CDC2L1 (CDK11B) (NM_033490) Human Untagged Clone

CAT#: SC120103

CDC2L1 (untagged)-Human cell division cycle 2-like 1 (PITSLRE proteins) (CDC2L1), transcript variant 6

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CDK11B
• Synonyms: CDC2L1; CDK11; CDK11-p46; CDK11-p58; CDK11-p110; CLK-1; p58; p58CDC2L1; p58CLK-1; PITSLREA; PK58
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_033490 edited
  GCGTGTACGGTGGGAGGTCTATATAAGCAGAGCTCATTTAGGTGACACTATAGAATACAA
  GCTACTTGTTCTTTTTGCAGCGGCCGCGAATTCGGCACGAGGAGAAGGAGCGCGAGCGGC
  GGGCAGAGGAGCGGCGCAAGGAGCGGGAGGCCCGCAGGGAAGTGTCTGCACATCACCGAA
  CGATGAGAGAGGACTACAGCGACAAAGTGAAAGCCAGCCACTGGAGTCGCAGCCCGCCTC
  GGCCGCCGCGGGAGCGGTTCGAGTTGGGAGACGGCCGGAAGCCAGTAAAAGAAGAGAAAA
  TGGAAGAAAGGGACCTGCTGTCCGACTTACAGGACATCAGCGACAGCGAGAGGAAGACCA
  GCTCGGCCGAGTCCTCGTCAGCGGAATCAGGCTCAGGTTCTGAGGAAGAAGAGGAGGAGG
  AGGAAGAGGAGGAGGAGGAAGGGAGCACCAGTGAAGAATCAGAGGAGGAGGAGGAGGAAG
  AGGAAGAGGAGGAGGAGGAGACCGGCAGCAACTCTGAGGAGGCATCAGAGCAGTCTGCCG
  AAGAAGTAAGTGAGGAAGAAATGAGTGAAGATGAAGAACGAGAAAATGAAAACCACCTCT
  TGGTTGTTCCAGAGTCACGGTTCGACCGAGATTCCGGGGAGAGTGAAGAAGCAGAGGAAG
  AAGTGGGTGAGGGAACGCCGCAGAGCAGCGCCCTGACAGAGGGCGACTATGTGCCCGACT
  CCCCTGCCCTGTCGCCCATCGAGCTCAAGCAGGAGCTGCCCAAGTACCTGCCGGCCCTGC
  AGGGCTGCCGGAGCGTCGAGGAGTTCCAGTGCCTGAACAGGATCGAGGAGGGCACCTATG
  GAGTGGTCTACAGAGCAAAAGACAAGAAAACAGATGAAATTGTGGCTCTAAAGCGGCTGA
  AGATGGAGAAGGAGAAGGAGGGCTTCCCGATCACGTCGCTGAGGGAGATCAACACCATCC
  TCAAGGCCCAGCATCCCAACATCGTCACCGTTAGAGAGATTGTGGTGGGCAGCAACATGG
  ACAAGATCTACATCGTGATGAACTATGTGGAGCACGACCTCAAGAGCCTGATGGAGACCA
  TGAAACAGCCCTTCCTGCCAGGGGAGGTGAAGACCCTGATGATCCAGCTGCTGCGTGGGG
  TGAAACACCTGCACGACAACTGGATCCTGCACCGTGACCTCAAGACGTCCAACCTGCTGC
  TGAGCCACGCCGGCATCCTCAAGGTGGGTGACTTCGGGCTGGCGCGGGAGTACGGATCCC
  CTCTGAAGGCCTACACCCCGGTCGTGGTGACCCTGTGGTACCGCGCCCCAGAGCTGCTGC
  TTGGTGCCAAGGAATACTCCACGGCCGTGGACATGTGGTCAGTGGGTTGCATCTTCGGGG
  AGCTGCTGACTCAGAAGCCTCTGTTCCCCGGGAAGTCAGAAATCGATCAGATCAACAAGG
  TGTTCAAGGATCTGGGGACCCCTAGTGAGAAAATCTGGCCCGGCTACAGCGAGCTCCCAG
  CAGTCAAGAAGATGACCTTCAGCGAGCACCCCTACAACAACCTCCGCAAGCGCTTCGGGG
  CTCTGCTCTCAGACCAGGGCTTCGACCTCATGAACAAGTTCCTGACCTACTTCCCCGGGA
  GGAGGATCAGCGCTGAGGACGGCCTCAAGCATGAGTATTTCCGCGAGACCCCCCTCCCCA
  TCGACCCCTCCATGTTCCCCACGTGGCCCGCCAAGAGCGAGCAGCAGCGTGTGAAGCGGG
  GCACCAGCCCGAGGCCCCCTGAGGGAGGCCTGGGCTACAGCCAGCTGGGTGACGACGACC
  TGAAGGAGACGGGCTTCCACCTTACCACCACGAACCAGGGGGCCTCTGCCGCGGGCCCCG
  GCTTCAGCCTCAAGTTCTGAAGGTCAGAGTGGACCCCGTCATGGGGAGAACTCAGCCGGG
  ACCACAGGCGTGGCTACTGCGGCTGGAGCTGCGATGAGACTCGGAACTCCTCGTCTTACT
  TTGTGCTCCATGTTTTGTTTTTGTATTTTGGTTTGTAAATTTGTAGAATTAAATCATTTT
  CCTTGTTGTGGAGGAAAGAGCTGTGTTTTCTCCGTGACTTGCCCAGGGCGGAGAGGGTGG
  GCATCTTCGGGTGCCCACGTGGGGCAGCACAAACCTCCACACACCCTCTCCCACTCTCGA
  CACGCACGGGGCTGGCTGGGCCGTGATTTGGAAAGGAACTGGTGGGAGCCGGGTGGATTG
  TTTAATCTTCGGAGCTGGAGACCTGTTTCTGTGTTGGGATGAGCGATGCCCTCTTGCCCC
  AACCCACTCGTCCAGACCAGCCCTGTCCACACAGGCCCCCGGCCCCCAACCCCCAGCCCC
  AGCTGTGCCAGCAGACTCGACAGGTTTTTATACAAGGTTGTTGAGTTTTAAAATGTATTA
