ANKH (NM_054027) Human Untagged Clone

CAT#: SC120218

ANKH (untagged)-Human ankylosis, progressive homolog (mouse) (ANKH)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ANKH
• Synonyms: ANK; CCAL2; CMDJ; CPPDD; HANK; MANK; SLC62A1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC120218 sequence for NM_054027 edited (data generated by NextGen Sequencing)
  ATGGTGAAATTCCCGGCGCTCACGCACTACTGGCCCCTGATCCGGTTCTTGGTGCCCCTG
  GGCATCACCAACATAGCCATCGACTTCGGGGAGCAGGCCTTGAACCGGGGCATTGCTGCT
  GTCAAGGAGGATGCAGTCGAGATGCTGGCCAGCTACGGGCTGGCGTACTCCCTCATGAAG
  TTCTTCACGGGTCCCATGAGTGACTTCAAAAATGTGGGCCTGGTGTTTGTGAACAGCAAG
  AGAGACAGGACCAAAGCCGTCCTGTGTATGGTGGTGGCAGGGGCCATCGCTGCCGTCTTT
  CACACACTGATAGCTTATAGTGATTTAGGATACTACATTATCAATAAACTGCACCATGTG
  GACGAGTCGGTGGGGAGCAAGACGAGAAGGGCCTTCCTGTACCTCGCCGCCTTTCCTTTC
  ATGGACGCAATGGCATGGACCCATGCTGGCATTCTCTTAAAACACAAATACAGTTTCCTG
  GTGGGATGTGCCTCAATCTCAGATGTCATAGCTCAGGTTGTTTTTGTAGCCATTTTGCTT
  CACAGTCACCTGGAATGCCGGGAGCCCCTGCTCATCCCGATCCTCTCCTTGTACATGGGC
  GCACTTGTGCGCTGCACCACCCTGTGCCTGGGCTACTACAAGAACATTCACGACATCATC
  CCTGACAGAAGTGGCCCGGAGCTGGGGGGAGATGCAACAATAAGAAAGATGCTGAGCTTC
  TGGTGGCCTTTGGCTCTAATTCTGGCCACACAGAGAATCAGTCGGCCTATTGTCAACCTC
  TTTGTTTCCCGGGACCTTGGTGGCAGTTCTGCAGCCACAGAGGCAGTGGCGATTTTGACA
  GCCACATACCCTGTGGGTCACATGCCATACGGCTGGTTGACGGAAATCCGTGCTGTGTAT
  CCTGCTTTCGACAAGAATAACCCCAGCAACAAACTGGTGAGCACGAGCAACACAGTCACG
  GCAGCCCACATCAAGAAGTTCACCTTCGTCTGCATGGCTCTGTCACTCACGCTCTGTTTC
  GTGATGTTTTGGACACCCAACGTGTCTGAGAAAATCTTGATAGACATCATCGGAGTGGAC
  TTTGCCTTTGCAGAACTCTGTGTTGTTCCTTTGCGGATCTTCTCCTTCTTCCCAGTTCCA
  GTCACAGTGAGGGCGCATCTCACCGGGTGGCTGATGACACTGAAGAAAACCTTCGTCCTT
  GCCCCCAGCTCTGTGCTGCGGATCATCGTCCTCATCGCCAGCCTCGTGGTCCTACCCTAC
  CTGGGGGTGCACGGTGCGACCCTGGGCGTGGGCTCCCTCCTGGCGGGCTTTGTGGGAGAA
  TCCACCATGGTCGCCATCGCTGCGTGCTATGTCTACCGGAAGCAGAAAAAGAAGATGGAG
  AATGAGTCGGCCACGGAGGGGGAAGACTCTGCCATGACAGACATGCCTCCGACAGAGGAG
  GTGACAGACATCGTGGAAATGAGAGAGGAGAATGAATAA
  
