Cyclin E2 (CCNE2) (NM_057749) Human Untagged Clone

CAT#: SC120236

CCNE2 (untagged)-Human cyclin E2 (CCNE2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CCNE2
• Synonyms: CYCE2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC120236 sequence for NM_057749 edited (data generated by NextGen Sequencing)
  ATGTCAAGACGAAGTAGCCGTTTACAAGCTAAGCAGCAGCCCCAGCCCAGCCAGACGGAA
  TCCCCCCAAGAAGCCCAGATAATCCAGGCCAAGAAGAGGAAAACTACCCAGGATGTCAAA
  AAAAGAAGAGAGGAGGTCACCAAGAAACATCAGTATGAAATTAGGAATTGTTGGCCACCT
  GTATTATCTGGGGGGATCAGTCCTTGCATTATCATTGAAACACCTCACAAAGAAATAGGA
  ACAAGTGATTTCTCCAGATTTACAAATTACAGATTTAAAAATCTTTTTATTAATCCTTCA
  CCTTTGCCTGATTTAAGCTGGGGATGTTCAAAAGAAGTCTGGCTAAACATGTTAAAAAAG
  GAGAGCAGATATGTTCATGACAAACATTTTGAAGTTCTGCATTCTGACTTGGAACCACAG
  ATGAGGTCCATACTTCTAGACTGGCTTTTAGAGGTATGTGAAGTATACACACTTCATAGG
  GAAACATTTTATCTTGCACAAGACTTTTTTGATAGATTTATGTTGACACAAAAGGATATA
  AATAAAAATATGCTTCAACTCATTGGAATTACCTCATTATTCATTGCTTCCAAACTTGAG
  GAAATCTATGCTCCTAAACTCCAAGAGTTTGCTTACGTCACTGATGGTGCTTGCAGTGAA
  GAGGATATCTTAAGGATGGAACTCATTATATTAAAGGCTTTAAAATGGGAACTTTGTCCT
  GTAACAATCATCTCCTGGCTAAATCTCTTTCTCCAAGTTGATGCTCTTAAAGATGCTCCT
  AAAGTTCTTCTACCTCAGTATTCTCAGGAAACATTCATTCAAATAGCTCAGCTTTTAGAT
  CTGTGTATTCTAGCCATTGATTCATTAGAGTTCCAGTACAGAATACTGACTGCTGCTGCC
  TTGTGCCATTTTACCTCCATTGAAGTGGTTAAGAAAGCCTCAGGTTTGGAGTGGGACAGT
  ATTTCAGAATGTGTAGATTGGATGGTACCTTTTGTCAATGTAGTAAAAAGTACTAGTCCA
  GTGAAGCTGAAGACTTTTAAGAAGATTCCTATGGAAGACAGACATAATATCCAGACACAT
  ACAAACTATTTGGCTATGCTGGAGGAAGTAAATTACATAAACACCTTCAGAAAAGGGGGA
  CAGTTGTCACCAGTGTGCAATGGAGGCATTATGACACCACCGAAGAGCACTGAAAAACCA
  CCAGGAAAACACTAA
  
