NFAT5 (NM_138714) Human Untagged Clone

CAT#: SC120670

NFAT5 (untagged)-Human nuclear factor of activated T-cells 5, tonicity-responsive (NFAT5), transcript variant 1


  "NM_138714" in other vectors (6)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol NFAT5
Synonyms NF-AT5; NFATL1; NFATZ; OREBP; TONEBP
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC120670 sequence for NM_138714 edited (data generated by NextGen Sequencing)
ATGGGCGGTGCTTGCAGCTCCTTTACCACCTCTTCCAGCCCTACCATTTATTCTACCTCA
GTCACCGACAGCAAGGCTATGCAAGTGGAGAGCTGCTCCTCAGCCGTGGGGGTAAGTAAC
AGAGGGGTAAGTGAAAAGCAGTTAACCAGTAACACAGTTCAGCAGCATCCATCAACACCG
AAGAGGCACACAGTCTTGTACATCTCACCACCACCTGAGGACTTGCTGGATAACAGTCGG
ATGTCCTGCCAGGATGAGGGGTGTGGATTGGAATCTGAGCAGAGCTGCAGTATGTGGATG
GAGGATTCCCCCTCCAACTTCAGTAACATGAGCACCAGTTCCTACAATGATAACACTGAG
GTACCTCGTAAATCACGAAAACGAAATCCAAAGCAGAGGCCGGGGGTCAAACGACGAGAT
TGTGAAGAATCTAATATGGATATATTTGATGCCGACAGTGCCAAAGCACCTCACTATGTG
CTTTCTCAGCTTACCACGGACAACAAAGGCAACTCAAAAGCGGGAAATGGAACATTGGAA
AACCAAAAAGGAACTGGAGTAAAGAAGAGCCCTATGTTGTGTGGACAATATCCTGTTAAA
AGTGAGGGAAAGGAGCTGAAGATAGTTGTACAACCTGAGACACAGCACCGAGCTCGGTAC
CTGACTGAGGGCAGCCGTGGCTCAGTGAAAGATAGAACACAGCAAGGCTTTCCTACAGTA
AAGCTGGAAGGCCATAATGAACCTGTAGTGTTGCAAGTGTTTGTGGGCAACGACTCTGGA
CGAGTGAAACCACATGGATTTTATCAGGCCTGCAGAGTAACTGGACGAAATACAACTCCT
TGCAAAGAAGTGGACATTGAAGGCACTACTGTTATAGAAGTCGGCCTTGATCCTAGCAAC
AACATGACACTGGCGGTGGACTGCGTAGGGATATTGAAATTGAGGAATGCTGATGTCGAA
GCCAGAATAGGAATTGCTGGTTCCAAGAAGAAAAGCACTCGTGCCAGATTGGTTTTTCGA
GTTAATATCATGAGGAAAGATGGCTCCACTTTGACACTGCAAACACCCTCTTCTCCAATT
TTGTGTACTCAGCCAGCAGGAGTGCCAGAAATCTTAAAGAAAAGCTTGCATAGCTGTTCA
GTGAAAGGAGAAGAAGAAGTGTTTTTAATCGGCAAGAACTTTCTGAAAGGAACTAAAGTT
ATTTTCCAAGAAAATGTTTCTGATGAAAACTCTTGGAAGTCAGAAGCTGAAATTGATATG
GAACTATTTCATCAGAATCATCTTATTGTGAAGGTTCCTCCCTATCATGACCAACATATA
ACTTTGCCTGTGTCAGTGGGAATATATGTAGTGACAAATGCTGGAAGATCTCATGATGTT
CAACCATTCACTTACACTCCAGACCCAGCAGCAGCTGGTGCTTTGAATGTAAATGTGAAG
AAGGAAATATCTAGTCCAGCAAGACCTTGCTCTTTTGAAGAGGCCATGAAAGCAATGAAA
ACTACTGGATGTAATTTAGATAAGGTAAATATTATCCCTAATGCCCTGATGACTCCACTC
ATACCAAGCAGTATGATTAAGAGTGAAGATGTTACTCCAATGGAAGTAACAGCAGAAAAA
AGATCTTCCACTATTTTTAAGACTACAAAGTCTGTTGGATCAACTCAGCAAACATTAGAA
AACATCTCAAACATAGCAGGAAATGGCTCTTTTTCATCACCATCATCTTCCCACCTACCT
TCTGAAAATGAAAAACAGCAGCAGATTCAGCCCAAGGCATACAACCCAGAGACCCTGACA
ACTATTCAAACCCAGGACATCTCACAGCCTGGTACTTTTCCAGCAGTTTCTGCTTCTAGT
CAGCTGCCCAACAGCGATGCACTATTGCAGCAGGCTACACAGTTTCAGACAAGAGAAACT
CAGTCTAGAGAGATATTACAGTCAGATGGTACAGTGGTTAATTTGTCACAACTGACTGAG
