PIK3C2G (NM_004570) Human Untagged Clone

CAT#: SC120317

PIK3C2G (untagged)-Human phosphoinositide-3-kinase, class 2, gamma polypeptide (PIK3C2G)


  "NM_004570" in other vectors (4)

Reconstitution Protocol

USD 1,100.00

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol PIK3C2G
Synonyms PI3K-C2-gamma; PI3K-C2GAMMA
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF sequence for NM_004570 edited
GAGATCGTGTTTCATTTCAGGAAGATATATGCGTCAGGAAAATTTCTATCTTCTTTTGTA
TTATCAAGGAGATATTTGGAGCAGAGTCAACCCTCTCAGTTACATAAAATAAAAAATGGC
ATATTCTTGGCAAACGGATCCAAATCCTAATGAATCACACGAAAAGCAGTATGAACACCA
AGAATTTCTCTTTGTAAATCAACCCCATTCTTCTAGCCAAGTCAGTCTGGGTTTTGATCA
GATAGTAGATGAGATCAGTGGCAAAATTCCACACTACGAGAGTGAAATTGATGAAAACAC
CTTTTTTGTGCCCACTGCACCAAAATGGGACTCAACAGGGCATTCATTAAATGAAGCACA
CCAAATATCCTTGAATGAATTCACTTCTAAAAGCCGTGAACTCTCCTGGCATCAAGTTAG
CAAAGCACCAGCAATTGGTTTTAGTCCTTCTGTGTTACCAAAACCTCAAAATACGAATAA
AGAATGCTCCTGGGGAAGCCCCATAGGAAAACATCATGGTGCTGATGATTCCAGATTCAG
TATTTTAGCTCTATCATTCACAAGTTTGGATAAAATTAATCTAGAGAAAGAATTAGAAAA
TGAAAATCATAACTACCATATAGGATTTGAAAGTAGCATTCCTCCAACAAATTCATCCTT
CTCAAGTGACTTCATGCCGAAAGAAGAGAATAAAAGGAGTGGACATGTGAACATTGTGGA
ACCATCTTTGATGCTTTTGAAAGGCTCTCTTCAACCCGGAATGTGGGAAAGTACATGGCA
GAAGAATATAGAGTCAATAGGTTGTTCCATTCAGCTAGTGGAAGTACCTCAAAGCAGCAA
TACGAGTCTGGCCTCTTTTTGCAACAAAGTAAAAAAAATCAGAGAAAGATATCATGCAGC
TGATGTTAATTTCAATTCTGGGAAGATCTGGAGCACTACTACAGCATTTCCGTATCAGCT
CTTTTCTAAGACCAAGTTTAATATACATATTTTTATTGATAACTCAACACAACCTCTTCA
TTTTATGCCATGTGCTAATTATCTTGTCAAAGATCTAATTGCAGAAATTCTGCATTTTTG
CACAAATGACCAGCTACTCCCCAAAGATCATATTCTAAGTGTATGTGGCTCTGAAGAATT
TTTACAAAACGACCACTGTTTGGGGAGCCACAAAATGTTTCAAAAAGATAAATCTGTTAT
TCAGCTCCACCTGCAGAAAAGTAGGGAAGCTCCAGGAAAGCTATCTCGAAAGCATGAAGA
GGACCACAGTCAGTTTTATCTGAATCAACTTCTAGAATTTATGCATATTTGGAAAGTATC
CAGACAATGTCTCTTAACACTCATCAGAAAATATGACTTCCACCTGAAATACCTATTGAA
AACCCAGGAAAACGTGTATAATATTATTGAAGAAGTTAAAAAAATATGCAGTGTTCTAGG
GTGTGTGGAAACCAAACAAATTACAGATGCAGTAAATGAACTAAGTCTAATTCTTCAGAG
AAAAGGAGAGAATTTTTATCAAAGTTCAGAGACTTCAGCAAAAGGCTTGATAGAGAAGGT
AACAACTGAACTATCCACATCCATCTACCAGCTAATCAATGTCTACTGTAACAGCTTTTA
TGCAGATTTTCAGCCTGTAAATGTACCTAGATGCACTTCCTATCTAAATCCCGGGCTTCC