  Clone variation with respect to NM_057749.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_057749 unedited
  TGTCAGCATTTGTATACGACTCATATAGGCGGCCTGCGAATCGGCACGAGGGAGGTTTTA
  TACACCTGAAAGAGAGATGTCAAGACGAAGTAGCCGTTTACAAGCTAAGCAGCAGCCCCA
  GCCCAGCCAGACGGAATCCCCCCAAGAAGCCCAGATAATCCAGGCCAAGAAGAGGAAAAC
  TACCCAGGATGTCAAAAAAAGAAGAGAGGAGGTCACCAAGAAACATCAGTATGAAATTAG
  GAATTGTTGGCCACCTGTATTATCTGGGGGGATCAGTCCTTGCATTATCATTGAAACACC
  TCACAAAGAAATAGGAACAAGTGATTTCTCCAGATTTACAAATTACAGATTTAAAAATCT
  TTTTATTAATCCTTCACCTTTGCCTGATTTAAGCTGGGGATGTTCAAAAGAAGTCTGGCT
  AAACATGTTAAAAAAGGAGAGCAGATATGTTCATGACAAACATTTTGAAGTTCTGCATTC
  TGACTTGGAACCACAGATGAGGTCCATACTTCTAGACTGGCTTTTAGAGGTATGTGAAGT
  ATACACACTTCATAGGGAAACATTTTATCTTGCACAAGACTTTTTTGATAGATTTATGTT
  GACACAAAAGGATATAAATAAAAATATGCTTCAACTCATTGGAATTACCTCATTATTCAT
  TGCTTCCAAACTTGAGGAAATCTATGCTCCTAAACTCCAAGAGTTTGCTTACGTCACTGA
  TGGTGCTTGCAGTGAAGAGGATATCTTAAGGATGGAACTCATTATATTAAAGGCTTTACA
  ATGGGAACTNTGTCCTGNTACAATCATCTCCTGGCTAAATCTCTTTCNTCCAGNTGATGC
  TCTTAAAGAGCTCCTACAGTCTTCTACCTCAGTATTCTCAGGAACATTCATTCAATAGCT
  CAGCTTTTA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_057749 unedited
  NNTTTTGCTTTGGAACCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTAAA
  TTTTTTTAACTTTTATTTTTTAAACAATGGGGCTAAAAATAAACAGTATTAAAAGGTTAA
  GTTTATATAATACATATGTACACAATTAGTGGTGTTTTCTTTTCAGACAAAATACTGAAA
  CAAATATTAGTTTAAAAACAAACTATACAGAAGACTTCATACCGTAACAATAAATGTATA
  GTTTCTTCAAAGGGAGAAGAGATTCACATATCTGATAACAAAATAAACTAGCAATCTAGT
  TTTCTAATCTACTTTATGAGGCTGGATTTTTTTTTTAGAAAAGCTAATTTAAAATATTTA
  GAAATAGCTAGCCTATGTACAGCAAGTTTTCATGTCTTTTTTTAATAAATAGATTTCTAG
  GAGTCAGTATATATTTAATACTCTTCTTCCTTAAGAAAATAGAAGTTTAGGTCAAGTGTT
  AAGCTTTATCACTTTGACACTGTCCTTATCTCACAATGGAGGAATTTAGAAAGGACCTTA
  ACAGTTTCACAAACATAAATAAAGCCTTAGTCACACTAAATTAAAAAAAAAATTCCTTAG
  GGATATCTTAGAGTAGTAAAGTGACTTCCTCATATAAATAGTTTGAAAGGGTACTTAAGT
  TTTTCACCCAAATTGTGATATACAAAAAGGTTATTACCAAGCAACCTACATGTCAAGAAA
  GCCCCAGTTAGGAAGGAGCCACAGCATTTATCTTGTTTATAATTTCTTTGGGACTCCCAC
  TGTTTAGAGCACAGGTTGAACACCATGTTCATCTAAGCCTTATTAGTTAAAAAATGTGTT
  ATGGGCAAGGCAATAAACTAGTTTAAAAACATTAAATTCACCATTTGTAGAATTCAAGTT
  TATAATAGCTTGCTTAGCAGCATAGATAAAT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_057749
• ORF Size: 1215 bp
• Insert Size: 2960
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_057749.1, NP_477097.1
• RefSeq Size: 2748
• RefSeq ORF: 1215
• Locus ID: 9134
• Domains: cyclin_C, CYCLIN, cyclin
• Protein Families: Druggable Genome
• Protein Pathways: Cell cycle, Oocyte meiosis, p53 signaling pathway, Pathways in cancer, Prostate cancer, Small cell lung cancer
• Gene Summary: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells. [provided by RefSeq, Jul 2008]