GCATCACAACAACAGCAGCAGTCACCACTACAAGAACAAGCACAGACTTTACAGCAGCAG
ATTTCATCAAATATTTTTCCATCACCAAATAGTGTGAGTCAGCTTCAGAATACTATTCAG
CAGCTGCAAGCAGGGAGTTTCACAGGCAGTACTGCTAGTGGCAGCAGTGGAAGTGTTGAC
TTGGTCCAACAAGTTTTAGAGGCACAGCAGCAGTTATCTTCAGTTTTATTTTCTGCTCCA
GATGGTAATGAGAATGTTCAAGAGCAGCTTAGTGCAGATATTTTTCAACAAGTCAGTCAA
ATTCAGAGTGGTGTAAGCCCTGGAATGTTTTCCTCAACAGAGCCAACAGTCCATACCAGA
CCAGATAATTTATTACCTGGAAGAGCTGAAAGTGTTCATCCACAGTCTGAAAACACGTTA
TCTAATCAACAGCAGCAGCAGCAGCAGCAACAGCAAGTGATGGAATCTTCAGCCGCAATG
GTGATGGAGATGCAACAGAGTATCTGCCAGGCAGCTGCCCAGATTCAGTCAGAGTTATTC
CCTTCAACTGCTTCAGCAAATGGAAACCTTCAGCAATCGCCAGTTTACCAGCAGACTTCT
CACATGATGAGTGCATTGTCTACCAATGAGGATATGCAAATGCAGTGTGAATTGTTTTCT
TCTCCTCCTGCAGTTTCTGGAAATGAAACTTCTACAACTACCACACAGCAGGTTGCAACC
CCTGGCACTACCATGTTTCAGACATCAAGTTCAGGAGATGGAGAAGAAACTGGAACACAA
GCAAAACAGATTCAGAACAGTGTCTTTCAGACCATGGTCCAAATGCAACATAGTGGGGAC
AATCAACCTCAAGTTAACCTTTTTTCATCCACAAAAAGTATGATGAGTGTTCAGAATAGT
GGTACCCAACAACAAGGTAATGGTTTATTCCAGCAAGGGAATGAGATGATGTCACTTCAA
TCTGGAAATTTTTTGCAGCAGTCTTCTCATTCACAGGCCCAACTTTTTCATCCTCAAAAT
CCTATTGCCGATGCTCAGAACCTTTCCCAGGAAACTCAAGGTTCTCTCTTTCATAGTCCA
AATCCTATTGTCCACAGTCAGACTTCTACAACCTCCTCTGAACAAATGCAGCCTCCAATG
TTTCACTCTCAAAGTACCATTGCTGTGTTACAGGGCTCTTCAGTTCCTCAAGACCAGCAG
TCAACCAACATATTTCTTTCCCAGAGTCCCATGAATAATCTTCAGACTAACACAGTAGCC
CAAGAAGCATTTTTTGCAGCACCGAACTCAATTTCTCCACTTCAGTCAACATCAAACAGT
GAACAACAAGCTGCTTTCCAACAGCAAGCTCCAATATCACACATCCAGACTCCTATGCTT
TCCCAAGAACAGGCACAACCCCCGCAGCAGGGTTTATTTCAGCCTCAGGTGGCCCTGGGC
TCCCTTCCACCTAATCCAATGCCTCAAAGCCAACAAGGAACCATGTTCCAGTCACAGCAC
TCAATAGTTGCCATGCAGAGTAACTCTCCATCCCAGGAACAGCAGCAGCAGCAGCAACAG
CAGCAGCAACAGCAGCAGCAACAACAACAGAGCATTTTATTCAGTAATCAGAATACCATG
GCTACAATGGCGTCTCCAAAGCAACCACCACCAAACATGATATTCAACCCAAATCAAAAT
CCAATGGCTAATCAGGAGCAACAGAACCAGTCAATTTTTCACCAACAAAGTAACATGGCC
CCAATGAATCAAGAGCAACAGCCCATGCAATTTCAGAGTCAGTCCACAGTTTCCTCACTT
CAGAACCCAGGTCCTACCCAGTCGGAATCATCACAGACCCCCTTGTTCCATAGCTCTCCT
CAGATTCAGTTGGTACAAGGGTCACCTAGTTCTCAAGAGCAGCAAGTAACTCTCTTCTTA
TCTCCAGCATCCATGTCTGCCTTGCAGACCAGTATAAATCAACAAGATATGCAACAGTCT
CCTCTTTATTCCCCTCAGAACAACATGCCTGGAATTCAAGGAGCCACATCTTCGCCTCAA
CCACAGGCTACTTTATTTCACAACACAGCAGGAGGCACAATGAACCAACTGCAGAATTCT
CCTGGCTCATCTCAGCAGACATCAGGAATGTTCTTATTTGGCATTCAAAATAACTGTAGT
CAGCTTTTAACCTCTGGACCAGCTACATTGCCTGATCAGTTGATGGCCATAAGTCAGCCA
GGCCAACCACAAAACGAGGGCCAGCCACCTGTGACAACACTTCTTTCTCAGCAAATGCCA
GAGAATTCTCCACTGGCATCCTCTATAAACACCAACCAGAACATCGAAAAGATTGATTTG
CTTGTTTCATTGCAAAACCAAGGGAACAACTTGACTGGCTCCTTTTAA