TTCCCACCTCAGCTTCACAGTGTATGCAGCACACAACATTCCAGAAACCTGGGTGCACAG
CTACAAAGCGTTTTCTTTTACCTGTTGGCTTACATATGCTGGAAAGAAGCTGTGCCAAGT
GAGAAACTACAGAAATATTCCAGACAAGAAATTATTTTTTTTCTTGGTCAACTGGAATGA
AACGATCAATTTTCCCCTTGAAATAAAGTCACTTCCAAGGGAATCCATGCTCACTGTAAA
ACTGTTTGGGATTGCCTGTGCAACCAACAATGCAAATTTACTGGCGTGGACTTGTCTTCC
ACTGTTTCCAAAAGAAAAATCCATTCTCGGGTCTATGCTGTTCAGCATGACATTACAGAG
TGAGCCTCCCGTAGAAATGATAACTCCAGGAGTGTGGGATGTAAGTCAGCCATCCCCGGT
GACCCTGCAGATTGATTTTCCAGCTACTGGGTGGGAGTATATGAAACCTGATTCTGAAGA
GAATAGAAGTAATCTTGAAGAGCCACTAAAGGAGTGTATAAAACATATTGCCAGACTTTC
ACAGAAACAGACTCCCCTACTACTCTCTGAAGAAAAGAAAAGATATTTATGGTTTTATCG
CTTCTACTGCAATAATGAAAACTGCTCCCTTCCTTTAGTCCTGGGTAGTGCCCCTGGATG
GGATGAAAGGACTGTTTCAGAAATGCATACCATTTTGAGAAGATGGACATTTTCTCAACC
TTTAGAGGCTCTTGGGCTTTTGACTTCCAGTTTTCCAGATCAAGAAATTCGTAAAGTGGC
AGTTCAACAATTAGACAACCTCTTGAATGATGAACTACTGGAATATCTCCCACAGCTAGT
TCAGGCTGTCAAGTTTGAATGGAACCTTGAGAGTCCTTTAGTGCAACTTCTACTCCACCG
CTCCTTGCAGAGCATCCAGGTTGCCCATCGTCTTTACTGGCTGCTAAAAAATGCAGAAAA
TGAAGCTTATTTTAAAAGCTGGTATCAGAAGCTACTAGCTGCTCTCCAATTCTGTGCAGG
TAAAGCCTTGAATGATGAGTTTTCCAAGGAGCAGAAACTTATCAAAATTCTGGGAGATAT
TGGGGAAAGAGTCAAGTCTGCCAGTGACCATCAAAGACAGGAGGTACTGAAGAAAGAAAT
TGGCAGACTAGAAGAGTTCTTTCAAGATGTAAATACTTGTCATCTTCCTCTGAACCCTGC
CCTATGTATAAAAGGGATTGATCACGATGCATGTTCATATTTTACATCTAATGCTTTGCC
ATTGAAGATTACTTTCATCAATGCTAATCCGATGGGCAAAAACATCAGCATTATTTTTAA
GGCTGGAGATGATCTTCGTCAGGATATGCTTGTTCTGCAGCTTATTCAAGTGATGGACAA
TATTTGGCTGCAGGAAGGCTTGGATATGCAAATGATCATTTATAGATGTCTATCCACAGG
AAAAGACCAAGGATTGGTGCAGATGGTACCTGATGCTGTGACCCTAGCAAAGATTCATCG
CCATTCTGGACTGATAGGACCATTGAAAGAAAATACAATTAAAAAGTGGTTCAGTCAGCA
CAACCACTTAAAGGCAGATTATGAAAAGGCCTTGAGGAACTTTTTCTACTCCTGTGCTGG
CTGGTGTGTGGTAACATTCATCCTGGGAGTATGTGACCGTCACAATGATAATATCATGCT
GACAAAGTCGGGCCACATGTTTCATATTGACTTTGGAAAATTCTTAGGTCATGCACAAAC
ATTTGGAGGGATAAAAAGGGACCGAGCTCCTTTCATTTTTACTTCAGAGATGGAATACTT
TATTACAGAGGGTGGGAAAAACCCACAGCATTTTCAAGATTTTGTGGAACTTTGCTGTCG
TGCTTATAATATTATCAGAAAGCACAGCCAACTGCTCTTGAACCTGCTGGAAATGATGCT
GTATGCAGGACTGCCTGAGCTAAGTGGAATTCAAGACCTGAAATATGTGTATAATAATCT
TCGTCCACAAGACACAGACCTGGAAGCAACAAGTCATTTTACCAAGAAAATAAAGGAAAG
TCTGGAGTGTTTCCCTGTTAAATTGAATAACTTGATCCACACACTTGCACAAATGTCAGC
CATAAGCCCTGCCAAATCTACTTCACAGACTTTTCCTCAGGAATCCTGTTTGCTGAGTAC