  Clone variation with respect to NM_054027.4
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_054027 unedited
  NGGTCACATTTGTAAACGATCACTATAGGCGGCCGCGAATTCGCACGAGGCGCTTATAAT
  GGAGCCGCTGTCAGCAGAACCTTCTGCCGCCGCCGCCGCCGCCGCCGTCCCTCCTCTTTT
  TTTTCCCGGCAGATCTTTGTTGTGTGGGAGGGCAGCAGGGATGGACTTGAGCTTGCGGAT
  CCCCTGCTAGAGCAGCCGCGCTCGGAGAAGGCGCCGCAGCCGCGAGGAGGAGCCGCCGCC
  GCCGCGCCCGAGGCCCCGCCGCCCGCGGCCTCTGTCGGCCCGCGCCCCGCTCGCCCCGTC
  GCCCCGTCGCCCCTCGCCTCCCCGCAGAGTCCCCTCGCGGCAGCAGATGTGTGTGGGGTC
  AGCCCACGGCGGGGACTATGGTGAAATTCCCGGCGCTCACGCACTACTGGCCCCTGATCC
  GGTTCTTGGTGCCCCTGGGCATCACCAACATAGCCATCGACTTCGGGGAGCAGGCCTTGA
  ACCGGGGCATTGCTGCTGTCAAGGAGGATGCAGTCGAGATGCTGGCCAGCTACGGGCTGG
  CGTACTCCCTCATGAAGTTCTTCACGGGTCCCATGAGTGACTTCAAAAATGTGGGCCTGG
  TGTTTGTGAACAGCAAGAGAGACAGGACCAAAGCCGTCCTGTGTATGGTGGTGGCAGGGG
  CCATCGCTGCCGTCTTTCACACACTGATAGCTTATAGTGATTTAGGATACTACATTATCA
  ATAAACTGCACCATGTGGACGAGTNCGTGGGGAGCAAGACGAGAAGGGCCTTCCTGTACC
  TCGCCGCCTTTCCTTCATGGNACGCATGGCATGGACCCATGCTGGCATTCTCTTAAACAC
  AAATACAGGTTCCTGGTGGGGATGTGCCCTCATCTCAGATGTCATAGCTCAAGGTGTTTT
  TGTAGCCTTTTGCTNACAGTCACCTGAATGCCGGNAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_054027 unedited
  TTTGGCCGAGGCCGCNGTCNATGGCGAGTTAAATTCCTTTTTTTTTGGATTAGAGACATT
  TTATTGAAAATGCGAAAATAGGAAATGTATTATAGCCTAAAATAAATTACATAACATATA
  CAGCATATATTTATATCTTTAAAATATTTTTTTGTTTAGGTTCTTTCAGTCTAGGAATTC
  TGACTAAATCAATTTAGTGAACCGTGTCTATAATTTTTTTAAAGGAAAAAACCTGCTTTC
  CAAAACTTAGAAAAATATACTGCACTGCATGGATTTCGAATGCGTTATTTCAGGGAGGAC
  CACATAGTGACTCTGGTATCGTTATAAAATGTCTTGCTTTATCGTATGGTGTGGGAGGGA
  AGTACCGTAGTACATTCTCAATTACCTGTACCGCACAGTTATGACTAAGGATAGCAGAAC
  CAGGTAATATATCTACTTCAAAAGTTACCCTACAGCAACCTGGCATTAGAATGCTGGATG
  AGACTTAAAGCTTCAGTTCACTGTAAAAACTAAAATGCAAAGCTAGGATGCTCCATGTGA
  CTCGCTCTAATGCGACCTTCAGGAAAGGCGAGGGAAAAGCAAGCCTTCAGGAAAAGTAAT
  GCGGCAGGGTCTGGAATCTGGAGATGCGCTCTTTGTGACAATTCAAAAAAGTTAGCTCAT
  GCATATACACCGTGGGGGTGAGAACTGACAGCTCGCTCAGATCTAGGAGAACGCCAGAGT
  GAAATGCTATCATTTAACCCTGTCAGCCTGCTGCACTCGGGGTATTTAAAACCAAACCCT
  TCTACGGAAGATTCTGGACATCCGATACACTGCTGGGGCACAAGACCTGCGTTCTCAAGT
  GAACCGGGACCTCGGGCTGGAACGTGTCACACGCCTCCCGNTCGGGTGGGAAAAAGGGTT
  ACAACTCCCTGGCGGAAGGGAATATTAAAAGCTCCCCGCGNCTACATTCTTTGTTCGCGC
  CTGTGACGGGAAGCCAATCAAGGAACCCGATT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_054027
• ORF Size: 1479 bp
• Insert Size: 3370
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_054027.3, NP_473368.1
• RefSeq Size: 4086
• RefSeq ORF: 1479
• Locus ID: 56172
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: This gene encodes a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. Progressive ankylosis-mediated control of pyrophosphate levels has been suggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals. Mutations in this gene have been associated with autosomal dominant craniometaphyseal dysplasia. [provided by RefSeq, Jul 2008]