FANCC (NM_000136) Human Untagged Clone

CAT#: SC120069

FANCC (untagged)-Human Fanconi anemia, complementation group C (FANCC)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FANCC
• Synonyms: FA3; FAC; FACC
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC120069 sequence for NM_000136 edited (data generated by NextGen Sequencing)
  ATGGCTCAAGATTCAGTAGATCTTTCTTGTGATTATCAGTTTTGGATGCAGAAGCTTTCT
  GTATGGGATCAGGCTTCCACTTTGGAAACCCAGCAAGACACCTGTCTTCACGTGGCTCAG
  TTCCAGGAGTTCCTAAGGAAGATGTATGAAGCCTTGAAAGAGATGGATTCTAATACAGTC
  ATTGAAAGATTCCCCACAATTGGTCAACTGTTGGCAAAAGCTTGTTGGAATCCTTTTATT
  TTAGCATATGATGAAAGCCAAAAAATTCTAATATGGTGCTTATGTTGTCTAATTAACAAA
  GAACCACAGAATTCTGGACAATCAAAACTTAACTCCTGGATACAGGGTGTATTATCTCAT
  ATACTTTCAGCACTCAGATTTGATAAAGAAGTTGCTCTTTTCACTCAAGGTCTTGGGTAT
  GCACCTATAGATTACTATCCTGGTTTGCTTAAAAATATGGTTTTATCATTAGCGTCTGAA
  CTCAGAGAGAATCATCTTAATGGATTTAACACTCAAAGGCGAATGGCTCCCGAGCGAGTG
  GCGTCCCTGTCACGAGTTTGTGTCCCACTTATTACCCTGACAGATGTTGACCCCCTGGTG
  GAGGCTCTCCTCATCTGTCATGGACGTGAACCTCAGGAAATCCTCCAGCCAGAGTTCTTT
  GAGGCTGTAAACGAGGCCATTTTGCTGAAGAAGATTTCTCTCCCCATGTCAGCTGTAGTC
  TGCCTCTGGCTTCGGCACCTTCCCAGCCTTGAAAAAGCAATGCTGCATCTTTTTGAAAAG
  CTAATCTCCAGTGAGAGAAATTGTCTGAGAAGGATCGAATGCTTTATAAAAGATTCATCG
  CTGCCTCAAGCAGCCTGCCACCCTGCCATATTCCGGGTTGTTGATGAGATGTTCAGGTGT
  GCACTCCTGGAAACCGATGGGGCCCTGGAAATCATAGCCACTATTCAGGTGTTTACGCAG
  TGCTTTGTAGAAGCTCTGGAGAAAGCAAGCAAGCAGCTGCGGTTTGCACTCAAGACCTAC
  TTTCCTTACACTTCTCCATCTCTTGCCATGGTGCTGCTGCAAGACCCTCAAGATATCCCT
  CGGGGACACTGGCTCCAGACACTGAAGCATATTTCTGAACTGCTCAGAGAAGCAGTTGAA
  GACCAGACTCATGGGTCCTGCGGAGGTCCCTTTGAGAGCTGGTTCCTGTTCATTCACTTC
  GGAGGATGGGCTGAGATGGTGGCAGAGCAATTACTGATGTCGGCAGCCGAACCCCCCACG
  GCCCTGCTGTGGCTCTTGGCCTTCTACTACGGCCCCCGTGATGGGAGGCAGCAGAGAGCA
  CAGACTATGGTCCAGGTGAAGGCCGTGCTGGGCCACCTCCTGGCAATGTCCAGAAGCAGC
  AGCCTCTCAGCCCAGGACCTGCAGACGGTAGCAGGACAGGGCACAGACACAGACCTCAGA
  GCTCCTGCACAACAGCTGATCAGGCACCTTCTCCTCAACTTCCTGCTCTGGGCTCCTGGA
  GGCCACACGATCGCCTGGGATGTCATCACCCTGATGGCTCACACTGCTGAGATAACTCAC
  GAGATCATTGGCTTTCTTGACCAGACCTTGTACAGATGGAATCGTCTTGGCATTGAAAGC
  CCTAGATCAGAAAAACTGGCCCGAGAGCTCCTTAAAGAGCTGCGAACTCAAGTCTAG
  
