGGGACGCCACGGCTACGCCGCC
  GAGTTCTCCCCGTACCTGCCGGGCCGCCTGGCCTGCGCCACCGCGCAGCACTACGGCATC
  GCGGGCTGTGGAACCCTACTAATATTGGATCCAGATGAAGCTGGGCTAAGGCTTTTTAGA
  AGCTTTGACTGGAATGATGGTTTGTTTGATGTGACTTGGAGTGAGAACAACGAACATGTC
  CTCATCACCTGTAGTGGCGATGGCTCGCTGCAGCTCTGGGACACTGCCAAAGCTGCAGGG
  CCACTGCAAGTCTATAAAGAACACGCTCAGGAGGTGTATAGTGTTGATTGGAGCCAAACC
  AGAGGTGAACAGCTTGTGGTGTCTGGCTCATGGGATCAAACTGTCAAATTGTGGGATCCA
  ACTGTTGGAAAGTCTCTGTGCACCTTTAGAGGCCATGAAAGTATTATTTATAGCACAATC
  TGGTCTCCCCACATCCCTGGTTGTTTTGCTTCAGCCTCAGGTGATCAGACTCTGAGAATA
  TGGGATGTGAAGGCAGCAGGAGTTAGAATCGGGATTCCTGCACCTNAGGCACAAATCCTG
  AATTGTGACTGGTGTAAATACAATGAGTATTTGCCTGGTGACCGTGGCGGTTGACTGTAT
  TTTGAGAGGCTGGCACTAAGGAATGTCCCAAACCCGTGGTTGAACTTTTTTGGTCTACCC
  ATGCTTTAAGAGGGTGGAATTTTCACCATTCTAGCCTCTCGGCTGGCCCTTTGTTCGAAG
  ATTTAACGCT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000288 unedited
  ATGCCCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTAGGTT
  TTAAATTACAAGTCTTTGTTTCCAAAAAACGTGATAAAACGTTTTGTTAATAAAAATCTC
  TTGCCTTCTAAAAGGAAAGGAAATAATTTCATTTCATTGTAAATATTATCTGGGTTAGAT
  ATTTTCTGAAACAAGGTCTGTCACCTAGGCTGGAATGCCTTAATCTGGGTCACTGCAGCC
  TCAACTTCCCAGGATCAAGCAATCCTCCTGCCTTAGCCTCCTGAGTATCTGGGACTACAG
  GCACACGTCACCATGCCTGACTACTTTGGGTTGGATACTTTTAGGGCCTATCACAAATTC
  TGCTGATACAGAGAACACCCATTGTAGACCCACTTTTACTGACCACACCTTGGTGTAATG
  CCATTAGTTCATATAGAGGCAAGCAGCAAGAAAAAAGGCTGTCAAACTCATCAGTGTGAC
  AACTCTAAGGATGTGGTTAAGCACCATGTTCCCTGCAGTATACTTAGGTTAAGCAGTGTC
  CTCTTTATGGGTCCTCTCAAAAGCAATCTGTATTGCTGATTCAAGAACCAAAAAAAAGTG
  GGCACTGTGGCATGTCCCCATATCCCCACGTAATTGGGAGCCTGAGGGGGAAGGAGGGCT
  TCAGCCTAGGATTCAAAACCCGTTTTGGGCAACATAGTGAGGCCCCATGCCTGACCCCCT
  TTTGTTGCCTGTGCCCAGCAAGTGGGCAGGGCCCAACCCTGCCCCAAGGCCAAAACCTGC
  CCCTCTGGCCCTAGCCCCTGACCTGCGAAACTGGTCACAATTCCTTTATCTTGAACCCCC
  AAACACTCACCGGCAATTTTTGGCCCCACCCCTATAACCTTTCAGGACCTTGCGGGATTC
  CTACACAACCCCCTTCTTTGCCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_000288
• Insert Size: 3270 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000288.1, NP_000279.1
• RefSeq Size: 1451 bp
• RefSeq ORF: 972 bp
• Locus ID: 5191
• Cytogenetics: 6q23.3
• Domains: WD40
• Protein Families: Druggable Genome
• Gene Summary: 'This gene encodes the cytosolic receptor for the set of peroxisomal matrix enzymes targeted to the organelle by the peroxisome targeting signal 2 (PTS2). Defects in this gene cause peroxisome biogenesis disorders (PBDs), which are characterized by multiple defects in peroxisome function. There are at least 14 complementation groups for PBDs, with more than one phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene have been associated with PBD complementation group 11 (PBD-CG11) disorders, rhizomelic chondrodysplasia punctata type 1 (RCDP1), and Refsum disease (RD). [provided by RefSeq, Oct 2008]'