Clone variation with respect to NM_138714.3
>OriGene 5' read for NM_138714 unedited
CCACGCCATTCGCACGAGCTCTCCTGGTCTCCGAGAATCAGTCCCCGTGGAGTTCCCCCT
CCACCTCGCCATCGTTTCCTCGGTCCTCGGCCCAGTGGAAGTCACTACCCTCGAGGAGGA
GGCAGCGGCAGCCGCCCTCGCGTCGCCGCCCCCGGTTCGGTGCCCGCGGTCCCGGATAGG
AGTAAGCTGCCGCCACCGCCGCTCCCCCCCTCCCGCTGCCCTTGGGCCGGGCTGGGTCGA
GCTGCGATGCCCTCGGACTTCATCTTATTGCTCAGCGCGGACCTAGACCTGGAATCGCCC
AAGTCCCTCTACTCGCGAGATTCTCTGAAGTTACACCCATCACAGAATTTTCATAGAGCT
GGACTATTGGAAGAATCTGTCTATGATCTTCTCCCAAAGGAGTTACAGTTACCTCCATCT
AGAGAAACATCTGTAGCATCAATGAGTCAGACAAGCGGTGGTGAGGCAGGCTCGCCTCCT
CCAGCTGTTGTTGCTGCTGGATTTGCCTCTGAAGCANGGAGTGTCTGCATTAAAAATGAC
CTGTAGTTCTCTGCTTCATAGATGCTTCTTCAGCTCCCTCCTCTTCCTCCATGGGCGGTG
CTTGCAGCTCCTTTACCACCTCTTCCAGCCCTACCATTTATTCTACCTCAGTCACCGACA
GCAAGGCTATGCAAGTGGAGAGCTGCTCCTCAGCCGTGGGGGTAAGTAACAGAGGGTAAG
TGAAAAGCAGTTAACCGGTACACAGGTCAGCAGCATCCCTCACCCCGAAAAGCACACAGT
CTTGTACATCTTACCCCCCCTGGAGAACTTGCTGGATAACAGTCGGATGTCCTGCCCGGA
AGAGGGGTGTGNTTTGG
>OriGene 3' read for NM_138714 unedited
CTATGGACCGCGGCACGCAATCTAAGATCGAGTTTTTTTTTTTTTTTTTTAATTAAAATT
TATACTCGTTTCCTATTAGGAGGGAAAAATTTGAAGACTTCAGAACAGCACCGTTCATGG
GGAAAAATGTGTTGTTTCTCAGGAATCAACTCCTAATAATTCCTAAGACAGTACTCTCTG
CCCTGTGCTGCAGGATTGCTAGGTCACCCTAGATTAAAGTGGCCAAAGATGCTACAGGGT
CATGAAGCCAGTAGTATATTAATAGTTCTCTAAAGTAAAGTGAAAAAGAGGTGAAAAGTA
ATATAGATATATATAAAAAGGGAATACCAGCCTAAGACTGGGTTAAGAAGAAAACATTCA
AATTTTTCTGTCAATTTAAACTACTGTAGGAGGATATCAGAACATAATTTATCATATATT
ATCCCCTTCATTTTTTACAGATAATTATTTTTCTATGCACAGTTATGGCTAAACCCCTTA
GTAGAAACCCAGAGAACTAACAACTCTCTGAAAAAATAAAATCAAGAAGCATTCCAGCTG
TTCCCAGTTTTATAAGTGTATCATCTGCCTTTGTGTTAAATCAAGAGTACTTTTATCTGC
ACATACAGTTTACTTGTTAGAATGTTACCCTTCAGTTTCTCCAATAAAACTGAAAAAAGA
TTCCCTTCCTTTGGGCCACAGCTGCGCCTTTTATATTGCAAAAAATCCCACCCTTACTAT
TATTGAACCCTTCTTTTTCACAAGCCCTTTACTTGGCTAAAACTTTGCCGGAAACGAAAT
ACTGGATACACCACCCACCCTCATTTTTTTTTTTTTAATACCACACTACCTCGAGGGCCC
CCCCTTATATTAAACCCGCCCTCCAAGGCAATTGCCCCTATGTAAACACCATCCTCTAAT
CCTTGCCGCGGTAACCCAAATAATTCTCCGCTCCTCTCCTTTCGCATCTACATTGGCAAT
CTTCCCTGGCGGTTATACTCTCCCTCCCCACCG
Restriction Sites NotI-NotI     
ACCN NM_138714
ORF Size 4368 bp
Insert Size 6730
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Reference Data
RefSeq NM_138714.2, NP_619728.2
RefSeq Size 14239
RefSeq ORF 4368
Locus ID 10725
Domains IPT
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Axon guidance, B cell receptor signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, VEGF signaling pathway, Wnt signaling pathway
Gene Summary The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Transcript Variant: This variant (1) represents the longest transcript. This variant and variants 4 and 5 encode the same isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

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