glucose 6 phosphatase, catalytic subunit (G6PC) (NM_000151) Human Untagged Clone

CAT#: SC120076

G6PC (untagged)-Human glucose-6-phosphatase, catalytic subunit (G6PC)


  "NM_000151" in other vectors (6)

Reconstitution Protocol

USD 760.00

In Stock*

Size
    • 10 ug

Product Images

Other products for "G6PC"

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol G6PC
Synonyms G6Pase; G6PC1; G6PT; GSD1; GSD1a
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC120076 sequence for NM_000151 edited (data generated by NextGen Sequencing)
ATGGAGGAAGGAATGAATGTTCTCCATGACTTTGGGATCCAGTCAACACATTACCTCCAG
GTGAATTACCAAGACTCCCAGGACTGGTTCATCTTGGTGTCCGTGATCGCAGACCTCAGG
AATGCCTTCTACGTCCTCTTCCCCATCTGGTTCCATCTTCAGGAAGCTGTGGGCATTAAA
CTCCTTTGGGTAGCTGTGATTGGAGACTGGCTCAACCTCGTCTTTAAGTGGATTCTCTTT
GGACAGCGTCCATACTGGTGGGTTTTGGATACTGACTACTACAGCAACACTTCCGTGCCC
CTGATAAAGCAGTTCCCTGTAACCTGTGAGACTGGACCAGGGAGCCCCTCTGGCCATGCC
ATGGGCACAGCAGGTGTATACTACGTGATGGTCACATCTACTCTTTCCATCTTTCAGGGA
AAGATAAAGCCGACCTACAGATTTTGGTGCTTGAATGTCATTTTGTGGTTGGGATTCTGG
GCTGTGCAGCTGAATGTCTGTCTGTCACGAATCTACCTTGCTGCTCATTTTCCTCATCAA
GTTGTTGCTGGAGTCCTGTCAGGCATTGCTGTTGCAGAAACTTTCAGCCACATCCACAGC
ATCTATAATGCCAGCCTCAAGAAATATTTTCTCATTACCTTCTTCCTGTTCAGCTTCGCC
ATCGGATTTTATCTGCTGCTCAAGGGACTGGGTGTAGACCTCCTGTGGACTCTGGAGAAA
GCCCAGAGGTGGTGCGAGCAGCCAGAATGGGTCCACATTGACACCACACCCTTTGCCAGC
CTCCTCAAGAACCTGGGCACGCTCTTTGGCCTGGGGCTGGCTCTCAACTCCAGCATGTAC
AGGGAGAGCTGCAAGGGGAAACTCAGCAAGTGGCTCCCATTCCGCCTCAGCTCTATTGTA
GCCTCCCTCGTCCTCCTGCACGTCTTTGACTCCTTGAAACCCCCATCCCAAGTCGAGCTG
GTCTTCTACGTCTTGTCCTTCTGCAAGAGTGCGGTAGTGCCCCTGGCATCCGTCAGTGTC
ATCCCCTACTGCCTCGCCCAGGTCCTGGGCCAGCCGCACAAGAAGTCGTTGTAA

