MCFD2 (NM_139279) Human Untagged Clone

CAT#: SC120717

MCFD2 (untagged)-Human multiple coagulation factor deficiency 2 (MCFD2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MCFD2
• Synonyms: F5F8D; F5F8D2; LMAN1IP; SDNSF
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_139279 edited
  ATGACCATGAGATCCCTGCTCAGAACCCCCTTCCTGTGTGGCCTGCTCTGGGCCTTTTGT
  GCCCCAGGCGCCAGGGCTGAGGAGCCTGCAGCCAGCTTCTCCCAACCCGGCAGCATGGGC
  CTGGATAAGAACACAGTGCACGACCAAGAGCATATCATGGAGCATCTAGAAGGTGTCATC
  AACAAACCAGAGGCGGAGATGTCGCCACAAGAATTGCAGCTCCATTACTTCAAAATGCAT
  GATTATGATGGCAATAATTTGCTTGATGGCTTAGAACTCTCCACAGCCATCACTCATGTC
  CATAAGGAGGAAGGGAGTGAACAGGCACCACTAATGAGTGAAGATGAACTGATTAACATA
  ATAGATGGTGTTTTGAGAGATGATGACAAGAACAATGATGGATACATTGACTATGCTGAA
  TTTGCAAAATCACTGCAGTAG
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_139279 unedited
  TTCAAATTTTGTAATACGACTTCACTATAGGGCGGCCGCGAATTCGCACGAGGGGGCTGG
  TGAGGCTCACGTTGGAGGGCTTCGCGTCTGCTTCGGAGACCGTAAGGATATTGATGACCA
  TGAGATCCCTGCTCAGAACCCCCTTCCTGTGTGGCCTGCTCTGGGCCTTTTGTGCCCCAG
  GCGCCAGGGCTGAGGAGCCTGCAGCCAGCTTCTCCCAACCCGGCAGCATGGGCCTGGATA
  AGAACACAGTGCACGACCAAGAGCATATCATGGAGCATCTAGAAGGTGTCATCAACAAAC
  CAGAGGCGGAGATGTCGCCACAAGAATTGCAGCTCCATTACTTCAAAATGCATGATTATG
  ATGGCAATAATTTGCTTGATGGCTTAGAACTCTCCACAGCCATCACTCATGTCCATAAGG
  AGGAAGGGAGTGAACAGGCACCACTAATGAGTGAAGATGAACTGATTAACATAATAGATG
  GTGTTTTGAGAGATGATGACAAGAACAATGATGGATACATTGACTATGCTGAATTTGCAA
  AATCACTGCAGTAGATGTTATTTGGCCATCTCCTGGTTATATACAAATGTGACCCGTGAT
  AATGTGATTGAACACTTTAGTAATGCAAAATAACTCATTTCCAACTACTGCTGCAGCATT
  TTGGTAAAAACCTGTAGCGATTCGTTACACTGGGGTGAGAAGAGATAAGAGAAATGAAAG
  AGAAGAGAAATGGGACATCTAATAGTCCCTAAGTGCTATTAAATACCTTATTGGACAANG
  GCTTGCTTCAGCATCTGTATTAGTCTGTATTAATGCTGCTGATAAAGACGTACCCGAGAC
  TGGGAAGAAAAAGAAGTTTACTTGGACCTACAGTTNCACATGGCTGGNGGAGGCCTCAAA
  TCATGGGCGGGAGGGAAAGGCACTTCTTACATGGNCAGCAGAAAAATGAGGAAGAAACAA
  AGGGGAAACCCCTGAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_139279 unedited
  GGTTTGNNNNNAATTCACTNTGNACCGNCGGCCGCATNCTGANGATCGATTTTTTTTTTT
  TTTTTTTTGCTTCATCAGTTTTATTGGTCATATATCCAGNAATCATCATATATAAATCTT
  TCAAAATAATGAGCTATTACAAGAATAGTTTACAAGTCAGCTCTGACTGCACAAATACTT
  GACACAGGAAACCATTTTTACNAATACATATGTTTTCTTATAATACTGTNATAAAGAAAA
  ATAAGTCTGTATACATCCTAACGACAAATTTTGTAGTCTCTTTTTCCCATTCAATCATCG
  TTTCAAGGTTTCTAATACCGAACGTTCCTCCCATCCCATAAACCAATTTCAAACTGGCGG
  CGTCTTTCATTTTCCAAACCCTAAAGAATTCACCGGGGAAAGGGGTTTTGGGGTCCCCTT
  TTAAACTTCCCGAATTGAAAAAAAACCCGTGTCTTGGGCAAAAAAAGGGAAATTCAAACA
  ATTCCCCCTGGAAGAAAAATCCATCGGAGAAAAAAATGGGTGGGGAAAAAATTTTTTACT
  TCCCCCTAGGCAAGGCCCGGGGGGGGTTTTACCCCCCCGGGGAAAAAACCCGGCCATCCC
  CAAAGATTGCCCACCAGGGGGGAAAAAAACCCCCCCCAACCCCGGGGGTAAAAAAGAAAA
  AGCTGCCCCCCCCCTGGTTTGGGGAAACCACACCCCCTTTTGGGGGGGGCCCCCCCGGGG
  GAGAGAAAAACAACAACCCCCCCCCCTTTTTTGGGGGGGGGGGGCGCCTTTTTTTTAAAA
  ACCCCGCAAACGCGGGGGGAGGGGGCCCTTTTCTCCCCGCCGGTGGGTGTTTTCTTCCAA
  GGGGGGGGGGGAGAGGAAAACTTTTTTCTCCCTGGTGGGTGGGGAGAGAAAC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_139279
• ORF Size: 441 bp
• Insert Size: 4700
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_139279.3, NP_644808.1
• RefSeq Size: 4144
• RefSeq ORF: 441
• Locus ID: 90411
• Gene Summary: This gene encodes a soluble luminal protein with two calmodulin-like EF-hand motifs at its C-terminus. This protein forms a complex with LMAN1 (lectin mannose binding protein 1; also known as ERGIC-53) that facilitates the transport of coagulation factors V (FV) and VIII (FVIII) from the endoplasmic reticulum to the Golgi apparatus via an endoplasmic reticulum Golgi intermediate compartment (ERGIC). Mutations in this gene cause combined deficiency of FV and FVIII (F5F8D); a rare autosomal recessive bleeding disorder characterized by mild to moderate bleeding and coordinate reduction in plasma FV and FVIII levels. This protein has also been shown to maintain stem cell potential in adult central nervous system and is a marker for testicular germ cell tumors. The 3' UTR of this gene contains a transposon-like human repeat element named 'THE 1'. A processed RNA pseudogene of this gene is on chromosome 6p22.1. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2016]
  Transcript Variant: This variant (1) encodes isoform A. Variants 1, 2, 3 and 4 encode the same isoform (A).