  AAATATTCTTCGAGAAAAAAAAAAAAAAAAAACTCGACTCTAGATTGCGGCCGCGGTCAT
  AGCTGTTTCCTGAACAGATCCCGGGTGGCATCCCTGTGACCCCTCCCCAGTGCCT
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_033490 unedited
  GAGGGGNGGGAGGAAANANNNNNNNNTNTNNNNNNNATTTCTTACACCCGCCCGTTGNCG
  CAAAGGGCGGTAGGCGTGTACGGTGGGNAGTCTATATAAGCAGAGCTCATTTAGGTGACA
  CTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGCGAATTCGGCACGAGGAGAAG
  GAGCGCGAGCGGCGGGCAGAGGAGCGGCGCAAGGAGCGGGAGGCCCGCAGGGAAGTGTCT
  GCACATCACCGAACGATGAGAGAGGACTACAGCGACAAAGTGAAAGCCAGCCACTGGAGT
  CGCAGCCCGCCTCGGCCGCCGCGGGAGCGGTTCGAGTTGGGAGACGGCCGGAAGCCAGTA
  AAAGAAGAGAAAATGGAAGAAAGGGACCTGCTGTCCGACTTACAGGACATCAGCGACAGC
  GAGAGGAAGACCAGCTCGGCCGAGTCCTCGTCAGCGGAATCAGGCTCAGGTTCTGAGGAA
  GAAGAGGAGGAGGAGGAAGAGGAGGANGNNGAANGNNNNNCANNGAANAANAAAGGAGGA
  GGAGGAGGAANAGGAANANAAAAAAAAAAAAGAAGAAAGGGGGAAAGAGAAAAAAAAAGA
  AGAAAAAANAAGGAAGAAGAGGAGCCGAGAGAAAAAGAGAAGAAAAAAAAGAAAAAGAAA
  AAAAAAAAAAGAAGAANAAAGAAAGAANAAAGAAAAAAAGAAAAGGCCGAGAAGGAAGGA
  AGAAAAAGAAAAAANAGAGGAGGGAAAGGACCAACCANNAGCANAAAAAGACGAGACCCC
  ACCCCCCCCNCGCCCCCCGCAGCACCCCCACCCACCACGCCACCCACCCCCAAACAGACA
  CCGCCACCCCCCGCCGCGCCACCCCCCAGACCGGCCCGAGAACACCCACACACGCCAACC
  CCCCAGCCCCCCCCCCCCCGCCCGCCGCCCCCCCCACACCCCGGCCCCCGCGCCACACGC
  AGACCCCCCCCCCCACCG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_033490 unedited
  CATCCGATGTACGCGGCCGCNCTCNANGATCGAGTTTTTTTTTTTTTTTTTTCTCGAAGA
  ATATTTTAATACATTTTAAAACTCAACAACCTTGTATAAAAACCTGTCGAGTCTGCTGGC
  ACAGCTGGGGCTGGGGGTTGGGGGCCGGGGGCCTGTGTGGACAGGGCTGGTCTGGACGAG
  TGGGTTGGGGCAAGAGGGCATCGCTCATCCCAACACAGAAACAGGTCTCCAGCTCCGAAG
  ATTAAACAATCCACCCGGCTCCCACCAGTTCCTTTCCAAATCACGGCCCAGCCAGCCCCG
  TGCGTGTCGAGAGTGGGAGAGGGTGTGTGGAGGTTTGTGCTGCCCCACGTGGGCACCCGA
  AGATGCCCACCCTCTCCGCCCTGGGCAAGTCACGGAGAAAACACAGCTCTTTCCTCCACA
  ACAAGGAAAATGATTTAATTCTACAAATTTACAAACCAAAATACAAAAACAAAACATGGA
  GCACAAAGTAAGACGAGGAGTTCCGAGTCTCATCGCAGCTCCAGCCGCAGTAGCCACGCC
  TGTGGTCCCGGCTGAGTTCTCCCCATGACGGGGTCCACTCTGACCTTCAGAACTTGAGGC
  TGAAGCCGGGGCCCGCGGCAGATGCCCCCTGGTTCGTGGTGGTAAGGTGGAAGCCCGTCT
  CCTTCAAGTCGTCGTCACCCAGCTGGCTGTAGCCCAGGCCTCCCTCAGGGAGCCTCGGGC
  TGGTGCCCCGCTTACACGCTGCTGCTCGCTCTTGGCGGGCACGTGGGGAACATGGAGGGG
  TCNATGGGGAGGGGGGGCTCGCGGAAATACTCATGCTGAGGGCGTCCTCAACGCTGATCC
  TCTCCCGGGGAATTAGTTAAGGACTTGTCATGAGGTCAAAACCTGTTTGAAACC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_033490
• Insert Size: 2500 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_033490.1, NP_277025.1
• RefSeq Size: 2349 bp
• RefSeq ORF: 1698 bp
• Locus ID: 984
• Cytogenetics: 1p36.33
• Domains: pkinase, TyrKc, S_TKc
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: 'This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]'
  Transcript Variant: This variant (6) differs in its 5' UTR, uses a downstream start codon, and uses an alternate splice site in its 5' coding region, compared to variant 1. The encoded isoform (6) is shorter, compared to isoform 1.