  Clone variation with respect to NM_000136.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000136 unedited
  TTCCTTCAGTCCTGGAAGGCTGCTGTGAAGGAATCACCTTTTCGCTTTTTCCAAGATGGC
  TCAAGATTCAGTAGAACTTTCTTGTGATTATCAGTTTTGGATGCAGAAGCTTTCTGTATT
  GGGATCAGGCTTCCACTTTGGAAACCCAGCAAGACACCTGTCTTCACGTGGCTCAGTTCC
  AGGAGTTCCTAAGGAAGATGTATGAAGCCTTGAAAGAGATGGATTCTAATACAGTCATTG
  AAAGATTCCCCACAATTGGTCAACTGTTGGCAAAAGCTTGTTGGAATCCTTTTATTTTAG
  CATATGATGAAAGCCAAAAAATTCTAATATGGTGCTTATGTTGTCTAATTAACAAAGAAC
  CACAGAATTCTGGACAATCAAAACTTAACTCCTGGATACAGGGTGTATTATCTCATATAC
  TTTCAGCACTCAGATTTGATAAAGAAGTTGCTCTTTTCACTCAAGGTCTTGGGTATGCAC
  CTATAGATTACTATCCTGGTTTGCTTAAAAATATGGTTTTATCATTAGCGTCTGAACTCA
  GAGAGAATCATCTTAATGGATTTAACACTCAAAGGCGAATGGCTCCCGAGCGAGTGGCGT
  CCCTGTCACGAGTTTGTGTCCCACTTATTACCCTGACAGATGTTGACCCCCTGGTGGAGG
  CTCTCCTCATCTGTCATGGACGTGAACCTCANGAAATCCTCCAGCCAGAGTTCTTTGAGG
  CTGTAAACGAGGCCATTTTGCTGAAGAAATTTCTCTCCCCATGTCAGCTGTAGTCTGCCT
  CTGGCTTCGGCACCTTCCCAGCCTTGAAAAAGCATGCTGCATCTTTTTGAAAGCTAATCT
  CCAGTGAGAGAAATTGTCTGAGT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000136 unedited
  TGAACCGCGGGCCGCAATCTAGNATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTTTTTAAAAAAAATAGGGTATTGCCATGTTAACCAGGCAGTC
  TGGAACTCCTGGGCTGAAGTAATCCCCCTGCCTTGGCCTCCCAAAGGGCTGGGATCACAG
  GGGGGAGCCACTGGACCCAGCCAGGCCAATTTTTTATCAGGAATTTCCAATTCCCATTTC
  CATTTAACAAGAAAACTAACTAACTGAATTAATCCTGCCTTTTAATGGTTTTGGAACACA
  TTCTTTACCTTCGCCTGGCGGGTTCTTTGATGTCCCAAGGGCCTTTTGGTAGCAGTTAGC
  ATCATTTAACAAATACAAAGTGGAAAAAGTGTGCCGGAGGCCCGGGCTTGGGGGGGCTGT
  CTGCTCCTGGGGCCCGGCAGGCAGGTCCAGGGAAACACAAGGGAAGCCTGAGGGACCCTG
  ACTCCCCTTGAAAAATTTCTCCATACAGCAAGACAGGGGGGCTTTATCCCAAATCCCTGA
  CTCCTAAAAAAAGTCTAAAAAGAGCTAAGTTCTCTCTAAATTCTTTAATGGGTCATGACC
  AAATTCTTGGTTCTAAGACTTTGAATTTTTAAATAATAGATGTGCAGCTTGACTTGGGTA
  AAAACTAAAAACCTGTTCTCCCACCCAAGCCTTTGCTTTAATAATTATTAAACTGACCGT
  CTTGCCCGGCGGGCCCCAAAAGACCCCAAGCTCCCTTGAGTATTAAGGAACATGTCTGCC
  TGAGTCTGGGCCTGAGGACCCGGCTTCTCCTTTTTGAAAAAAGAAACCAGCAAAATGGCC
  CAAGAGGTTTCAGTTTATTTTTACAGCCCAGGAGGGCCTTATCCCAAAAAGGCGGGCCCC
  AGGGAATACCGTGCTTGGGCCTGGAG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_000136
• Insert Size: 2710 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000136.2, NP_000127.2
• RefSeq Size: 4612 bp
• RefSeq ORF: 1677 bp
• Locus ID: 2176
• Cytogenetics: 9q22.32
• Domains: Fanconi
• Protein Families: Druggable Genome
• Gene Summary: 'The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group C. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a).