AACTAGGTCGATTGAAAGAGCAACAATTTTAGGGTTCAGCAAGAAATCCAGTAATCTGTA
TCTGATCCAGGTGACACACAGCAACAACGAAACAAGCCTGACAGAAAAATCATTTGAGCA
GTTTTCAAAACTTCACAGCCAACTTCAGAAGCAGTTTGCATCACTGACTCTCCCAGAGTT
TCCTCATTGGTGGCACCTACCTTTTACAAATTCAGATCACAGAAGATTCAGAGATCTAAA
TCATTACATGGAACAGATATTAAATGTATCACATGAAGTTACAAACAGTGATTGTGTACT
TAGCTTTTTCCTCTCTGAGGCTGTGCAACAAACAGTTGAAGAATCATCACCTGTGTACCT
AGGTGAGAAGTTTCCAGACAAGAAGCCTAAGGTGCAGTTAGTCATATCCTACGAGGATGT
GAAGCTGACCATACTAGTGAAACACATGAAAAACATTCATCTCCCAGATGGCTCTGCGCC
CAGTGCACATGTTGAATTTTATCTTTTACCATATCCCAGTGAAGTTCGTAGGAGGAAAAC
AAAATCTGTTCCAAAATGTACGGACCCCACTTACAATGAAATTGTAGTATATGATGAAGT
CACAGAGCTCCAAGGACATGTCTTAATGCTTATTGTGAAGAGTAAAACTGTATTTGTGGG
AGCAATTAACATCCGACTCTGTAGTGTCCCACTCGATAAAGAAAAATGGTATCCATTAGG
AAACAGTATAATTTGACCATTGCTATGAACATATGCATTATTCATTAACTACTTGTATTT
TTTTCACTTCCGGGCCTCTGAATCACATAAGTAAGGCATCTTTGTTGTCAAAGACAGCAC
AGGGTATTAAGGACACAGAAAAAAAATCAGAATTAGTCTTTTGTGTTGTTTATTTTCTAC
CTGTGCTTTCATTGTTTTTTCATAATCTTTTCTCCTTCAGTGGAGTACTGATTGCATGAA
ATTTGATGTGTAAAATAATAAAAGACCTTTATTAAATCATTTTAATATATTTTAAATTAA
ACATAGGTTTACATTTGTTTTAATTGTGTGCCTACAGTTAAAAGCAGTATTTTTAATGTA
TTTTATAAGAAAGACAATCAAATAAACCTCATCAATTAATTCAAAAAAAAAAAAAAAAAA
A
Restriction Sites Please inquire     
ACCN NM_004570
Insert Size 4570 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation The ORF of this clone was fully sequenced and found to contain one SNP compared with NM_004570.2.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_004570.2, NP_004561.1
RefSeq Size 4855 bp
RefSeq ORF 4347 bp
Locus ID 5288
Cytogenetics 12p12.3
Domains C2, PI3_PI4_kinase, PI3Ka, PX, PI3K_C2
Protein Families Druggable Genome
Protein Pathways Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system
Gene Summary 'The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. This gene may play a role in several diseases, including type II diabetes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]'
Transcript Variant: This variant (3) lacks an in-frame exon in the central coding region, compared to variant 1. The encoded isoform (3) is shorter, compared to isoform 1.

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