Clone variation with respect to NM_000151.2
445 c=>t;574 a=>g
>OriGene 5' read for NM_000151 unedited
GCATATGTATACGACTCACTATAGGGCGGCCGCGAATTCGGCACCAGACCACCAAGCCTG
GATAACTGCAGGGCTCTGCTGACATCTTCCTGAGGTGCCAAGGAAATGAGGATGGAGGAA
GGAATGAATGTTCTCCATGACTTTGGGATCCAGTCAACACATTACCTCCAGGTGAATTAC
CAAGACTCCCAGGACTGGTTCATCTTGGTGTCCGTGATCGCAGACCTCAGGAATGCCTTC
TACGTCCTCTTCCCCATCTGGTTCCATCTTCAGGAAGCTGTGGGCATTAAACTCCTTTGG
GTAGCTGTGATTGGAGACTGGCTCAACCTCGTCTTTAAGTGGATTCTCTTTGGACAGCGT
CCATACTGGTGGGTTTTGGATACTGACTACTACAGCAACACTTCCGTGCCCCTGATAAAG
CAGTTCCCTGTAACCTGTGAGACTGGACCAGGGAGCCCCTCTGGCCATGCCATGGGCACA
GCAGGTGTATACTACGTGATGGTCACATCTACTCTTTCCATCTTTCAGGGAAAGATAAAG
CCGACCTACAGATTTTGGTGCTTGAATGTCATTTTGTGGTTGGGATTCTGGGCTGTGCAG
CTGAATGTCTGTCTGTCACGAATCTACCTTGCTGCTCATTNTCCTCATCAAGTTGTTGCT
GGAGTCCTGTCAGGCATTGCTGTTGCAGAAACTTTCAGCCACATCCACAGCATCTATAAT
GCCAGCCTCAAGAAATATTTCTCATTACCTTNCTCCTGTTCAGCTTCGCCATCGGATTNT
ATCTGCTGCTCAGGGACTGGGTGTAGACCTCCTGTGGACTCTGCAGAAAGCCCCCAGTGG
TGCGAGCAGCCAGAATGGGTCCCATTGACACACACCTTTGCCAGCCCCTCAAGACCTGGC
ACGCTCTTTGCCTGGGCCTGCTCTCACTCCCCTGTCAAGGAGAGCGCAGGNGAACTA
>OriGene 3' read for NM_000151 unedited
AGTTTGGCCGCGGCCGCAATCNANAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTATAGGAATTAACAAGACGTGATTCTTAAATAAAATGTTGCTTTAATAAAATACT
GCACATATATATTTTTCTTTTCAAAGATGTTATGAGCAGGATGGTTGTTTTGAATGATAA
TGTATGGTATACTATATAATTAGTAGCAAAAACAAGGACTTTCAAATAAATAGGCTTCAT
CTTTTTTTGGGGGGTAGGTGGGTGGGGCAAAAATACTCTGCATATCAGATGAAATTGAAA
AACAGGCAAGGAGGGCCCGGTGCGGGGGCTCATGCCTGTAATCCTAGCACCTTGGGAGGC
CAAGGCAGGTGGATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGATGAAA
TCCCATCTCTTCTAAAAATATAAAAATTAGCCTGGCATGGTGGTGCACGCCGGTAGTCCT
AGCTACTGAGGAGGCTGAGACATGAGAATCGCTTGAACCAGGAGGAAGAGGTTGCAGTGA
GCCAAGATCGTGCCACTCCACTCCAGCCTGGGTGATAGGTGCGCCGTCTCAAAAAAAGAA
AAAAAAAGAAAAGCAGGCAAGGAGGAGTTGGCTAGCTGGACATAGTGGCTTGCACCTGTA
GTCCCAGCTACGCGGGACGCTGTGGTATGGTGGGAGGACTGCTTGAGCCCANGAATTCAG
AGCAGCCTGGGCAACATAGTGAGACCCTGTCTCAAAAAAAAAAAAAAGAGAGAGAATGTG
ACTTTTCCTTTAAAATGTGCTCTTGGNTGGCCTTGGGATAAAGAAAGGATTCTATTTTAC
CCTCTAGGAATAAAAGTTACACTGGAATGACCTGAAAAAGGATTCTGGNCCTCCCCTTGA
ATTTTGCCAACAATTCAGACCCTATTGGAACTACAAAGCCCCACGGGTCGCCTCTAGCT
Restriction Sites NotI-NotI     
ACCN NM_000151
Insert Size 3110 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_000151.1, NP_000142.1
RefSeq Size 3095 bp
RefSeq ORF 1074 bp
Locus ID 2538
Cytogenetics 17q21.31
Domains acidPPc
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Adipocytokine signaling pathway, Galactose metabolism, Glycolysis / Gluconeogenesis, Insulin signaling pathway, Metabolic pathways, Starch and sucrose metabolism
Gene Summary 'Glucose-6-phosphatase (G6Pase) is a multi-subunit integral membrane protein of the endoplasmic reticulum that is composed of a catalytic subunit and transporters for G6P, inorganic phosphate, and glucose. This gene (G6PC) is one of the three glucose-6-phosphatase catalytic-subunit-encoding genes in human: G6PC, G6PC2 and G6PC3. Glucose-6-phosphatase catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate and is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Mutations in this gene cause glycogen storage disease type I (GSD1). This disease, also known as von Gierke disease, is a metabolic disorder characterized by severe hypoglycemia associated with the accumulation of glycogen and fat in the liver and kidneys.[provided by RefSeq, Feb 2011]'
Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

Other Versions

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.