AKR7L (NM_201252) Human Untagged Clone

CAT#: SC120852

AKR7L (untagged)-Human aldo-keto reductase family 7-like (AKR7L), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: AKR7L
• Synonyms: AFAR3; AKR7A4
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_201252, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTCCCGGCAGCTGTCGCGGGCCCGGCCAGCCACGGTGCTGGGCGCCATGGAGATGGGGCGCCGCATGG
  ACGCGCCCACCAGCGCCGCAGTCACGCGCGCCTTCCTGGAGCGCGGCCACACCGAGATAGACACGGCCTT
  CCTGTACAGCGACGGCCAGTCCGAGACCATCCTTGGCGGCCTGGGGCTCCGAATGGGCAGCAGCGACTGC
  AGAGTGAAAATTGCTACCAAGGCCAATCCATGGATTGGGAACTCCCTGAAGCCTGACAGTGTCCGATCCC
  AGCTGGAGACGTCACTGAAGCGGCTGCAGTGTCCCTGAGTGGACCTCTTCTATCTACATGCACCTGACCA
  CAGCGCCCCGGTGGAAGAGACACTGCGTGCCTGCCACCAGCTGCACCAGGAGGGCAAGTTCGTGGAGCTT
  GGCCTCTCCAACTATGCCGCCTGGGAAGTGGCCGAGATCTGTACCCTCTGCAAGAGCAACGGCTGGATCC
  TGCCCACTGTGTACCAGGGCATGTACAGCGCCACCACCCGGCAGGTGGAAACGGAGCTCTTCCCCTGCCT
  CAGGCACTTTGGACTGAGGTTCTATGCCTACAACCCTCTGGCTGGGGGCCTGCTGACCGGCAAGTACAAG
  TATGAGGACAAGGACGGGAAACAGCCCGTGGGCCGCTTCTTTGGGACTCAGTGGGCAGAGATCTACAGGA
  ATCACTTCTGGAAGGAGCACCACTTCGAGGGCATTGCCCTGGTGGAGAAGGCCCTGCAGGCCGCGTATGG
  CGCCAGCGCTCCCAGCATGACCTCGGCCGCCCTCCGGTGGATGTACCACCACTCACAGCTGCAGGGTGCC
  CACGGGGACGCGGTCATCCTGGGCATGTCCAGCCTGGAGCAGCTGGAGCAGAACTTGGCAGCGGCAGAGG
  AAGGGCCCCTGGAGCCGGCTGTCGTGGACGCCTTTAATCAAGCCTGGCATTTGTTTGCCCACGAATGTCC
  CAACTACTTCATCTAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_201252 unedited
  TAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGACCGTGTTAGCCAGGATG
  GTCTCGAACTCCTGATCTTGTGATCTGCCTGCCTCAGCCCCCCAAAGTGCCGGGATTACA
  GGTGTGAGCCACTGCACCCGGCTGGTTCATGCAATTCTTGTGCCTAGCCTCCCAAGTAGC
  AGAGATAACAGGCGTGTACAACCACCCCCAGCTAATTTTTGTATTTTTAGTACAGATGGG
  GTTTTACCATGTTGGCCAGCTTGGTCTCAAATTCCTGACCTCAGGTCATTTACCCACCTC
  GGCCTCCCAAAGTGCTGGGATTATAGGCATGAGCCACCACATCCAGCCCTGAATTTTCAT
  TTCTCTTTCCTCTCAGTGAAAATTGCTACCAAGGCCAATCCATGGATTGGGAACTCCCTG
  AAGCCTGACAGTGTCCGATCCCAGCTGGAGACGTCACTGAAGCGGCTGCAGTGTCCCCGA
  GTGGACCTCTTCTATCTACATGCACCTGACCACAGCACCCCGGTGGAAGAACACTGCGTG
  CCTGCCACCAGCTGCACCAGGAGGGCAAGTTCGTGGAGCTTGGCCTCTCCAACTATGCCG
  CCTGGGAAGTGGCCGAGATCTGTACCCCTCTGCAAGAGCAACGGCTGGATCCTGCCCACT
  GTGTACCAGGGCATGTACAGCGCCACCACCCGGCAGGTGGGAACGGAGCTCTTCCCCTGC
  CTCAGGCACTTTGGACTGAGGTTCTATGCCTACCACCCTCTGGCTGCTCTTGGAAGGACA
  CCACTTCGAGGCATTGCCCCTATGGAGAGGCCCTGCAGCCGCGTATGGCGCAGCGCTTCC
  ACATGACCTGGCCGCCCTCCGGGGATGACCACCCTCCAGCTGGAGGTGCCACCGGGACCC
  GTATCCTGGGCTGTCCAACTGGACAACTGAACACACTTGGCACGCANAGAAGGN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_201252
• Insert Size: 2600 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_201252.1, NP_957704.1
• RefSeq Size: 2332 bp
• RefSeq ORF: 462 bp
• Locus ID: 246181
• Cytogenetics: 1p35-p36.1
• Protein Families: Druggable Genome
• Gene Summary: This gene is one of three aldo-keto reductase genes that are present in a cluster on the p arm of chromosome 1. The encoded proteins are involved in the reduction of the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. It has been speculated that this family member encodes a selenoprotein, which includes a selenocysteine (Sec) residue in lieu of a UGA translational termination codon. However, there is no evidence that such a protein is produced in vivo. The alternative interpretation is that this family member is a segregating pseudogene, where some individuals have an allele that encodes a functional enzyme, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Feb 2017]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).